TWAS hub - SNX1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0740	0.0250	1.9e-06	0.062	0.051	0.039	0.050	0.055	5.5e-08	7.3e-07	1.4e-05	9.5e-07	2.8e-07
2	GTEx	Artery Tibial	0.0921	0.0399	2.6e-03	0.033	NA	-0.001	NA	0.013	1.3e-03	NA	3.9e-01	NA	3.1e-02
3	GTEx	Breast Mammary Tissue	0.1530	0.0560	3.4e-04	0.092	NA	0.048	NA	0.078	1.9e-05	NA	1.7e-03	NA	8.0e-05
4	GTEx	Breast Mammary Tissue (Male)	0.1775	0.1053	6.2e-02	0.194	NA	0.130	NA	0.187	2.9e-05	NA	6.5e-04	NA	4.0e-05
5	GTEx	Breast Mammary Tissue (Female)	0.0379	0.0445	2.1e-01	-0.009	NA	-0.007	NA	0.036	7.9e-01	NA	5.8e-01	NA	3.0e-02
6	GTEx	Cells EBV-transformed lymphocytes	0.2570	0.0850	2.3e-04	0.237	NA	0.230	NA	0.225	2.7e-08	NA	4.6e-08	NA	6.5e-08
7	GTEx	Cells Transformed fibroblasts	0.2650	0.0650	3.7e-08	0.108	NA	0.109	NA	0.088	1.9e-08	NA	1.6e-08	NA	3.6e-07
8	GTEx	Whole Blood	0.0890	0.0430	7.6e-03	0.021	NA	0.001	NA	0.015	4.7e-03	NA	2.7e-01	NA	1.3e-02
9	METSIM	Adipose	0.0386	0.0172	1.0e-04	0.032	0.027	0.032	0.030	0.031	1.2e-05	5.0e-05	1.3e-05	2.1e-05	1.8e-05
10	NTR	Blood	0.0258	0.0107	5.1e-05	0.022	0.015	0.013	0.016	0.019	8.5e-08	8.7e-06	2.6e-05	6.1e-06	6.7e-07
11	TCGA	Glioblastoma Multiforme	0.1680	0.1100	6.6e-03	0.037	0.042	0.015	NA	0.034	2.8e-02	2.0e-02	1.1e-01	NA	3.2e-02
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.1117	0.0490	4.8e-06	0.049	0.052	0.038	NA	0.047	3.1e-06	1.7e-06	3.4e-05	NA	4.8e-06
13	TCGA	Prostate Adenocarcinoma	0.1325	0.0708	6.0e-04	0.010	0.018	0.003	NA	0.015	3.0e-02	5.3e-03	1.6e-01	NA	9.7e-03
14	TCGA	Rectum Adenocarcinoma	0.1120	0.0640	2.5e-03	0.123	0.126	0.104	NA	0.120	8.5e-04	7.2e-04	2.1e-03	NA	9.7e-04
15	TCGA	Stomach Adenocarcinoma	0.0380	0.0250	4.0e-03	0.047	0.032	0.037	NA	0.036	2.5e-04	2.0e-03	1.1e-03	NA	1.2e-03
16	TCGA	Thyroid Carcinoma	0.0860	0.0420	3.6e-12	0.134	0.115	0.097	NA	0.123	5.5e-13	3.0e-11	1.2e-09	NA	5.8e-12

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Vitamin and mineral supplements	11.1	15.0	29.3	4.8	-1.9	-1.8	-1.8	-3.0	-2.3	-2.7	-5.4	-3.1	-4.5	-4.7	-4.0	-2.9	-5.3	-5.1	-5.0
Multivitamins +/- minerals	11.1	14.1	21.5	-3.3	2.8	2.9	2.9	3.5	3.1	4.0	4.6	3.2	4.3	4.6	4.3	2.7	4.4	4.5	4.0
Deep venous thrombosis (DVT) (self-reported)	6.4	8.2	15.7	3.1	-0.7	-0.9	-0.9	-2.9	-1.4	-3.1	-3.7	-2.6	-3.5	-3.9	-2.7	-1.2	-4.0	-3.7	-3.6
Blood clot in the leg (DVT)	6.0	7.7	14.4	3.0	-0.8	-1.0	-1.0	-2.8	-1.4	-3.0	-3.7	-2.5	-3.4	-3.7	-2.7	-1.3	-3.8	-3.6	-3.4
Illnesses of father: None of the above (group 1)	6.0	7.4	13.2	2.6	-1.9	-1.6	-1.9	-3.1	-2.4	-0.8	-3.0	-3.1	-3.6	-3.4	-3.2	-1.3	-3.2	-3.6	-2.6
Reason for reducing amount of alcohol drunk: Health precaution	5.5	6.4	10.4	-2.5	1.5	1.4	1.4	1.7	1.8	2.5	3.0	3.0	3.2	2.8	2.5	3.0	2.9	3.2	2.7
Lung cancer (father)	5.2	6.1	10.8	2.5	-1.7	-1.6	-1.6	-2.3	-2.0	-1.8	-3.1	-2.1	-3.1	-2.9	-2.9	-2.2	-2.9	-3.3	-2.5
Supplements: Calcium	5.0	5.6	14.2	-3.6	-0.6	-0.5	-0.5	0.4	-0.3	1.6	3.7	0.4	3.0	2.5	1.9	1.1	3.6	3.1	3.8
Blood White Count	4.8	35.4	100.0	3.6	-3.3	-3.8	-4.3	-10.0	-5.4	-5.0	-5.8	-7.5	-6.4	-9.0	-5.2	-1.1	-7.0	-6.3	-5.2
Illnesses of father: High blood pressure	4.4	5.4	11.6	-1.6	2.5	2.2	2.0	2.5	2.7	0.6	2.4	3.4	2.9	2.6	2.2	1.3	2.1	2.7	1.8
Commuting to job workplace: Car/motor vehicle	4.3	5.0	11.0	0.9	-3.2	-3.1	-3.3	-1.0	-2.9	-2.2	-2.1	-2.4	-1.6	-1.1	-2.5	-2.6	-1.1	-2.1	-1.0
Mineral and other dietary supplements	4.3	5.8	9.4	2.1	-1.7	-1.8	-1.9	-2.3	-2.1	-2.7	-3.0	-2.5	-2.5	-2.7	-2.7	-1.4	-2.9	-3.1	-2.5
Medication: Lansoprazole	4.1	4.6	13.2	0.8	2.8	2.9	2.8	2.4	2.9	3.6	0.8	2.9	1.2	1.3	2.3	1.9	0.4	1.2	-0.0
Angina	3.9	5.2	10.5	0.8	-2.3	-2.2	-1.9	-2.8	-2.5	-3.0	-1.9	-2.5	-2.1	-2.6	-3.2	-1.6	-2.0	-2.2	-1.5
Age when periods started (menarche)	3.8	9.1	26.3	-2.4	-5.1	-4.9	-4.7	-2.9	-4.8	-2.6	0.5	-3.2	-0.7	-0.3	-2.4	-2.3	1.5	-0.0	2.0
Angina (self-reported)	3.7	4.8	9.6	0.6	-2.3	-2.2	-1.9	-2.7	-2.5	-3.1	-1.7	-2.4	-2.0	-2.4	-3.1	-1.6	-1.9	-2.1	-1.4
Triglycerides	3.2	5.2	11.8	-1.5	-3.0	-3.3	-2.8	-2.2	-3.0	-3.4	-0.6	-3.2	-2.0	-0.9	-2.4	-2.1	-0.1	-1.0	0.2
Alzheimer’s Disease (including proxy)	3.0	4.3	13.1	-3.6	-1.3	-1.5	-1.3	0.8	-0.8	-1.0	2.5	0.0	2.5	2.6	1.5	-0.1	3.2	2.5	3.0
Exposure to tobacco smoke at home	3.0	3.4	9.8	0.3	2.6	2.6	3.1	2.2	2.6	1.5	1.1	1.7	1.4	1.7	1.8	1.6	0.6	1.2	0.2
Commuting to job workplace: Walk	3.0	3.2	5.3	-1.6	1.7	1.6	1.4	0.8	1.7	2.1	2.3	1.8	2.1	1.1	2.0	2.1	1.7	2.1	1.8
Commuting to job workplace: Public transport	2.7	3.2	6.6	-1.3	2.0	1.8	2.4	1.2	1.9	0.9	1.6	2.1	1.7	1.5	2.4	2.6	1.2	1.9	1.2
Medication: Atorvastatin	2.7	3.3	9.4	3.1	1.4	1.3	1.5	-1.1	0.8	0.6	-2.3	-0.5	-2.2	-2.3	-0.4	-0.1	-3.0	-1.9	-2.8
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	4.0	8.6	-1.0	2.2	2.1	1.7	2.5	2.5	1.4	1.6	2.7	1.9	2.9	2.4	0.8	1.5	2.1	1.0
Mean Putamen Volume	2.5	2.9	6.1	-0.8	1.7	1.7	1.3	2.5	2.0	1.7	1.5	1.6	1.8	2.4	1.9	0.5	1.6	1.8	1.1
Loneliness, isolation	2.5	3.5	9.0	1.4	3.0	2.9	3.0	1.5	2.8	1.9	-0.2	1.9	0.3	0.9	1.8	2.3	-0.7	0.5	-1.0
Pain type(s) experienced in last month: Hip pain	2.5	3.1	5.8	1.4	-1.1	-1.2	-1.2	-2.0	-1.4	-2.1	-2.2	-1.7	-1.8	-2.4	-1.8	-0.8	-2.2	-2.3	-1.5
Supplements: Fish oil (including cod liver oil)	2.5	3.2	5.6	-1.6	1.1	1.2	1.1	1.7	1.4	2.1	2.2	1.9	1.6	2.3	1.9	0.7	2.3	2.4	1.9
