TWAS hub - NICN1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0920	0.0470	3.2e-06	0.031	0.035	0.030	0.037	0.032	1.0e-04	3.6e-05	1.2e-04	2.5e-05	7.0e-05
2	GTEx	Adipose Subcutaneous	0.1960	0.0980	8.9e-10	0.122	NA	0.128	NA	0.132	3.4e-10	NA	1.2e-10	NA	6.7e-11
3	GTEx	Adipose Visceral Omentum	0.0880	0.0500	6.7e-04	0.061	NA	0.019	NA	0.039	4.1e-04	NA	3.3e-02	NA	4.1e-03
4	GTEx	Artery Aorta	0.1490	0.0530	9.7e-11	0.210	NA	0.206	NA	0.202	9.2e-12	NA	1.4e-11	NA	2.3e-11
5	GTEx	Artery Coronary	0.0970	0.0570	5.9e-03	0.011	NA	0.007	NA	0.011	1.3e-01	NA	1.7e-01	NA	1.3e-01
6	GTEx	Artery Tibial	0.2004	0.0693	2.2e-14	0.168	NA	0.234	NA	0.230	3.9e-13	NA	3.0e-18	NA	5.9e-18
7	GTEx	Brain Nucleus accumbens basal ganglia	0.1590	0.0820	1.2e-03	0.102	NA	0.024	NA	0.086	1.1e-03	NA	7.5e-02	NA	2.7e-03
8	GTEx	Breast Mammary Tissue	0.0780	0.0360	3.9e-05	0.082	NA	0.082	NA	0.082	5.5e-05	NA	5.2e-05	NA	5.2e-05
9	GTEx	Breast Mammary Tissue (Female)	0.0147	0.0276	3.2e-01	0.004	NA	-0.010	NA	0.010	2.3e-01	NA	8.7e-01	NA	1.6e-01
10	GTEx	Cells Transformed fibroblasts	0.0630	0.0380	4.1e-04	0.058	NA	0.047	NA	0.048	3.5e-05	NA	1.8e-04	NA	1.6e-04
11	GTEx	Colon Transverse	0.0650	0.0370	2.5e-03	0.076	NA	0.061	NA	0.076	1.8e-04	NA	7.2e-04	NA	1.8e-04
12	GTEx	Esophagus Mucosa	0.0770	0.0370	2.9e-05	0.074	NA	0.053	NA	0.053	1.2e-05	NA	1.9e-04	NA	1.9e-04
13	GTEx	Esophagus Muscularis	0.1050	0.0430	5.4e-06	0.025	NA	0.075	NA	0.065	1.1e-02	NA	2.7e-05	NA	8.6e-05
14	GTEx	Lung	0.1178	0.0488	4.1e-09	0.123	NA	0.146	NA	0.137	1.1e-09	NA	2.6e-11	NA	1.2e-10
15	GTEx	Muscle Skeletal	0.0476	0.0240	8.1e-05	0.057	NA	0.057	NA	0.057	2.6e-06	NA	2.8e-06	NA	2.7e-06
16	GTEx	Nerve Tibial	0.1297	0.0462	9.0e-11	0.151	NA	0.162	NA	0.153	7.3e-11	NA	1.4e-11	NA	5.3e-11
17	GTEx	Ovary	0.1420	0.0770	4.0e-03	0.067	NA	0.023	NA	0.058	1.0e-02	NA	9.2e-02	NA	1.5e-02
18	GTEx	Skin Not Sun Exposed Suprapubic	0.0700	0.0360	7.2e-05	0.094	NA	0.086	NA	0.100	7.8e-06	NA	1.8e-05	NA	4.2e-06
19	GTEx	Skin Sun Exposed Lower leg	0.0700	0.0310	3.7e-06	0.092	NA	0.071	NA	0.077	4.7e-08	NA	1.5e-06	NA	5.6e-07
20	GTEx	Thyroid	0.2740	0.0790	0.0e+00	0.326	NA	0.336	NA	0.341	1.4e-25	NA	1.9e-26	NA	5.6e-27
21	GTEx	Uterus	0.1100	0.0640	7.1e-03	0.091	NA	0.044	NA	0.069	6.8e-03	NA	4.7e-02	NA	1.6e-02
22	ROSMAP	Brain Pre-frontal Cortex	0.0766	0.0378	2.4e-06	0.050	0.039	0.054	0.041	0.049	5.0e-07	8.3e-06	1.8e-07	4.2e-06	5.5e-07
23	YFS	Blood	0.1510	0.0459	0.0e+00	0.205	0.220	0.219	0.219	0.218	4.6e-65	3.5e-70	4.6e-70	5.8e-70	1.3e-69

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Frequency of tiredness / lethargy in last 2 weeks	21.7	35.2	46.4	4.2	-6.1	-6.6	-6.2	-6.0	-4.6	6.4	-6.6	-4.7	-6.8	-6.5	-6.4	-4.8	-6.4	-6.3	-6.1	-5.2	-6.1	-6.2	-6.2	-5.6	5.0	6.3
Miserableness	16.6	28.8	43.3	1.8	-6.6	-5.7	-5.8	-6.1	-5.1	5.3	-6.0	-4.9	-5.2	-5.6	-5.2	-6.2	-6.4	-5.1	-6.3	-5.4	-5.6	-5.0	-5.7	-4.4	3.3	4.5
Ulcerative Colitis (UC)	16.0	30.1	76.8	-1.5	7.1	4.5	6.1	7.0	7.6	-4.6	4.5	3.3	4.9	4.5	4.2	8.8	6.6	4.6	7.3	6.7	3.6	4.7	5.4	5.0	-3.6	-4.3
Medication: Paracetamol	14.8	22.9	31.0	1.6	-5.6	-5.1	-5.3	-5.4	-4.5	4.7	-5.1	-4.4	-5.2	-5.0	-4.9	-5.3	-5.5	-4.8	-5.4	-4.5	-4.9	-4.7	-5.2	-4.0	3.0	4.3
Age when periods started (menarche)	14.4	34.6	45.6	1.4	-6.7	-6.3	-6.5	-6.5	-5.9	5.8	-6.5	-5.6	-6.7	-6.3	-6.1	-6.2	-6.8	-6.0	-6.7	-5.2	-5.5	-5.9	-6.4	-4.8	3.4	5.3
Frequency of tenseness / restlessness in last 2 weeks	14.4	22.4	27.1	2.7	-5.2	-5.0	-5.0	-5.1	-4.7	4.8	-5.1	-4.5	-4.8	-4.9	-4.9	-4.7	-5.2	-4.8	-5.2	-4.6	-4.7	-4.8	-5.1	-4.3	3.6	4.5
Fed-up feelings	13.5	24.5	46.6	1.7	-6.4	-4.9	-5.3	-6.0	-5.7	4.6	-5.0	-3.4	-4.5	-4.9	-4.4	-6.8	-6.1	-4.4	-6.3	-5.4	-4.8	-4.4	-5.0	-4.0	2.8	3.8
Pulse rate, automated reading	13.1	42.2	77.6	-7.8	4.7	6.3	6.3	5.0	2.6	-7.3	6.6	5.5	7.7	6.7	7.1	1.8	4.9	7.5	4.3	6.1	6.6	7.3	6.7	8.1	-8.8	-8.4
Smoking Status	13.0	31.1	37.1	3.6	-6.1	-5.8	-6.0	-6.0	-4.5	5.7	-6.1	-5.7	-5.9	-5.9	-5.6	-5.3	-6.1	-5.7	-6.1	-5.2	-5.8	-5.7	-5.8	-5.3	4.4	5.6
Depressed Affect (Nagel 2018)	12.7	26.8	42.6	1.7	-6.5	-5.3	-5.5	-6.1	-5.5	4.9	-5.6	-4.4	-4.9	-5.3	-4.9	-6.3	-6.2	-4.9	-6.4	-5.1	-5.3	-4.9	-5.5	-4.1	3.0	4.2
Pulse rate	12.7	21.4	30.7	-4.8	3.7	4.7	4.7	3.9	2.6	-5.2	4.8	3.9	5.3	5.0	5.1	2.1	4.0	5.3	3.6	4.4	4.7	5.2	4.9	5.5	-5.4	-5.5
Chest pain or discomfort	12.1	17.4	22.0	1.8	-4.7	-4.4	-4.5	-4.7	-3.5	4.2	-4.5	-3.7	-4.4	-4.4	-4.5	-4.0	-4.6	-4.5	-4.5	-3.5	-4.6	-4.5	-4.7	-3.6	2.5	4.1
Ever depressed for a whole week	11.9	14.7	20.0	2.2	-3.8	-4.3	-4.0	-3.6	-2.4	4.1	-4.5	-4.4	-4.2	-4.1	-4.0	-2.7	-3.9	-3.9	-3.8	-3.6	-4.2	-4.0	-4.1	-3.8	3.5	4.1
Pack years adult smoking proportion	11.8	17.9	23.9	3.2	-4.9	-4.1	-4.3	-4.7	-3.3	4.3	-4.2	-3.3	-3.8	-4.2	-4.3	-4.3	-4.6	-4.3	-4.7	-4.7	-4.5	-4.3	-4.4	-4.3	4.2	4.1
Medication: Paracetamol	11.8	19.6	27.5	1.6	-5.2	-4.7	-4.9	-4.9	-3.7	4.3	-4.8	-4.2	-4.9	-4.6	-4.5	-4.9	-5.1	-4.4	-5.1	-4.2	-4.7	-4.3	-4.8	-3.7	2.8	3.9
Pain all over the body in last month	11.7	12.5	17.1	1.5	-4.0	-3.4	-3.8	-3.9	-3.5	3.4	-3.6	-3.3	-3.3	-3.4	-3.3	-4.0	-3.9	-3.3	-4.1	-4.1	-3.2	-3.3	-3.7	-3.7	3.4	3.3
Irritable Bowel Disease (IBD)	11.6	27.7	104.0	0.1	7.4	3.7	5.6	7.3	8.7	-3.7	3.5	1.7	3.9	3.6	3.1	10.2	6.6	3.5	7.7	7.2	2.2	3.6	4.6	4.2	-2.8	-3.0
Ulcerative Colitis	11.6	16.9	47.9	-0.9	5.5	3.4	4.4	5.4	6.7	-3.3	3.3	2.0	3.7	3.4	3.0	6.9	5.1	3.3	5.6	4.7	2.0	3.4	3.9	3.1	-1.9	-2.9
Qualifications: College or University degree	11.2	35.4	106.1	1.3	8.1	4.6	6.4	7.9	8.1	-4.2	5.4	6.0	4.8	4.6	3.8	10.3	7.3	4.5	8.7	7.1	4.5	4.3	6.0	4.2	-2.2	-3.5
Impedance of arm (left)	10.9	50.6	69.1	-3.8	8.3	6.9	7.3	8.0	5.9	-7.0	7.5	7.6	6.4	7.0	7.0	6.9	7.7	7.0	8.0	7.8	6.6	7.1	7.7	7.2	-6.7	-6.9
Number of full brothers	10.6	13.4	18.2	3.1	-4.0	-3.7	-3.7	-3.8	-2.0	3.8	-3.8	-3.7	-3.8	-3.7	-3.6	-3.2	-3.9	-3.6	-3.8	-3.7	-4.3	-3.7	-3.8	-3.6	3.6	3.9
Ever unenthusiastic/disinterested for a whole week	10.3	12.6	19.0	1.7	-3.7	-3.8	-3.8	-3.5	-2.7	3.6	-4.1	-4.4	-3.9	-3.8	-3.7	-2.8	-3.7	-3.6	-3.7	-3.2	-3.8	-3.6	-3.9	-3.3	2.9	3.6
Major Depression (MDD)	10.2	12.4	17.5	1.5	-4.0	-4.0	-3.6	-3.8	-2.4	3.6	-4.1	-4.2	-3.3	-3.8	-3.8	-3.4	-4.0	-3.7	-4.0	-3.0	-4.1	-3.5	-3.7	-2.8	2.0	3.1
Waist Hip Ratio (WHR)	10.1	45.2	69.6	-6.8	6.8	5.8	6.9	7.2	6.3	-6.8	5.6	3.3	6.1	6.1	6.5	6.3	6.5	6.9	6.7	8.2	6.3	6.9	6.8	8.3	-8.1	-7.6
Intelligence (Savage-Jansen 2018)	10.0	30.8	88.7	0.2	7.4	4.1	6.0	7.3	8.3	-4.1	4.6	5.3	3.8	4.3	3.9	9.4	6.7	4.4	7.8	6.9	4.0	4.4	5.7	4.5	-2.4	-3.3
Qualifications: None of the above	9.7	20.9	39.9	1.4	-5.8	-4.0	-4.9	-5.6	-4.8	3.9	-4.5	-4.5	-4.2	-4.0	-3.7	-6.3	-5.3	-4.0	-5.9	-5.5	-4.3	-4.0	-4.8	-4.2	3.3	3.6
Overall health rating	9.3	20.0	37.9	-0.2	-5.7	-4.3	-4.8	-5.4	-5.3	3.8	-4.9	-5.4	-4.0	-4.1	-3.8	-6.2	-5.4	-3.8	-6.0	-4.5	-4.1	-3.7	-4.7	-3.2	2.0	3.2
Age at first live birth	9.1	16.1	26.2	-1.5	5.1	3.8	4.1	5.1	4.0	-3.6	4.2	4.7	3.4	3.8	3.6	5.0	4.7	3.6	5.1	4.4	3.5	3.6	4.2	3.4	-2.8	-3.3
