Hub : Genes

APMAP

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.2256	0.0930	1.0e-03	0.010	NA	0.020	NA	0.025	1.4e-01	NA	6.4e-02	NA	4.4e-02
2	GTEx	Colon Transverse	0.1560	0.0520	3.3e-05	0.089	NA	0.123	NA	0.103	5.2e-05	NA	1.8e-06	NA	1.4e-05
3	GTEx	Esophagus Mucosa	0.1270	0.0580	2.8e-03	0.001	NA	0.038	NA	0.012	2.6e-01	NA	1.3e-03	NA	5.0e-02
4	GTEx	Esophagus Muscularis	0.0880	0.0420	6.1e-03	0.057	NA	0.040	NA	0.022	2.3e-04	NA	1.9e-03	NA	1.6e-02
5	GTEx	Liver	0.1980	0.0840	1.1e-03	-0.009	NA	-0.004	NA	-0.002	7.3e-01	NA	4.4e-01	NA	3.7e-01
6	GTEx	Testis	0.2360	0.0680	3.2e-05	0.063	NA	0.102	NA	0.103	9.5e-04	NA	2.9e-05	NA	2.5e-05
7	GTEx	Whole Blood	0.3320	0.0740	8.2e-09	0.056	NA	0.079	NA	0.098	7.4e-06	NA	1.0e-07	NA	2.7e-09
8	ROSMAP	Brain Pre-frontal Cortex	0.0907	0.0249	2.4e-11	0.119	0.075	0.110	0.086	0.120	5.2e-15	6.7e-10	5.7e-14	3.3e-11	3.5e-15

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.5	0.9	2.1	1.4	0.8	0.6	0.9	0.6	-0.9	0.3	1.3
Bipolar Disorder or Schizophrenia	0.0	0.1	0.3	0.2	0.5	-0.4	0.1	0.3	-0.5	0.1	0.3
Depressed Affect (Nagel 2018)	0.5	1.1	5.1	1.2	1.2	0.2	0.5	2.2	0.1	0.4	-0.8
Depression (Nagel 2018)	0.6	0.9	3.6	0.9	0.6	0.3	1.0	1.9	-0.5	-0.9	-0.4
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.6	1.1	-0.6	-0.4	0.5	0.7	-0.6	0.5	1.6
Neuroticism (Nagel 2018)	0.4	0.8	2.4	0.8	1.4	0.7	0.4	1.5	0.1	0.3	-1.0
Schizophrenia (2018)	0.2	0.3	0.9	-0.9	-0.0	-1.0	-0.6	-0.1	0.0	-0.1	-0.7
Schizophrenia vs Biploar Disorder	1.1	1.5	3.7	-1.8	-0.4	-1.9	-1.0	-0.0	0.1	-0.4	-1.9
Worry (Nagel 2018)	0.4	0.8	4.0	-0.6	1.0	0.2	-1.1	0.3	-0.1	0.4	-2.0
Alzheimer’s Disease (in mother)	0.6	0.7	2.2	1.3	0.1	-0.4	1.5	0.4	-0.2	0.2	1.1
Alzheimer’s Disease (in father)	0.2	0.2	0.8	-0.2	-0.9	0.1	-0.4	-0.6	-0.2	0.4	0.6
Alzheimer’s Disease (including proxy)	0.1	0.2	0.4	0.6	-0.6	-0.2	0.4	-0.4	0.3	0.4	0.3
Crohns Disease (2017)	1.0	2.2	7.2	2.0	1.7	0.2	0.3	2.7	-1.7	-0.1	0.8
Irritable Bowel Disease (IBD)	0.0	0.1	0.5	-0.3	-0.1	0.0	0.0	-0.2	0.4	0.2	0.7
Ulcerative Colitis (UC)	1.1	2.1	5.2	-2.0	-1.7	-0.3	-0.1	-2.3	2.0	0.7	0.7
Major Depression (MDD)	0.3	0.4	1.0	0.6	-0.6	-0.7	-0.6	0.9	-0.1	1.0	0.1
Reaction Time	0.4	0.8	1.8	0.4	0.9	-1.0	1.3	1.0	-0.1	-1.1	0.7
Verbal and Numeric Reasoning (VNR)	2.5	5.9	11.9	3.4	1.3	-0.8	1.9	3.3	-2.6	0.2	3.4
Breast Cancer	1.4	3.3	10.6	1.5	2.0	0.3	3.2	0.6	0.5	-1.9	2.3
Ovarian Cancer	0.2	0.3	1.1	-0.5	0.6	0.4	-0.1	1.0	0.3	-0.3	0.0
Prostate Cancer	1.6	2.3	7.1	0.3	0.3	0.4	-1.7	-0.8	-2.2	-1.8	-2.7
Age at First Birth	1.5	2.2	6.5	0.2	0.6	1.4	-2.6	-1.7	-1.9	0.8	-1.3
Bipolar Disorder (2011)	0.4	0.4	1.1	0.8	0.3	-0.9	1.0	-0.5	-0.1	-0.2	0.2
Body Mass Index (BMI) (2010)	1.9	2.6	6.5	2.3	1.2	-0.4	1.4	2.1	-1.1	-0.3	2.6
Coronary Artery Disease (CAD)	0.2	0.2	1.0	-0.3	0.1	-1.0	-0.4	-0.0	0.1	0.6	0.1
Crohns Disease (2012)	1.3	2.0	5.7	1.8	1.6	0.1	-1.3	2.4	-1.7	0.6	-0.1
Mean Putamen Volume	1.3	1.5	4.2	-1.4	-1.1	0.4	-1.7	-2.0	-0.2	0.0	-1.2
Fasting Glucose	0.7	0.8	2.4	0.4	-1.5	0.6	-0.6	-1.5	-0.4	0.4	1.0
HbA1C	0.4	0.4	2.7	-0.1	0.5	-0.1	0.6	0.5	-0.2	-1.6	-0.1
HDL Cholesterol	0.2	0.4	0.9	0.4	-0.4	0.6	0.7	-1.0	0.3	0.3	0.7
LDL Cholesterol	1.2	1.9	5.8	-1.0	1.1	-2.4	0.5	1.6	1.9	-0.9	-0.6
Lupus	0.4	0.6	1.9	0.1	-0.8	0.0	-1.4	0.6	-0.5	1.1	-0.1
Neuroticism (2016)	0.2	0.3	0.7	0.6	-0.7	-0.8	-0.5	-0.5	-0.1	0.3	-0.3
Primary Biliary Cirrhosis	0.3	0.5	2.4	-0.1	0.0	-1.6	-0.8	0.6	-0.4	-0.2	-0.6
Rheumatoid Arthritis	0.5	0.7	3.0	0.5	0.6	-0.9	-0.5	1.7	-0.9	0.6	-0.2