Number of children fathered	2.4	2.7	5.0	1.1	-1.5	-1.6	-2.1	-2.2	-1.7	-1.0	-1.8	-1.3	-1.9	-1.8	-2.2	-0.8	-1.6	-1.6	-1.4
Qualifications: College or University degree	2.4	7.6	15.7	-1.8	2.5	2.5	2.4	2.8	2.9	1.6	2.7	3.3	2.5	2.6	4.0	3.5	2.6	3.3	2.2
Schizophrenia (2014)	2.3	5.1	9.9	-1.5	2.4	2.2	1.7	2.8	2.7	2.2	2.2	2.2	2.1	2.9	3.1	0.7	2.1	2.6	1.6
Pain all over the body in last month	2.3	2.5	4.4	-1.7	1.1	1.1	1.0	1.7	1.4	0.4	2.1	1.8	1.7	1.7	1.8	1.1	1.9	2.0	1.9
Wheeze or whistling in the chest in last year	2.3	4.2	11.7	-2.0	1.3	1.1	1.5	2.6	1.6	0.5	2.2	1.3	2.6	3.4	2.0	1.6	2.5	2.6	2.1
Birth weight	2.2	4.8	10.4	1.0	-2.8	-2.4	-2.4	-2.3	-2.9	-1.4	-2.0	-3.2	-2.3	-1.6	-2.6	-1.9	-1.6	-2.1	-1.2
Suffer from ‘nerves’	2.2	3.4	6.6	-0.5	2.5	2.2	2.2	2.1	2.6	1.5	1.2	2.5	1.0	2.3	2.0	1.7	1.1	1.6	0.4
Schizophrenia (2018)	2.1	4.5	8.8	-1.6	1.8	1.8	1.2	2.5	2.2	1.8	2.5	1.8	1.9	3.0	2.9	0.4	2.3	2.6	1.9
Breast Cancer	2.1	5.1	14.5	-3.8	-0.9	-1.0	-0.6	0.9	-0.4	-0.2	3.2	0.6	2.4	2.8	1.5	0.8	3.7	3.0	3.8
Supplements: Glucosamine	2.1	2.8	6.5	-0.3	1.7	1.8	2.1	1.6	1.9	2.6	1.4	2.4	1.5	0.7	2.1	1.4	1.0	1.5	0.7
Financial difficulties in last 2 years	2.1	2.8	6.7	2.2	-0.2	-0.4	-0.3	-0.5	-0.4	-0.9	-2.5	-1.0	-2.1	-1.6	-1.8	-1.5	-2.4	-2.6	-2.5
Supplements: Vitamin C	2.1	2.5	9.6	-3.1	-1.2	-1.3	-1.2	0.6	-0.8	-1.2	2.1	0.1	1.3	1.5	0.6	0.1	2.5	1.6	2.5
Ever had hysterectomy (womb removed)	2.0	2.2	5.0	1.0	-1.0	-1.2	-1.6	-1.4	-1.3	-1.3	-1.6	-2.2	-2.0	-1.2	-1.7	-1.3	-1.4	-1.8	-1.2
Nervous feelings	2.0	3.8	6.6	-1.7	1.2	1.3	0.9	2.5	1.7	2.0	2.3	2.0	2.0	2.6	2.2	1.1	2.3	2.4	2.0
Noisy workplace	2.0	2.5	6.2	0.5	1.9	1.9	2.0	2.5	2.2	2.0	0.5	2.2	1.1	1.4	1.8	0.8	0.4	0.9	0.2
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.6	6.1	2.4	0.0	0.1	0.2	-1.3	-0.4	-1.1	-2.1	-1.3	-2.0	-1.9	-1.4	-0.5	-2.5	-2.1	-2.4
Medication: Ibuprofen	2.0	2.4	5.3	2.3	-0.2	-0.1	0.1	-1.2	-0.5	-1.1	-2.1	-1.3	-2.0	-1.8	-1.6	-0.4	-2.3	-2.0	-2.2
Had major operations	2.0	2.4	6.6	-1.6	-2.5	-2.6	-2.4	-1.0	-2.2	-1.3	0.5	-1.1	0.3	0.5	-1.5	-1.6	1.0	0.0	1.3
Bipolar Disorder or Schizophrenia	1.9	4.7	10.4	-0.1	3.0	2.9	2.3	2.9	3.2	2.0	1.5	2.5	1.2	2.3	3.0	0.8	1.2	1.9	0.7
Type 2 Diabetes (T2D) (2012)	1.9	2.2	5.7	-2.4	-2.1	-2.2	-1.8	-1.0	-2.1	-1.2	1.1	-1.4	0.6	0.0	0.2	0.6	1.3	0.9	1.8
Worrier / anxious feelings	1.9	3.6	6.5	-1.9	1.6	1.6	1.4	1.3	1.7	1.8	2.6	1.4	2.2	1.8	2.2	1.7	2.1	2.5	2.1
Unable to work because of sickness or disability	1.9	2.4	4.9	1.8	-1.1	-1.0	-1.3	-1.1	-1.0	-1.2	-1.9	-0.7	-2.2	-1.5	-1.4	-1.5	-1.9	-2.1	-2.0
Worry (Nagel 2018)	1.8	3.8	6.2	-0.7	2.2	2.2	2.0	1.9	2.4	2.5	1.7	2.5	1.7	2.1	2.1	1.7	1.5	2.0	1.1
Systolic blood pressure, automated reading	1.8	5.3	14.7	0.1	2.5	2.5	2.8	3.8	3.1	2.7	0.8	3.8	1.8	2.4	2.4	1.0	1.0	1.2	0.2
Medication: Atenolol	1.8	2.3	6.4	2.0	-0.3	-0.3	-0.2	-0.8	-0.4	-0.6	-2.3	-0.6	-1.7	-2.2	-1.1	0.0	-2.4	-2.0	-2.5
Number of incorrect matches in round	1.8	3.0	8.2	-2.8	-0.5	-0.4	-0.2	0.8	-0.2	0.4	2.5	1.0	2.3	2.3	0.9	0.7	2.7	2.2	2.9
Had other major operations	1.8	2.2	7.2	2.7	0.3	0.3	0.6	-0.3	0.2	0.1	-2.2	-0.5	-2.0	-1.6	-0.9	-1.0	-2.0	-2.0	-2.4
Hypertension (Self-reported)	1.8	5.0	11.8	2.2	3.3	3.1	3.4	2.4	3.4	1.3	-1.2	3.1	-0.0	0.4	1.7	1.3	-1.5	-0.4	-2.2
Risk taking	1.8	2.6	6.4	-2.3	-2.0	-2.3	-2.3	-1.7	-2.0	-2.5	0.9	-1.5	0.2	-0.2	-0.2	-1.5	1.2	0.5	1.3
Alzheimer’s Disease (in mother)	1.7	2.0	5.7	-2.4	-1.5	-1.6	-1.5	-1.1	-1.5	-1.2	1.5	-0.8	1.2	0.7	0.5	-0.4	1.8	1.2	2.0
Coronary Artery Disease (CAD)	1.7	2.0	5.8	0.5	-1.4	-1.3	-0.7	-1.9	-1.7	-1.2	-1.0	-2.4	-1.2	-2.0	-1.5	0.2	-1.3	-1.3	-0.9
Medication: Simvastatin	1.7	2.5	5.9	-0.9	-2.4	-2.4	-2.1	-2.1	-2.4	-1.7	-0.6	-1.3	-0.6	-1.4	-1.9	-0.4	-0.4	-0.9	0.0
Hypothyroidism (self reported)	1.6	3.6	11.0	2.9	1.8	1.4	1.4	-0.4	1.4	-1.1	-2.6	0.6	-2.0	-1.9	0.2	0.3	-3.0	-1.9	-3.3
High blood pressure	1.6	4.6	11.2	1.8	3.1	3.0	3.3	2.6	3.3	1.2	-0.8	3.2	0.2	0.7	1.9	1.4	-1.1	-0.0	-1.8
Hair/balding pattern: Pattern 2	1.6	2.1	6.1	-1.2	-2.5	-2.4	-2.3	-1.2	-2.3	-0.9	0.3	-1.2	-0.2	-0.4	-1.9	-0.6	0.7	-0.0	1.0
Asthma	1.6	3.1	6.0	-1.3	1.6	1.4	2.0	1.6	1.5	1.0	1.8	0.7	2.2	2.0	1.8	2.5	1.9	2.3	1.7
Comparative body size at age 10	1.6	4.5	13.0	3.4	1.3	1.2	1.2	-0.6	0.9	-0.2	-2.7	0.4	-1.8	-3.1	-1.4	0.9	-3.6	-2.8	-3.3
Medication: Bendroflumethiazide	1.6	2.4	5.6	2.0	2.2	2.1	2.4	0.7	2.0	1.5	-0.9	2.0	-0.2	-0.4	0.8	1.3	-1.5	-0.5	-1.7
Ever depressed for a whole week	1.6	2.0	6.3	-2.5	-1.6	-1.6	-1.8	0.2	-1.1	-0.7	1.5	-0.3	1.2	1.3	0.4	-0.3	2.0	1.4	1.9
Bipolar Disorder (2018)	1.5	2.3	6.1	1.8	2.5	2.4	2.1	1.5	2.4	1.1	-0.7	1.7	-0.5	0.0	1.1	0.8	-1.0	-0.2	-1.3
Blood Platelet Count	1.5	17.5	50.5	-3.6	-7.0	-7.1	-7.1	-1.9	-5.8	-5.3	0.7	-1.9	0.4	-0.0	-1.9	-5.5	2.6	-0.2	2.7
Trunk fat percentage	1.5	6.1	17.6	4.2	0.5	0.3	0.5	-1.0	0.1	-0.8	-3.9	-0.6	-3.2	-2.1	-1.3	-1.7	-3.9	-3.4	-4.0
Glaucoma (self-reported)	1.5	1.7	3.6	-1.9	-1.6	-1.9	-1.7	-1.8	-1.7	-1.9	0.7	-1.3	0.4	-0.8	-0.8	-0.5	0.6	0.3	1.2
Pulse wave peak to peak time	1.5	1.7	4.1	-1.7	0.0	0.2	0.3	1.3	0.3	1.3	1.9	0.6	1.5	1.8	0.8	0.8	2.0	1.8	1.8
Mouth/teeth dental problems: Loose teeth	1.5	1.8	4.2	1.2	-1.1	-1.2	-1.0	-0.4	-0.9	-2.0	-1.7	-0.4	-2.1	-1.2	-1.5	-1.3	-1.3	-1.4	-1.4