Age at last live birth	9.0	13.0	22.5	-0.4	4.7	3.2	3.9	4.6	4.0	-3.1	3.8	4.7	2.9	3.3	3.2	4.6	4.2	3.2	4.7	3.7	2.7	3.3	3.9	2.9	-1.9	-2.8
Pack years of smoking	9.0	13.3	17.7	2.8	-4.2	-3.6	-3.6	-4.1	-2.4	3.7	-3.6	-2.8	-3.3	-3.6	-3.7	-3.5	-3.9	-3.7	-4.0	-3.9	-4.0	-3.8	-3.8	-3.7	3.7	3.6
Irritability	8.9	15.0	20.7	3.0	-4.2	-4.3	-3.8	-3.7	-1.7	4.3	-4.5	-3.9	-4.0	-4.3	-4.3	-2.5	-4.1	-4.1	-3.7	-3.5	-4.5	-4.1	-4.1	-3.7	3.8	4.0
Impedance of whole body	8.9	45.5	58.5	-3.3	7.7	6.5	7.1	7.5	6.1	-6.7	7.2	7.4	6.0	6.6	6.7	6.4	7.1	6.8	7.5	7.2	6.3	6.8	7.5	6.9	-6.0	-6.7
Impedance of arm (right)	8.7	40.8	58.2	-2.8	7.6	5.9	6.6	7.3	5.5	-6.1	6.7	7.4	5.6	6.1	6.2	6.4	6.8	6.3	7.4	7.0	5.9	6.4	7.1	6.4	-5.7	-6.1
Number of operations (self-reported)	8.7	12.8	19.5	1.4	-4.0	-3.6	-3.9	-3.8	-3.1	3.5	-3.9	-4.4	-3.9	-3.6	-3.5	-3.4	-3.8	-3.6	-4.1	-3.4	-3.5	-3.6	-3.9	-3.3	2.6	3.6
Had major operations	8.5	9.9	13.8	1.6	-3.7	-3.2	-3.4	-3.5	-3.0	3.0	-3.4	-3.4	-3.6	-3.2	-3.1	-3.2	-3.5	-3.2	-3.7	-2.7	-2.8	-3.3	-3.5	-2.6	2.0	3.0
Pain experienced in last month	8.3	13.9	23.4	-0.6	4.8	3.7	4.0	4.5	4.0	-3.4	4.0	3.4	3.6	3.7	3.4	4.8	4.6	3.6	4.8	3.6	3.4	3.5	4.0	2.8	-1.7	-2.9
Heel bone mineral density (BMD) T-score, automated (right)	8.2	18.8	29.1	-4.8	3.1	4.7	4.2	3.2	1.6	-5.0	4.8	3.8	5.4	4.8	5.0	1.2	3.6	5.0	2.9	3.3	5.3	5.0	4.5	4.7	-4.8	-5.4
Mood swings	8.2	14.9	26.7	1.0	-5.2	-3.9	-4.0	-4.5	-4.0	3.6	-4.2	-3.5	-3.2	-3.9	-3.6	-4.8	-4.7	-3.6	-4.8	-4.0	-4.1	-3.5	-4.1	-3.0	2.2	2.8
Current tobacco smoking	8.1	13.2	16.2	3.0	-4.0	-3.7	-3.9	-4.0	-3.4	3.7	-3.6	-2.8	-3.5	-3.7	-3.4	-3.8	-4.0	-3.5	-3.9	-4.0	-3.6	-3.5	-3.5	-3.8	3.3	3.7
Neck or shoulder pain in last month	8.1	11.6	17.8	1.1	-4.2	-3.7	-3.5	-4.0	-2.8	3.3	-3.8	-3.6	-3.7	-3.6	-3.5	-3.6	-4.1	-3.5	-4.1	-2.6	-3.5	-3.5	-3.7	-2.3	1.5	2.9
Financial situation satisfaction	8.1	10.1	18.3	0.7	-4.3	-3.1	-3.1	-3.8	-3.0	2.8	-3.3	-3.8	-2.6	-3.0	-3.0	-3.9	-3.8	-3.1	-4.2	-2.9	-3.4	-3.1	-3.4	-2.3	1.6	2.3
Age at First Birth	7.7	11.2	23.4	0.5	4.7	3.1	3.4	4.4	4.7	-2.6	3.4	3.9	2.6	3.0	2.8	4.8	4.1	2.8	4.5	3.3	2.5	2.8	3.6	1.9	-1.1	-2.0
Medication: Co-codamol	7.7	8.9	14.5	1.5	-3.6	-2.7	-3.3	-3.5	-3.3	2.7	-2.9	-2.5	-2.6	-2.8	-2.5	-3.8	-3.4	-2.6	-3.5	-3.8	-2.5	-2.6	-3.0	-3.1	2.7	2.5
Qualifications: A levels/AS levels or equivalent	7.3	16.2	56.1	1.8	5.8	3.0	4.3	5.5	5.9	-2.5	3.5	4.2	2.6	2.9	2.5	7.5	5.1	2.8	6.2	4.3	2.5	2.8	4.0	2.1	-0.4	-1.6
Loneliness, isolation	7.3	10.1	17.3	1.0	-4.2	-3.2	-3.3	-3.8	-3.3	2.9	-3.4	-2.6	-3.0	-3.1	-3.0	-4.0	-3.9	-3.0	-4.1	-3.1	-3.1	-2.9	-3.3	-2.4	1.8	2.6
Smoking status: Current	7.3	11.5	14.4	3.0	-3.8	-3.5	-3.6	-3.7	-3.3	3.5	-3.3	-2.3	-3.2	-3.5	-3.2	-3.7	-3.8	-3.2	-3.7	-3.8	-3.4	-3.2	-3.2	-3.5	3.0	3.4
Father’s age at death	7.2	9.7	20.3	-1.3	4.0	2.9	3.3	3.7	3.4	-2.8	3.0	3.1	2.3	2.8	2.6	4.5	3.7	2.4	4.0	3.9	2.8	2.5	3.0	2.8	-2.4	-2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	7.2	11.0	17.2	1.0	-3.4	-3.9	-3.6	-3.3	-2.7	3.5	-4.1	-3.7	-3.4	-3.6	-3.5	-2.8	-3.6	-3.3	-3.5	-3.0	-3.9	-3.3	-3.5	-3.0	2.1	3.1
Ever smoked	7.1	12.5	16.9	1.3	-3.6	-3.9	-3.9	-3.7	-2.7	3.7	-4.1	-4.0	-4.1	-3.9	-3.8	-3.1	-3.8	-3.7	-3.7	-2.7	-4.0	-3.7	-3.9	-2.9	2.0	3.4
Prostate Cancer	6.9	9.7	15.3	1.2	-3.9	-2.9	-3.4	-3.7	-3.2	2.7	-3.0	-3.5	-3.2	-2.9	-2.8	-3.9	-3.5	-2.9	-3.9	-3.4	-2.3	-2.9	-3.4	-2.7	2.3	2.5
Qualifications: O levels/GCSEs or equivalent	6.7	10.7	22.1	-0.5	4.3	3.1	3.6	4.1	3.5	-2.9	3.3	3.0	2.7	3.0	2.9	4.7	3.9	3.1	4.4	3.5	2.9	3.1	3.5	2.6	-1.6	-2.4
Diverticular disease/diverticulitis (self-reported)	6.5	7.7	9.3	2.4	-2.8	-3.0	-2.9	-2.8	-2.0	3.0	-2.8	-1.8	-2.9	-3.0	-3.0	-2.4	-3.0	-2.9	-2.8	-2.8	-2.8	-2.9	-2.8	-2.9	2.8	3.1
Lung cancer (father)	6.5	7.6	12.2	2.4	-3.5	-2.8	-2.8	-3.4	-2.7	2.6	-2.6	-1.1	-2.7	-2.8	-2.6	-3.4	-3.3	-2.7	-3.3	-2.9	-2.8	-2.7	-2.7	-2.4	1.9	2.4
Heel bone mineral density (BMD) T-score, automated (left)	6.3	14.2	24.1	-4.5	2.5	4.1	3.7	2.6	0.9	-4.4	4.1	3.1	4.9	4.3	4.4	0.7	3.0	4.4	2.3	2.7	4.6	4.4	3.8	4.1	-4.2	-4.8
Neuroticism	6.1	14.8	22.9	2.0	-4.8	-4.2	-3.9	-4.3	-3.1	3.9	-4.3	-3.0	-3.9	-4.2	-3.9	-4.1	-4.5	-3.7	-4.4	-3.9	-4.3	-3.7	-4.1	-3.2	2.6	3.2
Chronotype (morning person)	6.0	13.9	25.5	-1.9	4.0	4.0	4.1	3.9	2.8	-3.8	4.2	3.7	5.0	4.0	3.6	3.5	4.1	3.8	3.9	3.6	3.4	3.8	4.0	3.5	-2.7	-3.7
Taking other prescription medications	6.0	9.3	20.4	0.2	-3.8	-2.8	-3.4	-3.6	-3.5	2.6	-3.4	-4.5	-2.6	-2.9	-2.6	-4.0	-3.5	-2.6	-4.0	-2.9	-2.3	-2.7	-3.3	-2.2	1.3	2.2
Forced expiratory volume in 1-second (FEV1)	6.0	20.4	34.5	-1.3	5.3	4.1	4.9	5.3	4.5	-4.2	4.6	5.3	3.6	4.0	4.0	5.9	5.1	4.0	5.5	5.2	4.6	4.0	4.8	4.3	-3.5	-3.6
Relative age voice broke	5.9	9.1	14.6	2.2	-2.4	-3.7	-3.2	-2.3	-1.9	3.5	-3.8	-3.0	-3.8	-3.6	-3.6	-1.2	-2.8	-3.4	-2.3	-1.8	-3.5	-3.4	-3.2	-2.8	2.1	3.6
Tense / ‘highly strung’	5.9	9.8	14.4	2.9	-3.2	-3.5	-3.1	-3.1	-2.0	3.4	-3.4	-2.2	-3.2	-3.4	-3.4	-2.5	-3.3	-3.3	-3.1	-3.2	-3.8	-3.2	-3.2	-3.2	3.0	3.1
Seen a psychiatrist for nerves, anxiety, tension or depression	5.8	7.5	12.6	0.8	-2.8	-3.3	-2.9	-2.7	-2.3	3.0	-3.5	-2.7	-2.9	-3.1	-3.1	-2.4	-3.0	-2.7	-2.8	-2.2	-3.5	-2.8	-2.9	-2.1	1.3	2.5
Heel T-Score	5.6	44.7	83.4	-8.0	4.7	7.5	6.4	4.7	0.5	-7.7	7.4	5.8	9.1	7.5	7.4	1.2	5.4	7.3	4.2	5.4	7.5	7.4	6.7	7.5	-8.2	-8.5
Forced expiratory volume in 1-second (FEV1), Best measure	5.5	17.4	29.9	-0.8	5.0	3.8	4.6	5.0	4.4	-3.9	4.3	4.8	3.3	3.8	3.6	5.5	4.8	3.5	5.1	4.8	3.9	3.7	4.4	3.9	-3.2	-3.2
Ever highly irritable/argumentative for 2 days	5.4	6.5	11.0	0.0	-2.9	-2.5	-2.6	-2.9	-2.1	2.4	-2.9	-3.3	-2.3	-2.4	-2.3	-2.8	-2.9	-2.2	-3.0	-2.9	-3.1	-2.1	-2.7	-2.4	1.9	2.2
Stomach or abdominal pain in last month	5.3	6.6	9.1	1.4	-3.0	-2.6	-2.6	-2.9	-2.0	2.6	-2.5	-1.4	-2.7	-2.7	-2.5	-2.8	-3.0	-2.6	-2.9	-2.7	-2.8	-2.5	-2.7	-2.5	2.2	2.4
Blood Eosinophil Count	5.2	40.3	103.9	-9.0	6.3	5.5	5.5	6.0	2.5	-6.7	4.4	0.0	5.7	5.8	6.2	4.5	5.7	6.5	5.2	8.2	6.5	6.5	5.8	8.4	-10.2	-7.2
Diabetes diagnosed by doctor	5.2	8.6	16.6	-4.1	2.1	3.2	3.0	2.5	2.2	-3.4	2.6	-0.1	3.6	3.2	3.2	1.9	2.7	3.3	2.1	2.8	3.0	3.2	2.7	3.3	-3.2	-3.6
Neuroticism score	5.1	10.7	16.8	1.4	-4.1	-3.8	-3.3	-3.6	-2.7	3.3	-3.9	-2.8	-3.3	-3.6	-3.2	-3.5	-3.9	-3.1	-3.8	-3.1	-3.9	-3.0	-3.4	-2.5	1.8	2.6
Depression (self-reported)	5.1	6.1	8.6	2.0	-2.5	-2.8	-2.5	-2.4	-2.1	2.8	-2.8	-1.6	-2.9	-2.8	-2.8	-1.9	-2.5	-2.5	-2.3	-2.2	-2.5	-2.7	-2.5	-2.4	2.0	2.9
Neuroticism (2016)	5.0	7.2	13.5	0.5	-3.7	-2.9	-2.8	-3.3	-2.8	2.6	-3.0	-1.6	-2.6	-2.8	-2.6	-3.5	-3.2	-2.6	-3.2	-2.5	-2.9	-2.6	-2.9	-1.7	1.2	1.9
Number of incorrect matches in round	4.9	8.1	12.1	1.8	-2.9	-2.6	-3.0	-3.1	-3.2	2.9	-2.6	-1.9	-2.0	-2.6	-3.0	-3.1	-2.9	-2.8	-3.1	-3.5	-2.9	-2.8	-2.9	-3.2	3.0	2.6
Diabetes (self-reported)	4.9	7.5	16.6	-4.1	1.8	3.1	2.8	2.3	1.9	-3.3	2.4	-0.2	3.3	3.1	3.1	1.5	2.4	3.1	1.8	2.5	2.7	3.0	2.4	3.1	-3.0	-3.5
