Best TWAS P=2.84e-10 · Best GWAS P=1.72e-11 conditioned to 9.95e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | MED27 | 0.12 | 0.05 | lasso | 5 | 0.04 | 1.1e-04 | 5.2 | 5.5 | 3.8e-08 | -0.08 | 0.02 | 0.98 | FALSE |
| 2 | YFS | Blood | MED27 | 0.05 | 0.06 | enet | 11 | 0.06 | 1.0e-19 | 5.7 | 5.6 | 2.2e-08 | -0.09 | 0.02 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FIBCD1 | 0.04 | 0.01 | blup | 87 | 0.02 | 5.2e-03 | 6.6 | 6.3 | 2.8e-10 | 0.72 | 0.01 | 0.83 | TRUE |