Best TWAS P=2.32e-08 · Best GWAS P=1.35e-07 conditioned to 0.326
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | TRIM47 | 0.30 | 0.17 | lasso | 2 | 0.17 | 1.1e-05 | 5.2 | -5.1 | 2.8e-07 | -0.97 | 0.01 | 0.97 | FALSE |
| 2 | GTEx | Brain Hypothalamus | TRIM65 | 0.26 | 0.09 | lasso | 7 | 0.12 | 9.7e-04 | 4.8 | 5.6 | 2.3e-08 | 0.85 | 0.02 | 0.71 | TRUE |
| 3 | GTEx | Breast Mammary Tissue (Female) | FBF1 | 0.14 | 0.13 | lasso | 3 | 0.13 | 1.2e-04 | 4.8 | 5.3 | 1.4e-07 | 0.82 | 0.04 | 0.67 | FALSE |
| 4 | GTEx | Lung | RP11-552F3.10 | 0.12 | 0.02 | lasso | 2 | 0.03 | 4.4e-03 | 5.3 | -5.5 | 3.8e-08 | -0.96 | 0.02 | 0.53 | FALSE |
| 5 | YFS | Blood | GALK1 | 0.05 | 0.04 | enet | 26 | 0.04 | 2.4e-13 | 5.2 | -5.4 | 8.5e-08 | -0.63 | 0.00 | 0.99 | FALSE |