Best TWAS P=3.96e-08 · Best GWAS P=1.86e-07 conditioned to 0.0608
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | LPIN3 | 0.10 | 0.02 | lasso | 5 | 0.07 | 6.1e-04 | 4.9 | 5.5 | 4.0e-08 | 0.71 | 0.01 | 0.55 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZHX3 | 0.05 | 0.06 | lasso | 2 | 0.05 | 2.6e-06 | 5.1 | -5.2 | 2.5e-07 | -0.99 | 0.01 | 0.99 | FALSE |