Average weekly red wine intake	1.5	2.3	5.2	-2.1	0.3	0.4	0.3	0.3	0.3	1.6	2.3	0.7	1.8	1.1	1.8	1.0	2.0	2.2	2.3
Back pain experienced in last month	1.5	2.1	5.5	-0.6	-2.3	-2.3	-2.0	-0.9	-2.1	-2.2	-0.3	-1.7	-0.5	-0.3	-0.9	-2.1	0.4	-0.5	0.6
Fractured/broken bones in last 5 years	1.5	1.9	4.8	-1.0	-2.1	-2.2	-1.5	-1.5	-2.2	-1.8	0.4	-2.2	0.3	-0.4	-0.8	-0.9	0.5	-0.0	0.9
Qualifications: A levels/AS levels or equivalent	1.4	3.0	11.4	-0.9	1.8	1.7	1.7	1.0	1.7	2.4	1.5	1.2	1.0	1.1	2.4	3.4	1.2	1.8	1.1
Pulse wave Arterial Stiffness index	1.4	1.6	3.5	1.5	-0.2	-0.3	-0.5	-1.4	-0.5	-1.4	-1.7	-0.6	-1.5	-1.7	-0.8	-0.8	-1.9	-1.7	-1.6
Birth weight of first child	1.4	2.5	5.1	-0.9	-2.1	-2.1	-2.2	-1.7	-2.2	-2.2	-0.4	-2.3	-0.9	-0.8	-1.1	-1.9	0.0	-0.8	0.4
Prostate Cancer	1.3	1.8	5.5	2.2	1.3	1.1	0.6	0.6	1.2	0.2	-2.1	0.8	-1.2	-0.8	0.0	-0.7	-2.0	-1.4	-2.3
Supplements: Zinc	1.3	1.5	3.0	-1.4	0.9	0.8	1.0	0.6	0.8	1.1	1.7	0.8	1.5	0.8	0.8	1.7	1.3	1.4	1.7
Diabetes (father)	1.3	1.7	4.9	-2.1	-1.3	-1.6	-1.4	0.6	-0.9	-2.2	1.1	-0.3	1.2	0.6	0.1	-1.5	1.5	0.8	1.5
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	4.8	0.7	1.6	1.6	1.4	1.1	1.6	1.2	0.3	1.6	0.3	0.8	2.2	0.7	-0.1	0.8	-0.2
Length of working week for main job	1.3	1.4	4.0	-2.0	-1.2	-1.3	-1.5	-0.8	-1.2	-1.0	1.3	-0.8	0.6	0.5	-0.2	0.1	1.6	1.1	1.9
Medication: Paracetamol	1.3	2.1	4.8	2.2	-0.1	-0.1	-0.3	-0.6	-0.3	-0.5	-2.1	-0.8	-1.8	-1.7	-1.6	-1.0	-2.1	-2.0	-2.2
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	3.3	-1.2	1.1	1.2	0.9	1.6	1.3	1.3	1.8	1.4	1.6	1.8	1.5	0.5	1.7	1.7	1.6
Medication: Blood pressure	1.3	2.5	7.2	2.6	1.6	1.4	1.7	1.0	1.6	0.2	-2.1	1.2	-1.1	-0.8	-0.4	0.4	-2.2	-1.7	-2.7
Medication: Paracetamol	1.3	2.0	4.4	1.8	-0.4	-0.3	-0.3	-1.1	-0.6	-0.6	-1.8	-1.1	-1.6	-2.0	-1.7	-0.8	-2.1	-2.0	-1.9
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	3.7	0.6	-1.2	-1.1	-1.1	-1.9	-1.5	-0.9	-1.1	-1.8	-1.1	-1.1	-1.3	-1.0	-1.3	-1.4	-0.9
Hearing difficulty/problems with background noise	1.2	1.9	5.3	-0.0	1.8	1.6	2.3	2.0	1.9	0.8	0.8	1.2	1.0	1.1	1.6	1.9	0.6	1.0	0.0
Father’s age at death	1.2	1.7	5.1	-2.2	-1.2	-1.2	-1.2	0.5	-0.7	-0.4	1.6	0.6	1.3	1.2	0.3	-0.3	2.0	1.3	2.1
Mouth/teeth dental problems: Dentures	1.2	1.9	5.1	-0.2	-1.3	-1.6	-2.0	-1.2	-1.4	-2.3	-1.2	-1.5	-1.2	-1.3	-1.7	-0.8	-1.2	-1.4	-0.8
Body fat percentage	1.2	4.5	15.4	3.9	1.0	0.8	1.0	-0.2	0.8	-0.3	-3.3	0.2	-2.6	-1.4	-0.5	-1.4	-3.4	-2.8	-3.5
Shortness of breath walking on level ground	1.2	1.4	3.5	1.1	-1.0	-0.8	-0.5	-0.9	-1.0	-1.4	-1.4	-1.4	-1.6	-0.9	-1.2	-1.9	-1.2	-1.2	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.5	0.5	1.6	1.7	1.8	0.9	1.5	1.9	0.4	1.2	0.7	1.0	0.8	1.5	0.2	0.7	0.1
Asthma (self-reported)	1.2	2.4	5.5	-1.2	1.5	1.3	1.9	1.3	1.4	0.7	1.6	0.4	1.9	1.6	1.6	2.4	1.6	2.0	1.5
Vascular/heart problems diagnosed by doctor	1.2	3.1	8.1	-1.7	-2.6	-2.5	-2.9	-1.9	-2.8	-0.7	0.9	-2.5	-0.0	-0.5	-1.3	-1.0	1.2	0.3	1.8
Cholesterol lowering medication	1.2	1.8	4.2	1.5	-0.4	-0.5	-0.5	-0.9	-0.6	-0.4	-2.1	-1.2	-2.0	-1.5	-1.0	-1.1	-1.8	-1.8	-2.0
Respiratory disease	1.1	2.5	4.3	-1.5	1.5	1.3	1.9	1.6	1.4	0.2	1.9	0.6	2.1	1.6	1.5	1.8	1.7	2.1	1.6
Medication: Co-codamol	1.1	1.3	3.3	1.5	-0.5	-0.5	-0.4	-0.3	-0.5	-1.4	-1.6	-0.5	-1.0	-0.8	-0.5	-1.8	-1.6	-1.5	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	4.3	0.2	1.8	1.7	1.3	1.8	2.0	-0.3	0.2	2.1	0.4	0.9	1.6	0.3	-0.0	0.7	-0.4
Migraine (self-reported)	1.1	1.3	4.2	2.1	1.2	1.3	1.3	0.9	1.2	0.1	-1.4	1.2	-0.7	-0.1	-0.4	0.3	-1.4	-0.9	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	10.1	-0.1	-1.3	-1.5	-1.9	-0.6	-1.3	-3.2	-1.1	-1.7	-1.7	-0.8	-1.8	-1.5	-0.7	-1.3	-0.6
Arm fat percentage (left)	1.1	4.3	15.4	3.9	1.0	0.9	1.2	-0.2	0.8	0.2	-3.2	0.4	-2.5	-1.3	-0.3	-1.3	-3.2	-2.7	-3.4
Medication for cholesterol	1.1	1.6	4.8	-1.8	-0.8	-0.6	-0.8	0.3	-0.6	0.6	2.0	0.1	1.5	1.2	0.6	0.2	2.0	1.7	2.2
Average weekly champagne plus white wine intake	1.1	1.5	4.7	-0.6	-2.0	-1.8	-1.7	-2.2	-2.1	0.3	0.1	-1.5	0.1	-0.8	-1.0	0.5	0.3	0.0	0.8
Heart attack/myocardial infarction (self-reported)	1.1	1.5	4.6	0.1	-1.3	-1.5	-1.3	-1.5	-1.6	-1.5	-0.8	-2.1	-1.2	-0.6	-1.7	-0.4	-0.4	-0.8	-0.4
Intelligence (Savage-Jansen 2018)	1.0	3.2	12.2	0.5	3.1	3.0	2.7	0.3	2.4	1.2	-0.1	0.4	-0.2	-0.1	1.5	3.5	-1.1	0.2	-1.2
Neuroticism (Nagel 2018)	1.0	2.3	6.0	0.5	2.4	2.2	2.2	1.6	2.4	1.2	0.1	1.7	0.6	0.6	1.6	2.0	-0.3	0.7	-0.5
Major Depression (MDD)	1.0	1.2	5.4	0.2	-0.8	-1.1	-1.1	-0.6	-0.8	-2.3	-0.6	-1.2	-1.1	-1.1	-0.9	-1.6	-0.7	-1.1	-0.5
HbA1C	1.0	1.1	3.7	-1.9	-0.9	-0.8	-0.3	0.3	-0.7	-0.8	1.4	-0.6	0.6	1.1	0.6	0.6	1.4	1.4	1.6
Cardiovascular Disease	1.0	3.3	8.7	1.4	2.7	2.5	3.0	2.0	2.8	0.7	-0.7	2.8	0.2	0.9	1.8	0.8	-0.8	0.1	-1.5
Chronotype (morning person)	1.0	2.3	6.7	-2.6	0.5	0.3	-0.1	0.0	0.4	1.0	2.5	0.4	2.0	1.3	1.0	1.1	2.1	2.2	2.4
Number of treatments/medications taken	1.0	1.8	4.6	0.2	1.9	1.7	2.1	1.0	1.8	1.2	0.5	1.7	0.9	0.9	1.8	1.8	0.0	0.8	-0.4
Heart attack	1.0	1.3	4.3	-0.2	-1.3	-1.4	-1.3	-1.4	-1.5	-1.4	-0.6	-2.1	-1.1	-0.3	-1.5	-0.4	-0.2	-0.6	-0.2
Allergy	1.0	2.3	4.9	0.3	-1.9	-1.9	-2.2	-1.8	-1.9	-1.2	-1.1	-0.9	-1.4	-1.3	-2.2	-1.8	-0.9	-1.4	-0.8
Prospective memory result	1.0	1.3	3.6	-0.8	0.6	0.9	0.7	1.3	0.8	1.9	1.4	0.8	1.3	1.3	0.8	0.6	1.4	1.4	1.3
