Best TWAS P=2.1e-09 · Best GWAS P=3.82e-09 conditioned to 0.0191
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RNASEH2C | 0.05 | 0.00 | blup | 32 | 0.02 | 1.1e-04 | 1.5 | -5.6 | 1.9e-08 | 0.42 | 0.01 | 0.05 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SIPA1 | 0.06 | 0.04 | blup | 43 | 0.05 | 4.6e-06 | -4.4 | 6.0 | 2.1e-09 | -0.52 | 0.01 | 0.98 | TRUE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RNASEH2C | 0.15 | 0.05 | blup | 32 | 0.05 | 3.1e-06 | 1.5 | -5.9 | 3.4e-09 | 0.48 | 0.17 | 0.01 | TRUE |
4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SIPA1 | 0.04 | 0.00 | blup | 43 | 0.02 | 6.2e-03 | -5.6 | 5.8 | 8.1e-09 | -0.59 | 0.00 | 0.69 | FALSE |
5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SIPA1 | 0.09 | 0.03 | blup | 43 | 0.06 | 1.2e-07 | -5.6 | 5.1 | 2.8e-07 | -0.33 | 0.00 | 1.00 | FALSE |