TWAS
hub
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Usage
Models
Genes
Traits
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Traits
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Cholesterol lowering medication
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chr20:39,567,774-40,229,720
Best TWAS P=3.96e-08 · Best GWAS P=1.86e-07 conditioned to 0.0608
39.6M
39.7M
39.8M
39.9M
40M
40.1M
40.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
LPIN3
0.10
0.02
lasso
5
0.07
6.1e-04
4.9
5.5
4.0e-08
0.71
0.01
0.55
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
ZHX3
0.05
0.06
lasso
2
0.05
2.6e-06
5.1
-5.2
2.5e-07
-0.99
0.01
0.99
FALSE