TWAS hub - PKN3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Caudate basal ganglia	0.2570	0.1030	5.1e-03	0.000	NA	0.033	NA	0.042	3.3e-01	NA	4.0e-02	NA	2.4e-02
2	GTEx	Colon Transverse	0.3700	0.0800	2.0e-08	0.349	NA	0.323	NA	0.341	2.2e-17	NA	5.5e-16	NA	6.2e-17
3	GTEx	Liver	0.6300	0.1130	2.4e-03	0.517	NA	0.407	NA	0.500	9.1e-17	NA	1.6e-12	NA	5.1e-16
4	GTEx	Small Intestine Terminal Ileum	0.2790	0.1080	3.5e-03	0.386	NA	0.278	NA	0.361	1.3e-09	NA	5.9e-07	NA	5.6e-09
5	GTEx	Stomach	0.2240	0.0830	8.5e-04	0.259	NA	0.196	NA	0.246	1.0e-12	NA	1.0e-09	NA	4.4e-12
6	METSIM	Adipose	0.0310	0.0167	6.0e-03	-0.001	0.005	-0.002	0.005	-0.002	5.4e-01	5.6e-02	8.9e-01	5.6e-02	9.8e-01
7	YFS	Blood	0.0728	0.0233	1.1e-11	0.048	0.045	0.052	0.050	0.052	2.5e-15	1.2e-14	1.9e-16	4.1e-16	1.3e-16
8	TCGA	Liver Hepatocellular Carcinoma	0.0740	0.0420	1.7e-03	0.030	0.045	0.046	NA	0.041	1.5e-02	3.6e-03	3.3e-03	NA	5.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Hypothyroidism (self reported)	10.5	24.2	33.2	-1.2	-5.8	-5.7	-5.7	-5.7	-2.5	-4.6	-5.7
Hypothyroidism/myxoedema (self-reported)	8.3	16.3	24.4	-0.0	-4.8	-4.8	-4.8	-4.8	-0.8	-3.6	-4.9
Blood White Count	7.0	51.5	77.1	-2.4	-8.7	-8.8	-8.8	-8.8	-3.2	-5.5	-7.6
Blood Platelet Count	6.0	69.4	110.2	-1.7	-10.4	-10.5	-10.5	-10.5	-0.9	-5.4	-9.1
Medication: Levothyroxine sodium	5.6	9.5	13.8	-1.0	-3.7	-3.7	-3.7	-3.7	-1.2	-2.5	-3.6
Falls in the last year	4.8	6.5	10.4	-1.5	-2.9	-2.9	-2.9	-2.9	-1.6	-2.0	-3.2
Vitamin and mineral supplements	4.2	5.7	8.1	-2.9	2.5	2.5	2.5	2.5	0.3	2.4	2.4
Tense / ‘highly strung’	3.9	6.4	9.6	-0.2	3.1	3.1	3.1	3.1	0.2	2.2	2.9
Medication: Seretide 50 evohaler	3.9	4.4	6.2	-1.8	-2.5	-2.5	-2.5	-2.5	-0.5	-1.3	-2.4
Heart disease (siblings)	3.9	4.7	9.5	-3.1	-2.2	-2.2	-2.2	-2.2	0.0	-2.4	-1.7
Allergy or Eczema	3.8	9.9	17.8	-3.3	-2.6	-2.5	-2.5	-2.5	-4.2	-3.6	-3.5
Illnesses of siblings	3.7	5.2	12.1	3.5	2.3	2.3	2.3	2.3	1.9	1.3	1.6
Ever depressed for a whole week	3.7	4.5	7.8	-1.9	-2.1	-2.1	-2.1	-2.1	-1.9	-2.8	-1.7
Illnesses of mother	3.6	4.5	7.6	2.3	2.2	2.2	2.2	2.2	2.8	0.8	1.6
Illnesses of father: Heart disease	3.6	5.0	6.9	-1.6	-2.6	-2.6	-2.6	-2.6	-2.1	-1.3	-1.9
Multivitamins +/- minerals	3.4	4.3	5.6	1.8	-2.3	-2.4	-2.4	-2.4	-0.8	-2.3	-1.8
Body Mass Index (BMI) (2010)	2.9	4.0	16.2	-3.1	-1.4	-1.4	0.0	0.0	-4.0	-1.4	0.0
Other serious medical condition/disability diagnosed by doctor	2.9	3.8	4.8	-0.8	-2.2	-2.2	-2.2	-2.2	-2.0	-1.9	-1.7
Respiratory disease	2.8	6.3	16.5	-2.6	-2.2	-2.1	-2.1	-2.1	-4.1	-2.2	-2.0
Average weekly fortified wine intake	2.7	3.2	9.4	1.8	-1.5	-1.6	-1.5	-1.5	-0.1	-3.1	-1.8
Wheeze or whistling in the chest in last year	2.7	4.9	6.0	-1.4	-2.4	-2.4	-2.4	-2.4	-2.4	-1.6	-2.3
Coronary Artery Disease (CAD)	2.6	3.1	11.8	-2.5	0.0	-2.5	0.0	0.0	-3.4	0.0	0.0
Loneliness, isolation	2.4	3.3	5.6	0.2	2.4	2.4	2.4	2.4	-0.0	1.0	1.8
Eye problems/disorders: Glaucoma	2.4	2.9	4.5	-1.3	2.1	2.1	2.1	2.1	-0.2	0.9	1.7
Hearing difficulty/problems with background noise	2.3	3.7	7.7	-2.8	-1.6	-1.6	-1.6	-1.6	-1.5	-2.5	-1.9
Ever taken oral contraceptive pill	2.3	2.6	4.9	-1.7	-1.7	-1.7	-1.7	-1.7	-1.2	-0.4	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.6	4.1	0.6	2.0	2.0	2.0	2.0	1.6	0.5	1.2
Commuting to job workplace: Walk	2.2	2.4	3.1	-1.2	-1.8	-1.8	-1.8	-1.8	-1.5	-1.1	-1.3
Glaucoma (self-reported)	2.1	2.5	3.8	-1.1	1.9	1.9	1.9	1.9	0.1	0.5	1.8
Heart disease (mother)	2.1	2.6	3.5	-1.7	-1.8	-1.9	-1.9	-1.9	-1.8	-0.5	-0.6
LDL Cholesterol	2.0	3.1	8.5	-0.3	-2.9	-2.9	0.0	0.0	-0.4	-2.8	0.0
