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chr11:1,213,806-2,705,175

Best TWAS P=1.19e-15 · Best GWAS P=8.72e-17 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LSP1	0.12	0.08	lasso	5	0.10	5.0e-11	-7.0	-8.0	1.2e-15	-0.60	0.06	0.94	TRUE
15	YFS	Blood	TNNT3	0.02	0.02	lasso	3	0.01	1.9e-05	7.4	-7.1	1.8e-12	-0.81	0.04	0.96	TRUE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC100133545	0.03	0.01	blup	49	0.01	1.1e-02	4.8	5.7	1.5e-08	0.39	0.00	0.80	TRUE
1	GTEx	Artery Aorta	TNNT3	0.21	-0.01	enet	17	0.00	6.4e-01	-1.3	-5.4	5.3e-08	-0.30	0.05	0.06	TRUE
11	GTEx	Nerve Tibial	MRPL23-AS1	0.18	0.11	lasso	4	0.16	1.2e-11	4.8	5.4	5.4e-08	0.43	1.00	0.00	TRUE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LOC100133545	0.06	0.02	blup	49	0.03	6.7e-03	-4.2	5.4	6.7e-08	0.37	0.04	0.49	TRUE
4	GTEx	Brain Caudate basal ganglia	MRPL23-AS1	0.26	0.07	enet	11	0.10	6.3e-04	3.7	5.3	1.4e-07	0.41	0.24	0.06	TRUE
8	GTEx	Breast Mammary Tissue (Female)	MRPL23-AS1	0.24	0.06	lasso	4	0.01	1.9e-01	4.5	5.2	2.3e-07	0.29	0.08	0.05	TRUE
12	GTEx	Skin Not Sun Exposed Suprapubic	TNNT3	0.33	0.16	lasso	7	0.17	2.0e-09	7.4	7.7	1.2e-14	0.91	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LSP1	0.07	0.03	lasso	4	0.03	2.4e-04	6.5	-7.7	1.9e-14	-0.35	0.09	0.24	FALSE
9	GTEx	Cells Transformed fibroblasts	LSP1	0.21	0.04	enet	28	0.06	3.4e-05	8.3	7.0	2.4e-12	0.72	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TNNI2	0.11	0.09	lasso	2	0.08	4.1e-06	6.5	-6.5	6.7e-11	-0.19	0.60	0.07	FALSE
6	GTEx	Brain Frontal Cortex BA9	MRPL23-AS1	0.36	0.23	lasso	3	0.21	3.8e-06	6.2	6.0	1.6e-09	0.49	0.34	0.30	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	LSP1	0.06	0.04	enet	6	0.04	3.1e-05	6.6	6.0	1.6e-09	0.11	0.64	0.06	FALSE
2	GTEx	Artery Aorta	MRPL23-AS1	0.22	0.07	enet	10	0.12	2.9e-07	6.2	5.9	4.8e-09	0.45	0.97	0.01	FALSE
14	GTEx	Skin Sun Exposed Lower leg	MRPL23-AS1	0.19	0.19	enet	9	0.21	5.3e-17	4.7	5.9	4.9e-09	0.45	1.00	0.00	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	MRPL23-AS1	0.33	0.19	enet	30	0.21	9.5e-12	4.8	5.7	9.5e-09	0.37	1.00	0.00	FALSE
10	GTEx	Esophagus Muscularis	MRPL23-AS1	0.21	0.07	lasso	4	0.10	1.8e-06	4.7	5.4	8.8e-08	0.44	0.93	0.01	FALSE
3	GTEx	Artery Tibial	MRPL23-AS1	0.27	0.10	lasso	6	0.19	1.5e-14	3.7	5.3	1.2e-07	0.43	1.00	0.00	FALSE
5	GTEx	Brain Cerebellum	MRPL23-AS1	0.25	0.14	enet	12	0.18	6.8e-06	4.7	5.3	1.2e-07	0.46	0.27	0.24	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC100133545	0.04	0.02	enet	7	0.03	4.4e-07	-4.5	5.2	1.9e-07	0.37	0.06	0.89	FALSE
7	GTEx	Breast Mammary Tissue	MRPL23-AS1	0.30	0.15	lasso	5	0.19	6.4e-10	4.5	5.1	2.7e-07	0.29	1.00	0.00	FALSE