[Hub]/) : Traits : BMI :

chr9:130,175,096-132,180,229

Best TWAS P=9.49e-14 · Best GWAS P=6.02e-13 conditioned to 0.206

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum URM1 0.14 0.08 lasso 3 0.10 9.7e-06 4.0 -5.5 4.9e-08 -0.63 0.02 0.97 FALSE
2 GTEx Artery Coronary URM1 0.28 0.06 lasso 3 0.07 2.2e-03 3.9 -5.4 5.4e-08 -0.67 0.01 0.91 FALSE
3 GTEx Artery Coronary RP11-339B21.14 0.14 0.05 lasso 6 0.07 3.0e-03 6.7 -6.8 1.0e-11 -0.93 0.01 0.93 FALSE
4 GTEx Brain Caudate basal ganglia PKN3 0.26 0.00 lasso 10 0.04 2.4e-02 4.4 -5.4 8.2e-08 -0.41 0.06 0.16 FALSE
5 GTEx Brain Caudate basal ganglia RP11-339B21.15 0.30 0.02 lasso 6 0.01 1.7e-01 -3.0 -5.6 2.4e-08 -0.36 0.03 0.17 TRUE
6 GTEx Brain Cerebellar Hemisphere RP11-395P17.3 0.32 0.03 lasso 4 0.06 1.1e-02 4.1 5.5 4.2e-08 0.46 0.05 0.12 TRUE
7 GTEx Brain Cerebellum URM1 0.34 0.09 lasso 5 0.13 1.3e-04 3.9 -5.9 4.0e-09 -0.79 0.01 0.94 TRUE
8 GTEx Cells EBV-transformed lymphocytes URM1 0.35 0.19 lasso 6 0.22 8.0e-08 5.5 -6.0 2.4e-09 -0.62 0.07 0.84 FALSE
9 GTEx Cells Transformed fibroblasts URM1 0.23 0.07 lasso 4 0.10 2.8e-08 5.5 -5.3 1.1e-07 -0.63 0.16 0.84 FALSE
10 GTEx Cells Transformed fibroblasts RP11-339B21.14 0.19 0.12 lasso 8 0.12 6.3e-09 7.0 -6.9 4.1e-12 -0.88 0.00 1.00 FALSE
11 GTEx Esophagus Mucosa TRUB2 0.12 0.05 lasso 3 0.03 2.7e-03 5.9 -6.1 1.1e-09 -0.76 0.15 0.79 FALSE
12 GTEx Esophagus Mucosa URM1 0.12 0.04 lasso 2 0.05 2.8e-04 6.7 -6.3 2.2e-10 -0.87 0.01 0.98 FALSE
13 GTEx Esophagus Mucosa RP11-339B21.15 0.09 0.02 enet 4 0.02 2.9e-02 2.3 -5.2 2.3e-07 -0.55 0.02 0.83 FALSE
14 GTEx Esophagus Mucosa RP11-339B21.14 0.16 0.03 lasso 7 0.01 4.1e-02 7.0 -7.0 3.1e-12 -0.85 0.00 1.00 FALSE
15 GTEx Esophagus Muscularis URM1 0.20 0.09 lasso 7 0.10 2.2e-06 3.2 -5.7 9.6e-09 -0.60 0.07 0.92 FALSE
16 GTEx Heart Left Ventricle RP11-339B21.15 0.21 0.11 lasso 8 0.10 4.9e-06 5.9 -5.9 2.9e-09 -0.73 0.28 0.70 FALSE
17 GTEx Muscle Skeletal RP11-339B21.15 0.05 0.03 lasso 2 0.04 3.1e-05 5.9 -5.3 1.0e-07 -0.66 0.05 0.83 FALSE
18 GTEx Muscle Skeletal RP11-339B21.14 0.06 0.04 lasso 3 0.03 7.1e-04 5.5 -6.0 2.7e-09 -0.72 0.03 0.92 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic RP11-339B21.15 0.13 0.04 lasso 5 0.07 1.8e-04 7.0 -6.6 5.3e-11 -0.82 0.00 0.99 FALSE
20 GTEx Skin Sun Exposed Lower leg URM1 0.15 0.05 enet 9 0.11 1.7e-09 3.2 -6.0 2.3e-09 -0.71 0.00 1.00 FALSE
21 GTEx Spleen URM1 0.39 0.17 lasso 6 0.16 8.2e-05 3.2 -5.3 1.4e-07 -0.60 0.14 0.32 FALSE
22 GTEx Stomach RP11-339B21.14 0.11 0.04 lasso 6 0.05 1.7e-03 5.8 -6.2 4.3e-10 -0.73 0.01 0.91 FALSE
23 GTEx Testis SLC27A4 0.60 0.39 enet 27 0.45 4.1e-22 5.9 -5.7 1.6e-08 -0.74 0.55 0.45 FALSE
24 GTEx Thyroid CERCAM 0.37 0.05 lasso 9 0.08 9.0e-07 7.0 6.5 9.3e-11 0.71 0.00 1.00 FALSE
25 GTEx Thyroid RP11-339B21.13 0.11 0.00 enet 17 0.00 1.7e-01 4.1 7.5 9.5e-14 0.59 0.07 0.59 TRUE
26 GTEx Thyroid RP11-339B21.15 0.12 0.08 lasso 4 0.06 1.7e-05 5.9 -6.1 9.4e-10 -0.76 0.02 0.97 FALSE
27 METSIM Adipose CERCAM 0.02 0.00 blup 288 0.02 1.2e-03 4.1 6.0 2.0e-09 0.57 0.13 0.37 FALSE
28 METSIM Adipose RP11-339B21.14 0.05 0.05 enet 6 0.04 8.0e-07 6.7 -6.5 6.1e-11 -0.92 0.00 1.00 FALSE
29 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma URM1 0.08 0.05 blup 34 0.05 2.9e-06 4.1 -5.2 2.1e-07 -0.63 0.72 0.13 FALSE
30 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC27A4 0.02 0.02 lasso 2 0.02 5.2e-03 5.9 5.6 1.8e-08 0.71 0.02 0.61 FALSE
31 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma URM1 0.10 0.03 blup 31 0.04 1.3e-02 5.9 -5.5 4.0e-08 -0.67 0.00 0.72 FALSE