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chr3:48,618,666-50,448,632

Best TWAS P=7e-08 · Best GWAS P=2.47e-06 conditioned to 0.341

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous TCTA 0.05 0.01 enet 10 0.01 5.8e-02 4.5 -5.2 2.5e-07 -0.56 0.06 0.64 FALSE
2 GTEx Adipose Subcutaneous NICN1 0.20 0.12 lasso 17 0.13 6.7e-11 4.3 -5.2 1.6e-07 -0.67 0.10 0.86 FALSE
3 GTEx Brain Cerebellum GPX1 0.31 0.09 enet 19 0.23 2.0e-07 -4.0 5.3 9.3e-08 0.67 0.21 0.67 FALSE
4 GTEx Brain Frontal Cortex BA9 GPX1 0.16 0.06 lasso 6 0.15 7.9e-05 4.2 5.2 1.9e-07 0.56 0.10 0.50 FALSE
5 GTEx Cells EBV-transformed lymphocytes USP4 0.08 0.05 lasso 2 0.09 8.7e-04 4.7 5.2 1.7e-07 0.63 0.07 0.64 FALSE
6 GTEx Esophagus Gastroesophageal Junction RNF123 0.14 0.13 enet 30 0.10 2.3e-04 4.6 5.4 7.0e-08 0.94 0.05 0.90 TRUE
7 GTEx Esophagus Muscularis GPX1 0.13 0.05 lasso 14 0.06 1.1e-04 -4.1 5.3 1.3e-07 0.58 0.19 0.71 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma GMPPB 0.13 0.08 blup 40 0.09 2.7e-04 4.6 5.2 1.7e-07 0.93 0.01 0.76 FALSE