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	5.6	-1.8	0.5	0.5	0.4	0.4	-2.3	-2.4	1.8
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	4.9	0.6	1.7	1.7	1.7	1.7	-1.3	2.2	1.5
Taking other prescription medications	1.9	2.9	6.5	0.5	-2.1	-2.0	-2.0	-2.0	0.2	-0.1	-2.6
Age at First Birth	1.8	2.6	3.9	1.2	1.9	1.9	1.9	1.9	0.6	0.9	2.0
Blood Red Count	1.8	17.4	26.4	-0.7	5.1	5.1	5.1	5.1	-0.9	3.7	4.3
Unable to work because of sickness or disability	1.8	2.3	4.0	-1.1	1.6	1.6	1.6	1.6	0.2	2.0	1.9
Had menopause	1.7	2.1	3.8	1.9	-1.4	-1.4	-1.4	-1.4	0.5	-1.1	-2.0
Gout (self-reported)	1.7	2.3	4.0	-2.0	-1.7	-1.7	-1.7	-1.7	-0.5	-1.3	-1.1
Emphysema/chronic bronchitis	1.7	1.9	2.9	-0.4	-1.6	-1.6	-1.6	-1.6	-0.4	-1.2	-1.7
Supplements: Vitamin C	1.7	2.0	14.6	3.8	0.3	0.3	0.3	0.3	1.1	0.1	0.2
Mineral and other dietary supplements	1.7	2.2	4.3	-1.7	1.6	1.6	1.6	1.6	-0.5	-0.0	2.1
Primary Biliary Cirrhosis	1.6	2.3	3.9	-0.4	-1.8	-1.8	-1.8	-1.8	-0.4	-0.9	-2.0
Waist Hip Ratio (WHR)	1.6	7.1	16.4	-0.4	2.9	2.8	2.8	2.8	0.5	3.0	4.0
Diabetes (mother)	1.6	2.0	12.5	-3.5	0.8	0.8	0.8	0.8	-0.6	0.1	0.9
Number of incorrect matches in round	1.6	2.7	3.7	0.5	-1.9	-1.9	-1.9	-1.9	-0.9	-1.6	-1.9
High blood pressure (siblings)	1.6	2.3	9.9	-3.1	-0.7	-0.7	-0.7	-0.7	-2.5	-0.3	0.0
Exposure to tobacco smoke outside home	1.5	2.0	3.2	0.3	-1.8	-1.8	-1.8	-1.8	0.3	-0.1	-1.7
Supplements: Fish oil (including cod liver oil)	1.5	1.9	3.6	1.9	-1.4	-1.3	-1.3	-1.3	1.2	0.1	-1.7
Pack years of smoking	1.5	2.2	4.1	-0.3	-1.6	-1.6	-1.5	-1.5	-0.1	-2.0	-1.9
Schizophrenia vs Biploar Disorder	1.4	1.9	6.1	-1.5	0.0	-2.4	0.0	0.0	-0.9	0.0	-2.5
Chronotype (morning person)	1.4	3.3	4.0	-1.1	-2.0	-2.0	-2.0	-2.0	1.8	-1.5	-2.0
Systolic blood pressure, automated reading	1.4	4.1	6.4	-0.7	-2.5	-2.5	-2.5	-2.5	-0.5	-1.5	-2.1
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	3.0	0.2	1.6	1.5	1.5	1.5	-1.0	0.2	1.7
Asthma	1.4	2.7	12.2	-2.0	-1.0	-1.0	-1.0	-1.0	-3.5	-1.1	-0.8
Lung cancer (father)	1.4	1.7	3.5	-1.5	1.2	1.2	1.2	1.2	0.5	1.9	1.1
Headache pain in last month	1.4	2.5	4.2	0.3	2.0	2.0	2.0	2.0	-0.2	1.6	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	2.6	-0.7	-1.6	-1.6	-1.6	-1.6	-1.0	-0.2	-1.4
Asthma (self-reported)	1.4	2.8	13.0	-2.0	-0.9	-0.9	-0.9	-0.9	-3.6	-1.3	-0.8
Crohns Disease (2012)	1.3	2.1	4.5	-1.1	2.1	2.1	0.0	0.0	-1.0	1.2	1.9
Schizophrenia (2014)	1.3	2.8	11.2	-1.7	0.0	-2.9	0.0	0.0	-0.4	0.0	-3.3
Blood Eosinophil Count	1.3	9.7	14.1	-1.5	-3.8	-3.7	-3.7	-3.7	-1.1	-2.5	-3.6
Diabetes (father)	1.3	1.6	3.6	-0.4	1.3	1.3	1.3	1.3	-0.9	1.0	1.9
Pack years adult smoking proportion	1.3	2.0	3.2	-0.1	-1.6	-1.6	-1.6	-1.6	0.3	-1.7	-1.8
Stomach or abdominal pain in last month	1.3	1.6	7.5	-2.7	-0.2	-0.2	-0.2	-0.2	-2.2	-0.7	0.0
Allergy	1.3	3.0	7.1	1.2	1.2	1.2	1.2	1.2	2.7	2.2	2.2
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.7	2.1	-1.1	-1.3	-1.3	-1.3	-1.3	-1.4	-1.2	-1.2
Number of full brothers	1.3	1.6	9.9	-3.1	0.6	0.6	0.6	0.6	-0.8	-0.0	1.0
Back pain experienced in last month	1.3	1.9	4.3	-0.7	1.4	1.4	1.4	1.4	1.0	2.1	1.2
Osteoporosis (self-reported)	1.3	1.6	3.9	1.4	0.9	0.8	0.9	0.9	2.0	1.8	0.6
Alzheimer’s Disease (in mother)	1.2	1.4	2.4	0.0	1.4	1.4	1.4	1.4	-0.5	0.2	1.5
Fasting Glucose	1.2	1.5	4.0	-0.1	1.4	1.4	1.4	1.4	-0.2	0.5	2.0
Supplements: Zinc	1.2	1.3	2.0	0.8	-1.4	-1.4	-1.4	-1.4	0.1	-0.8	-0.9
Chronic bronchitis/emphysema (father)	1.2	1.4	4.9	0.7	1.2	1.2	1.2	1.2	2.2	-0.1	0.4
Birth weight of first child	1.2	2.2	5.6	0.3	1.6	1.6	1.6	1.6	0.3	0.9	2.4
