[Hub]/) : Traits : BMI :

chr20:24,230,055-26,253,682

Best TWAS P=1.47e-19 · Best GWAS P=9.09e-13 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ABHD12 0.10 0.17 blup 405 0.17 1.7e-20 5.4 6.5 6.0e-11 0.67 0.99 0.01 FALSE
2 CommonMind Brain Pre-frontal Cortex ENTPD6 0.16 0.03 bslmm 446 0.05 1.1e-06 7.0 5.9 3.1e-09 0.68 0.00 0.99 FALSE
3 CommonMind Brain Pre-frontal Cortex NINL 0.19 0.17 lasso 20 0.23 1.2e-27 5.4 6.5 7.4e-11 0.57 0.99 0.01 FALSE
4 CommonMind Brain Pre-frontal Cortex PYGB 0.10 0.05 lasso 3 0.05 6.9e-07 5.1 -5.5 3.3e-08 -0.42 0.88 0.02 TRUE
5 GTEx Adipose Visceral Omentum ABHD12 0.06 0.00 lasso 8 0.00 4.6e-01 5.4 5.6 1.6e-08 0.63 0.23 0.08 FALSE
6 GTEx Artery Aorta NINL 0.17 0.18 lasso 6 0.19 1.5e-10 5.4 6.0 2.1e-09 0.64 0.98 0.02 FALSE
7 GTEx Artery Tibial ABHD12 0.12 0.12 enet 25 0.15 7.1e-12 5.3 5.7 1.1e-08 0.57 0.99 0.01 FALSE
8 GTEx Artery Tibial ENTPD6 0.24 0.12 lasso 9 0.17 2.1e-13 7.0 -5.2 1.8e-07 -0.83 0.01 0.99 FALSE
9 GTEx Brain Caudate basal ganglia ABHD12 0.09 0.05 enet 13 0.04 2.9e-02 5.4 5.6 2.8e-08 0.55 0.22 0.35 FALSE
10 GTEx Brain Cerebellar Hemisphere PYGB 0.20 0.16 lasso 5 0.12 5.8e-04 5.1 -5.2 2.0e-07 -0.67 0.10 0.69 FALSE
11 GTEx Brain Cerebellar Hemisphere ACSS1 0.31 0.24 lasso 3 0.16 7.1e-05 -5.9 -6.3 3.5e-10 -0.20 0.19 0.06 FALSE
12 GTEx Brain Cerebellar Hemisphere ENTPD6 0.22 0.26 lasso 3 0.17 3.8e-05 5.1 -5.4 5.3e-08 -0.60 0.54 0.40 FALSE
13 GTEx Brain Cerebellum ENTPD6 0.15 0.23 enet 8 0.14 4.6e-05 5.4 -5.5 3.3e-08 -0.61 0.52 0.36 FALSE
14 GTEx Breast Mammary Tissue CST7 0.10 0.00 lasso 4 0.00 7.3e-01 -5.6 5.5 3.1e-08 0.70 0.16 0.29 FALSE
15 GTEx Breast Mammary Tissue ABHD12 0.08 0.09 lasso 5 0.09 3.3e-05 5.4 5.6 2.6e-08 0.66 0.36 0.51 FALSE
16 GTEx Breast Mammary Tissue (Male) CST7 0.15 0.00 lasso 4 0.03 7.0e-02 -4.2 -5.5 3.7e-08 -0.18 0.06 0.08 FALSE
17 GTEx Breast Mammary Tissue (Male) ABHD12 0.06 0.01 lasso 3 0.02 1.3e-01 4.5 5.8 5.1e-09 0.80 0.03 0.52 FALSE
18 GTEx Cells EBV-transformed lymphocytes PYGB 0.38 0.08 lasso 5 0.06 7.0e-03 6.1 5.4 7.8e-08 0.65 0.39 0.11 FALSE
19 GTEx Cells Transformed fibroblasts ABHD12 0.24 0.33 lasso 4 0.35 6.3e-27 5.4 5.4 5.7e-08 0.56 0.99 0.01 FALSE