Serious illness, injury or assault of a close relative in last 2 years	4.9	5.6	8.2	1.8	-1.8	-2.7	-2.6	-2.0	-2.1	2.7	-2.9	-2.4	-2.6	-2.7	-2.8	-1.0	-2.2	-2.6	-1.9	-1.8	-2.3	-2.7	-2.6	-2.4	2.2	2.8
Past tobacco smoking	4.8	8.8	16.8	-0.3	3.2	3.0	3.2	3.3	2.0	-2.9	3.4	4.1	3.5	3.1	3.1	2.8	3.2	3.2	3.4	2.0	3.3	3.2	3.5	2.1	-1.3	-2.6
Neuroticism (Nagel 2018)	4.7	11.2	15.9	1.7	-3.9	-3.8	-3.4	-3.7	-2.9	3.5	-4.0	-2.6	-3.4	-3.6	-3.4	-3.5	-3.9	-3.0	-3.7	-3.3	-3.8	-3.3	-3.6	-2.8	2.3	2.8
Verbal and Numeric Reasoning (VNR)	4.7	11.2	36.0	1.7	4.5	2.3	3.5	4.4	5.2	-2.1	2.8	4.1	1.9	2.3	2.0	6.0	4.1	2.3	4.9	4.0	2.3	2.3	3.5	2.1	-0.9	-1.3
Osteoporosis (self-reported)	4.7	5.9	9.1	2.2	-1.6	-2.4	-2.6	-1.8	-2.0	2.7	-2.5	-2.6	-2.7	-2.6	-2.8	-0.9	-1.8	-2.9	-1.6	-1.9	-2.8	-2.9	-2.8	-2.8	2.3	3.0
Crohns Disease (2017)	4.4	9.7	53.3	1.6	4.6	1.4	2.8	4.5	6.1	-1.3	1.4	-0.1	1.3	1.4	0.8	7.3	4.0	1.0	4.8	4.7	0.0	1.0	2.0	1.8	-0.8	-0.4
Had other major operations	4.3	5.3	7.9	1.9	-2.0	-2.8	-2.4	-2.0	-1.1	2.6	-2.8	-2.6	-2.8	-2.7	-2.6	-1.0	-2.2	-2.5	-1.9	-1.8	-2.4	-2.4	-2.3	-2.3	2.0	2.7
Illnesses of father: High blood pressure	4.3	5.3	7.1	-2.3	2.2	2.2	2.5	2.5	2.3	-2.3	2.1	1.3	2.5	2.3	2.3	2.2	2.3	2.6	2.3	2.1	2.6	2.7	2.5	2.3	-1.3	-2.6
Exposure to tobacco smoke outside home	4.2	5.5	10.3	0.8	-2.8	-2.0	-2.6	-2.7	-2.9	2.0	-2.4	-3.2	-2.2	-2.1	-2.0	-2.9	-2.6	-2.2	-2.9	-2.4	-1.8	-2.2	-2.6	-2.1	1.4	2.1
Mother’s age at death	4.2	5.3	12.0	-1.1	2.6	2.0	2.3	2.5	1.5	-2.1	2.4	3.5	2.0	2.1	2.2	2.2	2.3	2.3	2.7	2.3	2.2	2.3	2.6	2.3	-2.2	-2.2
Medication for pain relief, constipation, heartburn	4.1	7.0	12.2	-0.2	3.5	2.7	2.7	3.1	1.3	-2.4	2.9	3.2	2.7	2.6	2.7	3.0	3.1	2.6	3.3	2.3	3.0	2.5	2.9	1.9	-1.7	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.1	8.7	21.8	-0.0	3.1	3.1	3.2	3.1	2.6	-2.8	3.6	4.7	3.1	3.0	2.9	2.9	3.3	2.7	3.3	2.4	3.2	2.8	3.3	2.2	-1.4	-2.3
Frequency of depressed mood in last 2 weeks	4.0	5.5	7.2	1.7	-2.6	-2.5	-2.5	-2.4	-2.4	2.5	-2.5	-1.3	-2.5	-2.5	-2.2	-2.4	-2.6	-2.3	-2.5	-2.4	-2.7	-2.3	-2.4	-2.3	1.9	2.4
Osteoarthritis (self-reported)	4.0	5.2	8.2	1.1	-2.8	-2.1	-2.4	-2.8	-2.8	2.1	-2.2	-2.1	-2.1	-2.1	-2.0	-2.9	-2.6	-1.9	-2.7	-2.9	-1.6	-2.0	-2.3	-2.2	2.0	1.9
Guilty feelings	4.0	6.0	10.8	0.1	-3.1	-2.5	-2.8	-2.9	-3.2	2.1	-2.8	-2.8	-2.4	-2.4	-2.1	-3.3	-3.0	-2.1	-3.1	-2.2	-2.2	-2.1	-2.7	-1.6	0.8	1.7
HbA1C	3.9	4.3	6.8	0.0	2.1	1.6	2.3	2.3	2.5	-2.0	1.8	2.3	1.6	1.8	1.9	2.6	2.2	1.7	2.4	2.6	1.7	1.8	2.1	2.4	-2.4	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.9	4.6	8.1	1.0	-2.9	-2.4	-2.1	-2.4	-0.7	2.1	-2.6	-2.1	-2.2	-2.4	-2.2	-2.2	-2.6	-2.2	-2.6	-1.6	-2.4	-2.2	-2.4	-1.5	1.1	1.9
Impedance of leg (left)	3.8	18.7	26.2	-1.5	4.7	3.9	4.7	4.7	5.0	-4.2	4.7	5.1	3.6	4.1	4.1	4.2	4.4	4.3	4.8	4.6	3.9	4.4	4.9	4.5	-3.5	-4.3
Relative age of first facial hair	3.7	7.6	18.1	0.7	-2.1	-3.4	-3.0	-2.1	-1.9	3.1	-4.0	-4.2	-3.4	-3.3	-3.1	-1.1	-2.5	-2.9	-2.2	-1.5	-2.9	-3.0	-3.2	-2.1	1.4	3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	3.7	4.9	10.0	0.7	-3.0	-2.1	-2.3	-2.7	-3.1	1.8	-2.2	-1.8	-2.1	-2.1	-1.8	-3.2	-2.7	-2.0	-2.9	-2.1	-2.2	-2.0	-2.4	-1.4	0.6	1.5
Qualifications: CSEs or equivalent	3.7	4.9	8.6	0.8	-2.7	-2.1	-2.4	-2.5	-2.7	2.0	-2.3	-2.1	-1.8	-2.0	-1.7	-2.9	-2.6	-1.8	-2.7	-2.9	-1.5	-1.8	-2.2	-2.2	2.1	1.7
Exposure to tobacco smoke at home	3.7	4.1	16.1	-0.7	-2.4	-1.7	-2.1	-2.3	-1.5	1.6	-2.3	-4.0	-1.8	-1.6	-1.5	-2.5	-2.1	-1.6	-2.6	-2.1	-1.8	-1.7	-2.4	-1.5	1.1	1.2
Alcohol drinker status: Never	3.7	4.5	6.6	-0.4	2.2	2.4	2.5	2.0	2.0	-2.2	2.6	2.5	2.4	2.4	2.4	1.7	2.2	2.3	2.1	1.3	2.3	2.4	2.5	1.5	-0.7	-1.9
Noisy workplace	3.6	4.4	6.7	0.9	-2.6	-1.9	-2.1	-2.4	-2.4	1.9	-2.0	-2.0	-2.0	-2.0	-1.9	-2.5	-2.3	-2.0	-2.5	-2.5	-2.2	-2.0	-2.2	-2.0	1.7	1.9
Health satisfaction	3.6	4.7	14.2	-0.7	-2.9	-2.0	-2.1	-2.4	-1.7	1.7	-2.4	-3.8	-1.6	-1.9	-1.9	-2.8	-2.6	-1.9	-3.0	-1.7	-2.5	-1.8	-2.3	-1.2	0.4	1.2
Forced vital capacity (FVC), Best measure	3.5	12.9	22.3	-1.3	4.4	3.1	3.8	4.3	3.5	-3.3	3.6	4.0	2.8	3.1	3.0	4.7	4.0	2.9	4.4	4.6	3.1	3.1	3.6	3.6	-3.4	-2.9
Knee pain experienced in last month	3.5	5.4	9.0	-0.3	-3.0	-2.4	-2.4	-2.9	-2.3	2.1	-2.5	-2.4	-2.5	-2.3	-2.3	-2.8	-2.8	-2.3	-3.0	-2.0	-2.0	-2.2	-2.6	-1.6	1.0	1.9
Unable to work because of sickness or disability	3.5	4.6	6.3	2.2	-2.1	-2.2	-2.1	-2.1	-1.8	2.3	-2.3	-1.0	-1.9	-2.2	-2.2	-1.8	-2.2	-2.0	-2.0	-2.4	-2.5	-2.1	-2.0	-2.4	2.4	2.3
Forced vital capacity (FVC)	3.4	13.1	22.5	-1.5	4.4	3.1	3.9	4.3	3.5	-3.3	3.5	4.2	2.9	3.1	3.0	4.7	4.0	3.0	4.4	4.6	3.3	3.2	3.7	3.7	-3.4	-2.9
Impedance of leg (right)	3.3	15.9	22.0	-1.3	4.5	3.6	4.4	4.4	4.6	-3.8	4.3	4.7	3.3	3.8	3.9	3.9	4.1	4.0	4.5	4.2	3.4	4.1	4.5	4.0	-3.1	-3.9
Body mass index (BMI)	3.3	14.0	44.9	-1.8	-5.5	-2.5	-3.9	-5.1	-5.1	2.3	-3.4	-4.9	-1.5	-2.4	-2.1	-6.7	-4.5	-2.2	-5.7	-4.9	-2.5	-2.3	-3.6	-2.8	1.6	1.7
Wheeze or whistling in the chest in last year	3.3	5.8	17.6	-2.7	-2.9	-2.1	-2.6	-2.8	-3.5	1.5	-2.7	-4.2	-1.2	-1.8	-1.7	-3.8	-2.9	-1.5	-3.4	-1.6	-1.9	-1.5	-2.5	-0.6	-1.0	0.7
Townsend deprivation index at recruitment	3.2	4.5	7.4	2.7	-2.7	-2.2	-1.9	-2.4	-0.6	2.2	-1.9	-0.8	-1.9	-2.1	-2.2	-2.1	-2.5	-2.0	-2.4	-2.3	-2.2	-2.1	-1.8	-2.1	2.4	2.2
Number of self-reported non-cancer illnesses	3.2	5.5	10.3	0.7	-2.5	-2.5	-2.5	-2.5	-2.1	2.3	-2.9	-3.2	-2.4	-2.4	-2.4	-2.1	-2.5	-2.2	-2.6	-2.1	-2.3	-2.3	-2.5	-2.0	1.7	2.2
Triglycerides	3.1	5.1	7.7	-1.9	1.8	2.3	2.4	2.0	1.1	-2.5	2.4	2.1	2.3	2.4	2.5	1.3	2.0	2.5	1.9	2.2	2.8	2.5	2.5	2.6	-2.3	-2.7
Vitamin and mineral supplements	3.1	4.2	6.8	-2.0	1.8	2.1	2.1	1.9	1.1	-2.2	2.1	1.8	2.6	2.2	2.2	1.3	2.0	2.3	1.8	1.9	2.1	2.2	2.1	2.1	-2.2	-2.4
Family relationship satisfaction	3.1	3.8	9.4	0.8	-1.9	-2.2	-2.1	-1.8	-1.7	2.1	-2.3	-3.1	-1.9	-2.1	-2.2	-1.3	-2.1	-2.1	-2.1	-1.4	-1.9	-2.1	-2.2	-1.6	1.1	1.9
Ever taken oral contraceptive pill	3.1	3.5	5.2	0.9	-1.9	-2.2	-2.1	-1.8	-1.7	2.0	-2.3	-2.0	-2.0	-2.1	-2.1	-1.4	-2.0	-1.9	-1.8	-1.4	-2.0	-2.0	-2.1	-1.5	1.0	1.8
Systolic blood pressure, automated reading	3.0	8.6	15.0	1.3	-3.9	-2.9	-2.9	-3.6	-2.3	2.8	-3.3	-2.8	-2.2	-2.9	-2.6	-3.6	-3.5	-2.4	-3.7	-3.7	-2.1	-2.5	-2.9	-2.8	3.0	2.1
Mouth/teeth dental problems: Dentures	3.0	5.1	12.7	-1.0	-3.1	-1.9	-2.4	-2.9	-2.8	1.7	-2.4	-2.7	-1.8	-1.9	-1.6	-3.6	-2.7	-1.7	-3.2	-2.4	-2.2	-1.8	-2.4	-1.4	0.5	1.3
Depression (Nagel 2018)	2.9	4.3	6.5	1.1	-2.5	-2.3	-2.1	-2.3	-1.8	2.1	-2.4	-1.1	-2.4	-2.3	-2.0	-2.2	-2.4	-2.1	-2.4	-1.8	-2.5	-2.1	-2.2	-1.5	1.0	1.8
Maternal smoking around birth	2.9	4.2	8.1	0.5	-2.9	-1.9	-1.9	-2.6	-1.2	1.8	-1.9	-2.7	-2.0	-2.0	-1.9	-2.4	-2.4	-2.2	-2.6	-1.7	-2.5	-2.3	-2.5	-1.4	0.7	1.4
Tinnitus: Yes, but not now, but have in the past	2.9	3.1	10.2	-0.1	-2.5	-1.4	-1.9	-2.5	-2.9	1.3	-1.4	-0.8	-1.4	-1.4	-1.4	-3.2	-2.2	-1.4	-2.6	-1.7	-1.1	-1.5	-1.8	-0.9	0.3	1.0
