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chr16:3,462,595-5,510,848

Best TWAS P=4.96e-11 · Best GWAS P=3.73e-10 conditioned to 0.00128

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Heart Left Ventricle	MGRN1	0.32	0.10	enet	18	0.33	3.6e-18	3.2	6.6	5.0e-11	-0.56	0.50	0.49	TRUE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TRAP1	0.11	0.01	blup	43	0.05	9.4e-04	-3.1	5.2	1.7e-07	0.01	0.00	0.01	TRUE
7	GTEx	Muscle Skeletal	MGRN1	0.16	0.06	lasso	7	0.15	1.1e-14	3.6	6.2	6.0e-10	-0.51	0.83	0.16	FALSE
11	METSIM	Adipose	NUDT16L1	0.06	0.03	bslmm	392	0.04	2.2e-06	-4.5	-6.0	1.9e-09	0.84	0.01	0.99	FALSE
5	GTEx	Heart Atrial Appendage	MGRN1	0.33	0.30	enet	13	0.32	7.1e-15	-4.2	5.8	6.8e-09	-0.71	0.82	0.17	FALSE
1	GTEx	Artery Tibial	ZNF500	0.19	0.18	lasso	5	0.17	1.8e-13	-5.0	-5.3	8.9e-08	0.92	0.02	0.98	FALSE
10	GTEx	Thyroid	MGRN1	0.30	0.24	enet	32	0.33	6.8e-26	-4.1	5.3	9.7e-08	-0.78	0.85	0.15	FALSE
9	GTEx	Testis	NUDT16L1	0.38	0.49	enet	16	0.38	5.9e-18	-4.7	-5.3	1.2e-07	0.89	0.27	0.73	FALSE
3	GTEx	Breast Mammary Tissue	ZNF500	0.18	0.10	lasso	3	0.10	5.0e-06	-4.7	-5.2	1.8e-07	0.87	0.30	0.70	FALSE
8	GTEx	Spleen	MGRN1	0.55	0.45	lasso	3	0.42	4.3e-12	-5.1	5.2	2.5e-07	-0.89	0.13	0.87	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	C16orf71	0.01	0.01	blup	52	0.01	3.1e-03	-5.2	-5.2	2.6e-07	0.88	0.06	0.69	FALSE
2	GTEx	Brain Hypothalamus	MGRN1	0.28	0.15	lasso	7	0.15	2.8e-04	-5.1	5.1	2.7e-07	-0.89	0.12	0.64	FALSE
4	GTEx	Breast Mammary Tissue (Female)	ZNF500	0.14	0.10	lasso	3	0.05	1.7e-02	-5.0	-5.1	2.9e-07	0.84	0.06	0.78	FALSE