20 GTEx Esophagus Gastroesophageal Junction ABHD12 0.15 0.14 lasso 13 0.14 7.0e-06 5.0 5.2 2.1e-07 0.59 0.91 0.08 FALSE
21 GTEx Esophagus Mucosa NANP 0.07 0.00 lasso 7 0.01 5.1e-02 5.1 -5.7 1.4e-08 -0.61 0.13 0.24 FALSE
22 GTEx Esophagus Muscularis ABHD12 0.10 0.10 enet 42 0.09 4.5e-06 5.3 6.1 1.3e-09 0.60 0.79 0.21 FALSE
23 GTEx Esophagus Muscularis APMAP 0.09 0.06 enet 28 0.04 1.9e-03 4.7 5.3 1.2e-07 0.20 0.15 0.06 FALSE
24 GTEx Heart Atrial Appendage ABHD12 0.07 0.06 enet 16 0.06 1.0e-03 5.4 5.3 1.2e-07 0.57 0.50 0.39 FALSE
25 GTEx Heart Left Ventricle ABHD12 0.15 0.14 lasso 10 0.12 4.0e-07 5.5 6.1 1.2e-09 0.56 0.95 0.05 FALSE
26 GTEx Liver ABHD12 0.20 0.20 lasso 19 0.15 7.3e-05 5.5 5.3 1.0e-07 0.56 0.90 0.05 FALSE
27 GTEx Liver APMAP 0.20 -0.01 lasso 9 0.00 3.8e-01 5.4 5.5 3.7e-08 0.39 0.19 0.08 FALSE
28 GTEx Lung ABHD12 0.06 0.00 lasso 6 0.00 2.7e-01 7.0 7.1 1.2e-12 0.96 0.01 0.97 FALSE
29 GTEx Nerve Tibial PYGB 0.26 0.15 enet 11 0.14 5.7e-10 4.5 -5.5 3.4e-08 -0.60 0.96 0.04 FALSE
30 GTEx Nerve Tibial ABHD12 0.24 0.44 lasso 11 0.44 5.1e-34 5.5 -5.3 1.4e-07 -0.57 0.99 0.01 FALSE
31 GTEx Pancreas ENTPD6 0.11 0.05 enet 23 0.05 5.0e-03 7.0 -6.6 3.6e-11 -0.90 0.03 0.96 FALSE
32 GTEx Pituitary ABHD12 0.27 0.31 enet 25 0.31 1.8e-08 5.5 6.2 5.2e-10 0.63 0.88 0.12 FALSE
33 GTEx Skin Not Sun Exposed Suprapubic PYGB 0.12 0.13 enet 13 0.14 4.2e-08 4.8 -5.9 2.8e-09 -0.56 0.45 0.43 FALSE
34 GTEx Skin Sun Exposed Lower leg ABHD12 0.07 0.03 lasso 10 0.05 7.3e-05 5.4 6.3 3.5e-10 0.66 0.57 0.36 FALSE
35 GTEx Testis ABHD12 0.21 0.18 enet 25 0.23 1.1e-10 5.6 5.9 4.3e-09 0.63 0.98 0.02 FALSE
36 GTEx Thyroid ABHD12 0.05 0.04 lasso 5 0.03 3.9e-03 5.3 -5.4 8.2e-08 -0.57 0.76 0.02 FALSE
37 ROSMAP Brain Pre-frontal Cortex PYGB 0.20 0.10 bslmm 414 0.11 3.2e-14 5.6 -5.4 5.8e-08 -0.50 0.98 0.02 FALSE
38 ROSMAP Brain Pre-frontal Cortex ABHD12 0.26 0.35 enet 35 0.42 7.9e-58 5.4 6.7 2.9e-11 0.66 0.99 0.01 FALSE
39 ROSMAP Brain Pre-frontal Cortex APMAP 0.09 0.12 lasso 6 0.12 3.5e-15 -5.4 5.7 1.4e-08 0.19 0.99 0.01 FALSE
40 ROSMAP Brain Pre-frontal Cortex ENTPD6 0.32 0.10 bslmm 432 0.12 1.8e-15 7.0 9.0 1.5e-19 0.66 0.00 1.00 TRUE
41 YFS Blood ABHD12 0.15 0.35 bslmm 390 0.34 2.2e-118 5.6 5.9 4.4e-09 0.60 0.98 0.02 TRUE