Comparative body size at age 10	1.2	3.4	8.8	-1.8	-1.6	-1.6	-1.6	-1.6	-3.0	-2.1	-0.8
Eye problems/disorders: None of the above	1.2	1.4	2.9	1.7	-1.3	-1.3	-1.3	-1.3	-0.2	-0.4	-1.2
Long-standing illness, disability or infirmity	1.2	1.8	8.1	-2.8	-0.7	-0.7	-0.7	-0.7	-1.4	-1.4	-0.9
Breast cancer (self-reported)	1.2	1.4	3.3	0.7	1.0	1.0	1.0	1.0	1.8	1.6	0.9
Schizophrenia (2018)	1.1	2.2	8.7	-1.5	0.0	-2.5	0.0	0.0	0.1	0.0	-3.0
Verbal and Numeric Reasoning (VNR)	1.1	2.5	5.1	0.7	1.5	1.5	1.5	1.5	2.3	1.1	2.0
Hand grip strength (left)	1.1	3.0	10.9	-3.3	-1.3	-1.3	-1.3	-1.3	-0.0	-1.9	-1.4
Hayfever, allergic rhinitis or eczema	1.1	2.4	6.1	-1.2	-0.9	-0.9	-0.9	-0.9	-2.4	-2.5	-1.7
Time employed in main current job	1.1	1.3	2.2	0.6	1.2	1.2	1.2	1.2	-1.5	1.1	0.9
Breastfed as a baby	1.1	1.4	2.8	1.7	1.1	1.2	1.2	1.2	1.5	-0.6	0.6
Pulse wave reflection index	1.1	1.4	1.8	1.3	-1.1	-1.0	-1.0	-1.0	1.3	-1.3	-1.4
Medication: Ibuprofen	1.1	1.3	1.6	-1.2	-1.3	-1.3	-1.3	-1.3	-1.1	-0.6	-0.9
Osteoarthritis (self-reported)	1.1	1.4	2.2	-1.3	1.1	1.1	1.1	1.1	-1.1	1.5	1.0
Pain type(s) experienced in last month: Hip pain	1.1	1.3	5.5	-2.3	0.6	0.5	0.5	0.5	-1.2	1.2	1.0
Commuting to job workplace: Cycle	1.1	1.3	2.1	1.4	1.1	1.1	1.2	1.2	1.1	-1.3	0.1
Crohns Disease (2017)	1.0	2.1	4.0	-0.8	1.6	1.6	1.6	1.6	-0.9	1.2	2.0
Triglycerides	1.0	1.6	4.2	-0.7	2.1	2.0	0.0	0.0	-1.5	1.2	0.0
BMI	1.0	5.6	28.7	-5.4	-0.0	-0.0	-0.0	-0.0	-3.8	-1.0	0.8
Systolic Blood Pressure	1.0	4.9	6.2	-2.4	-2.4	-2.5	-2.5	-2.5	-2.5	-1.1	-1.2
Hearing difficulty/problems: Yes	1.0	1.5	3.6	-1.1	-1.2	-1.2	-1.2	-1.2	-0.0	-1.9	-1.2
Age when periods started (menarche)	1.0	2.5	10.4	2.8	0.3	0.3	0.3	0.3	3.2	1.2	-0.2
Supplements: Glucosamine	1.0	1.3	2.0	0.3	-1.4	-1.4	-1.4	-1.4	-0.7	-0.6	-1.3
Medication for pain relief, constipation, heartburn	1.0	1.8	4.8	-0.1	1.2	1.2	1.2	1.2	2.2	0.8	1.6
Medication: Omeprazole	1.0	1.2	2.3	-1.5	-1.1	-1.1	-1.1	-1.1	-0.5	-0.6	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	5.4	-2.3	-0.8	-0.8	-0.8	-0.8	-0.9	-0.4	-0.7
Friendships satisfaction	1.0	1.3	2.3	0.4	-1.5	-1.5	-1.5	-1.5	0.0	-0.4	-0.8
Supplements: Calcium	1.0	1.1	2.6	0.9	1.0	1.0	1.0	1.0	1.6	1.3	0.2
Major Depression (MDD)	0.9	1.1	7.0	-2.6	0.0	-0.1	0.0	0.0	-1.2	0.0	0.1
HDL Cholesterol	0.9	1.4	4.5	0.3	-2.1	-2.1	0.0	0.0	0.5	-1.5	0.0
Number of treatments/medications taken	0.9	1.7	3.8	0.3	-1.5	-1.5	-1.5	-1.5	-0.5	-0.8	-1.9
Angina	0.9	1.2	2.0	0.2	-1.2	-1.2	-1.2	-1.2	-0.8	-1.2	-1.4
Medication: Metformin	0.9	1.3	2.2	1.1	1.2	1.2	1.3	1.3	1.5	0.4	0.6
Severe depression (siblings)	0.9	1.0	2.1	0.3	-0.9	-0.9	-0.9	-0.9	1.0	-1.3	-1.4
Maternal smoking around birth	0.9	1.3	1.9	0.2	-1.4	-1.4	-1.4	-1.4	0.1	-0.9	-1.3
Body mass index (BMI)	0.9	3.8	21.9	-4.7	-0.1	-0.1	-0.1	-0.1	-2.8	-0.8	0.1
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	3.9	-2.0	-0.5	-0.5	-0.5	-0.5	-1.9	-0.5	0.1
Migraine (self-reported)	0.9	1.2	3.0	-1.6	0.6	0.6	0.6	0.6	-1.5	1.7	0.6
Medication: Allopurinol	0.9	1.2	2.0	-1.1	-1.2	-1.2	-1.2	-1.2	0.4	-1.4	-0.6
Leg pain on walking	0.9	1.1	3.4	-1.8	-0.9	-0.9	-0.9	-0.9	-1.0	0.0	-1.1
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	1.8	-0.3	-1.3	-1.4	-1.3	-1.3	-0.6	0.0	-1.1
Mood swings	0.9	1.6	2.7	-1.6	1.3	1.3	1.3	1.3	0.0	1.5	1.2
Number of self-reported non-cancer illnesses	0.9	1.5	5.1	-1.1	-0.6	-0.6	-0.6	-0.6	-2.3	-1.9	-0.8
Basal cell carcinoma (self-reported)	0.9	1.1	2.5	1.6	1.1	1.0	1.0	1.0	-0.7	0.4	1.3
Depressed Affect (Nagel 2018)	0.8	1.6	4.0	-2.0	1.4	1.4	1.3	1.3	-0.4	0.0	1.2