Number of full brothers	1.0	1.3	3.3	-1.8	0.8	0.6	0.3	0.8	0.8	-0.0	1.5	1.3	1.4	1.6	0.3	0.6	1.5	1.3	1.4
Illnesses of siblings: Diabetes	1.0	1.2	3.1	-1.4	0.5	0.3	0.3	1.2	0.7	-0.2	1.5	1.4	1.3	1.8	0.8	0.2	1.6	1.3	1.2
Friendships satisfaction	1.0	1.3	3.3	0.6	1.8	1.7	1.2	1.3	1.7	1.3	-0.2	1.2	0.2	1.1	1.0	1.3	-0.2	0.4	-0.6
Eye problems/disorders: Glaucoma	1.0	1.2	3.1	-1.1	-1.3	-1.6	-1.6	-1.6	-1.4	-1.8	0.1	-0.8	-0.1	-1.1	-1.1	-0.7	-0.0	-0.4	0.5
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.8	-0.6	0.9	0.9	0.7	1.6	1.2	0.7	1.0	1.7	1.2	1.5	1.0	0.1	1.2	1.2	0.8
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	3.0	0.6	1.7	1.7	1.4	1.5	1.7	1.2	0.1	0.8	0.7	1.3	1.2	0.7	0.2	0.7	-0.2
Fasting Glucose	0.9	1.1	4.3	-1.6	-1.3	-1.5	-0.9	-0.6	-1.1	-2.1	0.6	-0.7	0.5	0.0	0.3	-0.7	0.8	0.4	1.1
Primary Biliary Cirrhosis	0.9	1.3	4.7	0.1	2.2	1.8	1.7	0.8	1.8	1.1	0.5	0.8	0.1	0.2	1.4	1.2	0.1	0.6	0.0
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.7	0.6	-0.9	-1.0	-0.9	-1.6	-0.9	-1.5	-1.0	0.1	-0.6	-1.6	0.3	-0.6	-1.1	-0.9	-0.9
Current tobacco smoking	0.9	1.4	3.0	1.3	-0.6	-0.6	-0.9	-0.3	-0.5	-1.4	-1.7	-0.6	-1.4	-1.3	-1.1	-0.9	-1.6	-1.6	-1.7
Trunk fat mass	0.9	3.7	12.2	3.5	0.9	0.7	0.9	-0.5	0.6	-0.4	-3.0	0.2	-2.5	-1.3	-0.5	-1.2	-3.1	-2.5	-3.1
Arm fat percentage (right)	0.9	3.4	12.2	3.5	1.1	1.0	1.2	-0.1	0.9	0.3	-2.8	0.7	-2.1	-1.0	-0.1	-0.9	-2.8	-2.3	-3.0
Impedance of arm (left)	0.9	4.3	7.8	0.9	-2.3	-2.1	-2.5	-2.0	-2.4	-1.9	-1.9	-2.8	-2.2	-1.9	-2.5	-1.7	-1.6	-1.9	-1.4
Age at last live birth	0.9	1.3	2.8	-1.6	0.0	0.0	-0.3	0.2	0.1	0.6	1.4	0.7	1.4	1.5	1.5	1.0	1.5	1.7	1.6
Qualifications: nursing, teaching	0.9	1.4	3.8	-1.9	-1.4	-1.3	-1.5	-0.5	-1.3	-0.6	1.2	-1.0	0.9	0.9	0.4	-0.4	1.6	1.1	1.6
Commuting to job workplace: Cycle	0.9	1.0	4.0	1.2	1.4	1.3	2.0	0.1	1.1	1.0	-0.5	0.2	-0.4	-0.7	1.1	1.1	-0.9	-0.1	-1.1
Depressed Affect (Nagel 2018)	0.8	1.7	4.6	1.2	2.1	1.8	2.2	0.6	1.8	-0.1	-0.8	0.7	-0.3	-0.3	0.9	2.0	-1.2	-0.1	-1.2
Schizophrenia vs Biploar Disorder	0.8	1.1	3.3	-1.3	-0.6	-0.5	-0.5	0.3	-0.4	0.4	1.4	-0.2	1.6	1.8	0.6	-0.8	1.6	1.2	1.4
Body Mass Index (BMI) (2010)	0.8	1.2	3.4	-0.4	1.3	1.1	1.3	1.1	1.4	0.9	0.8	1.8	0.8	1.0	1.1	0.8	0.8	1.1	0.7
Blood Red Count	0.8	8.1	31.7	2.3	4.2	3.7	2.8	5.6	4.7	0.9	-1.6	2.9	-0.4	2.9	1.6	-0.4	-0.7	-0.6	-2.7
BMI	0.8	4.5	11.9	2.2	3.4	3.1	3.4	1.5	3.2	1.7	-0.7	3.0	-0.2	0.5	2.3	0.9	-1.1	-0.1	-1.5
Waist Hip Ratio (WHR)	0.8	3.7	17.5	-2.2	-2.7	-2.9	-2.9	-1.6	-2.5	-4.2	-0.1	-1.7	-0.3	-0.2	-0.9	0.0	0.6	-0.1	0.8
Relative age of first facial hair	0.8	1.7	4.9	1.1	-1.1	-0.9	-1.0	-1.3	-1.4	-0.4	-1.2	-2.2	-1.2	-1.0	-1.7	-1.8	-1.2	-1.3	-1.0
Hayfever, allergic rhinitis or eczema	0.8	1.6	4.6	0.1	1.7	1.8	1.8	1.7	1.7	1.0	0.7	1.0	0.7	0.9	2.1	1.0	0.5	0.9	0.2
High blood pressure (mother)	0.8	1.1	2.7	-0.1	1.7	1.6	1.3	0.2	1.4	1.6	0.5	1.3	1.1	-0.2	1.0	1.4	-0.2	0.5	-0.1
Qualifications: None of the above	0.8	1.6	3.9	1.2	-0.8	-0.8	-1.2	-0.3	-0.7	-1.0	-1.7	-0.7	-1.4	-0.9	-1.5	-2.0	-1.4	-1.9	-1.6
Falls in the last year	0.8	1.1	2.6	-0.0	-1.5	-1.6	-1.3	-1.4	-1.6	-1.4	-0.5	-1.0	-0.7	-0.8	-0.8	-1.0	-0.3	-0.6	-0.0
Number of live births	0.8	1.1	3.2	-1.2	-0.1	-0.1	-0.3	1.8	0.5	-0.2	1.0	1.2	1.4	1.6	1.1	-0.4	1.4	1.2	1.0
Leg fat percentage (right)	0.8	2.8	9.7	3.1	1.4	1.2	1.4	0.9	1.4	-0.1	-2.4	1.0	-1.6	-0.3	0.3	-1.1	-2.3	-1.9	-2.7
Age at first live birth	0.8	1.5	4.8	-1.1	0.9	1.0	0.7	-0.0	0.8	1.4	1.6	1.0	1.0	0.9	2.2	1.3	1.2	1.6	1.3
Health satisfaction	0.8	1.0	1.9	-1.2	0.7	0.6	0.2	0.8	0.8	1.0	1.3	0.7	1.4	1.4	1.3	0.3	1.2	1.1	0.9
Medication: Seretide 50 evohaler	0.8	0.9	1.9	-1.2	0.5	0.3	0.7	0.2	0.4	-0.0	1.3	-0.2	1.1	1.1	1.3	1.2	1.2	1.4	1.2
Mood swings	0.8	1.5	4.0	2.0	1.2	1.1	0.9	0.8	1.1	-0.2	-1.7	-0.0	-1.5	-0.7	0.1	-0.3	-1.9	-1.2	-2.0
Hearing aid user	0.8	0.9	3.6	0.4	-0.5	-0.7	-0.8	0.9	-0.1	-1.9	-1.2	0.2	-0.8	0.1	-0.9	-1.9	-0.5	-0.9	-1.0
Average weekly beer plus cider intake	0.8	1.2	3.5	-1.2	0.8	0.6	0.7	1.4	0.9	-0.1	1.5	0.6	1.5	1.9	1.2	-0.2	1.3	1.1	1.0
Basal cell carcinoma (self-reported)	0.8	1.0	4.1	-0.2	0.2	0.5	0.9	1.4	0.4	2.0	0.9	0.1	0.9	1.4	0.9	0.6	1.2	1.0	1.1
Serious illness, injury or assault to yourself	0.7	0.9	2.6	-1.0	-1.4	-1.6	-1.1	-0.9	-1.4	-1.0	0.3	-1.0	0.1	-0.3	-0.3	-1.1	0.4	0.0	0.7
Body mass index (BMI)	0.7	3.0	10.2	3.2	1.8	1.6	2.0	0.6	1.7	0.7	-2.2	1.5	-1.4	-0.5	0.6	-0.4	-2.3	-1.7	-2.5
Medication: Ramipril	0.7	0.9	2.5	-0.2	1.3	1.4	1.6	0.7	1.3	0.7	0.5	1.1	0.8	0.1	0.4	1.5	0.1	0.4	-0.1
Neuroticism score	0.7	1.4	3.7	0.0	1.9	1.7	1.5	1.0	1.8	1.2	0.4	1.2	0.5	0.7	1.7	1.2	-0.0	0.8	-0.1
Hair/balding pattern: Pattern 3	0.7	1.0	2.1	0.2	1.3	1.3	1.4	1.4	1.4	1.1	0.6	0.8	1.0	1.4	0.6	0.9	0.4	0.7	0.0
Medication: Cholesterol lowering	0.7	1.0	3.0	-0.9	-1.4	-1.5	-1.3	-1.6	-1.4	-1.7	-0.1	-0.3	-0.2	-1.0	-1.0	0.1	-0.1	-0.2	0.3
Arm fat mass (right)	0.7	2.7	9.7	3.1	1.2	1.0	1.2	-0.0	1.0	0.3	-2.4	0.9	-1.9	-0.9	0.1	-0.7	-2.5	-2.0	-2.6
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	4.3	1.3	1.3	0.9	0.8	-0.1	1.1	-1.5	-1.3	0.6	-0.9	-1.1	0.4	0.5	-1.8	-1.0	-2.1
High blood pressure (siblings)	0.7	1.0	2.1	-0.6	1.4	1.4	1.2	0.9	1.4	0.1	0.9	1.4	1.2	0.8	0.8	0.9	0.4	0.9	0.4
