Best TWAS P=7.91e-08 · Best GWAS P=1.96e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HPR | 0.72 | 0.60 | lasso | 7 | 0.61 | 6.9e-94 | 5.2 | 5.3 | 9.1e-08 | 1.00 | 0 | 1 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | TXNL4B | 0.05 | 0.07 | lasso | 3 | 0.06 | 8.8e-08 | 5.2 | 5.2 | 2.6e-07 | 0.97 | 0 | 1 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | HPR | 0.82 | 0.49 | lasso | 3 | 0.47 | 3.4e-16 | 5.2 | 5.3 | 1.4e-07 | 1.00 | 0 | 1 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | HP | 0.60 | 0.42 | lasso | 5 | 0.41 | 3.8e-50 | 5.2 | 5.3 | 1.3e-07 | 1.00 | 0 | 1 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | HPR | 0.75 | 0.56 | lasso | 4 | 0.56 | 6.1e-76 | 5.2 | 5.2 | 1.5e-07 | 1.00 | 0 | 1 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TXNL4B | 0.44 | 0.29 | lasso | 4 | 0.29 | 3.2e-33 | 5.2 | 5.4 | 7.9e-08 | 0.99 | 0 | 1 | TRUE |