Mean Putamen Volume	0.8	0.9	2.9	-0.2	1.4	1.4	0.0	0.0	-0.0	1.7	0.4
Rheumatoid Arthritis	0.8	1.1	4.0	-2.0	0.0	-0.8	0.0	0.0	-1.9	0.0	-0.8
Frequency of depressed mood in last 2 weeks	0.8	1.2	2.0	-0.9	1.2	1.2	1.2	1.2	-0.7	-0.3	1.4
Forced vital capacity (FVC)	0.8	3.0	5.7	-1.3	-1.9	-1.9	-1.9	-1.9	-0.8	-2.4	-1.3
Prospective memory result	0.8	1.0	2.5	1.4	-0.7	-0.7	-0.7	-0.7	1.0	-1.6	-0.8
Arm fat mass (right)	0.8	3.1	17.5	-4.2	0.3	0.3	0.3	0.3	-2.6	-0.3	0.6
Leg fat percentage (right)	0.8	2.7	18.8	-4.3	-0.1	-0.1	-0.1	-0.1	-1.8	0.1	0.3
Leg fat mass (right)	0.8	3.1	21.4	-4.6	-0.0	-0.0	-0.0	-0.0	-1.8	-0.2	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	1.3	0.8	-1.1	-1.1	-1.1	-1.1	1.1	-0.3	-0.4
Tinnitus: Yes, now most or all of the time	0.8	1.0	3.7	-1.9	-0.4	-0.4	-0.4	-0.4	-1.5	0.8	-0.7
Leg fat mass (left)	0.8	3.0	20.2	-4.5	-0.0	-0.0	-0.0	-0.0	-1.9	-0.2	0.2
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	3.1	0.0	-0.7	-0.7	-0.7	-0.7	0.1	-1.8	-0.9
Medication: Co-codamol	0.7	0.8	1.7	-1.3	0.8	0.8	0.8	0.8	-0.3	1.0	1.0
Relative age voice broke	0.7	1.1	4.2	2.0	-0.7	-0.7	-0.7	-0.7	1.4	-0.3	-1.1
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	3.3	-1.8	-0.1	-0.1	-0.1	-0.1	-1.8	-0.0	-0.0
High blood pressure (mother)	0.7	1.0	1.4	-1.2	-1.0	-1.0	-1.0	-1.0	-1.1	-0.5	-1.2
Had other major operations	0.7	0.9	5.5	-0.9	-0.3	-0.3	-0.3	-0.3	-2.3	0.4	0.4
Financial difficulties in last 2 years	0.7	1.0	4.3	-1.1	-0.7	-0.7	-0.7	-0.7	-2.1	-0.6	0.0
Arm fat percentage (right)	0.7	2.6	14.7	-3.8	0.0	0.0	0.0	0.0	-2.5	-0.2	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	7.0	-2.6	0.3	0.3	0.3	0.3	-0.9	0.4	1.0
Angina (self-reported)	0.7	0.9	1.3	0.1	-1.0	-1.0	-1.0	-1.0	-0.8	-1.2	-1.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	4.7	-2.2	-0.2	-0.2	-0.2	-0.2	-1.2	-0.0	0.1
Illnesses of siblings: Diabetes	0.7	0.9	1.9	-1.3	-0.8	-0.8	-0.8	-0.8	-1.4	-1.0	-0.1
Smoking status: Previous	0.7	1.0	1.6	-1.3	-0.9	-0.9	-0.9	-0.9	-0.1	-1.2	-1.3
Arm fat percentage (left)	0.7	2.6	14.3	-3.8	0.1	0.1	0.1	0.1	-2.5	0.0	0.7
Smoking status: Current	0.7	1.1	2.2	0.3	-1.2	-1.2	-1.2	-1.2	1.0	0.3	-1.5
Arm fat mass (left)	0.7	2.7	15.8	-4.0	0.4	0.4	0.4	0.4	-2.2	-0.1	0.7
Leg fat percentage (left)	0.7	2.7	17.4	-4.2	-0.2	-0.2	-0.2	-0.2	-2.0	-0.1	0.2
Myopia	0.7	1.0	1.8	0.8	-1.0	-1.0	-1.0	-1.0	1.1	-0.7	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	1.3	-1.2	-1.0	-1.0	-1.0	-1.0	-0.1	-0.8	-1.1
Bipolar Disorder or Schizophrenia	0.6	1.5	5.4	-1.5	0.0	-2.1	0.0	0.0	-0.2	0.0	-2.3
Sensitivity / hurt feelings	0.6	1.0	1.5	-0.6	-1.2	-1.2	-1.2	-1.2	0.4	-0.7	-1.2
Current tobacco smoking	0.6	1.0	1.7	0.1	-1.0	-1.0	-1.0	-1.0	1.1	0.6	-1.3
Waist circumference	0.6	2.0	12.5	-3.5	0.6	0.6	0.6	0.6	-1.4	0.3	0.7
Alcohol intake versus 10 years previously	0.6	1.0	5.2	-2.3	0.2	0.1	0.1	0.1	-1.5	-0.0	0.2
Father’s age at death	0.6	0.8	1.6	1.3	1.0	1.1	1.0	1.1	0.6	0.6	0.3
Noisy workplace	0.6	0.8	5.8	-2.4	0.2	0.2	0.2	0.2	-0.1	-0.0	0.3
Qualifications: A levels/AS levels or equivalent	0.6	1.2	3.0	-0.2	1.2	1.2	1.2	1.2	-0.6	0.6	1.7
Medication: Cholesterol lowering	0.6	0.9	2.0	-0.4	-1.0	-1.0	-1.0	-1.0	-1.4	0.1	-1.1
Blood clot in the leg (DVT)	0.6	0.7	4.3	-2.1	-0.2	-0.3	-0.2	-0.2	-0.9	-0.8	-0.2
Medication: Paracetamol	0.6	1.0	5.6	-1.3	-0.3	-0.3	-0.3	-0.3	-2.4	-0.2	-0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.4	-1.5	-0.6	-0.6	-0.6	-0.6	-1.5	-0.3	0.2
Mean time to correctly identify matches	0.6	1.2	6.3	1.5	-0.0	-0.0	-0.0	-0.0	2.5	-0.7	-0.9