Whole body fat mass	0.7	2.7	9.5	3.1	1.3	1.1	1.2	0.2	1.1	0.0	-2.4	0.8	-1.9	-0.7	0.1	-0.8	-2.5	-2.0	-2.7
Number of self-reported non-cancer illnesses	0.7	1.2	3.8	1.6	0.6	0.3	0.2	0.1	0.6	-1.1	-1.8	0.8	-1.3	-0.6	-0.5	0.3	-1.7	-1.2	-1.9
Mother’s age at death	0.7	0.9	2.5	-0.8	-0.1	0.2	0.7	1.0	0.2	1.6	1.3	0.6	1.1	1.0	0.5	-0.4	1.3	1.0	1.3
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.2	-1.5	-0.4	-0.5	-0.3	0.8	-0.1	-0.5	0.9	0.5	1.2	1.0	0.4	0.6	1.5	1.2	1.2
Leg fat percentage (left)	0.7	2.7	9.6	3.1	1.3	1.1	1.4	0.6	1.2	-0.2	-2.4	0.8	-1.7	-0.4	0.2	-0.9	-2.4	-1.9	-2.6
Verbal and Numeric Reasoning (VNR)	0.6	1.4	4.5	0.1	2.0	2.0	1.9	0.4	1.6	0.9	0.3	0.1	0.2	0.5	1.5	2.1	-0.3	0.4	-0.4
Age at First Birth	0.6	0.9	3.8	1.0	0.9	1.2	0.9	-0.5	0.5	1.7	-0.3	-0.3	0.2	-0.5	1.3	2.0	-0.8	0.1	-0.4
Rheumatoid Arthritis	0.6	0.8	1.8	-0.1	1.0	1.0	1.1	1.0	1.0	1.0	0.7	1.1	0.6	0.9	0.8	1.4	0.4	0.6	0.4
Hand grip strength (left)	0.6	1.6	4.2	-0.6	0.9	1.0	0.7	2.1	1.2	1.5	1.2	1.7	1.3	1.7	0.8	0.3	1.4	1.4	1.2
Waist circumference	0.6	2.0	5.9	2.4	0.6	0.3	0.6	-0.5	0.4	-0.9	-2.4	0.5	-1.8	-0.9	-0.1	-0.5	-2.4	-1.9	-2.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.9	-1.2	-1.0	-1.1	-1.4	-1.0	-1.0	-1.4	0.4	-0.7	-0.0	0.0	-0.4	-0.5	0.5	0.1	0.5
Fluid intelligence score	0.6	1.3	4.0	0.2	1.9	1.9	2.0	1.0	1.7	-0.2	0.2	0.4	0.3	0.5	1.6	1.2	-0.3	0.3	-0.4
Impedance of arm (right)	0.6	3.0	5.6	0.4	-1.9	-1.8	-2.4	-2.0	-2.1	-1.7	-1.4	-2.3	-1.7	-1.8	-2.2	-1.1	-1.3	-1.5	-1.1
Hip circumference	0.6	2.8	9.5	3.1	1.9	1.6	2.0	0.1	1.6	0.8	-2.1	1.1	-1.6	-0.6	0.5	-0.1	-2.3	-1.5	-2.4
Happiness	0.6	0.7	1.7	1.0	1.0	0.9	0.5	-0.7	0.6	0.5	-0.8	-0.5	-0.5	-0.8	0.3	1.3	-1.3	-0.6	-1.2
Hair/balding pattern: Pattern 4	0.6	1.6	3.5	-0.5	1.3	1.3	1.7	0.5	1.2	0.8	1.3	1.4	1.5	0.8	1.9	1.2	1.0	1.6	1.1
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.6	0.8	-0.4	-0.6	-0.5	-0.1	-0.3	-1.6	-1.1	0.3	-0.4	-0.4	-1.2	-1.2	-0.9	-1.2	-1.0
Overall health rating	0.6	1.3	4.1	1.8	0.5	0.2	0.2	-1.1	0.1	-0.7	-1.7	-0.6	-1.0	-1.4	-0.3	0.1	-2.0	-1.5	-1.9
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.9	0.3	1.2	1.4	1.3	1.0	1.3	0.1	0.2	0.8	0.2	0.7	0.9	1.0	0.0	0.6	-0.0
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.6	0.7	-0.4	-0.4	-0.7	-0.6	-0.4	-0.5	-1.1	-0.5	-0.9	-1.0	-0.4	-0.5	-1.3	-1.2	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.1	1.4	1.0	0.8	1.1	0.3	0.8	0.2	-0.8	0.2	-1.0	-0.7	0.4	0.3	-0.9	-0.5	-1.1
Eye problems/disorders: Cataract	0.6	0.7	3.0	-0.0	1.3	1.3	1.4	-0.1	0.9	1.7	0.5	-0.2	0.4	0.2	0.4	1.3	0.2	0.5	0.2
Arm fat mass (left)	0.6	2.5	9.2	3.0	1.3	1.1	1.4	0.0	1.1	0.5	-2.3	1.0	-1.7	-0.7	0.3	-0.7	-2.4	-1.8	-2.4
Financial situation satisfaction	0.6	0.7	2.1	-1.4	-0.7	-0.9	-0.8	-1.3	-1.0	-0.7	1.0	-1.2	0.4	0.3	-0.3	-0.3	0.9	0.5	0.9
Alcohol drinker status: Never	0.6	0.7	1.8	-1.3	0.4	0.3	0.1	0.3	0.3	1.2	1.2	0.6	0.9	0.6	0.4	1.0	1.0	1.0	1.1
Diastolic blood pressure, automated reading	0.6	2.0	4.3	1.6	2.0	2.0	1.8	1.8	2.1	1.3	-1.0	1.5	-0.5	0.3	1.0	0.4	-1.1	-0.7	-1.5
Myopia	0.6	0.9	2.5	1.0	0.5	0.3	0.1	-1.4	-0.1	-0.7	-1.0	-0.8	-1.4	-1.5	-0.4	0.4	-1.6	-1.1	-1.1
Pain experienced in last month	0.6	1.1	2.3	-0.4	1.1	1.2	0.9	1.1	1.2	1.5	0.9	1.3	0.6	0.8	1.1	1.3	0.8	1.2	0.5
Alcohol drinker status: Previous	0.6	0.7	3.7	-1.0	-0.8	-1.1	-1.3	0.1	-0.6	-1.9	0.1	-0.6	0.0	-0.0	-0.2	-1.3	0.3	-0.3	0.1
Impedance of whole body	0.6	3.1	6.2	0.2	-1.9	-1.9	-2.2	-1.6	-2.0	-2.4	-1.4	-2.5	-1.6	-1.5	-2.2	-1.4	-1.1	-1.5	-1.1
Depression (Nagel 2018)	0.5	0.8	2.2	1.1	0.4	0.3	0.0	-0.1	0.3	-1.0	-1.5	-0.5	-0.9	-1.3	-0.2	0.4	-1.5	-1.0	-1.4
Alzheimer’s Disease (in father)	0.5	0.5	1.6	-1.3	-0.3	-0.4	-0.1	1.0	0.1	-0.9	0.7	0.4	0.8	1.0	0.3	-0.6	1.0	0.6	0.8
Crohns Disease (2017)	0.5	1.2	3.5	1.9	0.7	0.9	0.3	-0.8	0.2	0.7	-1.1	-0.9	-1.0	-1.1	-1.0	0.2	-1.8	-1.5	-1.5
Systolic Blood Pressure	0.5	2.7	8.2	-1.0	1.1	1.0	1.7	2.9	1.7	0.9	1.1	2.5	1.8	2.5	1.7	0.2	1.5	1.3	0.8
Sensitivity / hurt feelings	0.5	0.8	2.1	-0.0	1.3	1.3	1.0	1.2	1.4	1.0	0.4	1.3	0.3	0.5	1.2	0.6	-0.1	0.6	-0.1
Medication for hormone replacement therapy	0.5	0.6	1.7	-1.3	0.1	-0.2	-0.1	0.1	-0.0	-1.1	1.0	-0.4	1.2	0.6	0.9	-0.1	0.9	0.8	1.2
Medication: Metformin	0.5	0.7	6.8	-0.6	-0.6	-0.9	-0.6	-0.1	-0.4	-2.6	-0.2	0.4	-0.1	-0.0	-0.0	-1.3	-0.0	-0.2	-0.2
Pack years adult smoking proportion	0.5	0.8	3.5	0.3	1.0	1.0	1.1	1.9	1.2	-0.2	0.2	0.6	0.6	1.7	0.5	-1.0	0.2	-0.0	-0.2
Hand grip strength (right)	0.5	1.4	3.1	0.1	1.6	1.7	1.1	1.8	1.7	1.6	0.6	1.2	0.6	1.3	1.1	0.6	0.6	1.0	0.3
Fed-up feelings	0.5	0.9	2.4	1.3	1.6	1.4	1.4	0.4	1.2	0.3	-0.8	-0.2	-0.5	-0.1	0.3	1.1	-1.2	-0.4	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.1	1.4	1.1	0.9	0.5	0.4	0.9	-0.2	-1.0	0.2	-0.5	-0.8	0.7	-0.2	-1.3	-0.7	-1.2
Taking other prescription medications	0.5	0.8	2.1	-0.6	0.8	0.6	1.0	0.8	0.9	0.6	0.7	1.5	1.3	0.9	1.3	0.7	0.6	0.7	0.2
Mouth/teeth dental problems	0.5	0.7	3.0	0.5	0.8	1.0	1.4	-0.1	0.6	1.7	0.3	0.3	0.4	-0.2	0.9	1.7	-0.1	0.4	-0.2
Trunk fat-free mass	0.5	2.7	5.3	-1.3	1.5	1.2	1.2	1.6	1.6	1.1	1.7	2.3	1.4	2.2	2.0	1.0	1.8	1.9	1.7
Time employed in main current job	0.5	0.5	1.7	-0.7	-0.4	-0.4	-0.4	0.6	-0.1	0.0	0.8	0.3	0.4	1.2	0.5	-0.5	1.3	1.2	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.7	0.1	-0.6	-0.8	-0.9	-1.2	-0.8	-1.3	-0.8	-1.2	-0.6	-1.6	-0.4	0.2	-1.0	-0.8	-0.5
