Best TWAS P=9.8e-09 · Best GWAS P=1.76e-08 conditioned to 0.291
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DNAJC11 | 0.03 | 0.03 | lasso | 5 | 0.04 | 3.1e-05 | 5.6 | 5.7 | 1.3e-08 | 0.88 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | GPR153 | 0.13 | 0.03 | lasso | 5 | 0.01 | 1.3e-01 | 5.4 | -5.5 | 4.8e-08 | -0.94 | 0.02 | 0.80 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Female) | GPR153 | 0.07 | -0.01 | enet | 3 | 0.00 | 4.3e-01 | 5.4 | -5.2 | 1.6e-07 | -0.98 | 0.03 | 0.33 | FALSE |
| 4 | GTEx | Testis | THAP3 | 0.22 | 0.19 | lasso | 5 | 0.22 | 3.1e-10 | 5.4 | 5.7 | 9.9e-09 | 0.91 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DNAJC11 | 0.02 | 0.00 | blup | 74 | 0.01 | 9.1e-03 | 5.4 | 5.7 | 9.8e-09 | 0.90 | 0.02 | 0.70 | TRUE |