Best TWAS P=2.34e-13 · Best GWAS P=2.07e-86 conditioned to 6.7e-65
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | PVRL2 | 0.15 | 0.01 | enet | 10 | 0.02 | 1.7e-02 | -6.1 | 5.5 | 3.2e-08 | -0.16 | 0.14 | 0.04 | FALSE |
| 2 | YFS | Blood | TOMM40 | 0.04 | 0.00 | bslmm | 371 | 0.01 | 2.6e-04 | -6.6 | 6.3 | 2.9e-10 | -0.08 | 0.05 | 0.02 | TRUE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | APOC2 | 0.18 | 0.12 | enet | 14 | 0.13 | 5.2e-06 | -1.4 | 6.1 | 8.1e-10 | -0.19 | 0.64 | 0.05 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | PVRL2 | 0.09 | 0.05 | blup | 55 | 0.03 | 4.6e-04 | 1.6 | -7.3 | 2.3e-13 | 0.31 | 0.46 | 0.09 | TRUE |