Hub : Genes

RARRES1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1400	0.0340	2.6e-14	0.129	0.138	0.162	0.153	0.166	1.8e-15	1.9e-16	3.3e-19	3.4e-18	8.9e-20
2	GTEx	Brain Cerebellar Hemisphere	0.1580	0.0730	4.6e-03	0.298	NA	0.171	NA	0.272	2.3e-08	NA	3.7e-05	NA	1.1e-07
3	GTEx	Skin Not Sun Exposed Suprapubic	0.1490	0.0560	1.7e-03	0.086	NA	0.130	NA	0.147	1.9e-05	NA	1.4e-07	NA	1.9e-08
4	GTEx	Skin Sun Exposed Lower leg	0.1860	0.0530	7.2e-07	0.026	NA	0.052	NA	0.037	2.9e-03	NA	3.7e-05	NA	5.0e-04
5	TCGA	Bladder Urothelial Carcinoma	0.0620	0.0290	1.4e-04	0.030	0.046	0.055	NA	0.041	1.4e-03	8.8e-05	2.1e-05	NA	2.1e-04
6	TCGA	Colon Adenocarcinoma	0.2160	0.0920	1.3e-04	0.094	0.046	0.035	NA	0.069	4.4e-06	1.2e-03	4.2e-03	NA	8.5e-05
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0897	0.0408	2.6e-05	0.062	0.046	0.029	NA	0.054	1.8e-07	6.6e-06	2.7e-04	NA	1.1e-06
8	TCGA	Prostate Adenocarcinoma	0.0500	0.0282	1.6e-04	0.018	0.021	0.011	NA	0.009	5.3e-03	2.4e-03	2.1e-02	NA	3.3e-02
9	TCGA	Thyroid Carcinoma	0.0390	0.0230	4.7e-03	0.031	0.024	0.019	NA	0.018	5.3e-04	1.8e-03	5.4e-03	NA	6.6e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.3	2.1	5.1	-2.0	-1.8	-1.6	-1.3	-2.3	0.8	0.8	-0.5	-0.5
Bipolar Disorder or Schizophrenia	0.4	1.0	2.2	-1.1	-1.1	-1.5	-0.9	-1.4	1.0	1.0	-0.3	-0.2
Depressed Affect (Nagel 2018)	1.8	3.8	9.0	2.0	3.0	-0.6	0.9	1.3	1.5	1.5	2.8	2.4
Depression (Nagel 2018)	2.2	3.3	6.2	2.3	2.4	-0.8	0.7	1.9	1.5	1.5	2.5	1.6
Intelligence (Savage-Jansen 2018)	0.5	1.5	4.2	0.2	0.8	2.0	2.1	1.2	-1.1	-1.1	-0.3	-0.6
Neuroticism (Nagel 2018)	1.5	3.6	7.4	2.4	2.7	-0.3	1.2	1.6	0.8	0.8	2.7	2.6
Schizophrenia (2018)	0.1	0.1	0.4	0.2	0.1	-0.6	-0.1	0.0	0.6	0.6	-0.1	0.1
Schizophrenia vs Biploar Disorder	1.0	1.3	2.8	1.6	1.7	0.8	1.4	1.3	-0.6	-0.6	0.4	1.1
Worry (Nagel 2018)	1.6	3.3	6.5	2.5	2.4	-0.1	0.6	2.3	0.5	0.5	2.4	2.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.4	0.4	-0.1	-0.3	-0.5	-0.1	0.1	0.1	0.3	0.7
Alzheimer’s Disease (in father)	0.4	0.4	1.1	0.5	0.9	-0.2	0.1	0.4	0.5	0.5	0.8	1.1
Alzheimer’s Disease (including proxy)	0.3	0.5	2.0	0.9	0.7	-0.2	0.0	0.5	-0.0	-0.0	0.9	1.4
Crohns Disease (2017)	0.6	1.3	3.5	1.6	1.0	-0.0	-0.6	1.9	-0.5	-0.5	1.4	1.4
Irritable Bowel Disease (IBD)	0.8	1.9	5.2	1.6	1.6	0.2	0.6	2.3	-0.3	-0.3	1.8	1.7
Ulcerative Colitis (UC)	0.5	0.9	2.5	0.4	1.1	0.3	1.6	1.4	0.2	0.2	1.3	0.8
Major Depression (MDD)	0.2	0.3	0.6	0.6	0.7	0.4	0.3	0.7	-0.1	-0.1	0.8	0.1
Reaction Time	0.3	0.5	1.2	-0.1	-0.7	-1.1	-0.7	-0.9	0.7	0.7	0.2	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.4	0.5	1.0	0.6	1.2	1.0	0.0	0.0	0.5	0.6
Breast Cancer	0.5	1.1	4.5	0.1	0.5	-0.8	-0.2	0.0	1.0	1.0	2.1	1.6
Ovarian Cancer	2.0	2.6	6.9	2.3	2.3	-0.1	-0.1	1.7	0.9	0.9	2.6	1.3
Prostate Cancer	0.5	0.6	1.9	0.4	1.1	1.2	1.4	0.8	-0.4	-0.4	0.2	-0.5
Age at First Birth	0.9	1.3	3.2	-0.6	-0.8	0.9	0.9	-1.1	-1.8	-1.8	-1.2	-0.3
Bipolar Disorder (2011)	0.9	0.8	1.5	-1.2	-1.0	-1.1	-0.7	-0.8	0.9	0.9	-0.2	-1.1
Body Mass Index (BMI) (2010)	1.0	1.3	2.9	1.1	1.2	-1.1	-1.7	0.4	0.7	0.7	1.4	1.5
Coronary Artery Disease (CAD)	1.0	1.2	3.9	-1.0	-2.0	-0.9	-1.5	-1.0	-0.5	-0.5	-1.1	-0.3
Crohns Disease (2012)	0.2	0.4	1.3	0.2	-0.6	0.1	0.1	0.3	-1.2	-1.2	-0.4	0.1
Mean Putamen Volume	1.2	1.3	2.2	-1.4	-0.2	-1.2	-1.2	-1.5	1.5	1.5	0.6	0.0
Fasting Glucose	0.3	0.4	1.0	1.0	0.5	0.3	0.4	1.0	-0.6	-0.6	-0.4	-0.3
HbA1C	1.2	1.3	2.9	0.6	1.1	1.7	1.6	1.1	-1.2	-1.2	0.6	-0.3
HDL Cholesterol	0.1	0.2	0.9	-0.6	0.0	0.2	0.4	0.1	-0.0	-0.0	-0.3	-0.9
LDL Cholesterol	0.9	1.4	4.2	1.4	1.2	1.4	1.3	2.1	-0.5	-0.5	0.9	-0.3
Lupus	0.4	0.6	2.7	-0.1	-0.0	0.8	1.6	0.8	-0.7	-0.7	0.3	-0.8
Neuroticism (2016)	0.5	0.7	1.8	0.2	0.9	-0.7	0.0	-0.1	1.1	1.1	1.3	0.9
