[Hub]/) : Traits : Medication: Blood pressure : ← →

chr1:112,312,154-114,196,883

Best TWAS P=7.31e-18 · Best GWAS P=4e-15 conditioned to 0.393

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Thyroid Carcinoma	RHOC	0.04	0.03	enet	9	0.04	1.4e-04	-7.9	-8.6	7.3e-18	0.90	0.01	0.98	TRUE
10	ROSMAP	Brain Pre-frontal Cortex	CAPZA1	0.05	0.06	lasso	3	0.06	1.1e-07	-5.9	-5.9	2.7e-09	0.77	1.00	0.00	TRUE
11	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	WNT2B	0.09	0.02	enet	13	0.04	5.1e-03	-6.2	-5.8	5.3e-09	0.64	0.02	0.03	TRUE
7	GTEx	Skin Not Sun Exposed Suprapubic	SLC16A1	0.12	0.00	lasso	5	0.04	5.0e-03	5.3	-5.4	7.2e-08	0.20	0.11	0.45	TRUE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	WNT2B	0.05	0.02	blup	46	0.05	4.7e-04	-5.9	-7.6	2.6e-14	0.67	0.06	0.11	FALSE
4	GTEx	Muscle Skeletal	WNT2B	0.06	0.02	lasso	7	0.03	9.4e-04	-6.1	-6.7	2.0e-11	0.83	0.03	0.94	FALSE
1	CommonMind	Brain Pre-frontal Cortex	WNT2B	0.43	0.46	enet	44	0.47	7.4e-64	5.6	6.4	2.0e-10	-0.27	1.00	0.00	FALSE
3	GTEx	Breast Mammary Tissue (Male)	WNT2B	0.18	0.07	lasso	6	0.05	2.3e-02	-6.2	-6.2	5.4e-10	0.76	0.07	0.22	FALSE
6	GTEx	Nerve Tibial	RP4-671G15.2	0.07	0.06	lasso	2	0.06	2.9e-05	-5.9	6.1	1.0e-09	-0.77	0.83	0.12	FALSE
2	GTEx	Artery Aorta	WNT2B	0.15	0.01	enet	7	0.01	1.0e-01	-6.2	-6.0	2.1e-09	0.75	0.06	0.75	FALSE
9	GTEx	Skin Sun Exposed Lower leg	RHOC	0.07	0.02	lasso	3	0.02	1.5e-02	-5.9	-5.9	3.1e-09	0.72	0.15	0.72	FALSE
8	GTEx	Skin Sun Exposed Lower leg	MOV10	0.05	0.02	lasso	5	0.02	1.1e-02	5.3	5.7	9.0e-09	-0.51	0.20	0.42	FALSE
5	GTEx	Nerve Tibial	CAPZA1	0.17	0.16	lasso	4	0.16	2.4e-11	-6.0	-5.5	3.9e-08	0.75	0.99	0.01	FALSE