Knee pain experienced in last month	0.6	0.9	4.5	-0.8	0.5	0.5	0.5	0.5	-0.4	2.1	0.8
Guilty feelings	0.6	0.9	3.5	-1.9	-0.4	-0.4	-0.4	-0.4	-1.4	-1.1	0.1
Number of operations (self-reported)	0.6	1.0	2.6	-1.1	-0.8	-0.9	-0.8	-0.8	-1.6	-1.0	-0.2
Risk taking	0.6	0.9	1.4	-1.2	1.0	1.0	1.0	1.0	-0.5	0.9	1.0
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	4.9	-2.2	-0.1	-0.1	-0.1	-0.1	-0.9	-0.6	0.0
Alzheimer’s Disease (including proxy)	0.5	0.7	1.9	1.4	0.8	0.8	0.8	0.8	0.3	0.3	0.9
Reaction Time	0.5	0.9	2.7	1.3	0.7	0.7	0.7	0.7	1.6	-0.9	-0.2
Ovarian Cancer	0.5	0.6	1.4	0.1	0.8	0.8	0.8	0.8	1.2	-0.5	0.8
HbA1C	0.5	0.5	2.2	-1.5	0.2	0.2	0.2	0.2	0.2	1.3	0.6
Smoking Status	0.5	1.2	3.2	-1.0	-1.1	-1.1	-1.1	-1.1	0.8	0.2	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.5	-1.2	0.8	0.8	0.8	0.8	0.5	-0.5	1.0
Qualifications: CSEs or equivalent	0.5	0.7	2.4	-1.6	0.2	0.2	0.2	0.2	-1.3	-0.7	0.9
Trunk fat mass	0.5	1.9	11.0	-3.3	0.5	0.5	0.5	0.5	-1.7	0.3	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.7	-1.9	0.7	0.6	0.6	0.6	-0.0	-0.0	1.2
Medication: Simvastatin	0.5	0.7	1.5	-0.4	-0.9	-0.9	-0.9	-0.9	-0.9	-0.4	-1.2
Weight	0.5	2.5	15.5	-3.9	0.2	0.2	0.2	0.2	-1.9	-0.5	0.3
Hip circumference	0.5	2.1	12.2	-3.5	-0.3	-0.3	-0.3	-0.3	-1.9	-0.8	-0.7
Hair/balding pattern: Pattern 3	0.5	0.8	1.1	-1.0	-1.0	-1.0	-1.0	-1.0	-1.1	-0.1	-0.6
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	3.6	-1.4	-1.4	-1.4	-1.4	-1.4	-0.3	-1.9	-0.9
Mouth/teeth dental problems: Dentures	0.5	0.8	2.7	-1.6	-0.8	-0.8	-0.8	-0.8	-0.7	-0.0	-1.1
Depression (self-reported)	0.5	0.6	2.0	-1.3	0.4	0.4	0.4	0.4	-1.4	0.6	0.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.5	-1.9	-0.5	-0.5	-0.5	-0.5	-0.7	0.4	-0.5
Loud music exposure frequency	0.5	0.6	1.5	-1.2	-0.5	-0.5	-0.5	-0.5	-1.0	-1.1	-0.3
Birth weight	0.5	1.0	4.6	-2.1	0.1	0.1	0.1	0.1	-1.2	0.8	1.1
Body fat percentage	0.5	2.1	12.5	-3.5	0.2	0.2	0.2	0.2	-1.9	0.6	0.6
Pulse wave peak to peak time	0.5	0.6	1.4	1.2	0.9	0.9	0.9	0.9	0.4	0.1	0.3
Shortness of breath walking on level ground	0.5	0.6	2.8	-0.8	-0.5	-0.5	-0.5	-0.5	-1.7	-0.2	-0.3
Whole body fat mass	0.5	2.2	13.2	-3.6	0.4	0.4	0.4	0.4	-1.8	0.2	0.7
Overall health rating	0.5	1.1	5.8	-2.4	0.4	0.3	0.3	0.3	-0.5	1.4	0.2
Chest pain or discomfort	0.5	0.7	2.3	-0.5	-0.7	-0.8	-0.8	-0.8	-1.5	-0.6	0.4
Eye problems/disorders: Cataract	0.5	0.6	3.5	-1.9	-0.3	-0.4	-0.3	-0.3	0.5	-0.5	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.4	-0.1	-0.8	-0.8	-0.8	-0.8	-1.5	-1.1	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	3.4	-0.2	-0.3	-0.3	-0.3	-0.3	-1.9	-0.9	-0.5
Medication: Bendroflumethiazide	0.5	0.7	1.1	0.6	1.0	1.0	1.0	1.0	0.1	1.1	0.5
Average weekly beer plus cider intake	0.5	0.7	2.6	-1.6	0.4	0.5	0.4	0.4	0.0	1.2	0.8
Ever had prostate specific antigen (PSA) test	0.5	0.5	2.2	0.4	-0.5	-0.5	-0.5	-0.5	-0.8	-1.5	-0.7
Heart attack/myocardial infarction (self-reported)	0.5	0.6	0.8	-0.0	-0.8	-0.8	-0.8	-0.8	-0.9	-0.8	-0.8
Ulcerative Colitis (UC)	0.4	0.7	1.1	-0.0	-1.0	-1.0	-1.0	-1.0	0.7	0.2	-0.9
Relative age of first facial hair	0.4	0.9	2.4	1.6	-0.6	-0.6	-0.6	-0.6	1.1	-1.2	-0.8
Impedance of leg (right)	0.4	1.8	4.5	2.0	0.6	0.6	0.6	0.6	2.1	1.9	0.9
Trunk fat percentage	0.4	1.7	9.3	-3.0	0.3	0.3	0.3	0.3	-1.7	0.6	0.9
Hand grip strength (right)	0.4	1.0	7.2	-2.7	-0.2	-0.2	-0.2	-0.2	0.1	-0.8	-0.1
Townsend deprivation index at recruitment	0.4	0.6	1.1	0.6	0.7	0.7	0.7	0.7	1.0	1.0	0.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.8	-0.3	-0.7	-0.7	-0.7	-0.7	-0.9	0.1	-0.6