Primary Biliary Cirrhosis	1.2	1.7	4.8	1.2	1.6	-0.5	0.0	1.2	1.0	1.0	2.2	1.5
Rheumatoid Arthritis	0.1	0.1	0.4	-0.1	0.0	0.1	0.2	0.3	0.4	0.4	-0.4	-0.7
Schizophrenia (2014)	0.1	0.3	0.8	-0.3	-0.2	-0.9	-0.6	-0.3	0.7	0.7	-0.4	0.1
Triglycerides	1.2	2.0	6.1	1.6	1.8	0.8	1.4	2.5	-0.1	-0.1	1.9	0.0
Type 2 Diabetes (T2D) (2012)	1.6	1.8	6.0	2.1	1.3	-0.3	-0.0	1.6	-0.2	-0.2	1.2	2.5
Ulcerative Colitis	0.1	0.2	0.7	-0.9	-0.3	-0.5	0.2	-0.3	0.4	0.4	0.3	0.2
Blood Eosinophil Count	0.4	2.9	6.0	2.2	2.4	-0.2	0.5	1.7	0.5	0.5	2.4	2.3
Blood Platelet Count	0.1	1.2	2.8	-1.4	-1.7	-1.3	-1.2	-1.3	0.7	0.7	-0.1	0.3
Blood Red Count	0.2	1.9	4.5	-0.5	-1.1	1.3	1.0	-0.8	-2.1	-2.1	-1.8	-0.6
Blood White Count	0.2	1.1	2.7	-1.6	-1.4	0.2	0.7	-1.6	-0.6	-0.6	-1.1	-0.8
Heel T-Score	0.3	2.3	5.8	0.6	0.0	2.3	1.5	0.0	-2.4	-2.4	-0.7	0.5
BMI	0.1	0.4	2.0	0.3	0.0	-0.9	-0.9	-0.2	0.2	0.2	0.3	1.4
Height	1.5	28.1	47.5	-3.1	-4.0	6.2	2.3	-0.9	-6.9	-6.9	-6.4	-6.8
Waist Hip Ratio (WHR)	0.0	0.2	0.5	-0.2	0.3	0.7	-0.3	-0.1	-0.0	-0.0	0.4	-0.7
Systolic Blood Pressure	1.6	8.2	24.7	3.8	3.2	-1.6	0.9	2.8	1.4	1.4	3.1	5.0
Smoking Status	0.6	1.5	4.3	-0.1	0.8	-0.9	1.4	0.0	2.1	2.1	1.0	0.5
Allergy or Eczema	0.1	0.2	0.6	-0.2	0.3	-0.7	0.2	0.0	0.8	0.8	0.4	0.3
Cardiovascular Disease	1.3	4.3	13.9	2.7	1.7	-1.0	0.1	2.2	0.5	0.5	2.9	3.7
Hypothyroidism (self reported)	0.6	1.3	4.5	1.9	1.2	-0.3	1.2	0.8	0.1	0.1	0.6	2.1
Respiratory disease	0.8	1.8	3.7	-0.0	0.6	-1.9	-0.1	-0.3	1.9	1.9	1.2	1.9
Type 2 Diabetes (T2D) (2018)	2.2	4.1	11.5	2.2	1.4	-1.9	-0.8	0.2	2.0	2.0	2.5	3.4
Lung FEV1/FVC ratio	0.7	3.4	7.2	2.3	1.9	0.3	2.5	2.7	-0.2	-0.2	2.4	1.5
Lung FVC	3.0	15.1	36.8	-5.8	-4.4	-1.7	-2.4	-4.5	2.0	2.0	-3.1	-6.1
Neuroticism	1.7	4.1	8.3	2.1	2.7	-1.2	-0.1	1.4	1.7	1.7	2.9	2.8
Chronotype (morning person)	0.3	0.7	2.7	0.6	0.6	0.8	-0.9	1.6	-0.8	-0.8	0.5	-0.2
Hair Pigment	0.0	0.6	1.2	0.8	1.1	0.4	0.9	1.1	0.6	0.6	0.9	-0.3
Tanning	0.1	0.8	2.6	-1.5	-1.1	-0.5	0.3	-1.6	0.4	0.4	-0.3	-0.6
Hand grip strength (left)	1.2	3.1	8.5	-2.9	-2.0	-0.4	-1.1	-2.8	-0.2	-0.2	-1.9	-1.7
Number of treatments/medications taken	1.9	3.4	7.8	1.6	2.1	-1.1	0.8	1.6	2.0	2.0	2.8	1.8
Average weekly spirits intake	0.2	0.3	0.6	0.8	0.6	-0.1	0.5	0.8	0.3	0.3	0.6	0.0
Sensitivity / hurt feelings	1.9	3.3	6.2	2.2	2.4	1.3	2.5	2.5	-0.7	-0.7	1.6	1.3
Frequency of depressed mood in last 2 weeks	2.9	4.1	7.2	2.4	2.6	-1.3	0.1	1.8	2.1	2.1	2.7	1.8
Hearing difficulty/problems: Yes	0.2	0.3	1.2	0.7	0.4	-0.6	0.6	-0.6	0.2	0.2	0.3	1.1
Relative age of first facial hair	0.5	1.0	3.3	-0.1	0.3	-1.0	-1.8	-0.4	1.4	1.4	0.6	0.3
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.5	0.6	0.2	-0.1	0.4	0.7	0.4	0.4	-0.3	-0.4
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.3	0.4	-0.0	1.1	1.1	1.0	-0.6	-0.6	-0.2	-0.6
Ever had hysterectomy (womb removed)	1.0	1.1	2.9	-1.7	-1.5	0.2	0.4	-1.6	-0.5	-0.5	-1.2	-0.6
Systolic blood pressure, automated reading	0.5	1.3	7.0	1.7	0.7	-0.8	0.4	0.8	-0.2	-0.2	0.2	2.7
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.4	1.3	1.2	-0.7	-0.6	0.8	0.6	0.6	1.0	1.8
Angina	0.2	0.3	0.5	0.7	0.1	0.2	-0.6	0.7	-0.7	-0.7	0.3	0.5
Medication for hormone replacement therapy	0.8	0.9	2.7	1.0	0.9	1.1	1.6	1.5	-0.4	-0.4	-0.0	0.1
Vitamin and mineral supplements	0.2	0.3	1.0	0.7	0.4	-0.4	0.4	0.4	0.3	0.3	1.0	0.8
Supplements: Zinc	0.5	0.6	2.0	-0.1	-0.3	-1.1	-1.4	-0.3	0.8	0.8	-0.3	0.5
Medication: Co-codamol	0.4	0.5	1.5	0.7	0.9	0.7	0.9	1.2	0.0	0.0	0.8	-0.2
Medication: Metformin	1.8	2.5	9.5	1.9	1.3	-1.1	-0.0	0.3	0.9	0.9	2.1	3.1
Diabetes (father)	0.6	0.8	1.4	1.2	0.9	0.7	1.1	1.1	-0.7	-0.7	1.0	-0.0
Diabetes (mother)	0.3	0.4	1.4	0.5	-0.3	-1.1	-0.9	0.0	0.3	0.3	0.3	1.2
Severe depression (siblings)	0.9	1.0	3.3	0.9	1.4	-0.4	0.1	1.2	0.6	0.6	1.8	0.8
