[Hub]/) : Traits : Medication: Blood pressure :

chr11:46,570,859-47,977,454

Best TWAS P=3.29e-09 · Best GWAS P=4.84e-08 conditioned to 0.361

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Hypothalamus NR1H3 0.25 0.18 lasso 5 0.10 2.7e-03 -5.4 -5.5 4.5e-08 0.99 0.02 0.87 FALSE
2 GTEx Cells EBV-transformed lymphocytes ACP2 0.17 0.03 lasso 6 0.03 4.2e-02 -5.1 5.9 3.3e-09 -0.84 0.03 0.92 TRUE
3 GTEx Esophagus Mucosa ACP2 0.07 0.04 enet 11 0.04 6.2e-04 -4.9 5.4 5.6e-08 -0.85 0.04 0.95 FALSE
4 GTEx Lung ACP2 0.04 0.03 lasso 2 0.04 4.3e-04 -5.1 5.6 2.2e-08 -0.95 0.03 0.95 FALSE
5 GTEx Testis NR1H3 0.10 0.10 lasso 6 0.08 2.9e-04 -5.1 5.3 9.3e-08 -0.95 0.02 0.97 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ACP2 0.03 0.03 blup 44 0.04 3.5e-05 -5.1 5.5 3.8e-08 -0.95 0.01 0.98 FALSE