Best TWAS P=1.49e-10 · Best GWAS P=2.11e-08 conditioned to 0.893
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | LRP1 | 0.15 | 0.12 | lasso | 2 | 0.10 | 3.9e-08 | 5.3 | -5.4 | 7.7e-08 | -0.87 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | STAT6 | 0.04 | 0.01 | blup | 47 | 0.01 | 2.3e-02 | 5.4 | 6.4 | 1.5e-10 | 0.86 | 0.00 | 0.94 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | TMEM194A | 0.15 | 0.07 | blup | 43 | 0.09 | 1.9e-09 | 3.8 | 5.8 | 4.9e-09 | 0.51 | 0.23 | 0.66 | FALSE |