Pack years adult smoking proportion	1.0	1.6	4.7	0.0	0.2	2.2	1.4	0.9	-1.5	-1.5	-0.3	-1.4
Impedance of leg (right)	1.0	4.7	12.7	1.6	1.0	3.6	2.8	1.8	-2.3	-2.3	-1.1	-1.8
Leg fat-free mass (left)	0.1	0.8	2.2	-1.2	-1.5	-0.4	-0.9	-0.9	-0.7	-0.7	-0.8	-0.0
Trunk fat percentage	0.2	0.7	1.9	0.3	-0.6	1.2	-0.0	0.4	-1.4	-1.4	-0.7	-0.7
Hand grip strength (right)	1.5	4.2	10.8	-3.2	-2.3	0.0	-1.3	-3.3	-0.8	-0.8	-2.3	-1.7
Townsend deprivation index at recruitment	0.4	0.6	1.8	0.7	1.0	0.2	1.0	1.3	0.6	0.6	0.0	-0.0
Current tobacco smoking	1.0	1.7	4.2	0.7	1.6	0.3	2.1	1.9	1.1	1.1	1.5	-0.2
Average weekly fortified wine intake	1.4	1.6	4.3	0.6	0.2	1.6	1.5	1.1	-2.1	-2.1	0.1	-0.1
Maternal smoking around birth	0.3	0.5	1.2	0.2	1.1	-0.2	0.8	0.2	0.8	0.8	0.8	0.5
Fed-up feelings	2.4	4.4	11.5	2.5	3.4	-0.1	2.0	1.7	1.2	1.2	2.7	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	5.2	7.0	12.7	3.1	3.4	-1.6	0.5	2.4	2.6	2.6	3.6	2.6
Relative age voice broke	0.1	0.1	0.4	-0.1	-0.3	-0.0	-0.6	-0.2	0.0	0.0	-0.5	-0.4
Taking other prescription medications	1.4	2.1	4.5	1.7	1.8	-0.7	0.4	1.5	1.4	1.4	2.1	1.2
Age when periods started (menarche)	0.1	0.2	0.4	-0.4	-0.3	-0.1	-0.5	-0.0	0.4	0.4	-0.5	-0.6
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.2	-1.1	-1.2	0.7	0.5	-0.2	-0.9	-0.9	-0.9	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.7	-1.2	-1.1	-0.1	-1.1	-1.3	-0.1	-0.1	-0.7	-0.2
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.2	0.4	1.0	1.1	0.9	0.4	-0.0	-0.0	0.2	-0.0
Qualifications: CSEs or equivalent	2.8	3.7	7.3	2.7	2.7	-0.2	0.8	2.0	0.5	0.5	2.7	2.6
Serious illness, injury or assault to yourself	0.6	0.8	1.7	-0.9	-0.3	-1.2	-0.3	-1.1	1.3	1.3	-0.1	-0.1
High blood pressure	0.9	2.5	12.7	1.6	0.5	-1.6	-0.6	0.7	0.6	0.6	1.7	3.6
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.8	-0.0	0.4	-0.8	0.8	-0.2	0.9	0.9	0.7	0.6
Multivitamins +/- minerals	0.5	0.7	2.1	-0.4	-0.1	1.5	0.2	0.4	-1.0	-1.0	-0.6	-1.1
Stomach or abdominal pain in last month	2.6	3.3	7.0	1.9	1.4	-1.5	-0.4	1.8	1.5	1.5	2.6	2.6
Supplements: Glucosamine	0.6	0.8	1.9	-1.2	-0.8	0.6	0.8	-0.7	-0.9	-0.9	-0.7	-1.4
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	0.9	0.8	0.8	-0.9	-0.4	0.2	0.9	0.9	0.8	0.9
Medication: Atenolol	0.4	0.5	2.1	0.8	0.6	-0.4	-0.1	1.4	0.5	0.5	1.0	0.2
Medication: Levothyroxine sodium	0.2	0.3	1.4	0.6	0.5	0.1	1.2	-0.1	0.2	0.2	-0.3	0.8
Sitting height	0.6	4.1	8.0	-1.9	-2.3	1.4	0.5	-1.4	-2.1	-2.1	-2.7	-2.8
Chronic bronchitis/emphysema (father)	0.2	0.2	0.5	-0.1	-0.5	0.1	-0.7	-0.7	-0.4	-0.4	-0.6	-0.5
High blood pressure (mother)	1.9	2.7	8.7	2.4	1.6	-1.0	0.7	1.4	0.6	0.6	1.8	3.0
Body mass index (BMI)	0.2	1.1	3.0	-0.6	-1.2	-1.6	-1.7	-1.1	0.4	0.4	0.2	0.9
Impedance of leg (left)	0.8	4.0	11.2	1.9	1.3	3.3	2.5	1.8	-1.8	-1.8	-0.9	-1.6
Leg predicted mass (left)	0.2	0.8	2.2	-1.2	-1.5	-0.4	-0.9	-1.0	-0.7	-0.7	-0.9	-0.0
Trunk fat mass	0.2	1.1	2.4	-0.3	-1.2	0.9	-0.4	-0.3	-1.6	-1.6	-1.1	-0.8
Waist circumference	0.1	0.5	3.2	-0.2	-0.9	-0.7	-1.8	-0.5	-0.1	-0.1	0.1	0.3
Number of incorrect matches in round	0.9	1.4	2.3	1.5	1.2	-0.8	0.3	1.1	1.4	1.4	1.4	1.0
Past tobacco smoking	1.1	2.0	5.7	1.1	0.0	1.6	0.2	1.5	-2.4	-2.4	-0.5	-0.7
Alcohol usually taken with meals	0.4	0.6	1.3	1.0	0.3	1.0	0.6	0.7	-1.1	-1.1	0.2	0.3
Nervous feelings	0.8	1.6	3.3	1.5	1.8	-0.6	0.1	1.2	0.7	0.7	1.7	1.6
Frequency of tenseness / restlessness in last 2 weeks	4.5	7.1	16.4	2.8	3.2	-2.1	-0.5	2.3	2.6	2.6	4.1	2.4
Hearing difficulty/problems with background noise	1.0	1.7	5.8	-0.9	-1.0	-1.8	-1.1	-2.4	1.0	1.0	-0.1	0.8
Hair/balding pattern: Pattern 2	0.8	1.0	2.4	-0.1	-0.7	1.0	0.5	-0.5	-1.4	-1.4	-1.6	-0.8
Had menopause	3.1	3.8	8.7	-2.7	-3.0	0.5	-0.4	-1.6	-1.1	-1.1	-2.7	-2.4
