Best TWAS P=7.05e-08 · Best GWAS P=1.85e-07 conditioned to 0.634
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | 5.2 | 5.2 | 2.3e-07 | 0.98 | 0 | 1 | FALSE |
2 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | 5.2 | 5.4 | 7.1e-08 | 0.94 | 0 | 1 | TRUE |