Schizophrenia (2014)	0.3	0.6	1.8	-0.9	0.9	-1.3	0.0	0.2	-0.3	-0.7	-1.0
Triglycerides	0.1	0.2	0.4	-0.2	-0.4	0.5	0.1	0.6	0.1	-0.5	-0.0
Type 2 Diabetes (T2D) (2012)	0.9	1.0	4.8	0.6	0.3	1.3	-0.6	0.5	-2.2	-0.3	0.9
Ulcerative Colitis	0.9	1.4	3.5	-1.9	-1.2	0.6	-1.2	-1.7	0.9	0.1	-0.7
Blood Eosinophil Count	0.0	0.3	1.4	0.3	1.2	0.1	0.3	0.7	0.4	-0.4	0.4
Blood Platelet Count	0.8	9.1	28.4	-1.3	4.1	0.6	4.4	0.3	2.4	-5.3	0.0
Blood Red Count	0.5	4.9	24.4	-4.9	-2.1	-1.9	-1.2	-2.0	0.6	0.3	-1.0
Blood White Count	0.3	2.5	6.0	1.2	0.2	1.1	2.4	2.2	1.9	0.4	1.7
Heel T-Score	0.1	1.1	4.6	-0.0	-0.9	-0.5	-2.1	-1.2	0.4	0.6	-1.0
BMI	2.8	16.5	32.1	4.8	2.7	0.4	5.3	5.5	-2.5	-2.0	5.7
Height	0.2	3.7	16.3	0.7	1.1	-3.4	-0.2	4.0	-0.4	0.1	0.1
Waist Hip Ratio (WHR)	0.6	2.5	4.9	1.8	1.2	1.2	1.8	2.2	-0.6	0.5	2.1
Systolic Blood Pressure	0.7	3.4	11.4	-2.3	-3.4	-0.7	-0.3	-2.0	1.6	1.7	0.5
Smoking Status	2.4	5.8	15.1	3.9	1.8	1.0	3.0	3.2	-0.7	-1.5	2.3
Allergy or Eczema	0.6	1.6	3.7	-1.0	0.3	1.7	0.3	-1.7	0.4	-1.9	-1.4
Cardiovascular Disease	0.6	2.0	7.0	1.8	-0.6	2.6	0.2	1.9	-1.3	0.5	0.6
Hypothyroidism (self reported)	0.3	0.6	1.8	0.6	-0.1	-0.3	-0.0	1.3	-1.3	-0.0	0.9
Respiratory disease	1.0	2.2	8.2	2.9	0.1	0.4	1.7	1.9	-0.8	-0.6	1.3
Type 2 Diabetes (T2D) (2018)	0.6	1.1	2.4	0.5	-0.9	1.3	1.5	-0.3	0.5	1.2	1.5
Lung FEV1/FVC ratio	0.7	3.8	12.9	-3.6	-2.8	-0.9	-1.0	-2.5	1.1	0.7	-0.0
Lung FVC	1.0	5.1	23.8	-2.9	-1.1	1.3	-1.4	-4.9	-0.6	-0.3	-1.6
Neuroticism	0.6	1.5	6.1	1.2	1.0	0.4	-0.3	2.5	0.1	1.3	-1.2
Chronotype (morning person)	0.3	0.8	2.0	-1.1	1.0	-0.9	-0.5	-0.3	-0.7	-0.6	-1.4
Hair Pigment	0.1	4.3	13.7	-2.3	1.5	0.1	1.9	-2.4	0.5	-3.7	-1.8
Tanning	0.4	4.7	13.4	3.7	-0.6	0.9	2.0	2.3	-0.2	1.1	3.5
Hand grip strength (left)	0.7	1.8	6.6	1.1	-0.0	-2.1	-0.4	1.4	-2.6	-0.1	-0.2
Number of treatments/medications taken	0.7	1.2	3.1	-1.3	-1.8	0.3	-0.2	-0.9	1.4	1.0	1.2
Average weekly spirits intake	0.2	0.3	0.9	0.4	1.0	0.0	-0.1	0.8	-0.7	0.5	-0.1
Sensitivity / hurt feelings	0.2	0.3	1.0	0.4	0.0	0.5	0.7	1.0	0.1	-0.4	0.6
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.5	1.2	-0.8	-0.3	0.8	1.2	-0.3	0.2	0.4
Hearing difficulty/problems: Yes	1.2	1.8	10.0	0.7	0.7	3.2	0.6	-0.9	0.1	-1.5	0.5
Relative age of first facial hair	0.3	0.6	1.8	-0.2	0.7	-0.1	-0.5	0.7	-0.9	-1.1	-1.3
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	4.1	-1.4	-1.3	0.7	-1.9	-1.4	0.8	2.0	0.7
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.3	0.3	0.8	-0.6	1.4	1.5	0.7	0.3	0.3
Ever had hysterectomy (womb removed)	0.9	1.1	2.7	-0.9	-0.6	-1.4	-0.8	1.0	0.7	0.6	-1.6
Systolic blood pressure, automated reading	0.3	1.0	2.3	-1.5	-0.9	-1.3	0.9	0.4	0.9	0.4	1.0
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	3.1	-0.0	1.8	0.1	1.1	1.5	-0.3	-1.7	-0.9
Angina	0.6	0.7	2.4	-0.4	-1.0	-1.2	-0.4	1.5	0.6	0.3	0.4
Medication for hormone replacement therapy	0.3	0.4	0.7	-0.2	-0.7	0.1	0.6	-0.7	0.5	-0.7	0.8
Vitamin and mineral supplements	1.0	1.3	6.1	0.9	2.5	-0.0	0.5	1.6	-0.7	0.6	-0.0
Supplements: Zinc	0.6	0.6	2.6	-0.0	-1.6	0.2	0.0	-0.5	1.3	0.6	0.2
Medication: Co-codamol	1.1	1.3	4.0	-0.4	-2.0	1.0	0.4	-1.1	1.3	1.1	1.1
Medication: Metformin	0.3	0.4	1.2	0.2	-0.1	0.6	1.1	0.8	-0.6	-0.3	0.7
Diabetes (father)	0.4	0.5	1.5	-0.1	-0.2	1.2	0.3	-1.2	-0.8	0.3	-0.4
Diabetes (mother)	0.8	1.0	3.9	0.3	-1.1	-2.0	-0.1	-0.3	0.1	0.7	1.5
Severe depression (siblings)	2.0	2.2	5.9	1.9	0.6	1.5	1.5	1.6	-1.1	0.1	2.4
Pack years adult smoking proportion	1.1	1.7	4.8	2.2	0.5	-0.1	1.5	2.1	-0.5	-0.2	1.4