Had other major operations	0.2	0.3	1.4	-0.3	-0.4	-1.2	0.0	-0.1	0.5	0.5	0.2	0.2
Forced vital capacity (FVC)	1.4	5.5	19.3	-3.5	-2.2	-0.4	-0.8	-2.2	1.1	1.1	-2.3	-4.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	1.6	-0.8	-0.9	-0.4	-1.3	-1.1	0.2	0.2	-0.5	0.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.8	-0.7	-0.1	-0.9	-0.4	-0.2	1.3	1.3	0.4	-0.4
Qualifications: None of the above	0.5	1.1	2.7	-0.0	0.1	1.4	1.6	1.2	-1.0	-1.0	-0.7	-1.3
Financial difficulties in last 2 years	0.2	0.3	0.5	0.7	0.6	0.6	0.4	0.7	0.1	0.1	-0.4	-0.6
Mouth/teeth dental problems	0.4	0.6	2.0	-0.6	-0.9	-0.0	-1.4	0.6	-0.5	-0.5	-0.1	-1.1
Heart attack	0.5	0.7	2.9	0.8	0.8	0.4	-0.2	1.3	0.1	0.1	1.7	0.6
Allergy	0.1	0.3	1.8	0.4	-0.3	0.2	-1.3	-0.1	-0.5	-0.5	-0.4	-0.1
Pain all over the body in last month	0.3	0.3	1.1	1.1	0.4	0.0	0.1	0.6	0.1	0.1	0.5	0.8
Diabetes (self-reported)	4.0	6.2	16.1	2.6	2.0	-2.2	-0.6	0.8	2.2	2.2	3.7	4.0
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	1.7	1.0	0.9	0.3	1.0	1.3	-0.4	-0.4	1.3	0.6
Medication: Ramipril	0.2	0.2	0.8	-0.7	-0.9	-0.6	0.2	-0.4	-0.2	-0.2	0.1	0.1
Medication: Simvastatin	0.6	0.9	3.4	0.9	0.3	-1.1	-0.7	0.5	0.4	0.4	1.2	1.8
Fluid intelligence score	0.2	0.5	1.1	-1.1	-0.7	0.6	0.7	-0.6	-0.7	-0.7	-0.8	-0.4
Illnesses of siblings	0.9	1.3	2.6	-0.3	-0.2	1.6	1.2	0.0	-1.3	-1.3	-1.6	-1.1
Neuroticism score	2.4	5.0	9.8	2.5	3.1	-1.0	0.9	1.6	1.7	1.7	3.1	3.0
Weight	0.3	1.4	3.5	-1.0	-1.9	0.3	-0.9	-0.9	-1.4	-1.4	-1.3	-0.7
Impedance of arm (right)	0.7	3.2	8.1	0.9	0.6	2.9	2.4	1.7	-1.9	-1.9	-1.0	-1.6
Arm fat percentage (right)	0.1	0.4	1.3	-0.3	-1.2	-0.1	-0.8	-0.5	-0.9	-0.9	-0.4	0.1
Trunk fat-free mass	0.3	1.6	3.3	-1.4	-1.8	0.3	-0.3	-1.4	-1.4	-1.4	-1.5	-0.4
Hip circumference	0.2	1.0	3.2	-0.7	-1.8	-0.4	-1.3	-0.6	-0.9	-0.9	-1.2	-0.1
Time employed in main current job	0.1	0.1	0.6	-0.3	0.2	0.8	0.3	-0.2	-0.4	-0.4	-0.2	-0.1
Alcohol intake versus 10 years previously	1.6	2.5	7.0	1.6	1.9	-0.9	0.2	1.5	1.4	1.4	2.6	1.2
Father’s age at death	1.1	1.5	3.5	-1.0	-1.8	0.0	-1.8	-0.9	-0.6	-0.6	-1.9	-1.2
Worrier / anxious feelings	1.2	2.2	5.6	2.0	2.0	-0.6	0.1	1.4	0.5	0.5	1.8	2.4
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	3.8	1.3	1.9	-1.2	1.0	0.5	1.9	1.9	1.7	1.8
Falls in the last year	1.0	1.4	3.1	0.9	1.4	-0.9	-0.2	1.8	1.2	1.2	1.7	0.6
Hair/balding pattern: Pattern 3	0.2	0.3	1.3	-0.7	-0.1	-0.2	0.2	-0.3	0.4	0.4	-0.5	-1.2
Number of live births	0.2	0.3	1.0	1.0	0.2	0.1	0.5	0.4	-0.5	-0.5	0.7	-0.0
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	12.2	-2.7	-1.8	-0.3	-0.3	-1.7	0.7	0.7	-1.8	-3.5
Pulse rate	0.5	0.9	2.5	0.3	-0.4	1.3	0.8	0.5	-1.6	-1.6	-0.5	-0.1
Happiness	0.9	1.1	2.4	-0.5	-1.1	-1.4	-1.5	-1.0	1.1	1.1	-0.4	-0.6
Noisy workplace	1.1	1.4	2.9	0.6	1.1	-1.2	-0.7	0.0	1.7	1.7	1.1	1.4
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.5	-1.2	-0.3	-0.7	-1.2	-1.1	0.9	0.9	0.4	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	2.1	-0.9	-1.4	-0.1	-1.0	-1.3	-1.2	-1.2	-1.2	-0.4
Mouth/teeth dental problems: Dentures	0.9	1.5	6.9	0.8	1.2	1.5	2.6	1.2	-0.7	-0.7	-0.1	-0.2
Asthma	1.4	2.7	5.8	-0.9	-0.2	-2.4	-1.6	-1.3	2.3	2.3	0.9	1.4
Medication: Ibuprofen (e.g. Nurofen)	3.1	3.9	8.2	2.0	2.2	-1.5	0.9	0.9	2.2	2.2	2.9	2.3
Medication: Cholesterol lowering	0.7	1.1	3.5	0.5	-0.0	1.4	0.6	0.8	-1.9	-1.9	0.1	-0.0
Depression (self-reported)	0.0	0.0	0.1	0.1	-0.0	0.3	0.0	0.0	-0.1	-0.1	-0.2	-0.3
Medication: Lansoprazole	0.4	0.5	1.8	0.6	1.0	0.7	1.4	-0.2	0.2	0.2	0.0	0.8
Prospective memory result	0.4	0.5	1.4	0.2	-0.1	-1.2	-1.0	-0.2	0.8	0.8	0.4	0.9
Lung cancer (father)	2.0	2.3	6.1	-2.5	-2.2	-0.3	-1.2	-1.9	-0.6	-0.6	-1.3	-1.4
Illnesses of mother	1.0	1.3	3.6	-1.9	-0.9	-0.8	-1.1	-1.5	0.7	0.7	-0.5	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	9.1	-2.5	-1.7	-0.2	-0.4	-1.9	0.5	0.5	-1.7	-3.0
