[Hub]/) : Traits : Cholesterol lowering medication :

chr16:71,374,298-72,800,567

Best TWAS P=7.91e-08 · Best GWAS P=1.96e-07 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HPR 0.72 0.60 lasso 7 0.61 6.9e-94 5.2 5.3 9.1e-08 1.00 0 1 FALSE
2 CommonMind Brain Pre-frontal Cortex TXNL4B 0.05 0.07 lasso 3 0.06 8.8e-08 5.2 5.2 2.6e-07 0.97 0 1 FALSE
3 The Cancer Genome Atlas Glioblastoma Multiforme HPR 0.82 0.49 lasso 3 0.47 3.4e-16 5.2 5.3 1.4e-07 1.00 0 1 FALSE
4 The Cancer Genome Atlas Brain Lower Grade Glioma HP 0.60 0.42 lasso 5 0.41 3.8e-50 5.2 5.3 1.3e-07 1.00 0 1 FALSE
5 The Cancer Genome Atlas Brain Lower Grade Glioma HPR 0.75 0.56 lasso 4 0.56 6.1e-76 5.2 5.2 1.5e-07 1.00 0 1 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma TXNL4B 0.44 0.29 lasso 4 0.29 3.2e-33 5.2 5.4 7.9e-08 0.99 0 1 TRUE