Impedance of leg (right)	0.6	2.9	8.0	-1.4	-1.5	-1.7	-2.8	-1.0	1.5	1.1	-1.9
Leg fat-free mass (left)	1.6	8.2	24.4	3.5	1.6	0.2	3.0	4.9	-2.8	-0.8	3.0
Trunk fat percentage	2.3	9.1	31.4	3.2	1.4	-0.9	3.1	5.6	-0.4	-0.0	4.3
Hand grip strength (right)	0.5	1.4	5.1	1.0	-0.1	-1.3	-0.5	1.9	-2.3	0.2	0.1
Townsend deprivation index at recruitment	0.5	0.8	2.8	0.6	-0.7	-0.1	0.9	0.2	1.7	0.5	1.2
Current tobacco smoking	1.6	2.6	9.6	1.8	1.0	0.4	3.1	1.6	0.2	-0.9	1.9
Average weekly fortified wine intake	0.5	0.6	1.4	-0.3	0.4	-0.2	-1.2	0.5	-1.1	-0.8	-1.2
Maternal smoking around birth	1.9	2.8	8.7	2.0	-0.0	0.9	1.7	1.8	0.3	1.5	2.9
Fed-up feelings	0.5	0.8	3.6	0.4	1.2	1.9	0.7	0.4	0.6	-0.3	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	7.8	1.7	0.6	0.6	1.1	2.8	-0.8	-1.3	-0.1
Relative age voice broke	0.6	0.9	3.6	0.1	0.7	0.9	-0.5	0.4	-0.8	-1.9	-1.1
Taking other prescription medications	1.0	1.6	5.7	-0.6	-1.2	0.5	-2.0	0.8	-0.3	2.4	0.1
Age when periods started (menarche)	0.5	1.1	2.8	-1.3	0.3	-0.4	-1.2	-0.6	-0.9	-1.2	-1.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.7	-0.6	-0.6	-0.6	-0.3	-0.2	0.8	0.3	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	7.3	2.1	0.5	2.7	0.4	-0.3	-1.4	-0.6	1.8
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.4	-0.2	-1.0	-0.1	0.0	0.0	1.3	1.5	1.1
Qualifications: CSEs or equivalent	0.3	0.4	1.4	-0.5	-1.0	-1.2	0.7	0.4	-0.1	-0.3	-0.1
Serious illness, injury or assault to yourself	0.3	0.4	1.7	-0.1	-0.6	0.8	0.7	1.3	0.2	0.1	-0.1
High blood pressure	0.3	0.9	2.5	0.3	-1.4	1.6	0.1	0.8	0.1	1.2	0.5
Hayfever, allergic rhinitis or eczema	0.5	1.1	2.0	-1.4	-0.3	0.8	-0.9	-1.4	0.7	-0.6	-1.4
Multivitamins +/- minerals	1.1	1.4	6.5	-0.6	-2.5	-0.2	-0.5	-1.7	1.1	-0.4	0.2
Stomach or abdominal pain in last month	0.3	0.4	1.1	-1.0	-0.4	-0.8	0.1	-0.5	0.4	0.7	-0.7
Supplements: Glucosamine	0.5	0.7	1.9	-0.2	1.2	0.0	1.3	-0.2	-0.1	-1.4	-0.8
Diverticular disease/diverticulitis (self-reported)	1.6	1.8	5.4	1.7	-0.1	2.3	-0.3	1.5	-0.6	0.7	1.8
Medication: Atenolol	0.2	0.2	0.9	-0.2	-0.2	-0.3	-0.9	0.5	-0.3	0.4	-0.3
Medication: Levothyroxine sodium	0.9	1.5	6.7	0.6	-0.8	-0.3	-1.7	1.1	-2.6	0.6	-0.0
Sitting height	0.9	6.1	27.1	1.9	2.0	-3.0	0.8	5.2	-1.9	-0.9	0.0
Chronic bronchitis/emphysema (father)	1.2	1.5	3.1	1.3	1.8	1.4	1.6	1.3	0.4	-0.3	0.8
High blood pressure (mother)	0.2	0.3	0.9	-0.1	-0.9	0.5	0.5	0.6	-0.5	0.7	0.0
Body mass index (BMI)	2.6	11.0	27.9	3.9	1.7	0.9	4.3	4.5	-1.3	-0.8	5.3
Impedance of leg (left)	0.7	3.4	7.0	-1.7	-1.7	-2.0	-2.6	-1.4	1.9	0.8	-2.1
Leg predicted mass (left)	1.6	8.4	24.8	3.5	1.6	0.1	3.0	5.0	-2.8	-0.8	3.1
Trunk fat mass	2.6	11.2	39.1	3.7	1.6	-1.0	3.4	6.3	-1.2	-0.2	4.5
Waist circumference	2.8	10.1	25.5	3.7	2.1	0.4	4.0	5.0	-1.8	-1.2	4.1
Number of incorrect matches in round	0.5	0.8	3.5	0.1	0.5	1.9	-0.6	1.0	-0.6	0.3	-0.8
Past tobacco smoking	0.2	0.3	1.0	-0.8	1.0	-0.6	-0.1	-0.3	-0.4	0.2	-0.3
Alcohol usually taken with meals	1.1	1.8	9.6	-0.2	0.3	0.4	-3.1	0.2	-0.8	0.8	-1.8
Nervous feelings	0.3	0.5	1.8	-0.8	0.4	-0.1	-1.0	-0.8	-0.4	0.1	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	6.3	1.3	0.7	0.8	0.6	2.5	-0.7	0.3	-0.0
Hearing difficulty/problems with background noise	0.7	1.1	3.3	-0.0	-0.3	1.8	0.1	-1.7	1.1	-1.0	0.5
Hair/balding pattern: Pattern 2	0.9	1.1	2.7	0.9	1.2	1.0	0.8	-0.7	-0.0	-1.6	1.3
Had menopause	0.3	0.4	1.1	-1.0	-0.0	-0.5	0.8	0.5	-0.1	-0.3	0.7
Had other major operations	1.1	1.3	2.8	0.9	0.6	1.1	-1.7	0.2	-1.6	1.7	0.0