Pulse wave Arterial Stiffness index	0.4	0.5	1.2	0.9	0.7	0.0	0.9	1.1	0.5	0.5	0.4	0.2
Impedance of arm (left)	0.8	3.5	8.9	1.2	1.0	3.0	2.5	2.2	-1.7	-1.7	-0.7	-1.7
Arm fat mass (right)	0.1	0.6	1.7	-0.5	-1.3	0.0	-0.8	-0.7	-1.0	-1.0	-0.7	0.0
Trunk predicted mass	0.3	1.7	3.6	-1.5	-1.9	0.3	-0.4	-1.5	-1.4	-1.4	-1.6	-0.5
Standing height	0.9	8.5	16.0	-1.1	-1.8	3.9	1.7	0.0	-4.0	-4.0	-3.4	-3.2
Length of working week for main job	1.7	1.9	4.7	1.5	1.5	1.6	1.9	2.2	-0.8	-0.8	0.3	0.2
Exposure to tobacco smoke at home	0.3	0.4	1.0	-0.5	0.4	0.6	1.0	1.0	-0.1	-0.1	0.5	-0.4
Breastfed as a baby	0.5	0.6	0.8	-0.5	-0.8	0.6	0.8	-0.8	-0.8	-0.8	-0.9	-0.6
Tense / ‘highly strung’	2.0	3.3	7.4	2.0	2.4	-0.6	0.4	2.1	1.4	1.4	2.7	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.8	0.5	0.9	0.4	0.7	0.2	0.2	0.2	-0.1	-0.1
Hair/balding pattern: Pattern 4	0.5	1.3	3.1	1.2	0.8	-1.0	-0.9	0.6	1.0	1.0	1.5	1.8
Birth weight of first child	0.2	0.4	1.3	-1.0	-0.1	-0.1	-0.8	-0.1	0.5	0.5	0.0	-1.1
Peak expiratory flow (PEF)	0.3	0.7	1.0	-0.6	-0.7	0.8	1.0	0.0	-1.0	-1.0	-0.9	-0.9
Pulse wave reflection index	0.4	0.5	1.3	0.3	0.6	-0.7	0.2	0.3	1.1	1.1	0.3	0.6
Ever highly irritable/argumentative for 2 days	2.4	2.9	4.5	1.8	1.8	-1.1	-1.3	1.7	2.0	2.0	2.1	0.8
Loud music exposure frequency	2.2	2.4	4.5	-1.2	-0.4	-2.1	-1.5	-1.9	2.0	2.0	0.8	0.9
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.7	-0.2	0.4	0.1	0.5	0.0	0.4	0.4	0.9	0.4
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.4	0.9	1.0	0.4	0.3	0.0	-0.1	-0.1	0.3	1.2
Blood clot in the leg (DVT)	1.2	1.5	3.2	-1.4	-1.4	0.8	1.1	-1.2	-1.2	-1.2	-1.8	-0.9
Medication: Paracetamol	1.5	2.5	5.4	1.0	1.5	-1.5	0.3	0.5	2.1	2.1	2.3	1.6
Headache pain in last month	7.6	13.0	29.1	5.2	5.4	0.3	2.8	4.6	1.3	1.3	4.2	3.5
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.3	-1.4	-0.8	-0.5	-0.6	-1.3	0.9	0.9	-1.2	-1.8
Glaucoma (self-reported)	0.3	0.4	1.4	-0.9	-1.2	-0.4	-0.3	-0.5	-0.1	-0.1	-0.6	-0.5
Gout (self-reported)	0.4	0.6	2.2	-1.1	-0.4	-0.3	-0.4	-1.5	-0.2	-0.2	-0.9	0.6
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.6	1.0	0.8	-1.0	0.6	-0.3	1.1	1.1	0.5	1.6
Medication: Amlodipine	0.8	1.2	3.2	-0.7	-0.9	-1.8	-1.1	-0.8	1.2	1.2	0.4	1.0
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.1	0.4	0.9	-0.9	-1.2	0.7	1.4	1.4	1.8	0.7
Birth weight	1.7	3.7	6.8	-2.4	-2.3	0.9	-0.5	-2.2	-1.4	-1.4	-2.5	-2.6
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.4	0.8	0.3	0.1	0.3	1.2	0.5	0.5	0.8	0.0
High blood pressure (siblings)	1.1	1.6	4.6	-0.1	-0.5	-2.1	-1.6	-0.6	1.4	1.4	0.9	1.4
Forced vital capacity (FVC), Best measure	1.3	4.7	13.7	-3.2	-2.2	-0.4	-1.0	-2.4	0.8	0.8	-2.4	-3.7
Body fat percentage	0.1	0.5	1.5	0.2	-0.8	0.8	-0.3	0.1	-1.2	-1.2	-0.6	-0.4
Leg fat percentage (right)	0.1	0.3	1.1	0.1	-0.8	0.1	-1.1	-0.4	-0.6	-0.6	-0.2	-0.1
Arm fat-free mass (right)	0.2	0.9	2.1	-1.0	-1.5	0.2	-0.7	-1.0	-1.0	-1.0	-1.1	-0.5
Exposure to tobacco smoke outside home	1.0	1.3	3.0	-0.8	-0.2	-1.6	-1.2	-0.5	1.7	1.7	0.8	0.4
Comparative body size at age 10	0.1	0.3	1.2	0.2	-0.5	-0.8	-0.5	-0.4	0.4	0.4	-0.3	1.1
Number of full brothers	0.9	1.2	1.7	1.2	1.3	-0.9	0.6	1.2	1.2	1.2	0.9	1.2
Worry too long after embarrassment	0.1	0.2	0.5	0.5	0.2	-0.3	0.7	0.2	0.3	0.3	0.5	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	0.4	0.3	-0.4	-0.4	-0.2	0.5	0.5	0.1	0.4
Wheeze or whistling in the chest in last year	1.7	3.1	6.6	0.6	1.6	-1.8	-0.5	0.7	2.5	2.5	2.6	1.4
Number of children fathered	1.2	1.4	4.0	-0.1	-0.8	1.6	0.7	-0.2	-2.0	-2.0	-0.8	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.5	5.4	-2.0	-2.3	0.5	-0.7	-1.5	-1.3	-1.3	-1.8	-1.8