Number of treatments/medications taken	2.8	5.1	16.0	-1.6	-3.1	-1.7	-2.4	-2.9	-2.6	1.5	-2.4	-4.0	-1.5	-1.7	-1.6	-3.5	-2.7	-1.6	-3.2	-2.1	-1.6	-1.6	-2.4	-1.2	0.4	1.0
Multivitamins +/- minerals	2.8	3.6	6.1	1.3	-2.1	-1.7	-2.1	-2.1	-1.3	1.8	-1.7	-1.4	-2.5	-1.8	-1.9	-1.9	-2.0	-2.1	-2.1	-1.7	-1.7	-2.1	-2.1	-1.8	1.6	2.1
Diabetes (father)	2.7	3.3	6.0	-1.5	1.6	2.0	2.1	1.7	2.4	-2.0	1.9	0.7	1.7	2.1	2.1	1.5	1.8	2.0	1.6	1.6	1.8	2.1	2.0	1.7	-1.2	-1.7
Worry too long after embarrassment	2.7	4.5	10.4	-1.5	2.5	1.3	2.1	2.7	3.0	-1.6	1.2	1.3	1.8	1.4	1.6	3.2	2.3	1.9	2.8	2.9	1.4	1.9	2.0	2.4	-2.0	-2.1
Medication: Omeprazole	2.6	3.1	5.8	1.0	-2.4	-1.5	-1.8	-2.3	-1.7	1.5	-1.6	-1.6	-1.8	-1.6	-1.5	-2.4	-2.0	-1.7	-2.4	-1.9	-1.2	-1.8	-2.0	-1.5	1.2	1.6
Blood Red Count	2.5	24.4	41.7	-4.2	3.5	5.2	5.4	3.9	3.9	-5.7	5.4	4.2	5.7	5.5	5.9	1.7	4.1	6.0	3.5	3.5	5.5	6.0	5.6	5.4	-4.6	-6.5
Lung FVC	2.5	12.6	26.3	0.8	4.2	3.5	4.0	4.1	3.8	-3.1	4.1	5.1	3.3	3.3	3.1	4.8	4.2	3.0	4.6	3.2	3.6	3.0	3.8	2.3	-1.0	-2.2
Medication: Metformin	2.5	3.5	7.4	-2.7	1.2	2.2	1.9	1.4	1.3	-2.3	1.8	-0.4	2.4	2.2	2.0	0.8	1.6	1.9	1.0	1.8	1.9	1.9	1.5	2.2	-2.2	-2.3
Leg pain on walking	2.5	3.2	7.9	-1.1	-2.5	-1.5	-1.9	-2.2	-2.6	1.3	-1.7	-2.4	-1.4	-1.5	-1.2	-2.8	-2.3	-1.2	-2.5	-2.0	-0.3	-1.2	-1.8	-1.1	0.7	0.8
Heart disease (siblings)	2.5	3.1	5.0	1.5	-2.2	-1.7	-1.6	-2.1	-1.1	1.8	-1.6	-1.1	-1.5	-1.7	-1.9	-1.8	-2.0	-1.7	-2.0	-2.1	-1.7	-1.7	-1.6	-1.8	2.1	1.7
BMI	2.4	14.2	48.3	-2.8	-5.3	-2.2	-3.9	-5.0	-5.4	2.1	-3.3	-5.5	-1.1	-2.1	-1.9	-7.0	-4.4	-2.0	-5.8	-4.8	-2.5	-2.1	-3.6	-2.6	1.1	1.4
Back pain experienced in last month	2.4	3.5	7.4	-0.3	-2.5	-1.8	-2.0	-2.4	-2.5	1.6	-1.9	-1.6	-1.7	-1.9	-1.7	-2.7	-2.4	-1.8	-2.5	-1.4	-1.8	-1.7	-2.1	-0.9	0.1	1.1
Commuting to job workplace: Cycle	2.4	2.8	5.8	-0.6	1.8	1.7	1.7	2.0	1.0	-1.7	1.7	1.1	1.7	1.6	1.4	1.9	1.9	1.3	1.9	2.4	1.7	1.3	1.6	1.9	-2.3	-1.5
Medication: Omeprazole (e.g. Zanprol)	2.4	2.9	4.5	1.0	-2.1	-1.4	-1.8	-2.1	-1.4	1.5	-1.5	-1.4	-1.8	-1.6	-1.6	-2.0	-1.8	-1.7	-2.1	-1.8	-1.4	-1.8	-1.9	-1.6	1.4	1.7
Breast Cancer	2.3	5.5	13.5	0.5	3.0	2.2	2.5	3.1	3.0	-1.8	2.3	2.2	2.2	2.2	2.1	3.7	3.0	2.1	3.4	1.8	2.0	2.1	2.6	1.0	-0.0	-1.4
Crohns Disease (2012)	2.3	3.7	24.4	2.9	2.3	-0.2	1.0	2.3	4.9	0.4	-0.1	-0.3	-0.4	-0.3	-0.6	4.6	1.8	-0.5	2.6	2.1	-1.6	-0.4	0.5	-0.1	1.0	1.0
Lung FEV1/FVC ratio	2.3	11.8	22.6	0.4	3.5	3.2	3.8	3.7	3.9	-3.2	3.7	4.8	2.3	3.2	3.4	3.8	3.7	3.3	4.0	3.3	4.0	3.3	4.1	3.0	-2.4	-2.6
Alcohol usually taken with meals	2.3	3.7	5.8	-0.9	2.3	2.0	2.1	2.1	1.8	-1.9	2.3	2.0	1.7	2.1	1.9	2.1	2.2	1.9	2.4	1.8	2.0	1.8	2.0	1.6	-1.1	-1.6
Fluid intelligence score	2.3	4.9	18.8	2.3	3.0	1.1	2.2	2.8	3.8	-0.9	1.7	3.4	0.6	1.1	0.8	4.3	2.6	1.0	3.3	2.4	1.1	1.1	2.2	0.8	0.2	-0.1
Number of children fathered	2.3	2.6	4.2	1.0	-2.0	-1.4	-1.7	-1.9	-1.9	1.5	-1.5	-1.3	-1.7	-1.5	-1.3	-2.0	-1.8	-1.6	-1.9	-1.9	-1.4	-1.6	-1.7	-1.6	1.1	1.5
Illnesses of siblings: Diabetes	2.3	2.9	4.0	1.5	-2.0	-1.7	-1.6	-1.8	-0.7	1.8	-1.7	-1.4	-1.7	-1.7	-1.7	-1.3	-1.7	-1.8	-1.7	-2.0	-1.6	-1.8	-1.7	-1.9	1.9	1.7
High cholesterol (Self-reported)	2.3	4.1	7.1	-1.5	1.9	2.5	2.2	1.8	1.3	-2.3	2.3	1.7	2.7	2.5	2.3	1.4	2.1	2.2	1.7	1.5	2.2	2.2	2.2	1.7	-1.3	-2.2
Arm fat-free mass (left)	2.3	11.8	28.1	-1.9	-4.5	-3.3	-3.5	-4.0	-3.9	2.7	-4.0	-5.3	-2.6	-3.2	-3.2	-4.3	-4.2	-3.0	-4.7	-2.3	-3.2	-3.1	-3.9	-1.6	-0.1	2.0
Average weekly spirits intake	2.2	2.7	14.2	-1.5	-2.1	-0.7	-1.7	-2.2	-3.4	0.7	-0.9	-0.9	-0.8	-0.7	-0.4	-3.8	-2.0	-0.6	-2.5	-2.0	-0.6	-0.6	-1.2	-0.8	-0.2	0.5
Chronic bronchitis/emphysema (father)	2.2	2.6	5.0	-0.3	-1.5	-2.0	-2.0	-1.5	-1.1	1.7	-2.2	-2.1	-1.8	-1.9	-1.7	-1.4	-1.8	-1.5	-1.6	-1.2	-1.9	-1.5	-1.7	-1.2	0.5	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.2	2.6	6.0	-0.7	1.2	2.1	2.0	1.2	2.4	-1.8	1.9	1.5	1.7	2.0	1.7	1.3	1.8	1.6	1.5	1.1	1.6	1.5	1.5	1.4	-0.5	-1.6
Average weekly beer plus cider intake	2.2	3.1	11.4	-1.4	-2.2	-1.5	-2.0	-1.9	-2.7	1.1	-2.0	-3.4	-1.5	-1.4	-0.9	-2.6	-2.1	-1.1	-2.4	-1.3	-1.2	-1.1	-1.7	-0.7	-0.5	0.7
Hypothyroidism (self reported)	2.1	4.9	14.0	2.7	-2.1	-2.0	-2.0	-2.0	-0.9	2.4	-2.1	-2.1	-2.0	-2.1	-2.2	-1.2	-1.9	-2.0	-1.9	-2.8	-1.9	-2.1	-2.0	-2.9	3.7	2.4
Medication: Simvastatin	2.1	3.1	5.7	-2.2	1.6	2.1	1.8	1.6	1.1	-2.0	1.7	0.9	2.4	2.1	1.9	1.2	1.8	1.9	1.4	1.6	1.7	1.9	1.7	1.6	-1.5	-1.9
Leg fat percentage (right)	2.1	7.4	34.2	-2.2	-4.2	-1.4	-2.5	-3.9	-3.5	1.2	-2.0	-3.4	-0.5	-1.2	-0.9	-5.8	-3.4	-0.8	-4.4	-4.0	-1.6	-0.9	-2.1	-1.6	0.9	0.4
Age started oral contraceptive pill	2.1	2.6	6.6	-0.5	2.4	1.4	1.6	2.2	2.0	-1.3	1.5	1.2	0.9	1.3	1.1	2.6	2.0	1.3	2.3	2.1	1.6	1.2	1.6	1.4	-1.0	-1.0
Arm predicted mass (left)	2.1	10.4	26.4	-2.2	-4.2	-3.0	-3.3	-3.8	-3.8	2.4	-3.7	-5.1	-2.4	-2.9	-2.9	-4.2	-3.9	-2.7	-4.5	-2.1	-3.0	-2.8	-3.7	-1.4	-0.2	1.8
Illnesses of siblings	2.0	2.8	8.6	-1.9	1.8	1.5	1.4	1.6	0.2	-1.7	1.7	1.5	1.4	1.5	1.5	1.1	1.5	1.4	1.5	2.2	1.8	1.4	1.5	2.1	-2.9	-1.7
Pulse wave reflection index	2.0	2.5	10.0	0.6	-1.3	-1.2	-1.6	-1.4	-1.0	1.5	-1.7	-3.2	-1.9	-1.4	-1.6	-0.6	-1.1	-1.9	-1.4	-1.0	-1.6	-1.9	-2.0	-1.6	1.3	1.8
Leg fat mass (right)	2.0	7.8	33.8	-3.4	-4.2	-1.4	-2.6	-3.8	-3.9	1.0	-2.3	-4.1	-0.5	-1.3	-0.9	-5.8	-3.4	-0.9	-4.5	-3.2	-1.6	-1.0	-2.3	-0.9	-0.4	0.1
Number of full sisters	2.0	2.5	6.1	1.3	-1.7	-1.6	-1.2	-1.5	-0.1	1.6	-1.7	-1.4	-1.6	-1.5	-1.5	-1.0	-1.6	-1.4	-1.6	-2.0	-1.7	-1.4	-1.5	-1.8	2.5	1.6
Leg fat mass (left)	2.0	7.9	34.1	-3.3	-4.3	-1.4	-2.6	-3.8	-4.0	1.0	-2.3	-4.1	-0.5	-1.3	-0.9	-5.8	-3.4	-0.9	-4.5	-3.1	-1.6	-1.0	-2.4	-0.9	-0.5	0.1
Ovarian Cancer	1.9	2.5	4.1	2.0	-1.7	-1.5	-1.7	-1.7	-1.3	1.7	-1.4	-0.8	-1.3	-1.6	-1.6	-1.6	-1.6	-1.6	-1.6	-1.8	-1.0	-1.6	-1.5	-1.8	1.6	1.9
Type 2 Diabetes (T2D) (2018)	1.9	3.6	7.7	-2.8	1.1	2.1	1.9	1.4	1.1	-2.3	1.7	-0.5	2.3	2.1	2.2	0.8	1.6	2.1	1.0	1.7	2.2	2.1	1.7	2.2	-2.3	-2.6
Had menopause	1.9	2.3	7.3	-0.4	2.2	1.4	1.6	1.9	2.3	-1.2	1.3	0.5	1.1	1.4	1.1	2.7	2.1	1.1	2.2	1.7	1.2	1.1	1.3	0.9	-0.4	-0.7
Happiness	1.9	2.4	4.2	1.9	-1.3	-2.0	-1.2	-1.0	-0.1	1.8	-2.0	-1.8	-1.8	-1.9	-1.9	-0.1	-1.4	-1.7	-1.1	-0.7	-2.0	-1.7	-1.4	-1.2	1.3	1.6
Medication: Ibuprofen	1.9	2.3	4.8	-0.1	-2.2	-1.4	-1.5	-2.0	-1.1	1.3	-1.4	-1.8	-1.5	-1.3	-1.4	-1.9	-1.9	-1.4	-2.0	-1.4	-1.4	-1.4	-1.7	-1.1	0.9	1.2
Leg fat percentage (left)	1.9	6.8	32.1	-2.2	-4.1	-1.2	-2.4	-3.8	-3.4	1.1	-1.9	-3.2	-0.3	-1.1	-0.8	-5.7	-3.2	-0.7	-4.2	-3.8	-1.4	-0.8	-2.0	-1.4	0.6	0.2
Height	1.8	34.6	136.9	-10.0	6.1	3.5	4.8	5.8	3.0	-5.2	3.2	1.0	3.3	3.7	3.6	5.6	4.7	4.2	4.9	10.4	3.3	4.2	4.1	9.1	-11.7	-6.1
Financial difficulties in last 2 years	1.8	2.4	6.0	0.1	-2.4	-1.5	-1.4	-2.0	-1.1	1.3	-1.5	-1.1	-1.0	-1.3	-1.2	-2.4	-2.1	-1.1	-2.3	-2.0	-1.6	-1.1	-1.4	-1.2	1.2	1.0
Hip circumference	1.8	7.8	21.8	-1.3	-4.0	-2.1	-2.9	-3.7	-3.4	1.9	-2.7	-3.4	-1.7	-2.1	-1.9	-4.7	-3.4	-1.9	-4.2	-3.3	-2.4	-2.0	-2.8	-2.0	1.0	1.6
Arm fat-free mass (right)	1.8	9.1	26.5	-2.7	-3.9	-2.6	-3.0	-3.5	-3.6	2.1	-3.4	-5.2	-2.0	-2.6	-2.6	-3.9	-3.5	-2.5	-4.2	-1.6	-2.8	-2.6	-3.5	-0.9	-0.7	1.4
