Best TWAS P=6.22e-08 · Best GWAS P=1.95e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Whole Blood | SNX1 | 0.09 | 0.02 | lasso | 2 | 0.02 | 1.3e-02 | -4.8 | -5.4 | 6.2e-08 | 0.96 | 0.02 | 0.73 | TRUE |
2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | SNX1 | 0.11 | 0.12 | blup | 34 | 0.13 | 7.2e-04 | -5.0 | -5.3 | 1.1e-07 | 0.92 | 0.01 | 0.73 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | SNX22 | 0.05 | 0.07 | blup | 26 | 0.06 | 1.3e-06 | -4.7 | -5.2 | 1.8e-07 | 0.86 | 0.02 | 0.97 | FALSE |