Forced vital capacity (FVC)	0.9	3.4	7.6	-2.0	-2.0	-0.5	-2.3	-2.8	-1.2	0.3	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	3.2	1.1	-0.2	1.8	-0.1	-0.5	-1.0	-0.6	1.3
Ever unenthusiastic/disinterested for a whole week	2.5	3.1	11.7	3.4	-0.7	0.9	1.3	1.1	-1.5	1.2	2.2
Qualifications: None of the above	0.7	1.4	3.8	-0.8	-0.6	-1.1	1.1	-0.5	2.0	1.4	1.4
Financial difficulties in last 2 years	1.0	1.3	3.3	1.8	-1.3	0.6	1.2	0.8	-0.2	-0.4	1.6
Mouth/teeth dental problems	0.2	0.3	0.8	-0.0	-0.5	0.1	-0.9	-0.0	-0.8	0.5	-0.6
Heart attack	1.7	2.2	6.8	-1.7	-0.2	-1.6	-1.5	1.7	-0.5	0.2	-2.6
Allergy	0.2	0.5	1.5	0.5	0.0	-0.5	0.3	0.1	-0.6	1.1	1.2
Pain all over the body in last month	1.4	1.5	4.2	0.7	1.7	2.0	0.2	1.0	-1.1	-1.4	0.1
Diabetes (self-reported)	0.7	1.1	2.7	0.0	-1.6	0.9	1.6	-0.4	0.6	0.9	1.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.1	-0.8	-0.8	1.0	-0.3	-0.2	0.3	-0.1	-0.4
Medication: Ramipril	1.4	1.8	3.7	-1.6	-1.4	-1.3	-1.9	0.6	0.6	1.2	-1.5
Medication: Simvastatin	0.6	0.8	1.7	-1.2	-0.9	-1.3	0.5	-0.2	1.1	-1.1	0.4
Fluid intelligence score	1.4	2.9	8.3	2.1	1.1	-0.3	1.9	2.0	-0.9	-0.4	2.9
Illnesses of siblings	0.3	0.4	1.1	0.8	0.3	-0.5	-0.4	-1.1	-0.4	-0.2	-0.7
Neuroticism score	0.4	0.8	2.1	0.9	0.7	0.7	-0.7	1.3	0.0	0.6	-1.4
Weight	2.1	10.4	32.4	3.7	1.8	-0.4	3.5	5.7	-1.9	-0.8	4.2
Impedance of arm (right)	0.5	2.3	4.4	-1.6	-0.4	-1.4	-2.1	-1.3	1.8	0.2	-2.1
Arm fat percentage (right)	2.1	8.4	20.4	3.5	1.6	0.2	3.3	4.5	-0.5	-0.4	4.5
Trunk fat-free mass	0.7	3.8	12.9	2.1	0.7	-0.6	1.7	3.6	-2.3	-0.3	2.0
Hip circumference	1.6	6.7	17.3	3.5	1.4	-0.1	2.6	4.2	-1.8	-1.1	3.3
Time employed in main current job	0.6	0.6	3.5	-0.4	0.1	-1.9	-0.7	0.5	-0.2	-0.9	-0.0
Alcohol intake versus 10 years previously	1.1	1.6	6.5	-2.5	-0.3	-0.9	0.1	-1.6	1.4	-0.6	-0.5
Father’s age at death	0.7	1.0	2.5	-0.3	-0.8	-0.8	-1.6	-0.7	-1.0	1.5	-0.7
Worrier / anxious feelings	0.9	1.7	4.4	0.7	1.0	0.7	-1.8	1.3	-1.0	1.2	-2.1
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	3.4	0.8	1.0	0.7	1.6	1.3	-1.8	-1.4	-0.3
Falls in the last year	1.0	1.3	5.3	-0.7	-0.8	1.0	-1.6	-2.3	0.4	0.5	-0.3
Hair/balding pattern: Pattern 3	0.3	0.5	1.4	-0.4	-0.3	-1.1	-0.3	0.2	-0.1	1.2	-0.7
Number of live births	1.0	1.4	4.2	1.3	2.0	-0.5	0.6	2.0	-0.4	-0.4	0.3
Forced expiratory volume in 1-second (FEV1)	1.3	4.5	11.4	-2.2	-3.1	-0.2	-2.3	-3.4	-0.8	0.9	-1.7
Pulse rate	0.6	1.0	2.7	-1.7	-0.7	-1.0	-0.9	0.8	0.7	-0.1	-1.2
Happiness	0.6	0.8	3.4	-0.3	0.7	-0.5	1.8	-0.6	0.6	-1.1	0.3
Noisy workplace	0.9	1.1	5.2	0.7	-0.4	-0.7	0.4	-0.0	-2.3	0.8	1.2
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.1	0.7	0.6	0.4	-0.9	0.2	-1.5	-0.7	-0.1
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	2.9	-0.5	-1.7	0.3	-0.8	-1.0	1.6	1.3	0.8
Mouth/teeth dental problems: Dentures	0.6	1.0	3.1	-0.2	-0.5	-0.8	0.9	1.8	1.6	1.0	0.4
Asthma	0.5	1.0	4.8	1.8	0.1	-0.2	0.1	2.2	-0.3	-0.1	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.6	0.8	-0.7	0.8	0.1	-0.3	-0.3	0.1	0.8
Medication: Cholesterol lowering	0.2	0.3	0.9	-0.6	-0.9	-0.7	0.2	0.5	0.6	0.0	0.4
Depression (self-reported)	1.6	2.0	4.7	2.1	-0.4	1.8	-0.2	2.2	-1.1	1.3	0.0
Medication: Lansoprazole	0.8	0.9	1.7	0.6	-1.1	0.6	1.0	-0.9	0.7	-1.0	1.3
Prospective memory result	0.4	0.5	1.6	-0.4	0.2	-1.2	-0.4	-0.7	-0.8	-0.3	-0.7
Lung cancer (father)	0.6	0.7	1.3	1.1	0.4	1.1	-0.1	0.7	-1.1	0.6	0.9
Illnesses of mother	0.4	0.5	1.6	0.1	0.2	1.3	0.0	-1.1	0.9	0.6	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.1	12.3	-2.1	-2.3	0.1	-2.3	-3.5	-1.1	0.8	-2.0