High blood pressure	0.4	1.0	1.4	0.3	1.2	1.2	1.2	1.2	-0.7	0.5	1.2
Alcohol usually taken with meals	0.4	0.6	2.6	1.6	0.0	0.0	0.0	0.0	-0.8	-1.3	-0.0
Pain all over the body in last month	0.4	0.4	0.8	-0.1	-0.6	-0.6	-0.6	-0.6	0.9	-0.8	-0.5
Number of live births	0.4	0.5	2.9	0.3	0.4	0.4	0.4	0.4	0.7	-1.7	0.0
Pulse rate	0.4	0.6	2.8	-1.7	-0.4	-0.4	-0.4	-0.4	-1.1	0.3	-0.1
Pulse wave Arterial Stiffness index	0.4	0.5	1.5	-1.2	-0.7	-0.7	-0.7	-0.7	-0.2	0.1	-0.2
Worry too long after embarrassment	0.4	0.8	5.6	-2.4	-0.1	-0.1	-0.1	-0.1	-0.6	0.1	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	0.9	-0.3	0.9	0.9	0.9	0.9	0.2	0.4	0.6
Number of children fathered	0.4	0.4	1.9	-1.4	0.2	0.1	0.1	0.1	-0.3	0.6	1.0
Age at first live birth	0.4	0.8	1.1	0.4	-1.0	-1.0	-1.0	-1.0	-0.7	-0.6	-0.9
Alcohol intake frequency.	0.4	1.0	6.0	-2.4	-0.5	-0.5	-0.5	-0.5	-0.8	0.3	-0.8
Number of full sisters	0.4	0.5	1.0	0.1	-0.7	-0.7	-0.7	-0.7	0.5	-0.6	-1.0
Age at last live birth	0.4	0.6	1.4	0.1	-0.9	-0.8	-0.9	-0.9	-0.2	-1.2	-0.7
Medication: Aspirin	0.4	0.5	1.8	0.2	-0.4	-0.5	-0.4	-0.4	-1.4	-0.8	-0.7
Hypertension (Self-reported)	0.4	1.1	1.6	0.1	1.3	1.2	1.3	1.3	-0.8	0.5	1.3
Average weekly red wine intake	0.4	0.7	3.7	1.9	0.0	0.1	0.1	0.1	1.0	0.6	-0.2
Medication: Aspirin	0.4	0.5	1.8	-0.0	-0.6	-0.6	-0.6	-0.6	-1.4	-0.6	-0.9
Wears glasses or contact lenses	0.4	0.5	0.8	0.5	-0.7	-0.7	-0.7	-0.7	0.6	0.9	-0.6
Medication: Atorvastatin	0.4	0.5	0.8	-0.4	-0.9	-0.9	-0.9	-0.9	-0.2	0.7	-0.6
Fractured/broken bones in last 5 years	0.4	0.6	0.9	-0.5	-0.9	-0.9	-0.9	-0.9	-0.6	-0.6	-0.0
Impedance of whole body	0.4	1.8	8.0	2.8	0.3	0.3	0.3	0.3	1.7	1.8	0.5
Depression (Nagel 2018)	0.3	0.4	1.1	-0.8	0.6	0.6	0.6	0.6	-0.6	0.0	1.0
Lung FVC	0.3	1.4	2.4	-1.1	-1.2	-1.2	-1.2	-1.2	-0.3	-1.6	-1.2
Average weekly spirits intake	0.3	0.4	1.6	-0.5	-0.3	-0.3	-0.3	-0.3	-1.3	0.6	-0.4
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.1	-0.0	0.1	0.1	0.1	0.1	1.5	1.0	-0.6
Ever had hysterectomy (womb removed)	0.3	0.3	1.8	-1.3	0.2	0.2	0.2	0.2	0.1	0.3	0.6
Leg fat-free mass (left)	0.3	1.4	8.0	-2.8	0.1	0.1	0.1	0.1	-1.4	-1.0	0.1
Fed-up feelings	0.3	0.5	3.7	-1.9	0.1	0.1	0.2	0.2	-0.6	-0.3	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	0.8	-0.9	0.8	0.8	0.8	0.8	-0.9	0.6	0.6
Serious illness, injury or assault to yourself	0.3	0.4	1.9	-1.4	-0.2	-0.2	-0.2	-0.2	-0.2	-1.0	-0.3
Impedance of leg (left)	0.3	1.5	4.2	2.0	0.4	0.4	0.4	0.4	2.0	1.8	0.6
Leg predicted mass (left)	0.3	1.3	7.8	-2.8	0.1	0.1	0.1	0.1	-1.4	-1.0	0.2
Past tobacco smoking	0.3	0.6	1.3	1.1	0.7	0.7	0.6	0.6	-0.4	0.7	1.1
Heart attack	0.3	0.4	0.7	-0.1	-0.6	-0.6	-0.6	-0.6	-0.8	-0.9	-0.5
Diabetes (self-reported)	0.3	0.4	1.0	1.0	0.6	0.6	0.6	0.6	0.5	0.8	0.2
Fluid intelligence score	0.3	0.6	2.2	0.2	0.6	0.6	0.6	0.6	1.5	-0.2	0.9
Impedance of arm (right)	0.3	1.3	6.7	2.6	0.5	0.5	0.5	0.5	1.0	1.0	0.8
Worrier / anxious feelings	0.3	0.6	2.0	-0.8	-0.7	-0.7	-0.7	-0.7	-0.5	-1.4	-0.5
Impedance of arm (left)	0.3	1.4	7.3	2.7	0.3	0.3	0.3	0.3	1.0	1.4	0.7
Length of working week for main job	0.3	0.4	1.2	1.1	0.4	0.4	0.4	0.4	-0.7	-0.0	0.7
Peak expiratory flow (PEF)	0.3	0.8	3.8	-1.1	0.4	0.4	0.4	0.4	-1.9	-0.3	0.8
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	2.4	0.2	0.4	0.4	0.4	0.4	1.6	-0.2	0.6
Health satisfaction	0.3	0.3	1.8	-1.4	-0.4	-0.4	-0.4	-0.4	-0.6	0.1	0.2
Qualifications: College or University degree	0.3	0.8	2.4	1.6	0.7	0.7	0.6	0.6	-0.9	0.7	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.3	-0.9	0.0	0.0	0.0	0.0	-0.9	1.1	0.6