Age at first live birth	0.7	1.3	3.0	0.9	1.3	1.6	1.7	1.4	-0.9	-0.9	0.6	0.2
Pulse wave peak to peak time	0.5	0.6	1.2	-1.0	-0.8	0.3	-0.8	-1.1	-0.9	-0.9	-0.6	-0.4
Health satisfaction	0.4	0.5	1.3	0.2	0.2	-0.9	0.2	-0.1	0.9	0.9	1.1	0.5
Shortness of breath walking on level ground	1.4	1.6	3.1	1.3	1.6	-0.6	1.3	0.9	1.4	1.4	1.8	0.9
Qualifications: College or University degree	1.3	4.0	7.8	-1.9	-2.7	1.0	-0.1	-2.2	-2.2	-2.2	-2.8	-1.3
Eye problems/disorders: None of the above	0.1	0.1	0.3	0.3	-0.1	0.5	0.2	0.2	-0.5	-0.5	0.2	-0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.4	2.6	0.0	-0.6	-0.1	-0.1	-0.5	-0.1	-0.1	-1.6	-0.1
Emphysema/chronic bronchitis	0.3	0.3	2.4	-0.1	0.3	0.3	1.5	0.1	0.2	0.2	0.2	-0.3
Medication for pain relief, constipation, heartburn	1.5	2.5	6.5	-1.4	-1.5	0.6	-1.3	-1.7	-1.8	-1.8	-2.6	-0.5
Neck or shoulder pain in last month	2.3	3.3	7.0	2.1	2.5	0.5	1.9	2.4	1.2	1.2	2.6	-0.0
Medication: Blood pressure	1.0	1.8	4.9	1.6	1.2	-0.9	0.0	1.6	0.8	0.8	1.7	2.2
Angina (self-reported)	0.2	0.3	0.8	0.5	-0.1	0.4	-0.5	0.6	-0.9	-0.9	0.0	0.2
Migraine (self-reported)	0.9	1.1	2.7	1.6	1.2	0.5	0.7	1.5	-0.5	-0.5	0.7	1.3
Medication: Ibuprofen	3.7	4.4	9.2	2.5	2.9	-0.9	1.4	1.6	1.7	1.7	3.0	2.2
Medication: Allopurinol	0.2	0.3	0.9	-0.6	-0.2	0.3	0.3	-0.9	-0.4	-0.4	-0.9	0.6
Medication: Omeprazole	0.8	1.0	2.7	0.9	0.7	1.1	1.2	1.7	-0.5	-0.5	0.8	-1.1
Medication: Seretide 50 evohaler	2.1	2.5	7.1	-0.3	0.5	-1.9	-1.0	-0.8	2.7	2.7	1.3	0.9
Mean time to correctly identify matches	0.3	0.5	1.2	-0.7	-1.1	-0.4	-0.9	-1.1	0.3	0.3	-0.6	-0.4
Heart disease (mother)	0.5	0.6	1.5	0.6	0.5	1.2	0.7	1.2	-0.6	-0.6	-0.3	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.5	-0.0	-0.2	0.1	-0.2	-0.8	-0.8	-0.8	-0.2	1.6
Whole body fat mass	0.2	1.0	2.1	-0.4	-1.4	0.6	-0.7	-0.6	-1.4	-1.4	-1.0	-0.5
Leg fat mass (right)	0.2	0.6	1.6	-0.3	-1.2	-0.1	-1.2	-0.8	-0.8	-0.8	-0.6	0.0
Arm predicted mass (right)	0.3	1.3	2.9	-1.4	-1.7	-0.2	-1.0	-1.6	-0.7	-0.7	-1.3	-0.5
Pulse rate, automated reading	0.1	0.4	1.0	0.4	-0.5	0.5	0.4	-0.0	-1.0	-1.0	-0.3	0.5
Alcohol intake frequency.	0.7	1.6	3.1	1.1	1.0	-1.6	-0.2	0.5	1.2	1.2	1.7	1.8
Comparative height size at age 10	0.6	3.2	6.6	-1.1	-1.0	2.4	1.2	0.5	-2.0	-2.0	-2.1	-2.6
Number of full sisters	0.8	1.0	3.2	1.8	0.7	0.0	0.3	1.3	0.0	0.0	1.4	1.2
Suffer from ‘nerves’	1.0	1.6	3.5	1.8	1.6	0.6	1.1	1.9	-0.1	-0.1	1.5	1.0
Overall health rating	0.9	1.8	3.3	1.4	1.5	-1.0	0.3	0.7	1.4	1.4	1.8	1.8
Chest pain or discomfort	1.6	2.3	7.0	1.4	1.2	-1.6	-0.2	0.6	1.3	1.3	2.1	2.6
Had major operations	1.2	1.4	2.4	0.9	1.5	-0.9	-0.3	0.4	1.5	1.5	1.5	1.3
Age at last live birth	1.0	1.4	3.0	1.3	1.7	1.1	1.5	1.6	0.0	0.0	1.3	-0.1
Family relationship satisfaction	0.8	1.0	2.3	-1.3	-1.1	-0.7	-1.2	-1.5	0.4	0.4	-0.6	-0.9
Leg pain on walking	0.5	0.6	1.5	1.0	1.2	0.3	0.5	0.6	0.0	0.0	1.2	0.6
Qualifications: NVQ or HND or HNC or equivalent	2.6	3.2	5.7	0.8	1.2	-2.4	-1.6	-0.4	2.1	2.1	1.9	2.4
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.2	1.1	0.6	0.1	-0.1	0.8	0.0	0.0	1.0	0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.5	0.2	0.7	0.3	0.5	0.7	0.1	0.1	0.3	-0.0
Medication: Aspirin	1.9	2.5	6.9	1.7	1.7	-0.6	0.4	2.0	1.5	1.5	2.6	0.8
Supplements: Vitamin C	0.9	1.1	2.9	-0.4	-0.2	-1.3	-1.7	-1.0	1.4	1.4	0.0	0.4
Knee pain experienced in last month	0.1	0.2	0.5	-0.0	0.4	-0.2	0.2	0.2	0.7	0.7	0.7	-0.6
Hypertension (Self-reported)	1.1	2.9	13.7	1.7	0.6	-1.8	-0.7	0.8	0.9	0.9	1.8	3.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.8	0.8	0.4	-0.6	-0.5	0.1	0.9	0.9	0.3	0.4
Illnesses of father: Heart disease	0.7	1.0	2.2	-0.6	-1.4	-1.4	-1.2	-1.5	0.2	0.2	-0.4	0.6
Illnesses of siblings: Diabetes	0.4	0.5	2.3	0.7	0.7	0.3	0.1	1.5	0.5	0.5	0.8	-0.1