Pulse wave Arterial Stiffness index	0.8	0.9	4.1	0.4	-0.6	0.0	-0.8	0.8	0.7	2.0	1.1
Impedance of arm (left)	0.8	3.5	8.7	-2.1	-0.5	-1.7	-2.9	-1.2	1.4	0.4	-3.0
Arm fat mass (right)	2.6	10.6	29.6	4.0	1.7	0.0	3.6	5.4	-1.3	-0.5	4.7
Trunk predicted mass	0.7	3.8	13.0	2.1	0.7	-0.7	1.7	3.6	-2.2	-0.4	2.0
Standing height	0.3	3.2	10.3	-0.2	0.5	-3.0	-1.2	3.2	-1.4	-0.1	-1.7
Length of working week for main job	0.7	0.8	2.6	1.6	0.6	-0.3	0.6	1.5	-0.4	-0.1	0.7
Exposure to tobacco smoke at home	0.5	0.5	1.2	1.1	-0.5	0.4	0.1	1.0	0.3	0.7	1.1
Breastfed as a baby	1.1	1.4	4.6	0.1	0.2	2.1	-0.6	-2.2	-0.0	-1.3	-0.1
Tense / ‘highly strung’	0.4	0.7	1.8	-0.2	1.0	0.3	-0.2	0.2	-0.8	-1.3	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	2.9	1.4	-0.5	1.7	-1.2	1.4	-1.6	0.3	-1.4
Hair/balding pattern: Pattern 4	0.2	0.4	1.6	1.3	-0.3	0.6	0.0	0.7	-0.1	0.8	0.5
Birth weight of first child	0.3	0.6	1.4	0.5	0.6	-0.3	0.4	1.2	0.4	1.0	1.1
Peak expiratory flow (PEF)	0.8	2.0	5.9	-0.6	-2.4	-0.4	-1.9	-0.9	-1.2	1.6	-1.0
Pulse wave reflection index	0.9	1.2	4.7	0.8	-0.7	0.8	-0.2	-0.9	0.5	2.2	1.3
Ever highly irritable/argumentative for 2 days	0.6	0.8	3.3	0.6	1.8	0.6	0.2	1.2	-0.6	-0.5	0.1
Loud music exposure frequency	0.5	0.6	2.3	-0.1	-0.6	-0.2	0.9	-0.7	-0.6	-0.4	1.5
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.8	-0.6	-0.7	0.3	-1.7	-0.4	-1.4	-0.5	-1.4
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	3.3	1.5	0.9	0.9	1.5	-0.0	0.1	-0.9	1.8
Blood clot in the leg (DVT)	0.1	0.1	0.4	-0.3	-0.4	-0.1	-0.3	0.6	0.3	-0.0	0.3
Medication: Paracetamol	0.6	1.0	2.6	-1.6	-1.1	-1.0	0.6	-1.4	1.0	0.5	-0.1
Headache pain in last month	1.3	2.3	7.4	-1.5	-1.4	-1.4	-1.6	-0.6	0.9	0.9	-2.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	2.4	1.0	1.6	-0.4	0.6	0.2	-0.9	-1.4	-0.5
Glaucoma (self-reported)	0.9	1.1	2.9	-0.0	-0.8	1.7	-0.6	-1.5	0.7	0.5	1.2
Gout (self-reported)	1.0	1.3	2.8	-0.1	-1.2	-0.4	1.0	-1.0	1.7	1.5	1.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.6	-0.1	-1.1	-1.2	-0.7	0.7	-0.9	0.7	0.4
Medication: Amlodipine	1.5	2.1	5.1	1.2	0.5	1.6	2.2	1.5	-1.2	-1.1	1.6
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.9	1.6	0.7	-0.4	0.5	2.0	-1.2	-0.7	-0.4
Birth weight	1.0	2.1	8.6	-1.8	-1.1	-2.9	0.6	-0.3	1.7	0.3	-0.1
Chronic bronchitis/emphysema (mother)	2.7	3.1	7.5	1.8	2.7	1.2	-0.0	1.9	-2.3	-2.0	-0.4
High blood pressure (siblings)	0.2	0.3	0.6	-0.6	-0.3	0.8	0.3	0.5	0.6	0.1	0.7
Forced vital capacity (FVC), Best measure	0.8	2.9	8.8	-1.9	-1.1	-0.3	-1.8	-3.0	-1.2	0.2	-2.2
Body fat percentage	2.5	9.8	31.1	3.5	1.6	-0.7	3.3	5.6	-0.5	-0.2	4.5
Leg fat percentage (right)	2.8	10.2	29.7	4.0	1.3	-0.2	3.2	5.5	-0.4	0.0	4.9
Arm fat-free mass (right)	1.1	5.6	19.7	2.5	0.8	-0.6	2.2	4.4	-2.7	-0.2	2.2
Exposure to tobacco smoke outside home	0.7	1.0	3.5	0.7	-0.8	0.1	1.0	0.3	0.8	1.1	1.9
Comparative body size at age 10	0.6	1.7	7.2	1.8	0.9	-1.1	0.4	2.7	-0.4	0.9	0.1
Number of full brothers	0.4	0.5	3.0	-0.4	0.1	-1.0	0.1	0.5	-0.0	-1.7	-0.2
Worry too long after embarrassment	0.8	1.3	2.5	1.4	1.0	0.9	-1.2	1.6	-0.8	0.8	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.7	-0.7	-0.2	1.0	-0.6	-0.3	-0.1	0.3	-1.3
Wheeze or whistling in the chest in last year	1.1	2.0	6.3	2.5	-0.1	0.4	0.6	2.5	-0.0	0.8	1.4
Number of children fathered	0.8	0.9	1.9	-0.8	-0.0	-1.3	-0.9	1.2	0.2	-0.8	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	3.4	-1.1	-0.8	-1.5	-1.6	0.1	0.2	0.2	-1.8
Age at first live birth	0.6	1.0	4.3	-0.4	-0.4	0.7	-1.4	-0.4	-2.1	1.0	-0.2