Emphysema/chronic bronchitis	1.8	2.0	3.9	0.5	-1.8	-1.8	-1.4	-1.5	-0.0	1.5	-2.0	-1.7	-1.7	-1.7	-1.6	-1.1	-1.6	-1.3	-1.4	-0.7	-1.9	-1.4	-1.5	-0.7	0.5	1.1
Arm predicted mass (right)	1.8	9.3	26.6	-2.8	-4.0	-2.7	-3.1	-3.5	-3.7	2.0	-3.4	-5.2	-2.1	-2.6	-2.6	-4.0	-3.6	-2.5	-4.3	-1.6	-2.8	-2.6	-3.5	-0.9	-0.9	1.4
Medication: Levothyroxine sodium	1.7	2.9	8.2	2.6	-1.5	-1.4	-1.4	-1.4	0.1	1.7	-1.5	-1.9	-1.7	-1.4	-1.6	-0.7	-1.2	-1.6	-1.3	-2.0	-1.4	-1.7	-1.6	-2.2	2.9	2.0
Medication: Cholesterol lowering	1.7	2.6	11.1	-3.3	0.8	1.9	1.4	0.9	0.3	-2.0	1.4	0.2	2.1	1.9	1.8	0.0	1.2	1.8	0.6	1.0	1.8	1.8	1.3	1.7	-1.7	-2.3
Standing height	1.7	16.9	65.8	-6.4	4.0	2.4	3.5	4.2	2.8	-3.7	2.4	0.8	2.3	2.5	2.6	4.1	3.3	2.9	3.5	7.3	2.2	2.9	2.9	6.4	-8.1	-4.3
Medication: Allopurinol	1.7	2.3	4.6	-2.1	1.2	1.7	1.4	1.2	0.4	-1.8	1.5	0.8	1.9	1.7	1.7	0.5	1.4	1.8	1.0	1.2	1.3	1.7	1.4	1.7	-1.9	-2.1
Ever had prostate specific antigen (PSA) test	1.7	2.0	4.7	-2.2	1.2	1.6	1.2	1.2	0.4	-1.6	1.4	1.2	1.2	1.5	1.5	0.6	1.3	1.3	1.1	1.4	1.5	1.4	1.2	1.7	-1.9	-1.7
Blood White Count	1.6	12.1	22.3	-0.1	-4.4	-3.6	-3.8	-4.1	-4.2	3.1	-3.9	-4.6	-2.4	-3.5	-3.1	-4.7	-4.4	-3.0	-4.6	-2.9	-3.4	-3.0	-3.6	-2.0	0.2	2.0
Sitting height	1.6	11.6	42.4	-6.5	2.5	2.5	2.7	2.8	0.6	-3.4	2.4	1.4	3.0	2.7	2.7	1.5	2.3	3.0	2.0	4.8	2.6	3.0	2.7	5.2	-6.5	-4.2
Glaucoma (self-reported)	1.6	1.9	4.3	-0.5	1.5	1.3	1.6	1.6	2.1	-1.1	1.2	1.2	1.9	1.3	1.1	2.0	1.5	1.2	1.7	1.3	1.0	1.2	1.4	0.9	-0.3	-1.1
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	8.7	-2.9	0.4	1.5	0.9	0.4	-1.2	-1.5	1.3	0.5	1.9	1.5	1.6	-0.8	0.6	1.6	0.2	0.4	1.3	1.5	1.1	1.4	-1.8	-1.9
Bipolar Disorder or Schizophrenia	1.5	3.7	7.1	2.3	-1.6	-2.3	-1.7	-1.4	0.2	2.3	-2.4	-1.7	-2.7	-2.3	-2.2	-0.3	-1.7	-2.2	-1.3	-1.1	-2.2	-2.2	-2.0	-1.8	2.0	2.3
Bipolar Disorder (2011)	1.5	1.4	3.2	1.6	-0.6	-1.2	-1.0	-0.6	0.2	1.4	-1.5	-1.0	-1.8	-1.3	-1.2	0.3	-0.8	-1.4	-0.5	-0.9	-1.2	-1.2	-1.2	-1.4	1.8	1.6
Trunk fat-free mass	1.5	8.8	24.0	-2.0	-3.4	-3.1	-3.0	-3.2	-3.1	2.4	-3.7	-4.9	-2.7	-3.1	-3.0	-2.9	-3.4	-2.9	-3.8	-1.0	-3.1	-2.9	-3.6	-0.9	-0.8	1.9
Time employed in main current job	1.5	1.8	3.3	0.0	1.3	1.8	1.3	1.3	1.0	-1.3	1.8	1.3	1.7	1.7	1.5	1.3	1.7	1.3	1.5	0.3	1.7	1.3	1.4	0.2	0.6	-0.8
Medication for cholesterol, blood pressure or diabetes	1.5	2.5	12.3	3.5	-0.5	-1.9	-1.3	-0.6	0.2	1.9	-1.3	0.4	-2.1	-2.0	-1.9	0.4	-1.0	-1.8	-0.3	-0.7	-1.6	-1.7	-1.0	-1.6	1.7	2.3
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	11.0	2.4	-1.3	-1.3	-1.4	-1.2	-0.1	1.8	-1.5	-2.1	-1.5	-1.4	-1.6	-0.3	-1.1	-1.5	-1.1	-2.1	-1.3	-1.7	-1.6	-2.4	3.3	2.0
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.7	2.6	-1.0	1.5	1.1	1.4	1.5	1.3	-1.2	1.2	1.1	1.4	1.2	1.0	1.4	1.4	1.3	1.5	1.6	1.1	1.2	1.4	1.5	-1.4	-1.4
Ever had bowel cancer screening	1.5	1.7	4.9	2.2	-0.4	-1.4	-1.0	-0.6	0.1	1.7	-1.2	0.6	-1.4	-1.4	-1.7	0.6	-0.6	-1.6	-0.1	-0.7	-1.3	-1.6	-1.0	-1.6	2.1	1.8
Qualifications: nursing, teaching	1.5	2.4	11.7	0.7	2.4	1.1	1.5	2.2	2.4	-0.7	1.0	0.4	1.1	1.0	0.7	3.4	2.1	0.8	2.5	1.9	0.8	0.7	1.2	0.6	0.0	-0.3
Bipolar Disorder (2018)	1.4	2.2	6.5	0.5	-1.3	-1.4	-1.6	-1.2	-1.4	1.5	-1.9	-2.5	-2.1	-1.6	-1.5	-0.8	-1.3	-1.6	-1.4	-0.8	-1.3	-1.6	-1.8	-1.1	0.9	1.5
High blood pressure (mother)	1.4	1.9	3.7	-0.5	1.6	1.6	1.7	1.5	1.9	-1.3	1.4	0.7	1.6	1.5	1.3	1.9	1.6	1.5	1.6	1.1	1.2	1.5	1.4	0.9	-0.1	-1.1
Arm fat mass (right)	1.4	5.9	28.2	-3.4	-3.6	-1.0	-2.2	-3.2	-3.9	0.6	-1.8	-3.3	-0.1	-0.9	-0.5	-5.3	-2.9	-0.5	-4.0	-2.7	-1.0	-0.6	-1.8	-0.6	-0.8	-0.2
Trunk predicted mass	1.4	8.2	22.8	-2.1	-3.3	-3.0	-2.9	-3.0	-2.9	2.3	-3.5	-4.8	-2.6	-2.9	-2.9	-2.8	-3.3	-2.7	-3.6	-0.9	-3.0	-2.8	-3.5	-0.8	-0.8	1.8
Whole body fat-free mass	1.4	7.8	22.0	-2.6	-3.4	-2.6	-2.8	-3.1	-3.5	2.0	-3.3	-4.7	-2.1	-2.6	-2.5	-3.3	-3.2	-2.4	-3.8	-1.1	-2.7	-2.5	-3.2	-0.7	-1.1	1.4
Whole body water mass	1.4	8.1	22.5	-2.6	-3.5	-2.7	-2.9	-3.2	-3.5	2.0	-3.4	-4.7	-2.2	-2.6	-2.6	-3.4	-3.3	-2.5	-3.8	-1.2	-2.7	-2.5	-3.3	-0.7	-1.0	1.4
Medication: Atorvastatin	1.4	1.8	3.9	-1.8	0.9	1.5	1.4	1.1	2.0	-1.5	1.2	0.2	1.4	1.5	1.4	1.0	1.3	1.4	1.0	1.0	1.5	1.3	1.2	1.3	-1.1	-1.5
Weight	1.3	6.3	21.3	-4.3	-3.5	-1.3	-2.2	-3.0	-3.7	0.7	-2.2	-4.2	-0.5	-1.2	-0.9	-4.6	-2.9	-0.9	-3.9	-1.5	-1.4	-1.0	-2.2	0.1	-1.9	-0.2
Illnesses of mother	1.3	1.6	4.4	2.1	-0.8	-1.2	-1.4	-1.0	-1.2	1.4	-1.0	-0.2	-1.5	-1.3	-1.3	-0.7	-1.0	-1.4	-0.9	-1.0	-1.1	-1.5	-1.1	-1.5	1.3	1.8
Commuting to job workplace: Car/motor vehicle	1.3	1.5	3.2	-0.0	-1.8	-1.2	-1.3	-1.6	-1.0	1.0	-1.3	-1.2	-1.5	-1.1	-0.9	-1.7	-1.5	-1.1	-1.6	-1.2	-0.9	-1.1	-1.4	-0.8	0.4	1.0
Smoking status: Previous	1.3	1.9	8.4	-1.4	-1.5	-1.1	-1.4	-1.5	-0.9	0.9	-1.6	-2.9	-1.6	-1.2	-1.3	-1.4	-1.4	-1.4	-1.7	-0.3	-1.3	-1.3	-1.7	-0.3	-0.3	0.7
Handedness (chirality/laterality): Left-handed	1.3	1.5	2.5	-1.0	1.5	0.9	1.3	1.6	1.2	-1.1	0.9	0.3	1.5	1.1	1.1	1.6	1.4	1.3	1.4	1.3	1.2	1.3	1.3	1.2	-0.9	-1.4
Arm fat mass (left)	1.3	5.3	25.9	-3.8	-3.4	-0.7	-1.9	-3.0	-3.7	0.3	-1.6	-3.3	0.1	-0.6	-0.2	-5.1	-2.6	-0.3	-3.7	-2.4	-0.8	-0.3	-1.6	-0.3	-1.2	-0.5
Basal metabolic rate	1.3	7.4	21.3	-3.1	-3.5	-2.3	-2.7	-3.1	-3.6	1.6	-3.0	-4.6	-1.7	-2.2	-2.1	-3.8	-3.2	-2.0	-3.9	-1.3	-2.3	-2.1	-3.0	-0.5	-1.3	0.9
HDL Cholesterol	1.2	2.0	5.1	1.4	-0.9	-1.5	-1.3	-1.1	0.5	1.6	-1.5	-1.0	-1.7	-1.5	-1.6	-0.5	-1.2	-1.6	-1.0	-1.2	-2.3	-1.4	-1.3	-1.6	1.7	1.7
Serious illness, injury or assault to yourself	1.2	1.5	3.7	1.3	-1.0	-1.1	-1.2	-1.1	-1.3	1.4	-1.1	-0.4	-0.8	-1.1	-1.4	-0.8	-1.2	-1.3	-1.1	-1.3	-1.0	-1.2	-1.1	-1.7	1.9	1.4
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	3.4	-0.1	-1.8	-1.1	-1.2	-1.7	-1.0	1.0	-1.2	-1.3	-1.3	-1.1	-1.1	-1.6	-1.6	-1.2	-1.7	-1.1	-0.9	-1.2	-1.4	-0.8	0.6	0.9
Shortness of breath walking on level ground	1.2	1.5	4.7	-1.6	-1.4	-0.8	-1.2	-1.4	-1.8	0.7	-1.2	-2.2	-0.8	-0.8	-1.0	-1.7	-1.3	-0.9	-1.7	-0.8	-0.8	-0.9	-1.3	-0.5	-0.2	0.6
Medication: Seretide 50 evohaler	1.2	1.4	6.2	-1.4	-1.8	-0.4	-1.1	-1.5	-2.0	0.3	-0.9	-1.6	-0.3	-0.5	-0.2	-2.5	-1.4	-0.3	-1.8	-1.0	-0.6	-0.4	-1.0	-0.0	-0.6	0.0
Whole body fat mass	1.2	5.0	25.3	-4.4	-3.2	-0.5	-1.6	-2.7	-3.4	-0.0	-1.3	-3.0	0.4	-0.3	0.1	-5.0	-2.4	0.1	-3.5	-1.9	-0.6	0.0	-1.3	0.3	-1.9	-1.0
Comparative height size at age 10	1.2	6.6	14.4	-1.7	3.0	2.1	2.6	2.9	2.4	-2.5	2.6	2.6	2.0	2.2	2.1	2.8	2.6	2.1	2.8	3.8	1.4	2.0	2.3	3.1	-3.6	-2.4
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.4	0.5	-1.4	-1.1	-1.1	-1.4	-1.0	1.0	-1.1	-1.3	-0.6	-1.1	-1.2	-1.3	-1.3	-1.3	-1.5	-0.6	-1.4	-1.3	-1.4	-0.6	0.1	0.7
Medication: Aspirin	1.2	1.6	3.9	-1.5	1.1	1.1	1.4	1.2	2.0	-1.3	0.9	-0.1	1.6	1.3	1.2	1.2	1.2	1.4	1.0	1.1	1.0	1.5	1.3	1.2	-0.7	-1.5
Alcohol drinker status: Previous	1.2	1.3	4.3	-0.2	-1.3	-1.0	-1.3	-1.2	-0.9	1.0	-1.3	-2.1	-0.7	-1.0	-1.0	-1.4	-1.3	-1.0	-1.5	-1.2	-0.8	-1.0	-1.4	-1.0	0.9	0.9