Smoking status: Previous	2.1	3.1	6.4	-1.5	-0.5	-2.1	-1.2	-2.5	2.5	2.5	0.1	0.8
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.2	10.4	-0.0	0.2	3.2	2.3	1.1	-2.8	-2.8	-1.2	-1.9
Whole body fat-free mass	0.2	1.2	2.8	-1.3	-1.7	0.0	-0.6	-1.3	-1.1	-1.1	-1.2	-0.2
Leg fat-free mass (right)	0.1	0.8	2.1	-1.2	-1.5	-0.6	-1.1	-1.0	-0.5	-0.5	-0.8	0.1
Arm fat percentage (left)	0.1	0.3	1.2	-0.2	-1.1	-0.2	-0.8	-0.3	-0.7	-0.7	-0.2	0.0
Average weekly red wine intake	2.4	3.6	6.1	-2.0	-2.5	1.4	0.7	-0.9	-2.0	-2.0	-2.3	-2.3
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.9	-0.8	-0.4	-0.9	-0.8	-0.2	0.5	0.5	0.4	0.0
Mood swings	2.1	3.7	8.9	2.0	2.7	-0.7	0.3	1.2	1.5	1.5	3.0	2.6
Loneliness, isolation	1.5	2.1	6.8	1.9	2.6	0.7	1.3	1.6	0.6	0.6	1.7	0.2
Long-standing illness, disability or infirmity	1.1	1.7	4.1	-0.7	-0.2	-2.0	-1.3	-0.9	2.0	2.0	0.4	0.2
Ever had bowel cancer screening	1.7	2.0	4.1	1.2	1.6	-0.8	-1.1	1.2	1.8	1.8	2.0	0.8
Diabetes diagnosed by doctor	2.8	4.7	11.8	1.8	1.5	-2.3	-0.9	0.0	2.2	2.2	3.0	3.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.4	0.1	-0.8	0.9	0.4	-0.0	-1.2	-1.2	-1.0	-0.4
Friendships satisfaction	0.6	0.8	1.6	-1.1	-0.9	-0.9	-1.3	-1.2	0.6	0.6	-0.2	-0.4
Qualifications: nursing, teaching	0.2	0.4	1.1	-0.7	-0.9	-0.5	-0.1	-1.0	0.3	0.3	-0.6	0.3
Commuting to job workplace: Walk	0.7	0.7	2.7	1.2	1.0	-0.1	-0.1	0.8	0.1	0.1	0.9	1.6
Eye problems/disorders: Cataract	0.9	1.1	2.1	0.2	0.6	-1.4	-1.1	-0.5	1.4	1.4	0.9	1.0
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	4.2	-0.2	-0.7	-1.2	-0.7	-2.1	0.6	0.6	-0.3	1.6
Medication for cholesterol	0.4	0.6	2.7	-0.9	-0.4	0.3	-0.7	-0.9	0.0	0.0	-0.6	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.1	0.1	-0.1	-0.2	0.1	0.2	-0.2	0.3	0.3	-0.4	-0.1
Back pain experienced in last month	0.4	0.6	2.5	-0.5	-0.2	0.7	1.6	-0.3	-0.0	-0.0	-0.4	-1.3
Mineral and other dietary supplements	1.0	1.4	3.6	1.7	1.2	0.5	0.4	1.6	-0.3	-0.3	1.0	1.9
Breast cancer (self-reported)	0.2	0.2	0.6	-0.1	-0.1	0.6	-0.5	0.2	-0.8	-0.8	-0.3	-0.2
Asthma (self-reported)	0.9	1.9	4.0	-0.7	-0.1	-2.0	-1.1	-0.9	1.9	1.9	1.0	1.4
Osteoporosis (self-reported)	0.5	0.6	2.1	-1.0	-1.0	-0.3	-0.3	-1.4	0.4	0.4	-0.7	-0.6
Osteoarthritis (self-reported)	0.1	0.1	0.3	0.4	0.1	0.1	0.5	0.4	-0.1	-0.1	0.5	0.0
Medication: Aspirin	1.3	1.7	4.9	1.4	1.4	-0.2	0.5	2.1	0.9	0.9	2.2	0.3
Medication: Gliclazide	1.0	1.1	2.6	0.6	-0.2	-1.5	-1.1	-0.6	1.0	1.0	1.2	1.6
Illnesses of father: None of the above (group 1)	0.2	0.2	0.8	-0.6	0.1	0.7	-0.3	-0.0	-0.4	-0.4	-0.4	-0.9
Smoking status: Current	0.8	1.3	4.4	0.3	1.1	0.4	2.1	1.8	0.7	0.7	1.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	5.1	-2.3	-1.9	-0.4	-0.6	-2.1	0.2	0.2	-1.5	-2.2
Whole body water mass	0.2	1.3	3.0	-1.3	-1.7	0.1	-0.6	-1.3	-1.2	-1.2	-1.3	-0.2
Leg predicted mass (right)	0.1	0.7	2.0	-1.1	-1.4	-0.5	-1.0	-0.9	-0.6	-0.6	-0.8	0.1
Arm fat mass (left)	0.2	0.8	2.4	-0.8	-1.6	-0.0	-0.9	-0.9	-1.0	-1.0	-0.8	-0.2
Number of self-reported non-cancer illnesses	1.2	2.2	5.5	1.4	1.6	0.7	1.7	2.3	0.5	0.5	2.4	0.4
Average weekly champagne plus white wine intake	1.1	1.6	2.4	1.5	1.2	-0.9	-0.5	1.1	1.4	1.4	1.5	1.3
Miserableness	1.9	3.3	6.5	1.7	2.4	-1.1	1.3	0.7	1.6	1.6	2.6	2.4
Guilty feelings	0.1	0.1	0.5	0.6	0.7	0.1	0.1	0.4	-0.1	-0.1	0.4	0.3
Wears glasses or contact lenses	0.3	0.4	1.1	0.5	-0.1	0.6	-0.3	1.0	-0.9	-0.9	-0.2	-0.5
Ever taken oral contraceptive pill	3.6	4.0	11.2	1.1	1.0	2.8	3.4	2.4	-1.9	-1.9	-0.1	-1.4
Hearing aid user	0.4	0.5	1.9	1.4	0.1	-0.4	-0.4	1.1	-0.1	-0.1	0.1	1.0
Mother’s age at death	1.8	2.2	5.5	-1.0	-1.9	-2.2	-2.3	-2.0	0.7	0.7	-0.3	0.3
Financial situation satisfaction	1.5	1.8	3.7	1.2	1.3	-1.4	-0.8	0.2	1.9	1.9	1.3	1.3