Pulse wave peak to peak time	0.8	0.9	4.1	-0.3	0.7	-0.1	0.7	-0.5	-0.8	-2.0	-1.1
Health satisfaction	0.8	1.0	2.8	1.6	-0.5	0.9	-0.4	1.7	-1.2	0.2	0.8
Shortness of breath walking on level ground	0.3	0.4	1.6	0.1	0.8	0.2	0.6	0.1	-0.4	-1.3	0.0
Qualifications: College or University degree	0.9	2.8	7.1	0.4	0.9	2.1	-2.7	-0.4	-2.7	0.5	-1.7
Eye problems/disorders: None of the above	0.8	0.9	2.2	-0.2	-1.5	-0.8	-0.5	-1.3	0.7	1.3	0.3
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.5	0.4	1.0	0.6	1.6	0.6	-0.1	-1.0	0.6
Emphysema/chronic bronchitis	0.5	0.5	2.0	1.0	0.8	0.2	0.3	1.4	-0.3	0.4	-0.4
Medication for pain relief, constipation, heartburn	0.1	0.2	0.7	0.4	0.7	0.2	-0.8	0.4	0.2	0.5	-0.1
Neck or shoulder pain in last month	2.1	3.0	6.3	-2.5	-2.2	-0.6	-1.8	-1.7	2.3	1.3	-0.3
Medication: Blood pressure	0.7	1.2	3.8	-1.2	-2.0	0.5	-0.6	-0.3	1.1	1.4	0.4
Angina (self-reported)	0.6	0.8	2.7	-0.3	-1.0	-1.2	0.0	1.6	0.7	0.2	0.7
Migraine (self-reported)	0.4	0.4	1.2	-0.2	0.7	0.7	-0.7	0.7	-1.1	-0.4	-0.5
Medication: Ibuprofen	0.4	0.5	1.7	1.3	-0.3	1.0	0.4	0.1	-0.7	-0.1	0.7
Medication: Allopurinol	0.6	0.8	2.8	0.2	0.2	0.7	1.6	-0.3	0.8	0.1	1.7
Medication: Omeprazole	1.0	1.2	2.6	0.6	1.1	1.3	1.5	0.9	-0.4	-0.3	1.6
Medication: Seretide 50 evohaler	1.1	1.3	6.0	-0.4	-1.5	-0.0	-0.8	0.3	1.1	2.5	0.4
Mean time to correctly identify matches	0.4	0.8	2.0	0.2	0.5	-1.1	1.4	0.8	0.5	-0.3	1.4
Heart disease (mother)	0.4	0.5	1.6	-0.6	-0.8	-0.3	-0.0	0.1	1.0	1.2	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.1	0.0	0.6	0.5	-1.0	-0.1	-0.6	1.4	-0.2
Whole body fat mass	2.8	11.8	37.8	4.0	1.8	-0.5	3.5	6.1	-1.5	-0.4	4.7
Leg fat mass (right)	3.2	12.5	37.0	4.5	1.8	0.1	3.7	6.1	-1.7	-0.5	4.8
Arm predicted mass (right)	1.2	6.0	22.3	2.8	0.8	-0.5	2.1	4.7	-2.7	0.0	2.4
Pulse rate, automated reading	0.2	0.7	2.0	-1.3	-1.1	0.0	0.6	1.4	0.3	0.4	-0.1
Alcohol intake frequency.	1.0	2.3	5.8	-2.4	0.2	0.1	-1.6	-1.6	1.4	-0.6	-2.2
Comparative height size at age 10	0.6	3.1	10.4	0.1	-0.1	-2.4	-1.7	3.2	-1.4	1.4	-1.3
Number of full sisters	1.3	1.6	4.9	2.2	-1.0	0.5	-0.3	1.7	-1.0	1.3	0.9
Suffer from ‘nerves’	0.4	0.7	2.4	-0.9	0.7	-1.1	-0.5	0.1	0.6	0.3	-1.5
Overall health rating	0.5	1.1	4.0	-0.4	-2.0	0.5	0.5	0.7	0.8	0.7	1.6
Chest pain or discomfort	1.2	1.7	5.0	1.7	-0.2	0.2	0.6	2.2	-0.3	0.3	2.2
Had major operations	0.4	0.4	1.1	-0.6	-0.9	1.0	-0.6	-0.2	0.0	0.8	0.3
Age at last live birth	0.2	0.3	1.5	-0.5	-0.4	0.1	-0.5	-1.2	-0.7	-0.1	-0.1
Family relationship satisfaction	1.3	1.6	6.1	1.0	-0.0	-0.0	2.2	-0.1	0.6	-0.7	2.5
Leg pain on walking	0.3	0.3	1.1	0.6	0.8	-0.2	0.1	1.0	-0.7	0.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.8	1.1	-0.4	0.2	0.6	1.3	-0.5	-0.4	0.2
Commuting to job workplace: Car/motor vehicle	1.5	1.8	4.0	-1.0	-2.0	-1.2	-1.7	-0.5	1.0	1.9	0.3
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.5	-0.0	1.6	0.9	-0.9	-0.2	-1.3	-0.1	-1.2
Medication: Aspirin	0.8	1.0	3.2	0.3	0.6	0.4	1.0	1.7	-0.4	-1.8	-0.7
Supplements: Vitamin C	0.3	0.4	1.3	-0.2	-0.7	0.7	-0.2	-0.2	1.1	0.8	0.1
Knee pain experienced in last month	0.5	0.8	2.4	0.9	-0.6	0.2	1.3	1.0	0.6	0.3	1.5
Hypertension (Self-reported)	0.3	0.9	3.6	0.7	-0.8	1.9	0.3	1.2	-0.5	0.7	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.9	0.2	-1.4	-0.2	-0.3	-0.5	-0.1	0.8	1.4
Illnesses of father: Heart disease	0.3	0.5	1.7	-1.3	-0.5	-0.1	0.0	-0.8	0.3	-0.7	-0.6
Illnesses of siblings: Diabetes	0.2	0.2	0.9	-1.0	-0.5	-0.1	-0.2	0.4	0.1	0.3	0.6