Leg fat-free mass (right)	0.3	1.3	7.3	-2.7	-0.1	-0.1	-0.1	-0.1	-1.5	-1.0	-0.1
Medication for cholesterol	0.3	0.5	1.6	0.3	-0.5	-0.5	-0.5	-0.5	0.1	-1.3	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	1.8	-1.3	-0.3	-0.3	-0.3	-0.3	-0.5	-1.3	-0.5
Average weekly champagne plus white wine intake	0.3	0.4	1.6	1.3	0.2	0.1	0.1	0.1	-1.3	-0.1	0.4
Commuting to job workplace: Public transport	0.3	0.4	2.2	1.5	0.0	0.0	0.0	0.0	-0.7	-0.3	-0.2
Alcohol drinker status: Never	0.3	0.4	0.6	0.2	-0.8	-0.8	-0.8	-0.8	-0.4	-0.2	-0.4
Ever smoked	0.3	0.5	2.0	-1.4	-0.5	-0.5	-0.5	-0.5	0.1	-0.2	-1.0
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.5	-0.2	-1.2	-1.2	-1.2	-1.2	0.4	-0.5	-1.0
Neuroticism (Nagel 2018)	0.2	0.5	2.5	-1.6	0.5	0.5	0.5	0.5	-0.6	0.0	0.6
Alzheimer’s Disease (in father)	0.2	0.3	1.1	1.0	-0.2	-0.3	-0.2	-0.2	0.7	0.4	-0.4
Breast Cancer	0.2	0.4	1.1	-1.0	-0.3	-0.3	-0.3	-0.3	-0.9	0.4	-0.7
Neuroticism (2016)	0.2	0.2	0.6	0.0	0.5	0.5	0.5	0.5	-0.3	-0.6	0.8
Type 2 Diabetes (T2D) (2012)	0.2	0.2	1.6	-0.5	0.0	-1.3	0.0	0.0	-0.4	0.0	0.0
Height	0.2	3.5	14.4	3.0	0.9	0.9	0.9	0.9	3.8	1.1	0.2
Cardiovascular Disease	0.2	0.5	2.4	-0.7	0.2	0.2	0.2	0.2	-1.6	-0.8	0.7
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.6	0.3	0.7	0.7	0.8	0.8	-0.2	0.2	0.4
Tanning	0.2	2.1	3.4	-0.5	-1.9	-1.9	-1.9	-1.9	0.8	-0.5	-1.6
Medication for hormone replacement therapy	0.2	0.3	0.6	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.8	0.1
Hair/balding pattern: Pattern 2	0.2	0.3	1.6	1.3	0.0	0.0	0.0	0.0	0.4	-0.7	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.5	-0.9	-0.4	-0.3	-0.4	-0.4	-1.2	-0.3	-0.4
Qualifications: None of the above	0.2	0.4	2.3	-1.5	-0.1	-0.1	-0.1	-0.1	-0.8	0.6	-0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.9	0.1	0.3	0.4	0.4	0.4	-0.2	-1.4	-0.1
Medication: Ramipril	0.2	0.2	1.6	1.3	-0.2	-0.2	-0.2	-0.2	-0.1	0.1	-0.1
Neuroticism score	0.2	0.5	1.0	-1.0	0.8	0.8	0.8	0.8	-0.1	-0.0	0.7
Medication: Lansoprazole	0.2	0.2	1.2	-1.1	-0.1	-0.1	-0.1	-0.1	0.1	0.5	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	2.0	-1.2	-0.3	-0.3	-0.3	-0.3	0.5	-1.4	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.7	-0.1	-0.7	-0.7	-0.7	-0.7	-0.2	-0.8	-0.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.9	0.0	-0.4	-0.5	-0.5	-0.5	-1.0	0.3	-0.3
Forced vital capacity (FVC), Best measure	0.2	0.6	3.0	-1.0	-0.5	-0.5	-0.5	-0.5	0.1	-1.7	-0.2
Arm fat-free mass (right)	0.2	0.8	5.6	-2.4	0.1	0.1	0.1	0.1	-0.8	-0.6	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.4	0.1	0.6	0.6	0.6	0.6	0.5	-0.1	-0.2
Neck or shoulder pain in last month	0.2	0.2	1.2	-1.1	0.2	0.2	0.2	0.2	-0.5	0.3	0.4
Medication: Blood pressure	0.2	0.3	2.2	-0.2	0.1	0.1	0.1	0.1	-1.5	-0.1	0.4
Arm predicted mass (right)	0.2	0.8	5.4	-2.3	0.0	0.1	0.1	0.1	-0.6	-0.7	-0.2
Pulse rate, automated reading	0.2	0.6	1.6	-1.0	0.4	0.4	0.4	0.4	1.1	1.2	-0.3
Had major operations	0.2	0.2	0.5	0.7	0.5	0.4	0.5	0.5	-0.4	-0.0	0.7
Family relationship satisfaction	0.2	0.2	0.3	-0.1	-0.5	-0.6	-0.6	-0.6	-0.6	-0.3	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.5	0.6	0.7	0.7	0.7	0.7	-0.0	0.5	0.6
Qualifications: nursing, teaching	0.2	0.4	2.0	-0.3	0.4	0.4	0.4	0.4	-1.4	0.1	0.4
Whole body water mass	0.2	0.9	5.1	-2.3	0.1	0.1	0.1	0.1	-0.9	-1.3	-0.2
Leg predicted mass (right)	0.2	1.2	6.7	-2.6	0.0	0.0	0.0	0.0	-1.4	-0.9	0.0
Hearing aid user	0.2	0.2	1.3	-1.1	0.1	0.1	0.1	0.1	0.0	-0.3	-0.5
Financial situation satisfaction	0.2	0.3	1.3	-0.5	0.3	0.3	0.3	0.3	-0.3	1.2	0.5
Medication: Blood pressure	0.2	0.3	0.5	0.6	0.5	0.5	0.5	0.5	-0.2	0.7	0.6