Schizophrenia vs Biploar Disorder	1.1	1.4	4.7	0.5	1.2	1.1	1.3	1.1	2.2	-0.9	1.5	1.9	1.4	1.0	0.9	1.2	1.1	0.9	1.4	1.1	0.7	1.0	1.4	0.8	-0.2	-1.0
Eye problems/disorders: None of the above	1.1	1.3	2.3	1.1	-0.9	-1.0	-1.3	-1.2	-1.5	1.1	-0.7	0.5	-1.2	-1.0	-1.1	-1.4	-1.1	-1.1	-1.0	-1.4	-1.0	-1.2	-1.1	-1.3	1.1	1.2
Friendships satisfaction	1.1	1.4	2.9	0.7	-1.0	-1.7	-1.1	-0.9	-1.1	1.5	-1.7	-1.0	-1.4	-1.6	-1.7	-0.3	-1.2	-1.4	-0.9	-0.3	-1.3	-1.4	-1.2	-0.7	0.5	1.1
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	3.4	-1.8	1.5	1.0	1.4	1.5	1.4	-1.1	0.7	0.7	1.2	1.0	1.0	1.9	1.4	1.2	1.5	1.6	1.2	1.2	1.1	1.4	-1.1	-1.2
Tinnitus: Yes, now most or all of the time	1.1	1.3	2.9	-1.2	1.0	1.2	1.2	1.0	0.3	-1.2	1.3	1.1	1.4	1.3	1.2	0.6	1.1	1.5	1.0	0.5	1.7	1.4	1.3	1.1	-0.7	-1.5
Schizophrenia (2018)	1.0	2.1	6.7	2.6	-1.1	-1.8	-0.9	-0.8	1.3	1.8	-1.5	-0.2	-1.8	-1.7	-1.7	0.2	-1.1	-1.5	-0.5	-0.8	-1.8	-1.5	-1.1	-1.4	1.8	1.7
Leg fat-free mass (left)	1.0	5.2	14.6	-3.3	-2.9	-1.7	-2.2	-2.5	-3.7	1.1	-2.4	-3.8	-1.1	-1.6	-1.4	-3.5	-2.6	-1.4	-3.3	-1.0	-1.7	-1.5	-2.3	-0.2	-1.7	0.4
Trunk fat percentage	1.0	4.1	24.2	-4.9	-1.1	1.4	0.3	-0.7	-1.9	-1.9	0.9	-0.6	2.3	1.6	2.1	-3.4	-0.4	2.1	-1.4	-0.4	1.3	2.0	0.9	1.8	-3.1	-2.8
Leg predicted mass (left)	1.0	5.2	14.7	-3.2	-2.9	-1.7	-2.2	-2.5	-3.6	1.1	-2.4	-3.8	-1.1	-1.7	-1.5	-3.4	-2.6	-1.4	-3.3	-1.0	-1.7	-1.5	-2.4	-0.2	-1.6	0.5
Arm fat percentage (right)	1.0	3.9	23.7	-2.7	-2.9	-0.4	-1.6	-2.6	-3.3	0.2	-1.1	-2.0	0.5	-0.2	0.2	-4.9	-2.2	0.2	-3.2	-2.7	-0.4	0.1	-1.0	-0.6	-0.4	-0.5
Gout (self-reported)	1.0	1.4	4.6	-2.1	0.8	1.4	1.1	0.8	0.2	-1.4	1.2	0.2	1.5	1.3	1.4	0.2	1.1	1.4	0.7	0.7	0.8	1.3	1.0	1.2	-1.4	-1.7
Medication: Amlodipine	1.0	1.4	4.2	-2.1	0.6	1.5	1.2	0.8	1.3	-1.4	1.1	-0.5	1.8	1.5	1.3	0.3	1.0	1.4	0.5	0.6	0.9	1.3	1.0	1.1	-0.7	-1.5
Medication: Aspirin	1.0	1.4	3.4	-1.1	1.0	1.2	1.4	1.1	1.8	-1.2	1.0	0.3	1.6	1.4	1.2	1.0	1.2	1.3	0.9	0.8	1.1	1.4	1.3	0.9	-0.3	-1.4
Mineral and other dietary supplements	1.0	1.3	2.2	-0.7	1.1	1.2	1.2	1.4	0.9	-1.2	1.1	0.5	1.5	1.4	1.4	0.8	1.2	1.5	1.0	0.8	1.1	1.5	1.4	1.0	-0.7	-1.2
Pain type(s) experienced in last month: Hip pain	1.0	1.2	3.6	-0.9	-1.2	-1.2	-1.3	-1.2	-1.6	0.9	-1.4	-1.9	-1.2	-1.1	-1.1	-1.1	-1.2	-1.0	-1.2	-0.6	-0.7	-1.0	-1.3	-0.4	-0.2	0.6
Diastolic blood pressure, automated reading	1.0	3.1	14.1	-0.2	-2.8	-1.2	-1.4	-2.6	-2.4	1.0	-1.3	-0.8	-0.4	-1.0	-0.6	-3.8	-2.5	-0.5	-2.8	-2.9	-0.4	-0.5	-1.1	-1.2	1.2	0.2
Supplements: Calcium	1.0	1.2	2.5	0.8	-0.5	-1.0	-1.2	-0.7	-0.9	1.3	-1.0	-0.9	-1.3	-1.2	-1.4	-0.0	-0.7	-1.5	-0.5	-0.5	-1.0	-1.5	-1.4	-1.2	1.1	1.6
Schizophrenia (2014)	0.9	2.1	6.2	2.5	-0.9	-1.6	-1.0	-0.7	1.1	1.7	-1.4	-0.5	-1.7	-1.6	-1.6	0.2	-1.0	-1.6	-0.6	-1.0	-1.8	-1.5	-1.2	-1.6	2.0	1.8
Supplements: Zinc	0.9	0.9	2.2	0.9	-0.6	-1.2	-0.9	-0.6	0.3	1.1	-1.4	-1.5	-1.0	-1.2	-1.2	0.0	-0.7	-1.1	-0.6	-0.5	-1.0	-1.1	-1.1	-0.9	1.0	1.0
Diabetes (mother)	0.9	1.1	2.6	-1.6	0.5	1.2	1.0	0.7	0.4	-1.3	1.0	-0.1	1.6	1.3	1.3	0.1	0.8	1.3	0.5	0.6	1.2	1.3	0.9	1.0	-1.0	-1.5
Trunk fat mass	0.9	3.8	25.3	-5.0	-1.9	0.5	-0.5	-1.5	-2.5	-1.1	-0.2	-2.0	1.4	0.7	1.1	-3.9	-1.3	1.1	-2.3	-0.6	0.3	1.0	-0.2	1.4	-3.0	-2.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	2.4	1.5	-0.8	-1.4	-1.1	-1.0	-1.3	1.2	-1.3	0.1	-1.2	-1.4	-1.2	-0.8	-1.1	-1.0	-0.9	-0.8	-1.1	-1.0	-0.7	-1.0	0.7	1.1
Medication: Ramipril	0.9	1.1	3.7	0.9	-1.0	-1.1	-0.9	-0.9	0.0	1.1	-1.5	-1.9	-1.0	-1.1	-1.1	-0.3	-1.0	-1.0	-0.9	-1.0	-1.2	-1.0	-1.1	-1.0	1.2	1.0
Alcohol intake versus 10 years previously	0.9	1.4	7.7	-1.9	-1.6	-0.0	-0.6	-1.3	-2.4	-0.4	-0.3	-1.2	0.2	0.1	0.4	-2.8	-1.2	0.2	-1.9	-0.8	0.3	0.4	-0.3	0.5	-1.3	-0.7
Headache pain in last month	0.9	1.6	2.8	0.4	-1.5	-1.7	-1.4	-1.4	-0.8	1.3	-1.5	-0.9	-1.6	-1.5	-1.3	-1.4	-1.6	-1.2	-1.5	-1.0	-1.6	-1.2	-1.3	-0.8	0.4	1.0
Chronic bronchitis/emphysema (mother)	0.9	1.0	8.4	-1.0	-1.1	-0.7	-0.9	-1.0	-1.1	0.5	-1.1	-2.9	-0.7	-0.6	-0.4	-1.2	-1.0	-0.6	-1.3	-1.0	-0.3	-0.5	-1.0	-0.5	0.2	0.3
Body fat percentage	0.9	3.5	20.1	-4.0	-2.3	0.5	-0.7	-1.9	-2.6	-0.8	-0.2	-1.5	1.4	0.6	1.1	-4.5	-1.5	1.1	-2.6	-1.7	0.3	1.0	-0.2	0.6	-1.8	-1.7
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	1.7	-0.9	1.2	0.9	0.9	1.1	0.6	-1.0	1.0	0.9	1.0	1.0	1.1	0.9	1.1	1.0	1.1	1.2	1.0	1.1	1.1	1.1	-1.3	-1.1
Arm fat percentage (left)	0.9	3.6	22.0	-3.4	-2.6	0.2	-1.2	-2.2	-3.2	-0.4	-0.5	-1.9	1.0	0.3	0.7	-4.7	-1.8	0.6	-2.9	-2.3	0.1	0.6	-0.6	-0.0	-1.1	-1.1
Commuting to job workplace: Public transport	0.9	1.1	2.8	-0.3	1.6	0.7	0.9	1.3	0.4	-0.7	1.0	1.7	0.9	0.8	0.7	1.2	1.1	1.0	1.4	0.9	1.1	1.0	1.3	0.8	-0.7	-0.8
Heart attack/myocardial infarction (self-reported)	0.9	1.1	3.6	0.6	-1.9	-0.8	-0.9	-1.5	-0.6	0.7	-0.7	-0.6	-0.7	-0.8	-0.7	-1.8	-1.4	-0.9	-1.7	-1.3	-0.7	-1.0	-1.1	-0.8	0.8	0.6
Sensitivity / hurt feelings	0.8	1.3	3.7	-1.4	1.2	0.5	1.2	1.4	1.9	-0.9	0.3	-0.0	0.5	0.7	0.8	1.9	1.1	1.0	1.3	1.8	0.3	1.0	0.9	1.5	-1.3	-1.0
Heart attack	0.8	1.1	3.4	0.6	-1.8	-0.7	-0.9	-1.5	-0.6	0.7	-0.7	-0.6	-0.6	-0.7	-0.7	-1.8	-1.4	-0.9	-1.7	-1.4	-0.6	-0.9	-1.0	-0.8	0.8	0.6
Comparative body size at age 10	0.8	2.3	4.8	0.7	-1.9	-1.1	-1.8	-1.8	-1.4	1.3	-1.5	-2.2	-1.6	-1.2	-1.2	-1.7	-1.4	-1.5	-1.8	-1.3	-1.4	-1.6	-1.8	-1.4	0.8	1.7
Leg fat-free mass (right)	0.8	4.5	12.9	-3.1	-2.6	-1.6	-2.1	-2.3	-3.4	1.1	-2.3	-3.6	-1.1	-1.6	-1.5	-3.0	-2.4	-1.4	-3.0	-0.7	-1.5	-1.5	-2.2	-0.0	-1.7	0.4
Leg predicted mass (right)	0.8	4.3	12.6	-3.2	-2.6	-1.6	-2.0	-2.2	-3.3	1.0	-2.2	-3.6	-1.0	-1.5	-1.4	-3.0	-2.3	-1.3	-2.9	-0.7	-1.5	-1.4	-2.2	0.0	-1.7	0.4
Fractured/broken bones in last 5 years	0.8	1.1	2.1	0.9	-0.6	-1.4	-0.9	-0.4	0.2	1.3	-1.4	-1.1	-1.4	-1.4	-1.3	0.4	-0.7	-1.1	-0.3	-0.5	-1.2	-1.1	-0.9	-1.1	1.3	1.3
Cholesterol lowering medication	0.8	1.1	2.2	-1.3	0.8	1.3	1.1	0.9	1.4	-1.2	0.8	-0.4	1.5	1.3	1.0	0.9	1.1	1.0	0.7	1.2	1.1	1.0	0.8	1.1	-1.0	-1.0
Reaction Time	0.7	1.3	5.0	2.2	-0.1	-0.9	-0.7	-0.1	1.4	1.2	-0.9	-0.8	-1.3	-1.0	-1.1	1.1	-0.2	-1.2	0.2	-0.3	-1.6	-1.2	-0.8	-1.3	1.6	1.7
Coronary Artery Disease (CAD)	0.7	0.8	5.0	-2.2	-0.7	0.4	-0.3	-0.7	-1.7	-0.5	0.0	-1.5	0.8	0.3	0.3	-1.5	-0.4	0.3	-0.9	-0.3	0.4	0.3	-0.3	0.5	-1.0	-0.6
Respiratory disease	0.7	1.6	13.2	-1.6	-0.9	-1.2	-1.1	-0.8	-0.8	0.7	-1.9	-3.6	-1.0	-1.1	-1.0	-0.5	-0.9	-0.7	-1.0	0.4	-1.2	-0.8	-1.3	0.3	-1.1	0.5
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	1.8	-0.5	0.7	1.1	1.1	0.8	0.5	-1.0	1.0	0.3	1.3	1.0	0.8	0.7	1.0	0.9	0.8	0.7	0.8	0.9	0.8	0.8	-0.7	-1.0
Medication for hormone replacement therapy	0.7	0.8	3.2	-0.7	-0.7	-0.7	-1.0	-1.0	-1.8	0.7	-0.7	-0.6	-1.0	-0.9	-0.8	-1.1	-0.9	-0.8	-1.0	-0.6	-0.9	-0.8	-1.0	-0.5	-0.2	0.5
Hand grip strength (right)	0.7	1.9	13.6	-1.6	-1.5	-0.3	-1.1	-1.7	-3.7	0.1	-0.3	-0.6	-0.6	-0.5	-0.6	-2.7	-1.4	-0.8	-2.0	-0.1	-0.2	-0.8	-1.2	0.5	-2.0	0.0