Smoking status: Previous	0.1	0.1	0.3	0.0	-0.2	-0.1	-0.4	0.0	0.3	-0.5	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.7	0.5	0.7	-1.3	0.1	-0.3	-0.3	0.0	-0.9
Whole body fat-free mass	1.0	5.4	18.1	2.6	1.0	-0.3	2.2	4.3	-2.5	-0.4	2.4
Leg fat-free mass (right)	1.2	6.3	17.6	3.0	1.4	0.2	2.9	4.2	-2.4	-0.9	2.6
Arm fat percentage (left)	2.1	8.3	22.9	3.4	1.6	-0.0	3.2	4.8	-0.8	-0.3	4.3
Average weekly red wine intake	0.3	0.4	0.8	0.4	-0.8	0.4	-0.9	0.8	0.3	0.3	0.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.1	-0.9	0.3	-1.5	-0.0	-0.9	-0.4	-0.9	-0.5
Mood swings	0.8	1.4	5.6	0.2	0.3	-0.6	-0.9	2.4	0.2	1.4	-1.6
Loneliness, isolation	1.5	2.1	8.4	2.9	1.2	1.2	1.1	1.1	-0.3	-0.1	1.7
Long-standing illness, disability or infirmity	0.8	1.3	4.9	0.0	-0.9	2.2	-1.1	0.0	-0.4	1.6	0.9
Ever had bowel cancer screening	1.2	1.4	5.2	-1.3	-0.6	-0.8	-2.3	-0.9	0.5	1.4	-0.5
Diabetes diagnosed by doctor	0.5	0.7	2.3	0.5	-0.8	1.5	1.0	0.3	-0.2	0.8	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.5	-0.0	1.0	0.4	-0.5	-0.3	-1.2	-0.2	-0.7
Friendships satisfaction	1.2	1.5	6.1	-0.8	-0.9	-1.0	1.0	-0.6	2.5	0.5	1.5
Qualifications: nursing, teaching	2.3	3.6	9.4	0.8	3.1	0.2	-1.1	1.5	-2.0	-1.9	-2.7
Commuting to job workplace: Walk	0.7	0.8	2.8	0.2	-0.8	1.1	0.9	-0.9	-0.1	0.1	1.7
Eye problems/disorders: Cataract	0.6	0.6	2.7	-0.1	1.6	1.1	-0.0	0.6	-0.5	-0.8	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	3.2	-0.1	1.6	1.7	0.4	-1.5	-0.6	-1.8	-0.4
Medication for cholesterol	0.7	1.0	3.3	-1.3	0.6	-1.8	-0.2	-0.5	1.1	-0.6	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	4.6	-0.5	-2.1	0.0	-1.2	-1.4	-0.6	0.9	0.1
Back pain experienced in last month	0.3	0.5	2.0	0.4	-0.3	-0.7	-0.0	1.4	-0.1	1.1	-0.2
Mineral and other dietary supplements	0.3	0.4	1.2	-0.3	0.5	0.1	-0.7	0.7	-0.3	1.1	0.5
Breast cancer (self-reported)	0.6	0.7	2.1	0.2	-1.0	0.3	-1.1	-1.0	-0.4	1.5	-0.4
Asthma (self-reported)	0.7	1.3	5.2	2.2	0.2	0.2	0.3	2.3	-0.5	-0.3	0.3
Osteoporosis (self-reported)	0.8	1.0	2.6	-0.4	0.2	-1.2	-0.7	1.5	-0.5	1.6	-0.6
Osteoarthritis (self-reported)	1.3	1.7	11.4	0.1	0.7	3.4	0.5	-0.8	-0.7	-0.4	-0.4
Medication: Aspirin	1.0	1.3	4.9	0.1	0.6	0.6	1.3	1.5	-0.3	-2.2	-0.6
Medication: Gliclazide	0.3	0.4	1.1	-0.4	-1.0	0.8	0.5	-0.1	0.0	-0.4	0.8
Illnesses of father: None of the above (group 1)	0.5	0.7	2.7	-0.2	-0.9	-0.7	-1.6	-0.8	0.6	0.5	-0.1
Smoking status: Current	1.8	2.9	8.8	2.2	0.9	0.6	3.0	1.7	-0.2	-1.0	2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	3.9	13.6	-1.8	-2.4	2.0	-1.3	-3.7	-1.2	1.2	-0.4
Whole body water mass	0.9	5.2	16.7	2.6	1.0	-0.3	2.2	4.1	-2.5	-0.5	2.4
Leg predicted mass (right)	1.1	6.1	17.2	3.0	1.3	0.1	2.7	4.2	-2.5	-0.8	2.5
Arm fat mass (left)	2.5	10.2	29.2	3.9	1.6	-0.1	3.5	5.4	-1.4	-0.4	4.6
Number of self-reported non-cancer illnesses	1.5	2.5	6.3	1.5	-1.1	1.6	-0.7	1.6	-0.5	2.5	2.2
Average weekly champagne plus white wine intake	1.0	1.4	2.6	-1.4	-1.2	-0.9	-1.6	-0.5	0.4	1.4	-1.4
Miserableness	0.5	0.9	3.3	0.3	-0.1	-1.2	-0.1	1.8	0.4	-0.2	-1.4
Guilty feelings	0.6	0.9	3.2	1.8	-0.1	0.7	0.9	1.3	-0.3	1.0	-0.3
Wears glasses or contact lenses	0.4	0.5	1.8	-1.0	-1.4	-0.4	-0.3	-0.4	0.2	0.6	-0.5
Ever taken oral contraceptive pill	1.2	1.3	3.8	1.2	-1.4	0.6	-1.3	0.5	0.6	2.0	0.5
Hearing aid user	0.8	0.9	3.3	1.1	-0.4	1.8	-0.7	0.6	-0.8	0.4	0.7
Mother’s age at death	1.6	2.0	8.1	-0.1	2.8	-0.7	-0.6	0.6	-1.7	-1.2	-1.4
Financial situation satisfaction	0.5	0.6	1.5	1.2	-0.2	0.3	1.2	0.2	0.3	0.4	1.2