Tense / ‘highly strung’	0.5	0.9	2.8	-0.2	1.1	1.0	0.5	0.8	1.1	1.2	0.5	1.0	0.6	1.7	1.4	0.7	0.7	1.1	0.5
Pulse wave reflection index	0.5	0.6	1.4	1.0	-0.1	-0.2	0.1	-0.8	-0.4	-0.8	-0.7	-0.6	-0.9	-1.2	-0.7	-0.9	-0.9	-1.0	-0.7
Headache pain in last month	0.5	0.9	3.1	1.2	0.2	0.3	0.1	-1.8	-0.4	-0.3	-1.1	-0.9	-1.4	-0.9	-0.4	0.7	-1.3	-1.0	-0.9
Gout (self-reported)	0.5	0.7	2.9	-0.4	-0.9	-1.2	-1.5	-1.7	-1.1	-1.1	-0.3	-0.6	-0.8	-0.3	-0.8	-0.2	-0.0	-0.1	0.2
Neck or shoulder pain in last month	0.5	0.8	1.8	-1.1	-1.2	-1.2	-1.3	-0.8	-1.2	-1.2	0.4	-1.1	0.4	-0.0	-0.0	-0.7	0.5	0.0	0.8
Leg fat mass (right)	0.5	2.1	7.2	2.7	1.4	1.2	1.5	0.7	1.3	0.1	-2.0	1.0	-1.4	-0.2	0.5	-0.9	-2.0	-1.6	-2.1
Number of full sisters	0.5	0.6	2.5	-1.2	-0.9	-1.0	-0.7	-0.2	-0.8	-1.6	0.6	-0.5	0.8	0.2	-0.4	-0.6	0.7	0.2	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	1.9	-0.6	0.5	0.5	0.1	1.4	0.8	-0.2	0.6	0.8	0.8	0.9	1.1	-0.2	0.7	0.8	0.3
Guilty feelings	0.5	0.7	2.3	-0.3	1.2	0.9	1.2	1.0	1.3	0.3	0.5	1.3	0.3	0.2	1.5	0.5	0.1	0.7	0.1
Wears glasses or contact lenses	0.5	0.6	3.3	0.3	1.0	0.9	0.6	0.4	1.0	0.4	-0.3	1.0	-0.2	-0.1	0.2	1.8	-0.5	0.1	-0.7
Ever smoked	0.5	1.0	3.0	0.1	-0.5	-0.7	-0.8	-1.5	-0.8	-1.7	-0.8	-1.5	-0.6	-0.9	-0.9	0.9	-0.9	-0.6	-1.0
Pack years of smoking	0.5	0.7	3.0	0.2	0.9	0.8	0.9	1.7	1.1	-0.3	0.3	0.6	0.6	1.7	0.5	-1.0	0.3	0.0	-0.1
Leg fat mass (left)	0.5	2.0	7.2	2.7	1.3	1.1	1.4	0.4	1.1	0.0	-2.0	0.8	-1.5	-0.3	0.4	-0.8	-2.0	-1.6	-2.1
Crohns Disease (2012)	0.4	0.6	1.9	0.5	-0.2	-0.0	-0.6	-1.4	-0.6	0.5	-0.4	-1.0	-0.8	-1.4	-1.0	0.1	-1.0	-1.1	-0.5
HDL Cholesterol	0.4	0.6	1.9	-0.4	0.3	0.5	0.7	1.4	0.6	0.9	0.7	0.8	1.0	0.6	1.1	-0.1	0.9	0.8	0.9
Hearing difficulty/problems: Yes	0.4	0.6	2.0	0.8	0.3	0.1	0.6	-0.7	0.1	-0.2	-0.9	-0.4	-1.0	-1.3	-0.2	0.9	-1.3	-0.8	-1.4
Maternal smoking around birth	0.4	0.6	1.7	0.6	1.1	0.9	1.1	1.3	1.2	-0.1	-0.1	1.3	0.5	0.4	0.6	-0.6	-0.3	-0.3	-0.5
Chronic bronchitis/emphysema (father)	0.4	0.4	1.4	-0.5	0.2	0.4	0.2	1.1	0.3	0.4	0.5	0.1	1.2	1.0	0.7	-0.7	0.7	0.5	0.6
Had menopause	0.4	0.5	2.3	-0.5	0.4	0.3	0.1	1.5	0.7	-0.2	0.4	1.0	0.6	1.0	0.8	-0.5	0.7	0.4	0.2
Diabetes (self-reported)	0.4	0.6	2.8	0.2	-0.4	-0.7	-0.7	-0.8	-0.5	-1.7	-0.7	0.0	-1.1	-0.8	-0.1	-1.2	-0.7	-0.8	-0.7
Illnesses of siblings	0.4	0.6	1.5	0.1	-1.2	-1.2	-1.1	-1.0	-1.2	0.1	-0.4	-1.0	-0.8	-0.4	-0.8	0.1	-0.0	-0.4	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	3.6	-1.9	-1.1	-1.2	-1.6	-0.6	-1.1	-1.6	0.8	-1.3	0.1	0.2	-0.2	0.4	1.1	0.7	1.2
Trunk predicted mass	0.4	2.5	5.0	-1.3	1.4	1.2	1.1	1.5	1.6	1.1	1.7	2.2	1.3	2.1	2.0	1.0	1.8	1.9	1.7
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.1	0.5	0.9	0.6	0.9	-0.0	0.8	-0.7	-0.4	0.7	0.3	-0.8	0.0	0.8	-1.0	-0.2	-1.0
Medication: Amlodipine	0.4	0.5	1.5	0.8	1.1	1.0	0.8	0.6	1.1	-0.2	-0.5	1.2	-0.1	-0.1	0.6	-0.2	-0.6	-0.3	-1.0
Exposure to tobacco smoke outside home	0.4	0.6	3.3	-1.0	-0.5	-0.9	-0.4	-0.6	-0.7	-1.8	0.4	-1.2	0.7	-0.1	-0.0	-0.3	0.4	0.1	0.5
Heart disease (mother)	0.4	0.4	1.4	-1.0	-0.0	-0.0	-0.2	0.8	0.3	0.8	0.9	0.6	0.6	0.4	1.2	-0.5	0.7	0.7	0.6
Chest pain or discomfort	0.4	0.6	1.4	1.1	-0.1	-0.1	0.4	0.5	-0.0	-1.1	-1.2	-0.4	-0.5	-0.2	-0.8	-0.5	-1.1	-1.0	-1.1
Leg pain on walking	0.4	0.4	1.7	0.1	-0.6	-0.7	-0.7	-1.2	-0.8	0.4	-0.5	-0.7	-0.4	-1.3	-0.2	-0.5	-0.5	-0.5	-0.3
Smoking status: Previous	0.4	0.6	2.3	-0.2	-0.4	-0.5	-0.6	-1.4	-0.7	-1.3	-0.4	-1.5	-0.4	-0.7	-0.4	0.6	-0.6	-0.3	-0.6
Long-standing illness, disability or infirmity	0.4	0.6	2.0	-0.8	0.6	0.4	0.9	-0.2	0.4	-0.2	0.9	0.1	1.1	0.7	0.9	1.4	0.6	1.0	0.5
Breast cancer (self-reported)	0.4	0.4	1.9	1.4	0.6	0.6	0.6	-0.5	0.4	0.8	-0.6	0.1	-0.7	-0.6	-0.3	-0.2	-0.8	-0.6	-0.8
Osteoarthritis (self-reported)	0.4	0.5	2.8	0.8	-0.6	-0.6	-0.6	0.6	-0.2	-0.6	-0.9	0.8	-0.6	-0.2	-0.4	-1.7	-0.4	-0.7	-0.8
Medication: Aspirin	0.4	0.6	1.8	0.2	-0.7	-0.6	-0.1	-1.3	-0.9	-0.7	-0.4	-1.0	-0.6	-1.2	-0.8	0.1	-0.9	-0.6	-0.5
Smoking status: Current	0.4	0.6	1.4	0.8	-0.3	-0.4	-0.7	0.1	-0.2	-1.0	-1.0	-0.1	-1.0	-0.7	-0.5	-0.6	-1.0	-1.0	-1.2
Miserableness	0.4	0.7	2.5	-0.1	1.6	1.3	1.2	0.5	1.3	-0.4	0.2	0.1	0.3	0.1	1.3	1.3	-0.3	0.6	-0.1
Irritable Bowel Disease (IBD)	0.3	0.7	2.2	1.5	0.7	1.0	0.5	-0.2	0.4	1.2	-0.9	-0.9	-0.2	-0.4	-0.3	0.7	-1.3	-0.8	-1.2
LDL Cholesterol	0.3	0.5	1.5	0.8	-0.1	-0.0	0.2	-1.1	-0.5	-0.2	-0.7	-1.2	-0.8	-0.8	-0.8	0.4	-1.0	-0.6	-0.8
Lupus	0.3	0.4	1.6	-0.8	-0.9	-0.5	-0.4	0.3	-0.6	0.2	0.4	0.0	1.2	0.9	0.0	0.5	0.9	0.7	0.7
Neuroticism (2016)	0.3	0.5	1.4	0.5	1.2	0.9	0.7	0.5	1.0	0.2	-0.6	0.4	-0.4	-0.3	0.8	0.8	-0.8	-0.2	-0.9
Ulcerative Colitis	0.3	0.4	1.4	0.7	-0.1	0.1	0.1	-0.4	-0.3	1.1	-0.7	-1.2	-0.4	-0.6	-0.2	0.5	-0.7	-0.4	-0.7
Heel T-Score	0.3	2.1	12.4	0.2	-1.4	-1.5	-0.1	-0.7	-1.3	-3.5	-0.8	-1.4	-0.9	-0.8	-0.8	-3.0	-0.7	-1.3	-0.5
Smoking Status	0.3	0.8	2.9	0.1	-0.6	-0.7	-1.3	-0.9	-0.6	-1.7	-0.8	-0.7	-0.8	-1.1	-0.4	-0.0	-0.9	-0.7	-1.0
Allergy or Eczema	0.3	0.8	2.8	0.4	1.4	1.3	1.3	1.4	1.3	0.6	0.3	0.5	0.2	0.4	1.7	0.6	0.2	0.4	-0.0
Type 2 Diabetes (T2D) (2018)	0.3	0.6	4.6	-0.3	-0.7	-1.0	-0.8	-0.2	-0.5	-2.1	-0.5	0.0	-0.5	-0.1	0.4	-1.1	-0.2	-0.3	-0.4
Neuroticism	0.3	0.8	2.4	0.7	1.6	1.3	1.2	0.5	1.4	0.8	-0.3	0.6	-0.3	-0.3	1.1	0.6	-0.8	-0.0	-0.8
