Best TWAS P=4.41e-19 · Best GWAS P=3.69e-19 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ARHGAP42 | 0.22 | 0.15 | enet | 18 | 0.19 | 1.7e-10 | -8.4 | -8.0 | 1.4e-15 | 0.86 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | TMEM133 | 0.30 | 0.15 | enet | 34 | 0.19 | 7.1e-11 | -8.9 | -7.1 | 9.1e-13 | 0.72 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | -8.9 | -8.9 | 4.4e-19 | 0.98 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | -8.9 | -8.8 | 9.4e-19 | 0.94 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Cells Transformed fibroblasts | ARHGAP42 | 0.15 | 0.10 | enet | 20 | 0.08 | 2.6e-06 | 5.3 | -5.4 | 6.0e-08 | 0.46 | 0.71 | 0.23 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ARHGAP42 | 0.04 | 0.01 | blup | 266 | 0.02 | 1.1e-04 | 3.5 | -5.2 | 2.0e-07 | 0.57 | 0.04 | 0.88 | FALSE |