42 YFS Blood NINL 0.04 0.03 lasso 8 0.03 2.8e-10 5.7 5.6 1.9e-08 0.51 0.97 0.03 TRUE
43 The Cancer Genome Atlas Bladder Urothelial Carcinoma ABHD12 0.04 0.00 blup 77 0.02 6.6e-03 5.4 5.2 1.5e-07 0.43 0.04 0.52 FALSE
44 The Cancer Genome Atlas Breast Invasive Carcinoma CST7 0.10 0.07 blup 60 0.07 7.3e-14 4.7 5.2 1.7e-07 0.02 0.24 0.75 TRUE
45 The Cancer Genome Atlas Breast Invasive Carcinoma PYGB 0.08 0.02 enet 7 0.03 1.7e-07 5.6 -5.5 3.6e-08 -0.59 0.92 0.06 FALSE
46 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PYGB 0.08 0.04 blup 74 0.06 1.0e-03 5.3 -6.1 9.9e-10 -0.75 0.09 0.65 TRUE
47 The Cancer Genome Atlas Colon Adenocarcinoma NINL 0.20 0.06 lasso 4 0.08 2.7e-05 4.8 5.6 2.8e-08 0.51 0.02 0.96 FALSE
48 The Cancer Genome Atlas Glioblastoma Multiforme ABHD12 0.14 0.10 lasso 5 0.13 1.1e-04 5.3 5.4 5.5e-08 0.52 0.06 0.89 FALSE
49 The Cancer Genome Atlas Glioblastoma Multiforme VSX1 0.12 0.08 blup 46 0.05 1.2e-02 -5.5 6.5 5.9e-11 0.24 0.04 0.32 FALSE
50 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ABHD12 0.04 0.03 blup 77 0.04 4.0e-05 5.7 5.5 4.5e-08 0.49 0.05 0.94 FALSE
51 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ABHD12 0.03 0.01 blup 77 0.01 8.7e-03 4.0 5.6 2.4e-08 0.67 0.06 0.75 FALSE
52 The Cancer Genome Atlas Brain Lower Grade Glioma ABHD12 0.04 0.06 blup 77 0.06 2.2e-07 5.5 5.7 1.3e-08 0.57 0.08 0.92 FALSE
53 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ABHD12 0.07 0.05 blup 77 0.05 2.4e-03 5.3 5.1 2.8e-07 0.58 0.06 0.81 FALSE
54 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ABHD12 0.08 0.09 blup 80 0.09 1.7e-06 5.5 5.2 1.8e-07 0.58 0.07 0.93 FALSE
55 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ENTPD6 0.07 0.07 lasso 1 0.04 9.2e-03 5.1 -5.1 3.0e-07 -0.60 0.08 0.08 FALSE
56 The Cancer Genome Atlas Prostate Adenocarcinoma PYGB 0.21 0.13 enet 5 0.17 2.0e-17 4.0 -5.3 1.5e-07 -0.65 1.00 0.00 FALSE
57 The Cancer Genome Atlas Thyroid Carcinoma ENTPD6 0.16 0.14 lasso 4 0.13 1.2e-12 5.1 -5.2 2.0e-07 -0.60 1.00 0.00 FALSE
58 The Cancer Genome Atlas Thyroid Carcinoma NINL 0.08 0.14 lasso 11 0.13 2.9e-12 5.6 -5.3 9.0e-08 -0.57 0.03 0.97 FALSE
59 The Cancer Genome Atlas Thyroid Carcinoma PYGB 0.10 0.08 lasso 7 0.07 1.4e-07 4.6 -5.8 6.4e-09 -0.76 0.06 0.94 FALSE