High cholesterol (Self-reported)	0.2	0.3	1.6	0.3	-0.4	-0.4	-0.4	-0.4	-1.3	-0.3	0.1
Medication: Paracetamol	0.2	0.3	1.2	-0.9	-0.2	-0.2	-0.2	-0.2	-1.1	-0.2	-0.2
Medication: Lisinopril	0.2	0.2	0.9	0.0	0.3	0.3	0.3	0.3	-0.1	-1.0	0.8
Illnesses of father: High blood pressure	0.2	0.3	1.0	-1.0	-0.3	-0.3	-0.3	-0.3	-0.6	-0.3	0.5
Basal metabolic rate	0.2	1.2	7.2	-2.7	0.1	0.2	0.2	0.2	-1.2	-1.0	-0.0
Arm fat-free mass (left)	0.2	1.1	7.2	-2.7	-0.0	0.0	0.0	0.0	-0.9	-1.0	-0.3
Pain experienced in last month	0.2	0.4	1.4	0.2	-0.5	-0.5	-0.5	-0.5	-0.9	-1.2	-0.1
Arm predicted mass (left)	0.2	1.1	7.1	-2.7	0.4	0.5	0.5	0.5	-0.7	-0.8	0.0
Bipolar Disorder (2018)	0.1	0.2	0.8	-0.5	-0.5	-0.5	0.0	0.0	-0.3	-0.9	-0.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	2.3	-0.1	-0.1	-0.1	-0.1	-0.1	1.5	0.0	-0.3
Worry (Nagel 2018)	0.1	0.2	0.7	0.8	0.5	0.6	0.5	0.5	0.1	0.0	0.2
Lupus	0.1	0.2	1.3	-1.2	0.2	0.2	0.2	0.2	0.1	0.4	0.2
Ulcerative Colitis	0.1	0.1	0.4	-0.1	0.0	-0.5	0.0	0.0	0.6	0.0	-0.2
Heel T-Score	0.1	0.8	3.2	-0.4	-0.4	-0.4	-0.4	-0.4	-1.8	-1.1	-1.1
Lung FEV1/FVC ratio	0.1	0.5	2.8	-1.7	-0.2	-0.2	-0.2	-0.2	1.2	0.1	-0.3
Hair Pigment	0.1	1.5	4.4	-1.3	-0.8	-0.8	-0.8	-0.8	-2.1	-1.6	-1.1
Sitting height	0.1	0.5	1.1	0.2	0.8	0.8	0.8	0.8	0.5	-0.0	1.1
Nervous feelings	0.1	0.2	1.1	-0.6	0.1	0.1	0.1	0.1	1.1	0.1	0.1
Mouth/teeth dental problems	0.1	0.2	1.1	0.0	-0.1	-0.1	-0.1	-0.1	1.1	0.1	0.4
Trunk fat-free mass	0.1	0.5	1.8	-1.4	0.2	0.2	0.2	0.2	-0.3	-1.2	-0.3
Happiness	0.1	0.1	0.3	0.1	-0.3	-0.3	-0.3	-0.3	-0.1	0.6	0.5
Trunk predicted mass	0.1	0.5	2.0	-1.4	0.2	0.3	0.3	0.3	-0.5	-1.2	-0.2
Standing height	0.1	0.8	2.2	1.2	0.7	0.7	0.7	0.7	1.5	0.6	0.5
Exposure to tobacco smoke at home	0.1	0.1	0.5	-0.2	-0.2	-0.2	-0.2	-0.2	-0.4	-0.1	-0.7
Hair/balding pattern: Pattern 4	0.1	0.3	1.7	0.5	0.1	0.2	0.2	0.2	-1.3	0.7	0.2
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.4	-0.3	0.3	0.3	0.3	0.3	0.6	0.2	0.4
Medication: Amlodipine	0.1	0.2	0.6	-0.5	0.4	0.3	0.3	0.3	-0.2	0.8	0.2
Suffer from ‘nerves’	0.1	0.2	1.1	1.1	-0.1	-0.0	-0.0	-0.0	-0.2	0.6	-0.5
Whole body fat-free mass	0.1	0.9	4.5	-2.1	0.0	0.1	0.1	0.1	-0.9	-1.2	-0.2
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.2	0.4	-0.4	-0.3	-0.4	-0.4	-0.4	-0.5	-0.5
Ever had bowel cancer screening	0.1	0.1	0.7	0.0	0.1	0.0	0.0	0.0	-0.8	0.3	-0.1
Diabetes diagnosed by doctor	0.1	0.2	0.2	-0.3	0.5	0.5	0.5	0.5	0.1	0.5	0.4
Medication: Gliclazide	0.1	0.1	0.2	0.4	0.5	0.5	0.4	0.4	-0.0	-0.0	0.5
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	-0.0	0.4	0.4	0.4	0.4	-0.3	0.2	0.3
Miserableness	0.1	0.2	0.8	-0.9	0.4	0.4	0.4	0.4	-0.1	-0.1	0.5
Mother’s age at death	0.1	0.2	0.6	-0.2	-0.1	-0.1	-0.1	-0.1	0.3	-0.7	-0.8
Irritability	0.1	0.1	0.5	-0.2	0.3	0.3	0.3	0.3	-0.7	0.1	0.3
Age started oral contraceptive pill	0.1	0.1	0.3	0.5	0.3	0.3	0.3	0.3	-0.4	-0.4	-0.5
Diastolic blood pressure, automated reading	0.1	0.4	0.7	-0.1	-0.8	-0.8	-0.8	-0.8	0.1	-0.1	-0.6
Alcohol drinker status: Previous	0.1	0.1	0.4	-0.3	-0.2	-0.2	-0.2	-0.2	0.5	-0.1	-0.6
Irritable Bowel Disease (IBD)	0.0	0.1	0.5	-0.4	0.0	0.0	-0.0	-0.0	-0.2	0.7	0.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Neuroticism	0.0	0.1	0.3	-0.5	0.3	0.2	0.2	0.2	0.1	-0.3	0.3
Medication: Atenolol	0.0	0.1	0.1	0.3	0.1	0.1	0.1	0.1	-0.3	-0.2	0.4
Comparative height size at age 10	0.0	0.1	0.3	-0.1	0.4	0.4	0.4	0.4	-0.6	0.3	0.4
Cholesterol lowering medication	0.0	0.1	0.1	-0.0	-0.3	-0.3	-0.3	-0.3	-0.1	0.2	-0.1

Hub : Genes

PKN3

Models

Trait associations