Tinnitus: Yes, now most or all of the time	0.9	1.1	2.9	0.6	1.0	1.7	0.8	-0.2	-1.5	-0.8	0.9
Commuting to job workplace: Public transport	0.5	0.6	2.0	-1.0	-0.1	-0.0	-0.0	0.2	-0.6	-1.2	-1.4
Eye problems/disorders: Glaucoma	0.3	0.3	0.8	0.1	0.4	0.9	-0.7	-0.3	-0.3	-0.7	-0.5
Medication: Blood pressure	0.2	0.4	2.2	0.4	-0.2	1.5	-0.1	-0.2	-0.9	0.2	-0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.6	0.6	0.5	0.5	0.1	0.0	-0.8	-0.3	-0.6
Supplements: Fish oil (including cod liver oil)	1.0	1.3	4.2	-0.7	-0.8	-0.4	0.2	-1.8	0.6	-2.1	-1.2
High cholesterol (Self-reported)	0.3	0.6	1.3	-0.9	-0.4	0.1	1.1	-0.0	1.0	-1.0	0.6
Medication: Bendroflumethiazide	0.1	0.2	0.3	-0.0	-0.5	-0.4	-0.2	0.5	0.3	0.5	0.5
Medication: Paracetamol	0.7	1.1	2.2	-1.4	-1.1	-0.9	1.3	-1.5	1.1	-0.3	0.5
Medication: Lisinopril	0.8	1.1	3.0	0.3	-1.7	0.6	-1.0	0.2	0.3	1.7	1.0
Medication: Atorvastatin	1.6	2.0	4.3	1.4	0.4	2.0	0.9	2.1	-1.6	1.1	1.2
Illnesses of father: High blood pressure	0.6	0.7	1.5	0.9	0.5	1.2	0.6	1.0	-1.1	0.5	0.1
Alcohol drinker status: Never	0.8	0.9	3.3	-1.8	-0.1	-1.3	-0.4	0.3	0.6	-0.5	-1.2
Ever smoked	0.2	0.3	1.4	0.6	-1.2	0.9	-0.2	-0.1	0.3	0.1	0.3
Basal metabolic rate	1.3	6.9	21.6	3.1	1.1	-0.3	2.7	4.7	-2.4	-0.5	3.1
Leg fat percentage (left)	2.7	9.6	26.2	3.9	1.1	-0.2	3.4	5.1	-0.3	-0.1	4.8
Arm fat-free mass (left)	1.1	5.6	17.1	2.7	0.9	-0.7	2.7	4.1	-1.8	-0.3	3.0
Number of operations (self-reported)	1.1	1.6	4.8	-0.0	1.3	0.8	-2.2	1.0	-1.6	1.1	-0.9
Average weekly beer plus cider intake	0.8	1.1	2.1	0.4	-1.3	-1.1	1.5	1.3	0.7	0.1	1.4
Irritability	0.7	1.2	4.3	-1.2	1.4	0.2	0.7	-0.4	0.9	-0.9	-2.1
Risk taking	0.6	0.9	3.0	0.2	0.1	-0.4	-0.5	1.6	-0.7	-0.7	-1.7
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.5	0.4	1.6	1.1	-0.2	-0.9	-1.0	-0.4	0.7
Fractured/broken bones in last 5 years	1.8	2.3	7.0	-0.1	-2.1	0.6	-1.1	-1.7	1.6	2.6	0.0
Age started oral contraceptive pill	0.9	1.2	3.1	0.2	0.2	0.3	-1.4	0.1	-1.3	1.8	-1.5
Diastolic blood pressure, automated reading	0.3	0.9	2.2	-1.2	-1.4	-0.0	0.8	-0.0	1.5	0.1	1.0
Ever depressed for a whole week	0.4	0.4	1.5	1.2	-0.7	0.2	-0.3	0.8	-0.7	0.3	0.5
Unable to work because of sickness or disability	0.6	0.8	3.7	-1.9	-0.4	0.6	-0.7	-0.2	0.1	0.8	-0.8
Commuting to job workplace: Cycle	0.6	0.7	1.6	0.1	-1.2	1.2	-0.1	-0.4	0.4	0.8	1.2
Myopia	0.8	1.2	3.6	-1.9	-0.8	-0.9	0.5	-1.5	1.3	0.1	-0.6
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.0	-0.6	1.1	-1.5	0.1	-1.7	0.4	-1.4	-0.5
Cholesterol lowering medication	0.8	1.1	3.0	1.0	0.1	0.9	1.7	0.8	-0.6	-0.6	1.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.5	-0.1	0.3	0.4	0.7	0.7	-0.2	-0.1	0.6
Pain experienced in last month	0.2	0.4	1.0	0.5	0.7	0.2	0.0	-0.4	-1.0	-0.9	0.3
Supplements: Calcium	1.1	1.3	3.7	-0.6	-1.9	-0.5	-1.5	-0.3	0.9	1.6	0.1
Basal cell carcinoma (self-reported)	0.7	0.8	1.7	-0.4	1.1	-0.8	-0.4	-1.3	-0.8	-1.3	-0.5
Heart attack/myocardial infarction (self-reported)	1.9	2.5	7.7	-1.9	-0.3	-1.8	-1.6	1.6	-0.3	0.3	-2.8
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.7	-0.4	-0.3	-0.8	0.0	0.6	0.3	-0.2	0.1
Heart disease (siblings)	0.3	0.3	0.8	-0.9	-0.6	-0.4	-0.5	0.9	0.2	0.4	-0.3
Alcohol drinker status: Previous	0.5	0.6	3.7	0.4	-0.6	1.9	0.5	0.3	0.2	0.0	0.6
Pack years of smoking	1.0	1.5	4.4	1.9	0.4	-0.2	1.3	2.1	-0.3	0.3	1.5
Impedance of whole body	0.6	3.0	6.3	-1.7	-0.8	-2.0	-2.4	-0.9	1.8	0.6	-2.5
Leg fat mass (left)	3.1	12.1	35.2	4.4	1.6	0.1	3.7	5.9	-1.8	-0.6	4.8
Arm predicted mass (left)	1.2	5.9	17.8	2.6	1.0	-0.6	2.9	4.2	-1.9	-0.6	3.0