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chr17:27,207,120-28,933,576

Best TWAS P=1.84e-08 · Best GWAS P=3.69e-08 conditioned to 0.257

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Nerve Tibial SSH2 0.05 0.06 lasso 10 0.06 7.8e-05 -5.3 -5.3 1.2e-07 0.99 0.07 0.92 FALSE
2 GTEx Spleen GIT1 0.15 0.06 lasso 5 0.06 1.4e-02 5.3 5.3 1.5e-07 -0.77 0.07 0.68 FALSE
3 GTEx Thyroid GIT1 0.06 0.08 lasso 5 0.09 3.7e-07 5.5 -5.6 1.8e-08 0.88 0.05 0.95 TRUE
4 GTEx Thyroid SSH2 0.12 0.17 enet 10 0.18 2.0e-13 5.3 -5.3 1.2e-07 0.84 0.05 0.95 FALSE
5 GTEx Thyroid CORO6 0.23 0.36 lasso 5 0.37 1.2e-29 5.3 -5.2 1.6e-07 0.82 0.05 0.95 FALSE
6 YFS Blood GIT1 0.11 0.08 lasso 8 0.09 8.7e-27 -4.4 5.5 4.4e-08 -0.78 0.73 0.26 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma SSH2 0.01 0.01 blup 111 0.01 1.0e-03 4.9 -5.2 2.5e-07 0.98 0.06 0.92 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SSH2 0.03 0.02 blup 112 0.03 2.4e-04 -5.1 -5.4 6.2e-08 0.98 0.04 0.95 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma EFCAB5 0.06 0.09 lasso 1 0.09 2.9e-10 -5.3 -5.3 1.1e-07 0.99 0.01 0.99 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma SSH2 0.06 0.03 blup 112 0.05 2.5e-06 5.3 -5.6 2.5e-08 0.95 0.04 0.95 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma ANKRD13B 0.14 0.20 lasso 4 0.19 2.2e-18 5.3 -5.2 2.0e-07 0.82 0.01 0.99 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma CORO6 0.28 0.40 lasso 3 0.39 6.2e-40 5.3 -5.3 1.4e-07 0.82 0.01 0.99 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma SSH2 0.25 0.18 lasso 5 0.17 4.8e-16 5.3 -5.4 6.7e-08 0.85 0.03 0.97 FALSE