Hearing difficulty/problems with background noise	0.7	1.2	5.3	-1.2	-0.7	-1.3	-0.9	-0.6	0.1	1.0	-1.5	-2.3	-0.8	-1.3	-1.4	0.1	-0.8	-1.2	-0.7	0.7	-1.4	-1.1	-1.1	0.2	-0.9	0.6
Birth weight	0.7	1.6	2.9	0.9	-1.4	-1.7	-1.3	-1.2	-1.4	1.4	-1.3	0.4	-1.6	-1.6	-1.4	-1.1	-1.5	-1.4	-1.1	-0.6	-1.3	-1.4	-1.1	-0.7	0.4	1.2
Mean time to correctly identify matches	0.7	1.3	5.3	2.3	-0.1	-0.7	-0.7	-0.2	1.4	1.1	-0.7	-0.7	-1.3	-0.9	-1.1	1.0	-0.1	-1.3	0.1	-0.5	-1.1	-1.2	-0.8	-1.5	1.9	1.8
Suffer from ‘nerves’	0.7	1.1	3.5	0.8	-1.2	-1.2	-0.9	-1.1	-0.8	1.1	-1.1	-0.0	-0.9	-1.0	-1.0	-1.2	-1.2	-1.0	-1.1	-1.1	-1.9	-1.0	-1.0	-0.9	0.6	0.9
Hearing aid user	0.7	0.8	1.5	-0.9	0.9	0.8	1.0	1.0	0.8	-0.9	0.7	0.3	0.8	0.8	0.9	1.0	0.9	0.9	0.9	1.2	0.7	0.8	0.9	1.2	-1.2	-1.0
Risk taking	0.7	1.0	1.9	0.3	-1.3	-1.0	-1.0	-1.3	-0.8	0.9	-0.9	-0.7	-1.0	-1.1	-1.2	-1.0	-1.1	-1.4	-1.2	-0.5	-0.8	-1.3	-1.3	-0.6	0.1	0.8
Fasting Glucose	0.6	0.7	4.9	-0.5	-0.8	0.1	-0.5	-1.1	-2.2	-0.1	0.2	0.4	0.4	0.2	0.2	-2.2	-0.8	0.3	-1.2	-1.2	0.3	0.3	-0.2	-0.2	0.1	-0.4
Hand grip strength (left)	0.6	1.6	12.2	-1.3	-1.3	-0.4	-1.0	-1.6	-3.5	0.2	-0.3	0.2	-0.4	-0.5	-0.6	-2.6	-1.4	-0.7	-1.9	-0.5	-0.5	-0.6	-0.9	0.2	-1.4	0.1
Ever had hysterectomy (womb removed)	0.6	0.7	2.6	-0.3	-0.7	-0.6	-1.0	-0.9	-1.6	0.6	-0.8	-0.8	-0.9	-0.6	-0.4	-1.3	-0.9	-0.6	-1.0	-1.1	-0.1	-0.6	-0.8	-0.7	0.3	0.6
Average weekly fortified wine intake	0.6	0.7	1.8	-1.2	-0.8	-0.9	-1.1	-0.9	-1.1	0.7	-1.1	-1.3	-0.6	-0.9	-0.8	-1.0	-1.0	-0.7	-0.9	-0.5	-0.6	-0.7	-0.9	-0.4	-0.3	0.5
Medication: Atenolol	0.6	0.7	2.5	-0.6	-1.1	-0.4	-0.8	-1.2	-1.1	0.5	-0.7	-1.2	-0.4	-0.5	-0.4	-1.6	-1.0	-0.5	-1.4	-1.4	-0.5	-0.3	-0.6	-0.9	0.5	0.4
Waist circumference	0.6	2.3	18.4	-4.3	-1.1	0.5	0.1	-0.7	-0.9	-1.1	-0.2	-2.0	1.4	0.7	1.0	-2.1	-0.5	1.2	-1.3	0.1	0.5	1.1	0.1	1.6	-2.4	-1.9
Worrier / anxious feelings	0.6	1.1	2.7	1.1	-1.2	-1.4	-1.0	-1.1	-1.2	1.2	-1.2	0.2	-0.7	-1.2	-0.9	-1.0	-1.2	-0.7	-0.9	-1.6	-1.0	-0.7	-0.8	-1.1	1.1	0.6
Medication: Ventolin 100micrograms inhaler	0.6	0.7	4.0	-2.0	0.1	0.8	0.4	0.1	-0.5	-1.0	0.3	-1.2	0.7	0.7	0.9	-0.4	0.3	0.9	-0.0	0.6	0.8	0.8	0.3	1.1	-1.6	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.8	2.9	-0.2	-1.3	-0.7	-0.9	-1.2	-0.7	0.4	-0.7	-1.7	-1.0	-0.7	-0.5	-1.3	-0.9	-0.7	-1.3	-0.4	-0.2	-0.8	-1.0	-0.1	-0.4	0.4
Alzheimer’s Disease (in father)	0.5	0.5	1.1	-0.7	0.4	1.1	0.8	0.5	0.3	-1.0	0.9	0.4	0.9	1.0	1.0	0.2	0.6	0.8	0.4	0.4	0.8	0.8	0.7	0.7	-0.7	-0.8
Mean Putamen Volume	0.5	0.6	1.3	-0.7	0.7	0.7	0.7	0.9	1.2	-0.7	0.7	0.3	0.2	0.6	0.8	1.0	0.8	0.6	0.9	1.1	0.6	0.6	0.7	1.0	-0.9	-0.6
Lupus	0.5	0.7	2.9	-0.1	-0.7	-0.9	-0.8	-0.6	-0.4	0.9	-1.0	-1.7	-1.3	-0.9	-0.9	0.1	-0.7	-1.2	-0.6	0.1	-0.3	-1.2	-1.1	-0.5	0.2	1.1
Blood Platelet Count	0.5	5.3	13.5	-2.9	3.0	1.5	2.3	3.0	2.3	-1.8	0.9	-1.4	1.8	1.6	1.6	3.7	2.5	2.0	2.7	3.5	0.5	1.9	1.8	2.6	-2.6	-1.8
Severe depression (siblings)	0.5	0.6	1.5	1.2	0.2	-0.7	-0.5	0.1	0.6	0.8	-0.8	-1.2	-0.9	-0.7	-0.7	0.9	-0.0	-0.7	0.3	-0.4	-0.6	-0.6	-0.4	-1.0	1.2	1.1
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.6	-1.1	-0.8	-0.6	-0.8	-0.9	-1.2	0.3	-0.9	-1.3	-0.4	-0.5	-0.3	-1.2	-0.9	-0.3	-1.0	-0.4	-0.2	-0.3	-0.7	-0.0	-0.5	0.1
Supplements: Glucosamine	0.5	0.7	1.2	0.6	-1.1	-0.8	-0.8	-1.1	-0.9	0.8	-0.5	0.6	-1.0	-1.0	-0.9	-1.0	-1.0	-1.0	-0.9	-0.6	-0.5	-1.0	-0.8	-0.5	0.3	0.8
Prospective memory result	0.5	0.6	3.1	-0.9	-1.1	-0.1	-0.7	-1.0	-1.8	0.1	-0.3	-1.1	0.2	-0.2	-0.1	-1.6	-0.7	-0.2	-1.0	-0.7	-0.4	-0.3	-0.7	-0.0	-0.5	-0.0
Peak expiratory flow (PEF)	0.5	1.2	6.5	1.8	0.8	0.2	1.1	1.1	1.9	-0.3	0.7	2.5	0.2	0.2	0.1	2.1	0.9	0.2	1.4	1.2	0.7	0.2	1.0	0.5	0.2	-0.1
Alcohol intake frequency.	0.5	1.1	3.8	-2.0	-0.4	1.1	0.8	-0.1	-0.7	-1.3	0.8	-0.0	1.4	1.1	1.3	-1.3	-0.0	1.4	-0.6	-0.1	1.4	1.3	0.8	1.0	-0.9	-1.3
Breast cancer (self-reported)	0.5	0.6	4.1	-2.0	-0.5	0.4	-0.4	-0.7	-1.6	-0.3	0.1	-1.2	-0.1	0.1	-0.2	-1.0	-0.3	-0.4	-0.9	0.5	0.3	-0.5	-0.8	0.6	-1.3	-0.0
Wears glasses or contact lenses	0.5	0.6	4.3	-2.1	0.5	0.7	0.4	0.4	0.2	-0.8	0.3	-0.6	0.5	0.7	0.8	0.1	0.6	0.8	0.4	0.6	0.5	0.7	0.3	0.9	-1.3	-1.1
Medication: Blood pressure	0.5	1.0	3.5	-1.2	0.7	1.0	1.2	0.8	1.9	-0.9	0.5	-0.7	1.4	1.0	0.9	1.0	1.0	1.3	0.7	0.6	1.0	1.2	1.0	0.7	0.0	-0.9
Basal cell carcinoma (self-reported)	0.5	0.6	2.8	0.7	1.1	0.1	0.6	1.0	1.2	-0.1	0.4	1.1	0.4	0.2	0.1	1.7	0.8	0.2	1.3	1.1	0.5	0.3	0.7	0.4	-0.1	-0.0
Worry (Nagel 2018)	0.4	0.9	2.2	1.2	-1.0	-1.2	-0.7	-1.0	-0.6	1.1	-1.2	0.0	-0.9	-1.2	-1.0	-0.8	-1.0	-0.8	-0.8	-1.2	-1.5	-0.8	-0.8	-0.8	0.9	0.7
LDL Cholesterol	0.4	0.7	1.6	-1.1	0.5	0.7	0.8	0.6	-0.0	-0.8	0.8	0.9	1.3	0.8	0.9	0.2	0.6	1.0	0.6	0.5	0.8	1.0	0.9	0.9	-0.8	-1.2
Hearing difficulty/problems: Yes	0.4	0.7	4.2	-2.0	0.3	0.6	0.6	0.5	0.6	-0.7	0.4	-0.6	0.9	0.6	0.5	0.3	0.5	0.6	0.4	1.0	0.4	0.7	0.4	1.2	-1.4	-1.0
High blood pressure	0.4	1.1	2.5	0.1	-1.2	-1.2	-0.8	-1.0	0.3	1.1	-1.5	-1.5	-0.7	-1.1	-1.2	-0.5	-1.1	-0.7	-1.0	-1.2	-0.9	-0.9	-1.0	-1.0	1.6	0.7
Hair/balding pattern: Pattern 2	0.4	0.5	3.6	0.5	-0.3	-0.7	-0.4	-0.4	0.4	0.5	-0.9	-1.9	-0.7	-0.7	-0.7	0.3	-0.3	-0.7	-0.4	0.2	-1.1	-0.7	-0.7	-0.2	-0.1	0.7
Number of live births	0.4	0.5	4.5	-2.1	-0.3	0.3	0.2	-0.0	-0.2	-0.6	-0.0	-0.4	0.6	0.5	0.8	-0.9	-0.1	0.9	-0.3	0.0	0.3	0.9	0.4	0.8	-1.1	-0.9
Asthma	0.4	0.7	6.5	-2.3	0.2	0.2	-0.2	0.2	-0.5	-0.4	-0.5	-2.5	0.2	0.3	0.4	-0.1	0.2	0.4	-0.1	0.8	0.3	0.3	-0.2	0.9	-1.5	-0.4
Medication: Lansoprazole	0.4	0.5	1.7	-0.7	-1.1	-0.5	-0.6	-1.0	-1.1	0.3	-0.4	-1.0	-0.4	-0.4	-0.3	-1.3	-0.9	-0.4	-1.1	-0.6	0.1	-0.4	-0.6	-0.1	-0.1	0.1
Pulse wave Arterial Stiffness index	0.4	0.4	3.8	-1.9	0.1	0.4	0.3	0.1	-0.0	-0.6	0.3	-0.9	0.3	0.5	0.5	-0.1	0.2	0.5	0.1	0.7	0.4	0.4	0.1	0.9	-1.3	-0.8
Hair/balding pattern: Pattern 4	0.4	1.0	4.3	-0.3	-1.7	-0.8	-0.8	-1.4	-1.4	0.6	-0.7	0.2	-0.3	-0.8	-0.6	-2.1	-1.5	-0.6	-1.6	-1.1	-0.5	-0.6	-0.6	-0.3	0.0	0.1
Loud music exposure frequency	0.4	0.4	4.1	0.9	0.4	-0.1	0.5	0.6	2.0	-0.0	-0.0	-0.0	-0.2	-0.1	-0.1	1.4	0.4	-0.0	0.6	0.8	-0.1	-0.0	0.3	0.3	-0.0	0.1
Average weekly red wine intake	0.4	0.6	5.1	0.6	0.7	0.3	0.7	0.6	0.2	-0.4	0.8	2.2	0.4	0.4	0.5	0.6	0.5	0.5	0.8	0.7	0.8	0.6	0.9	0.6	-0.4	-0.6
Long-standing illness, disability or infirmity	0.4	0.6	6.7	-1.7	-0.2	0.3	0.3	0.1	1.0	-0.4	-0.4	-2.6	0.3	0.2	0.1	0.5	0.2	0.3	-0.1	0.9	-0.1	0.2	-0.2	0.8	-0.8	-0.4
Medication for cholesterol	0.4	0.6	2.7	1.6	-0.4	-1.0	-0.6	-0.3	-0.2	0.9	-0.6	0.7	-1.0	-0.9	-0.8	0.0	-0.6	-0.9	-0.1	-0.4	-0.9	-0.8	-0.6	-0.7	0.8	1.0
Asthma (self-reported)	0.4	0.8	6.4	-2.3	0.2	0.2	-0.2	0.2	-0.6	-0.5	-0.5	-2.5	0.2	0.3	0.4	-0.1	0.2	0.5	-0.1	0.8	0.3	0.3	-0.2	0.9	-1.6	-0.4
Average weekly champagne plus white wine intake	0.4	0.6	2.8	0.4	1.1	0.4	0.6	1.0	1.3	-0.3	0.4	0.0	0.3	0.3	0.1	1.7	0.9	0.1	1.2	1.4	0.0	0.1	0.4	0.5	-0.5	-0.0
Myopia	0.4	0.6	2.6	0.1	1.6	0.5	0.4	1.3	0.2	-0.3	0.5	1.2	0.2	0.6	0.4	1.4	1.2	0.7	1.4	0.4	0.8	0.6	0.8	-0.1	0.4	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.2	2.4	-0.1	1.5	1.2	0.8	1.2	-0.3	-1.1	1.5	1.6	0.5	1.1	1.1	0.9	1.2	0.6	1.2	1.4	1.0	0.7	0.9	1.0	-1.6	-0.6