Hair Pigment	0.3	7.7	15.2	2.9	-1.3	-1.3	-1.1	-2.0	-1.5	-2.4	-3.8	-2.0	-3.9	-3.4	-2.4	-2.6	-3.8	-3.8	-3.6
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.6	1.0	0.5	0.4	0.1	-0.5	0.2	0.2	-1.0	-0.3	-0.8	-1.0	0.1	0.5	-1.3	-0.7	-1.0
Impedance of leg (right)	0.3	1.4	4.7	-0.9	-1.5	-1.7	-2.0	0.1	-1.3	-2.2	-0.2	-1.1	-0.3	0.2	-1.2	-1.5	0.3	-0.4	0.1
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.2	-0.9	-0.4	-0.5	-0.3	0.2	-0.4	-1.1	0.6	-0.9	0.2	0.6	0.1	-0.4	0.7	0.5	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.1	-0.0	1.1	1.1	1.3	1.4	1.2	-0.3	0.4	0.9	0.4	1.1	1.1	-0.4	0.5	0.6	0.0
Stomach or abdominal pain in last month	0.3	0.4	1.3	-0.7	-0.7	-0.9	-1.1	-0.8	-0.8	-0.5	-0.0	-0.4	0.1	-0.8	-0.8	-0.0	-0.1	-0.3	0.4
Sitting height	0.3	2.3	9.9	-2.8	-1.2	-1.6	-1.4	-1.3	-1.3	-3.1	1.2	-1.2	0.1	0.5	-0.2	-0.6	1.3	0.9	1.9
Impedance of leg (left)	0.3	1.5	5.0	-0.7	-1.6	-1.7	-1.9	-0.4	-1.5	-2.2	-0.5	-1.6	-0.6	-0.3	-1.4	-1.2	-0.1	-0.6	-0.2
Past tobacco smoking	0.3	0.6	3.2	0.3	0.3	0.5	0.8	1.3	0.6	1.8	0.4	1.3	0.3	0.6	0.2	-0.9	0.6	0.2	0.8
Alcohol usually taken with meals	0.3	0.6	1.9	0.8	-0.6	-0.4	-0.7	-1.4	-0.7	1.0	-0.6	-0.7	-0.7	-1.2	-0.6	0.5	-0.6	-0.4	-0.4
Weight	0.3	1.4	4.6	2.1	1.1	0.9	1.1	0.3	1.1	-0.1	-1.6	1.0	-1.4	-0.2	0.4	-0.6	-1.6	-1.2	-1.7
Breastfed as a baby	0.3	0.4	1.8	-0.8	-0.1	0.0	0.1	1.3	0.3	0.3	0.6	1.2	0.4	0.8	0.3	-0.5	0.9	0.3	0.7
Loud music exposure frequency	0.3	0.4	1.2	0.6	0.2	0.1	0.2	-0.6	0.0	1.1	-0.6	0.2	-0.3	-0.9	-0.4	1.1	-0.7	-0.6	-0.7
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.0	-0.4	-0.8	-0.8	-0.9	0.2	-0.6	-0.4	0.3	0.2	0.2	0.9	0.1	-1.4	0.9	0.4	0.7
Eye problems/disorders: None of the above	0.3	0.3	0.9	-0.4	-0.9	-0.8	-1.0	0.2	-0.7	-0.5	0.1	-0.6	-0.3	0.8	-0.3	-0.4	0.5	0.3	0.5
Emphysema/chronic bronchitis	0.3	0.3	1.0	0.7	0.3	0.2	-0.0	0.3	0.3	-0.6	-1.0	-0.1	-0.3	-0.7	-0.4	0.0	-1.0	-0.7	-0.9
Alcohol intake frequency.	0.3	0.7	4.3	-0.2	0.3	0.3	-0.1	2.1	0.8	0.9	0.3	1.6	0.6	1.3	-0.3	-0.6	0.6	0.1	0.1
Medication: Aspirin	0.3	0.4	1.1	0.2	-0.5	-0.5	0.0	-1.0	-0.8	-0.7	-0.3	-0.9	-0.4	-1.0	-0.7	-0.1	-0.7	-0.6	-0.4
Diabetes diagnosed by doctor	0.3	0.5	1.4	0.7	0.5	0.2	0.3	-0.4	0.4	-1.1	-0.9	0.6	-0.9	-0.7	0.4	-0.2	-1.1	-0.7	-1.2
Osteoporosis (self-reported)	0.3	0.4	1.0	-0.4	-0.9	-0.7	-1.0	-0.2	-0.7	0.3	0.4	-0.1	0.9	0.8	0.1	-0.2	0.8	0.4	0.8
Medication: Lisinopril	0.3	0.4	1.1	0.7	1.0	1.0	1.0	-0.3	0.8	-0.0	-0.5	0.2	-0.4	-0.3	0.5	0.7	-0.8	-0.1	-0.9
Arm fat-free mass (left)	0.3	1.4	3.3	-0.4	1.5	1.2	1.4	1.1	1.5	0.8	0.9	1.8	0.9	1.4	1.7	0.9	0.8	1.1	0.8
Ulcerative Colitis (UC)	0.2	0.4	2.3	0.5	0.4	0.6	0.5	0.6	0.4	1.5	-0.1	-0.2	0.7	0.8	0.5	0.9	-0.0	0.2	-0.2
Ovarian Cancer	0.2	0.2	0.8	-0.7	0.3	0.1	0.2	-0.9	0.1	-0.5	0.6	0.1	-0.0	0.3	0.8	0.0	0.6	0.6	0.6
Bipolar Disorder (2011)	0.2	0.2	0.8	-0.6	-0.4	-0.4	-0.6	0.9	-0.1	0.1	0.4	0.4	-0.1	0.3	-0.1	-0.3	0.6	0.3	0.6
Blood Eosinophil Count	0.2	1.2	4.6	0.3	1.8	1.4	1.3	-0.0	1.5	0.7	-0.1	1.2	0.5	-0.6	1.2	2.1	-0.8	0.1	-0.6
Height	0.2	3.8	10.2	-2.5	1.2	1.1	0.6	2.1	1.4	-0.3	2.4	0.6	1.5	3.2	2.2	0.9	2.7	2.7	2.6
Lung FEV1/FVC ratio	0.2	1.1	5.7	-2.1	-0.8	-0.9	-2.4	-0.8	-0.8	-0.9	0.5	-1.0	-0.2	0.3	-0.3	1.3	0.7	0.5	0.7
Average weekly spirits intake	0.2	0.2	0.6	0.1	-0.8	-0.7	-0.5	-0.4	-0.7	-0.5	-0.4	-0.6	-0.3	-0.1	0.2	-0.5	0.0	-0.2	0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.9	-0.5	0.5	0.4	0.7	-0.2	0.3	0.3	0.5	-0.3	0.8	0.4	1.0	0.6	0.3	0.5	0.4
Diabetes (mother)	0.2	0.3	1.4	-0.7	-0.3	-0.4	-0.2	0.7	-0.1	-1.2	0.3	-0.4	0.4	0.4	0.0	-0.8	0.5	0.1	0.4
Severe depression (siblings)	0.2	0.2	1.2	-0.1	-0.5	-0.5	-1.1	-0.5	-0.6	0.4	-0.4	-0.4	-0.6	-0.3	-0.5	-0.1	-0.2	-0.5	-0.3
Townsend deprivation index at recruitment	0.2	0.3	1.5	-0.7	0.7	0.4	0.5	0.6	0.7	-0.7	0.3	0.1	0.0	1.2	0.4	0.6	0.6	0.5	0.2
Relative age voice broke	0.2	0.4	1.0	-0.6	0.1	0.1	-0.0	0.2	0.0	0.7	0.9	-0.1	0.9	1.0	0.0	-0.5	0.9	0.6	0.9
Medication: Levothyroxine sodium	0.2	0.4	1.1	0.4	0.8	0.6	0.5	0.9	1.0	-0.9	-0.4	0.7	0.1	0.1	0.4	0.1	-0.6	-0.2	-1.1
Pulse rate	0.2	0.3	2.7	-0.5	0.7	0.6	0.2	-0.5	0.4	0.2	0.2	0.1	0.2	0.1	0.3	1.6	0.0	0.2	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.7	-0.6	-0.1	-0.2	0.0	0.1	-0.1	-0.9	0.5	0.4	0.8	0.4	0.3	0.3	0.6	0.6	0.5
Depression (self-reported)	0.2	0.3	0.7	0.8	0.7	0.7	0.3	0.7	0.7	0.2	-0.5	0.1	-0.3	0.6	0.7	-0.4	-0.4	-0.2	-0.6
Illnesses of mother	0.2	0.3	1.2	0.6	0.5	0.7	0.7	0.5	0.5	1.0	-0.1	-0.0	-0.4	0.3	0.1	1.1	-0.0	0.1	-0.1
Peak expiratory flow (PEF)	0.2	0.5	2.1	-0.8	-0.7	-0.9	-0.8	-0.6	-0.9	-1.4	0.0	-1.2	-0.2	-0.2	-0.7	0.2	0.3	-0.1	0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.9	0.4	0.9	0.9	0.9	0.6	0.9	0.3	-0.1	0.4	-0.5	-0.4	0.5	0.8	-0.3	-0.0	-0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.0	0.8	0.7	0.7	0.4	0.9	0.6	1.0	-0.1	-0.3	0.0	0.5	-0.2	-0.4	-0.0	-0.2	-0.1
Worry too long after embarrassment	0.2	0.3	0.9	-0.9	0.1	0.1	-0.0	0.6	0.3	0.7	0.8	0.2	0.6	0.5	0.4	0.1	0.5	0.8	0.5
Medication: Blood pressure	0.2	0.4	0.9	0.5	0.6	0.6	0.9	-0.3	0.5	-0.2	-0.4	0.9	-0.3	-0.7	0.7	1.0	-0.8	-0.2	-0.9
Medication: Allopurinol	0.2	0.3	0.9	-0.8	-0.4	-0.7	-0.9	-1.0	-0.6	-0.4	0.4	-0.3	-0.0	0.1	-0.2	-0.1	0.6	0.3	0.7
