[Hub]/) : Traits : BMI :

chr13:27,300,215-29,372,443

Best TWAS P=5.79e-13 · Best GWAS P=1.78e-16 conditioned to 0.126

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FLT3 0.33 0.29 bslmm 556 0.32 3.6e-40 6.0 5.9 2.9e-09 -0.07 0.90 0.10 TRUE
2 CommonMind Brain Pre-frontal Cortex GTF3A 0.15 0.11 enet 26 0.13 4.1e-15 -5.2 6.6 3.3e-11 -0.74 0.08 0.92 TRUE
3 GTEx Adipose Subcutaneous MTIF3 0.29 0.16 lasso 4 0.19 2.4e-15 3.8 -5.9 2.9e-09 0.79 0.99 0.01 FALSE
4 GTEx Muscle Skeletal MTIF3 0.12 0.03 lasso 5 0.03 1.2e-03 -6.8 -6.8 8.7e-12 0.74 0.14 0.77 FALSE
5 GTEx Nerve Tibial AL137059.1 0.10 0.02 lasso 3 0.03 2.9e-03 4.3 -7.2 5.8e-13 0.71 0.02 0.94 TRUE
6 GTEx Testis MTIF3 0.45 0.28 lasso 11 0.25 1.8e-11 4.3 -5.3 1.4e-07 0.49 0.96 0.03 FALSE
7 YFS Blood GTF3A 0.17 0.15 lasso 5 0.19 1.1e-58 3.2 -5.5 4.9e-08 0.44 1.00 0.00 FALSE
8 YFS Blood MTIF3 0.07 0.05 enet 19 0.06 1.6e-18 -5.2 -6.6 3.1e-11 0.77 0.76 0.24 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma FLT3 0.05 0.04 lasso 6 0.03 1.5e-04 4.5 5.1 2.8e-07 0.05 0.17 0.05 TRUE
10 The Cancer Genome Atlas Brain Lower Grade Glioma GTF3A 0.03 0.00 enet 8 0.01 2.3e-02 1.1 6.7 1.7e-11 -0.63 0.01 0.85 FALSE