Alzheimer’s Disease (in mother)	0.3	0.3	1.3	-0.9	0.3	0.7	0.4	0.1	0.1	-0.7	0.4	-0.7	0.2	0.6	0.3	0.1	0.4	0.3	0.1	1.0	0.7	0.2	0.2	0.9	-1.2	-0.5
Primary Biliary Cirrhosis	0.3	0.5	4.5	2.1	0.0	-0.6	-0.3	0.0	0.6	0.7	-0.4	0.4	-1.0	-0.7	-0.5	0.6	-0.1	-0.6	0.2	-0.1	-0.2	-0.6	-0.2	-0.7	0.8	0.9
Rheumatoid Arthritis	0.3	0.4	1.1	0.3	-0.4	-0.8	-0.5	-0.3	0.1	0.8	-0.8	-0.6	-0.6	-0.8	-0.7	-0.0	-0.6	-0.6	-0.4	-0.6	-0.9	-0.5	-0.5	-0.7	1.0	0.7
Systolic Blood Pressure	0.3	1.6	5.1	0.3	-2.2	-0.9	-0.8	-1.9	-0.5	0.8	-1.3	-1.0	-0.5	-0.9	-0.5	-2.3	-1.7	-0.3	-2.0	-2.2	-0.2	-0.4	-0.9	-0.9	1.6	0.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.7	-0.3	0.6	-0.3	0.0	0.6	1.0	0.3	-0.6	-1.6	-0.5	-0.3	-0.5	1.5	0.4	-0.3	0.5	0.7	-0.5	-0.3	-0.3	-0.1	0.6	0.5
Ever used hormone-replacement therapy (HRT)	0.3	0.4	3.5	-1.9	0.2	0.1	-0.2	-0.0	-0.2	-0.1	-0.2	-1.7	-0.2	0.0	-0.2	0.2	0.2	-0.1	0.0	0.6	0.0	-0.2	-0.4	0.4	-0.9	-0.0
Angina	0.3	0.4	3.2	-1.8	0.1	0.5	0.4	0.4	0.7	-0.6	0.2	-0.2	1.1	0.6	0.6	-0.0	0.3	0.7	0.1	0.3	0.1	0.8	0.6	0.6	-0.7	-0.9
Nervous feelings	0.3	0.6	1.6	0.1	1.0	0.3	0.9	1.1	1.2	-0.6	0.2	0.3	0.3	0.5	0.7	1.2	0.8	0.8	1.1	1.0	0.1	0.9	0.9	1.0	-0.9	-0.8
Mouth/teeth dental problems	0.3	0.4	1.5	1.2	0.8	0.7	0.4	0.5	0.1	-0.4	1.0	1.0	0.6	0.5	0.4	0.5	0.6	0.3	0.7	0.1	1.1	0.4	0.6	-0.2	0.5	0.0
Allergy	0.3	0.7	4.5	1.6	-0.1	0.9	0.9	0.1	1.4	-0.5	1.3	2.1	0.7	0.7	0.5	0.1	0.3	0.2	0.2	-0.3	0.4	0.2	0.6	-0.2	0.9	-0.2
Length of working week for main job	0.3	0.3	1.9	1.4	-0.7	0.3	0.3	-0.4	1.0	-0.2	0.5	0.6	0.2	0.3	0.3	-0.7	-0.3	0.1	-0.5	-0.5	-0.8	0.1	0.1	-0.2	0.8	0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.9	0.8	0.4	-0.8	0.2	0.4	1.4	0.4	-0.7	-0.2	-0.9	-0.6	-0.5	1.3	0.1	-0.5	0.5	0.8	-0.9	-0.4	-0.2	0.2	-0.1	0.3
Medication: Blood pressure	0.3	0.5	3.4	-1.8	-0.3	0.7	0.3	-0.2	-0.3	-0.7	0.2	-1.0	0.8	0.8	0.7	-0.7	0.1	0.7	-0.4	-0.4	0.7	0.6	0.1	0.3	-0.2	-0.8
Angina (self-reported)	0.3	0.4	2.5	-1.6	0.1	0.5	0.4	0.4	0.9	-0.5	0.2	-0.3	1.1	0.6	0.5	0.1	0.3	0.6	0.1	0.3	0.1	0.7	0.5	0.5	-0.6	-0.7
Commuting to job workplace: Walk	0.3	0.3	1.0	0.4	0.7	0.4	0.7	0.6	0.7	-0.3	0.7	1.0	0.8	0.4	0.2	0.8	0.5	0.4	0.7	0.6	-0.3	0.4	0.7	0.4	-0.1	-0.4
Eye problems/disorders: Glaucoma	0.3	0.3	1.5	-0.2	0.4	0.6	0.8	0.5	0.9	-0.5	0.6	0.1	1.2	0.7	0.4	0.8	0.6	0.4	0.5	0.4	0.4	0.4	0.5	0.3	0.1	-0.5
Medication: Lisinopril	0.3	0.4	0.9	-0.8	0.7	0.8	0.7	0.7	0.6	-0.7	0.5	-0.6	0.8	0.8	0.6	0.6	0.7	0.8	0.6	0.4	0.9	0.8	0.6	0.3	0.0	-0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	1.7	-0.9	0.2	0.8	0.4	-0.1	-0.5	-0.7	0.6	-0.3	0.4	0.6	0.3	-0.2	0.3	0.2	-0.1	0.8	0.6	0.2	0.1	0.9	-1.3	-0.5
Body Mass Index (BMI) (2010)	0.2	0.3	1.7	-1.1	-0.6	0.2	-0.3	-0.5	-0.8	-0.0	-0.1	-1.3	0.2	0.1	0.0	-0.9	-0.3	0.0	-0.6	-0.8	-0.2	-0.0	-0.4	-0.3	0.3	-0.1
Type 2 Diabetes (T2D) (2012)	0.2	0.2	1.9	-0.1	-0.2	-0.0	0.1	-0.3	0.1	-0.2	-0.0	-0.1	0.2	-0.0	-0.1	-0.3	-0.2	-0.0	-0.2	1.0	0.3	-0.1	0.0	0.8	-1.4	-0.4
Hair Pigment	0.2	5.0	7.8	2.8	-1.8	-2.5	-2.2	-1.9	-1.2	2.5	-2.4	-1.2	-2.6	-2.5	-2.2	-1.2	-2.1	-2.5	-1.8	-2.0	-2.5	-2.4	-2.1	-2.6	2.4	2.8
Hair/balding pattern: Pattern 3	0.2	0.3	2.5	0.3	-0.3	0.1	-0.3	-0.5	-0.7	0.1	0.5	1.6	-0.1	0.1	0.1	-1.0	-0.3	-0.0	-0.2	-0.8	0.3	-0.1	-0.1	-0.4	0.3	0.1
High blood pressure (siblings)	0.2	0.3	1.5	0.0	-0.5	-0.2	-0.4	-0.5	-0.3	0.3	-0.5	-0.9	-0.3	-0.2	-0.2	-0.6	-0.4	-0.1	-0.7	-0.9	-0.5	-0.2	-0.5	-0.7	1.2	0.5
Pulse wave peak to peak time	0.2	0.2	2.4	1.5	0.1	-0.3	-0.0	0.2	0.2	0.4	-0.1	1.1	-0.1	-0.3	-0.4	0.3	-0.1	-0.3	0.1	-0.3	-0.3	-0.2	0.1	-0.5	0.8	0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.5	-0.2	-0.3	0.0	0.4	-0.1	0.7	-0.3	0.2	1.2	0.3	0.2	0.4	-0.5	-0.2	0.4	-0.1	0.0	-0.6	0.4	0.3	0.5	-0.7	-0.7
Migraine (self-reported)	0.2	0.2	0.7	-0.0	-0.4	-0.6	0.0	-0.2	0.2	0.3	-0.5	-0.1	-0.8	-0.5	-0.5	0.4	-0.3	-0.5	-0.1	0.7	-0.8	-0.6	-0.4	0.4	-0.8	0.2
Heart disease (mother)	0.2	0.3	0.6	-0.1	-0.6	-0.5	-0.6	-0.6	-0.7	0.6	-0.4	-0.2	-0.4	-0.4	-0.5	-0.5	-0.5	-0.6	-0.5	-0.8	-0.4	-0.6	-0.7	-0.7	0.7	0.5
Hypertension (Self-reported)	0.2	0.7	2.5	0.0	-0.9	-0.9	-0.5	-0.7	0.8	0.9	-1.2	-1.5	-0.4	-0.8	-0.9	-0.1	-0.7	-0.4	-0.7	-0.9	-0.6	-0.6	-0.6	-0.8	1.6	0.5
Illnesses of father: Heart disease	0.2	0.3	1.3	0.8	-0.2	-0.5	-0.4	-0.3	-0.1	0.6	-0.7	-0.9	-0.2	-0.5	-0.5	0.1	-0.3	-0.4	-0.2	-0.8	-0.5	-0.4	-0.5	-0.9	1.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.3	-1.2	0.7	0.1	0.5	0.7	0.4	-0.5	0.2	-0.2	-0.2	0.2	0.1	0.9	0.4	0.2	0.5	1.5	-0.4	0.1	0.1	1.2	-1.5	-0.4
Medication: Gliclazide	0.2	0.2	0.5	-0.3	0.4	0.7	0.6	0.5	0.2	-0.7	0.4	-0.5	0.7	0.6	0.5	0.5	0.6	0.5	0.4	0.5	0.1	0.4	0.3	0.4	-0.6	-0.6
Allergy or Eczema	0.1	0.2	1.3	-1.2	0.7	-0.2	-0.3	0.4	-1.0	0.1	-0.3	-0.4	0.1	-0.1	-0.0	0.3	0.3	0.3	0.4	-0.1	0.5	0.2	0.1	-0.1	-0.0	-0.1
Cardiovascular Disease	0.1	0.4	1.4	-0.5	-1.2	-0.3	-0.0	-0.8	0.4	0.2	-0.5	-0.6	0.2	-0.2	-0.1	-0.9	-0.7	0.1	-0.9	-1.1	-0.1	0.1	-0.2	-0.4	1.1	-0.3
Hayfever, allergic rhinitis or eczema	0.1	0.2	1.9	-0.7	0.7	-0.4	-0.5	0.3	-1.4	0.4	-0.5	-0.5	-0.1	-0.3	-0.2	0.2	0.1	0.1	0.3	-0.2	-0.2	0.1	-0.0	-0.3	0.0	0.1
Falls in the last year	0.1	0.2	2.5	-0.1	0.0	-0.2	-0.1	0.1	0.7	0.2	-0.4	-1.6	-0.2	-0.1	-0.2	0.5	0.1	-0.3	0.1	0.2	-0.5	-0.3	-0.4	-0.2	0.2	0.3
Breastfed as a baby	0.1	0.2	0.7	0.6	0.6	0.0	-0.1	0.3	-0.3	-0.0	0.1	0.8	-0.4	-0.1	-0.2	0.4	0.3	-0.2	0.3	0.7	-0.1	-0.3	-0.0	0.2	-0.7	0.4
Birth weight of first child	0.1	0.2	1.4	0.2	0.4	-0.3	0.1	0.5	0.3	0.1	-0.2	0.3	-0.2	-0.3	-0.2	0.9	0.1	-0.4	0.4	1.2	-0.5	-0.3	-0.1	0.5	-1.0	0.2
Supplements: Vitamin C	0.1	0.1	0.4	-0.6	0.0	-0.3	-0.4	-0.2	-0.5	0.3	-0.4	-0.6	-0.3	-0.4	-0.3	-0.4	-0.3	-0.2	-0.2	-0.1	-0.5	-0.1	-0.2	0.1	-0.3	0.1
Eye problems/disorders: Cataract	0.1	0.1	1.4	0.4	-0.1	-0.1	0.3	0.2	1.2	-0.1	-0.1	-0.3	-0.4	-0.0	0.1	0.5	0.1	0.1	0.2	0.6	0.2	0.1	0.2	0.5	-0.2	-0.1
Illnesses of father: None of the above (group 1)	0.1	0.1	0.9	0.2	-0.0	0.3	0.2	-0.0	-0.5	-0.3	0.5	0.9	-0.2	0.2	0.2	-0.2	0.0	-0.1	0.1	0.4	-0.1	-0.0	0.1	0.5	-0.8	-0.2
Medication: Bendroflumethiazide	0.1	0.2	1.1	-1.0	-0.0	0.5	0.4	-0.0	0.5	-0.4	0.2	-0.3	0.8	0.4	0.3	-0.0	0.1	0.4	-0.0	0.2	0.1	0.4	0.2	0.4	-0.3	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.4	-0.2	-0.3	-0.6	-0.3	-0.4	-0.0	0.4	-0.6	-0.3	-0.6	-0.5	-0.4	-0.2	-0.5	-0.3	-0.3	-0.3	-0.4	-0.2	-0.2	-0.3	0.3	0.4
Tanning	0.0	0.3	1.6	0.2	-0.5	0.1	-0.4	-0.3	-0.8	0.1	0.0	-0.4	0.5	0.2	0.4	-1.1	-0.3	0.3	-0.4	-1.3	0.5	0.4	0.1	-0.5	0.6	-0.1
Blood clot in the leg (DVT)	0.0	0.0	0.2	-0.4	-0.0	-0.3	-0.1	-0.1	0.2	0.1	-0.3	-0.1	-0.4	-0.2	-0.1	0.1	-0.2	-0.1	-0.1	0.1	-0.1	0.1	0.0	0.0	-0.1	0.1
Supplements: Fish oil (including cod liver oil)	0.0	0.1	0.6	0.0	-0.2	0.1	0.1	-0.4	0.1	0.0	0.3	0.8	0.1	-0.1	-0.2	-0.2	-0.1	-0.1	-0.0	-0.2	0.2	-0.2	-0.1	-0.0	0.3	-0.2

Hub : Genes

NICN1

Models

Trait associations