Best TWAS P=5.53e-14 · Best GWAS P=1.31e-13 conditioned to 0.179
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ARHGAP42 | 0.22 | 0.15 | enet | 18 | 0.19 | 1.7e-10 | 7.4 | 6.9 | 5.4e-12 | 0.85 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | TMEM133 | 0.30 | 0.15 | enet | 34 | 0.19 | 7.1e-11 | 7.1 | 6.3 | 3.2e-10 | 0.70 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | 7.1 | 7.4 | 1.2e-13 | 0.97 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | 7.1 | 7.5 | 5.5e-14 | 0.91 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ARHGAP42 | 0.04 | 0.01 | blup | 266 | 0.02 | 1.1e-04 | -4.1 | 5.4 | 5.3e-08 | 0.52 | 0.05 | 0.85 | FALSE |