Medication: Omeprazole	0.2	0.2	0.7	0.5	0.6	0.5	0.2	0.3	0.6	0.9	-0.2	0.3	0.3	0.3	0.7	0.4	-0.1	0.2	-0.3
Mean time to correctly identify matches	0.2	0.4	1.8	0.2	0.4	0.7	0.7	1.3	0.8	0.6	0.2	1.2	0.5	0.8	0.2	0.1	0.3	0.4	0.2
Pulse rate, automated reading	0.2	0.7	3.5	-0.8	-0.7	-0.8	-1.4	-1.9	-1.1	-0.8	-0.3	-0.9	-0.6	-0.5	-0.4	0.2	-0.3	-0.5	0.2
Family relationship satisfaction	0.2	0.2	1.6	-0.1	0.7	0.6	0.7	-0.3	0.4	0.1	0.2	-0.2	0.1	0.4	0.5	1.3	-0.1	0.4	-0.1
Whole body fat-free mass	0.2	0.9	2.1	-0.4	1.2	1.0	1.0	0.8	1.2	0.6	0.8	1.5	0.5	1.3	1.4	0.6	0.8	1.0	0.8
Ever had bowel cancer screening	0.2	0.2	1.3	0.2	-0.5	-0.3	-0.7	-0.5	-0.5	1.1	-0.2	-0.1	-0.0	-0.6	-0.4	-0.6	-0.2	-0.3	0.2
Whole body water mass	0.2	0.9	1.9	-0.4	1.1	0.9	1.0	0.8	1.1	0.6	0.8	1.4	0.5	1.2	1.4	0.6	0.8	1.0	0.8
Ever taken oral contraceptive pill	0.2	0.3	1.4	-0.2	0.1	0.0	-0.2	-1.2	-0.2	-0.3	0.2	-0.8	-0.3	-0.6	-0.2	1.2	-0.1	0.2	0.2
Number of operations (self-reported)	0.2	0.3	1.0	0.5	0.1	-0.2	-0.3	-0.0	0.0	-0.8	-0.5	-0.3	-0.8	0.1	-1.0	-0.7	-0.2	-0.6	-0.5
Irritability	0.2	0.3	1.9	0.3	-0.2	-0.4	-0.8	-0.0	-0.2	-1.4	-0.6	-0.3	-0.3	-0.3	-0.2	-0.9	-0.6	-0.6	-0.6
Age started oral contraceptive pill	0.2	0.2	0.8	-0.2	-0.2	-0.3	-0.8	-0.7	-0.3	0.3	-0.2	-0.1	-0.3	-0.9	-0.3	0.9	-0.2	-0.0	-0.1
Heart disease (siblings)	0.2	0.3	1.5	-0.3	0.9	0.7	0.6	0.0	0.8	0.7	-0.1	0.1	-0.1	-0.4	0.1	1.2	-0.3	0.2	-0.4
Arm predicted mass (left)	0.2	1.0	2.8	-0.4	1.3	1.0	1.1	1.0	1.3	0.6	0.7	1.7	0.8	1.2	1.4	0.7	0.7	0.9	0.7
Reaction Time	0.1	0.2	0.6	0.6	-0.3	-0.0	-0.1	0.8	0.1	0.0	-0.4	0.6	-0.1	0.1	-0.5	-0.8	-0.2	-0.3	-0.2
Tanning	0.1	0.7	2.8	-0.3	0.3	0.4	-0.5	1.7	0.8	-0.3	0.6	1.5	0.5	1.1	1.1	-0.5	0.9	0.9	0.4
Average weekly fortified wine intake	0.1	0.1	0.3	0.1	0.4	0.4	0.5	-0.1	0.3	0.0	-0.1	0.5	0.4	-0.1	0.0	0.3	-0.1	0.1	-0.2
Qualifications: CSEs or equivalent	0.1	0.1	0.8	0.0	-0.0	-0.2	0.0	-0.9	-0.3	-0.3	-0.1	-0.6	-0.0	0.0	-0.6	0.0	-0.1	-0.2	0.0
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	0.1	-0.3	-0.1	-0.3	0.5	-0.1	0.2	-0.2	-0.4	-0.2	0.3	0.2	-0.4	0.1	0.1	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.0	0.2	0.9	0.6	0.4	-0.3	0.6	0.4	-0.2	-0.1	-0.3	0.0	0.5	1.0	-0.4	0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.7	-0.1	0.2	0.2	0.3	0.5	0.3	-0.8	0.2	0.3	0.2	0.0	0.5	-0.6	0.1	0.1	-0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.3	0.2	-0.0	0.1	0.3	0.2	0.1	0.4	0.1	0.5	0.0	0.1	0.3	0.5	0.1	0.2	0.1
Alcohol intake versus 10 years previously	0.1	0.2	0.7	-0.1	0.5	0.3	0.4	-0.1	0.3	0.7	0.3	0.4	0.5	0.8	0.1	-0.4	0.4	0.4	0.3
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	1.1	-0.8	-0.1	-0.2	-0.7	-0.1	-0.2	-1.1	0.3	-0.5	-0.4	0.2	-0.1	0.2	0.5	0.2	0.5
Standing height	0.1	1.1	3.3	-1.8	-1.0	-1.2	-1.6	-0.5	-0.9	-1.7	0.8	-0.6	-0.2	0.5	-0.3	-0.3	1.1	0.7	1.3
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.1	0.1	-0.4	-0.3	0.1	1.1	0.0	-0.7	-0.4	0.2	0.0	0.4	-0.1	-0.5	0.1	-0.1	-0.3
Forced vital capacity (FVC), Best measure	0.1	0.4	1.7	-0.9	-0.7	-0.8	-1.0	-0.2	-0.6	-1.3	0.2	-1.0	-0.3	0.2	-0.1	-0.1	0.6	0.4	0.6
Arm fat-free mass (right)	0.1	0.6	1.5	0.0	1.2	0.9	1.1	0.9	1.2	0.2	0.3	1.2	0.3	0.8	1.2	0.3	0.2	0.4	0.2
Medication for pain relief, constipation, heartburn	0.1	0.2	0.7	-0.7	-0.3	-0.3	-0.3	0.3	-0.2	-0.1	0.6	0.2	0.5	0.4	0.2	0.1	0.8	0.5	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	0.3	-0.0	0.0	0.2	-0.3	-0.2	0.2	-0.2	-0.2	-0.4	0.2	-0.4	0.5	-0.1	-0.1	-0.0
Arm predicted mass (right)	0.1	0.5	1.4	-0.0	1.1	0.8	1.0	0.8	1.1	0.1	0.2	1.2	0.2	0.9	1.1	0.3	0.2	0.4	0.2
Comparative height size at age 10	0.1	0.4	1.3	-1.1	-0.2	-0.3	-0.4	0.8	0.1	-0.7	0.6	0.7	0.4	0.8	0.7	-0.0	0.9	0.8	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.3	-0.1	0.3	0.3	0.5	-0.2	0.2	0.5	0.3	0.4	0.5	0.1	-0.4	0.4	0.1	0.3	0.3
Illnesses of father: Heart disease	0.1	0.2	0.9	-0.7	0.3	-0.0	0.3	0.3	0.4	-1.0	0.4	0.2	0.2	-0.0	0.4	0.4	0.4	0.8	0.3
Medication: Gliclazide	0.1	0.2	0.6	-0.0	0.1	-0.1	0.3	-0.8	-0.2	-0.5	-0.2	-0.7	-0.2	-0.7	0.0	0.1	-0.5	-0.3	-0.3
High cholesterol (Self-reported)	0.1	0.2	0.6	-0.3	-0.7	-0.7	-0.3	-0.8	-0.8	0.1	0.1	-0.5	0.2	-0.1	-0.2	0.4	0.1	0.1	0.2
Basal metabolic rate	0.1	0.5	1.6	0.2	1.1	0.8	1.0	0.6	1.1	0.3	0.2	1.3	0.0	0.9	1.0	0.2	0.2	0.4	0.2
Lung FVC	0.0	0.2	0.7	0.8	-0.2	0.1	-0.3	-0.4	-0.2	-0.1	-0.6	-0.5	-0.6	-0.8	-0.1	-0.5	-0.6	-0.5	-0.6
Leg fat-free mass (left)	0.0	0.2	0.5	0.7	0.7	0.5	0.6	-0.2	0.5	0.1	-0.4	0.4	-0.6	0.1	0.5	-0.1	-0.5	-0.2	-0.3
Leg predicted mass (left)	0.0	0.2	0.5	0.7	0.7	0.5	0.6	-0.1	0.5	0.2	-0.3	0.4	-0.5	0.2	0.5	-0.1	-0.4	-0.1	-0.2
Forced vital capacity (FVC)	0.0	0.1	0.9	-0.1	0.2	0.1	-0.0	0.6	0.3	-0.9	0.1	0.0	-0.5	0.4	0.2	-0.4	0.4	0.2	0.1
Knee pain experienced in last month	0.0	0.1	0.2	0.2	-0.1	-0.2	0.0	-0.3	-0.2	-0.5	-0.3	-0.4	0.3	-0.1	-0.0	0.2	-0.3	-0.3	-0.2
Leg fat-free mass (right)	0.0	0.2	0.5	0.7	0.7	0.5	0.7	-0.4	0.4	0.1	-0.4	0.2	-0.7	-0.1	0.4	0.2	-0.6	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.6	-0.5	-0.2	-0.2	-0.8	0.3	-0.0	-0.1	-0.1	-0.2	-0.3	-0.3	-0.2	0.0	0.1	-0.1	0.0
Leg predicted mass (right)	0.0	0.2	0.6	0.8	0.6	0.5	0.7	-0.4	0.4	-0.0	-0.5	0.2	-0.7	-0.2	0.4	0.2	-0.6	-0.3	-0.4

Hub : Genes

SNX1

Models

Trait associations