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chr15:90,712,555-92,135,418

Best TWAS P=8.32e-19 · Best GWAS P=1.1e-15 conditioned to 0.671

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	FES	0.06	0.05	blup	46	0.07	7.4e-14	-8.0	8.9	8.3e-19	-0.88	0.00	1.00	TRUE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	FES	0.12	0.09	lasso	5	0.08	4.1e-09	-8.0	8.4	5.6e-17	-0.95	0.00	1.00	FALSE
3	GTEx	Cells Transformed fibroblasts	FES	0.28	0.17	enet	21	0.20	2.8e-15	-8.0	8.3	9.7e-17	-0.92	0.00	1.00	FALSE
4	GTEx	Lung	FES	0.24	0.07	lasso	6	0.05	5.1e-05	-7.7	8.3	1.2e-16	-0.90	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FES	0.08	0.07	enet	7	0.08	4.2e-09	-8.0	8.3	1.2e-16	-0.93	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	FES	0.30	0.30	lasso	7	0.32	1.3e-31	-7.8	8.3	1.4e-16	-0.95	0.00	1.00	FALSE
2	GTEx	Artery Tibial	FES	0.16	0.04	lasso	5	0.05	4.8e-05	-7.7	8.2	2.1e-16	-0.89	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	FES	0.05	0.04	lasso	2	0.04	2.2e-05	-8.0	8.2	2.6e-16	-0.95	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FES	0.13	0.16	lasso	2	0.14	6.1e-10	-8.0	8.0	1.2e-15	-0.99	0.00	1.00	FALSE
1	GTEx	Adipose Visceral Omentum	FES	0.21	0.09	lasso	5	0.05	1.3e-03	-8.0	8.0	1.4e-15	-0.99	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FES	0.06	0.02	blup	46	0.02	2.4e-02	-8.0	8.0	1.7e-15	-0.81	0.00	0.89	FALSE
21	The Cancer Genome Atlas	Stomach Adenocarcinoma	FES	0.04	0.01	blup	46	0.02	1.7e-02	-7.0	7.9	1.9e-15	-0.75	0.01	0.55	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FES	0.32	0.26	lasso	2	0.25	2.0e-09	-7.8	7.9	3.4e-15	-0.96	0.00	1.00	FALSE
6	GTEx	Thyroid	FES	0.33	0.19	lasso	6	0.18	4.3e-14	-7.7	7.9	3.9e-15	-0.95	0.00	1.00	FALSE
7	METSIM	Adipose	FES	0.08	0.06	lasso	3	0.05	6.8e-08	-7.4	7.6	3.1e-14	-0.88	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	FES	0.08	0.07	blup	46	0.06	3.4e-04	-6.3	7.4	1.1e-13	-0.84	0.04	0.87	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FES	0.06	0.03	blup	46	0.05	5.6e-06	-6.8	7.2	5.2e-13	-0.78	0.01	0.99	FALSE
5	GTEx	Skin Sun Exposed Lower leg	FES	0.09	0.04	lasso	5	0.04	1.4e-04	-8.0	7.2	7.4e-13	-0.91	0.00	0.99	FALSE
14	The Cancer Genome Atlas	Glioblastoma Multiforme	FES	0.12	0.06	enet	6	0.06	5.7e-03	-6.8	6.7	2.3e-11	-0.80	0.01	0.78	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FES	0.06	0.05	blup	46	0.06	1.9e-05	-7.0	6.6	3.0e-11	-0.74	0.02	0.96	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FES	0.10	0.07	enet	5	0.05	2.8e-06	-7.1	6.6	3.2e-11	-0.70	0.65	0.35	FALSE
8	YFS	Blood	FES	0.31	0.11	enet	77	0.22	1.2e-68	-8.0	6.3	2.6e-10	-0.61	0.00	1.00	FALSE
9	YFS	Blood	FURIN	0.11	0.03	enet	37	0.06	8.3e-19	4.3	5.3	1.2e-07	-0.48	0.98	0.02	FALSE