Tinnitus: Yes, now most or all of the time	1.3	1.5	2.7	1.7	1.1	0.9	1.2	1.3	-1.2	-1.2	0.3	1.6
Commuting to job workplace: Public transport	0.1	0.2	0.4	-0.1	0.1	0.7	0.4	0.3	-0.3	-0.3	-0.6	-0.4
Eye problems/disorders: Glaucoma	0.3	0.3	0.6	-0.6	-0.7	-0.8	-0.0	-0.5	0.7	0.7	-0.4	0.0
Medication: Blood pressure	0.2	0.4	2.1	0.5	-0.2	-0.5	0.1	0.5	-0.3	-0.3	0.6	1.4
Pain type(s) experienced in last month: Hip pain	1.8	2.3	5.5	1.4	1.6	1.9	2.3	1.8	-0.9	-0.9	1.0	-1.0
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.6	-1.1	-1.0	0.2	-0.4	-0.6	-0.3	-0.3	-0.9	-1.9
High cholesterol (Self-reported)	0.5	1.0	1.8	1.2	0.8	0.9	1.3	1.3	-0.6	-0.6	1.2	0.7
Medication: Bendroflumethiazide	1.5	2.3	6.8	2.2	1.9	0.5	1.0	1.6	-0.2	-0.2	1.5	2.6
Medication: Paracetamol	1.9	3.0	6.8	1.7	2.3	-0.6	1.1	1.6	1.7	1.7	2.6	1.3
Medication: Lisinopril	0.1	0.2	0.9	0.1	0.1	-0.1	1.0	0.2	0.4	0.4	0.2	0.5
Medication: Atorvastatin	1.9	2.4	5.5	2.3	2.0	1.7	1.4	2.3	-0.7	-0.7	0.9	0.4
Illnesses of father: High blood pressure	1.0	1.2	3.7	0.3	0.1	-1.9	-0.3	-0.2	1.6	1.6	0.6	1.4
Alcohol drinker status: Never	0.3	0.4	1.3	1.1	0.2	-0.2	0.5	0.4	-0.3	-0.3	0.6	1.0
Ever smoked	0.7	1.2	3.8	-0.9	0.3	-0.8	0.2	-0.8	1.9	1.9	0.8	0.4
Basal metabolic rate	0.2	1.2	2.8	-1.2	-1.7	0.2	-0.6	-1.2	-1.3	-1.3	-1.3	-0.3
Leg fat percentage (left)	0.1	0.2	1.2	0.1	-0.7	0.0	-1.1	-0.4	-0.4	-0.4	-0.2	-0.1
Arm fat-free mass (left)	0.3	1.3	3.1	-1.3	-1.8	0.1	-0.7	-1.3	-1.2	-1.2	-1.3	-0.3
Number of operations (self-reported)	0.6	0.9	2.4	-0.4	0.0	-1.5	0.6	-0.4	1.5	1.5	0.7	0.4
Average weekly beer plus cider intake	0.3	0.4	1.3	-1.1	-0.5	-0.3	0.1	-1.1	-0.0	-0.0	-0.8	-0.2
Irritability	2.2	3.7	6.1	1.7	2.3	-1.5	-0.3	0.6	2.3	2.3	2.5	2.3
Risk taking	1.7	2.5	4.8	-2.2	-2.0	-1.2	-1.8	-2.1	0.9	0.9	-1.1	-1.4
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.8	0.6	0.3	1.4	0.2	0.6	-1.3	-1.3	-0.0	-0.0
Fractured/broken bones in last 5 years	0.2	0.2	0.5	-0.1	-0.7	-0.1	0.1	0.6	-0.7	-0.7	-0.4	-0.3
Age started oral contraceptive pill	0.8	1.0	2.9	-1.4	-1.7	-0.8	-0.8	-0.7	0.5	0.5	-1.0	-1.2
Diastolic blood pressure, automated reading	0.8	2.3	13.4	2.1	0.8	-1.0	0.4	0.7	-0.6	-0.6	0.7	3.7
Ever depressed for a whole week	0.1	0.2	0.5	0.7	0.2	-0.3	0.5	0.2	0.4	0.4	0.5	0.1
Unable to work because of sickness or disability	0.3	0.4	2.4	1.6	0.4	-0.3	-0.0	0.7	0.3	0.3	0.2	0.3
Commuting to job workplace: Cycle	0.1	0.2	0.6	0.0	0.8	0.3	0.6	0.5	0.1	0.1	-0.2	0.2
Myopia	0.5	0.8	3.1	0.7	0.5	-0.6	-0.8	0.1	0.4	0.4	1.3	1.7
Vascular/heart problems diagnosed by doctor	0.7	2.0	8.9	-1.8	-0.7	0.5	0.0	-1.4	0.4	0.4	-1.6	-3.0
Cholesterol lowering medication	0.6	0.9	1.6	0.8	0.1	-1.2	-0.9	0.7	1.1	1.1	0.9	1.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.8	0.6	0.5	0.5	0.7	0.8	0.2	0.2	0.7	-0.9
Pain experienced in last month	2.4	3.9	8.5	-2.6	-2.9	-0.8	-2.1	-2.7	-1.0	-1.0	-2.3	-0.4
Supplements: Calcium	0.4	0.4	1.4	-0.7	-0.6	-0.6	-1.2	-0.8	0.2	0.2	-0.2	-0.5
Basal cell carcinoma (self-reported)	1.2	1.4	3.4	-1.8	-1.6	-1.0	-0.3	-1.6	0.4	0.4	-1.1	-1.3
Heart attack/myocardial infarction (self-reported)	0.6	0.8	3.3	0.8	0.7	-0.0	-0.5	1.1	0.4	0.4	1.8	0.8
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	2.4	-1.0	-1.1	0.8	1.1	-0.9	-1.1	-1.1	-1.5	-0.7
Heart disease (siblings)	0.9	1.2	2.8	0.6	1.0	-0.8	-0.6	0.8	1.5	1.5	1.7	0.2
Alcohol drinker status: Previous	0.3	0.3	0.8	-0.4	-0.2	-0.9	-0.5	-0.3	0.8	0.8	0.1	-0.0
Pack years of smoking	1.3	2.0	4.7	-0.9	-0.6	2.1	1.1	0.2	-1.6	-1.6	-0.9	-2.2
Impedance of whole body	0.8	4.0	10.4	1.8	1.4	3.2	2.5	2.5	-1.6	-1.6	-0.5	-1.8
Leg fat mass (left)	0.1	0.5	1.5	-0.2	-1.1	-0.2	-1.2	-0.7	-0.6	-0.6	-0.5	-0.0
Arm predicted mass (left)	0.3	1.4	3.2	-1.3	-1.8	-0.1	-0.9	-1.6	-1.0	-1.0	-1.4	-0.3