[Hub]/) : Traits : BMI : ← →

chr4:24,470,143-26,118,755

Best TWAS P=2.44e-14 · Best GWAS P=5.09e-13 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ANAPC4	0.11	0.06	bslmm	562	0.09	6.4e-11	6.6	5.3	9.1e-08	0.83	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ZCCHC4	0.07	0.01	blup	568	0.02	3.1e-03	6.7	5.5	3.7e-08	0.68	0.13	0.76	FALSE
3	GTEx	Adipose Subcutaneous	ANAPC4	0.32	0.40	lasso	13	0.40	7.3e-35	7.2	6.9	4.8e-12	0.99	0.00	1.00	FALSE
4	GTEx	Artery Aorta	ANAPC4	0.40	0.43	lasso	5	0.42	5.4e-25	7.2	7.2	6.6e-13	1.00	0.00	1.00	FALSE
5	GTEx	Artery Coronary	ANAPC4	0.42	0.11	lasso	14	0.08	9.7e-04	6.7	5.5	4.5e-08	0.83	0.01	0.98	FALSE
6	GTEx	Artery Tibial	ANAPC4	0.37	0.42	enet	48	0.46	1.0e-39	7.2	6.8	1.2e-11	0.94	0.00	1.00	FALSE
7	GTEx	Brain Cortex	ANAPC4	0.33	0.24	enet	23	0.26	7.5e-08	6.6	5.9	3.9e-09	0.86	0.04	0.96	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	ANAPC4	0.41	0.15	enet	30	0.20	4.2e-06	6.8	6.0	2.5e-09	0.81	0.06	0.92	FALSE
9	GTEx	Brain Putamen basal ganglia	ANAPC4	0.25	0.03	lasso	7	0.04	3.6e-02	6.8	6.2	6.2e-10	0.90	0.06	0.49	FALSE
10	GTEx	Breast Mammary Tissue	ANAPC4	0.49	0.42	lasso	8	0.42	1.5e-23	7.2	7.6	2.4e-14	0.99	0.00	1.00	TRUE
11	GTEx	Breast Mammary Tissue (Male)	ANAPC4	0.49	0.30	enet	14	0.26	8.6e-07	7.2	7.3	4.1e-13	0.90	0.01	0.99	FALSE
12	GTEx	Breast Mammary Tissue (Female)	ANAPC4	0.30	0.28	lasso	8	0.19	2.2e-06	7.2	7.0	1.9e-12	0.99	0.01	0.99	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	ZCCHC4	0.38	0.13	lasso	10	0.12	1.0e-04	6.6	5.7	9.0e-09	0.82	0.18	0.66	FALSE
14	GTEx	Cells Transformed fibroblasts	ANAPC4	0.14	0.20	lasso	8	0.19	2.3e-14	7.2	7.2	7.3e-13	1.00	0.00	1.00	FALSE
15	GTEx	Cells Transformed fibroblasts	ZCCHC4	0.13	0.03	enet	13	0.05	1.0e-04	1.5	5.2	1.6e-07	0.73	0.43	0.48	FALSE
16	GTEx	Colon Sigmoid	ANAPC4	0.28	0.27	enet	12	0.24	5.7e-09	6.6	6.5	6.8e-11	0.96	0.01	0.99	FALSE
17	GTEx	Colon Transverse	ANAPC4	0.36	0.38	lasso	8	0.41	5.5e-21	7.2	6.5	7.2e-11	0.98	0.01	0.99	FALSE
18	GTEx	Esophagus Gastroesophageal Junction	ANAPC4	0.26	0.22	enet	21	0.20	8.3e-08	7.2	6.6	4.5e-11	0.95	0.01	0.99	FALSE
19	GTEx	Esophagus Mucosa	ANAPC4	0.33	0.23	lasso	10	0.21	4.6e-14	7.2	7.0	3.3e-12	0.99	0.00	1.00	FALSE
20	GTEx	Esophagus Muscularis	PI4K2B	0.14	0.05	lasso	7	0.05	4.2e-04	4.3	5.6	2.0e-08	0.68	0.33	0.63	FALSE
21	GTEx	Esophagus Muscularis	ANAPC4	0.37	0.40	lasso	8	0.39	2.4e-25	7.2	7.1	9.1e-13	0.99	0.00	1.00	FALSE
22	GTEx	Heart Atrial Appendage	ANAPC4	0.18	0.12	lasso	9	0.10	3.4e-05	7.2	7.1	1.0e-12	0.99	0.01	0.99	FALSE
23	GTEx	Heart Left Ventricle	ANAPC4	0.13	0.10	lasso	7	0.07	1.6e-04	7.0	7.4	1.9e-13	0.99	0.01	0.99	FALSE
24	GTEx	Liver	ANAPC4	0.25	0.14	enet	16	0.02	1.1e-01	7.2	6.4	1.6e-10	0.80	0.01	0.93	FALSE
25	GTEx	Lung	ANAPC4	0.14	0.14	enet	11	0.13	4.4e-10	6.6	6.9	6.9e-12	0.98	0.02	0.98	FALSE
26	GTEx	Muscle Skeletal	ANAPC4	0.24	0.24	lasso	6	0.32	1.3e-32	7.2	6.2	7.4e-10	0.91	0.00	1.00	FALSE
27	GTEx	Muscle Skeletal	ZCCHC4	0.13	0.11	lasso	4	0.11	2.7e-11	5.5	6.0	1.4e-09	0.87	0.13	0.87	FALSE
28	GTEx	Nerve Tibial	ANAPC4	0.35	0.43	enet	14	0.43	4.3e-33	7.2	7.3	2.8e-13	0.99	0.00	1.00	FALSE
29	GTEx	Pancreas	ANAPC4	0.35	0.21	lasso	13	0.19	1.8e-08	6.6	7.1	1.3e-12	0.93	0.02	0.98	FALSE
30	GTEx	Pituitary	ANAPC4	0.38	0.12	lasso	7	0.07	8.8e-03	7.0	7.3	3.8e-13	0.92	0.01	0.95	FALSE
31	GTEx	Skin Not Sun Exposed Suprapubic	ANAPC4	0.40	0.45	enet	28	0.44	1.5e-26	7.2	6.6	4.0e-11	0.98	0.00	1.00	FALSE
32	GTEx	Skin Sun Exposed Lower leg	ANAPC4	0.27	0.34	enet	23	0.34	4.4e-29	7.2	7.5	8.3e-14	0.98	0.00	1.00	FALSE
33	GTEx	Spleen	ANAPC4	0.41	0.28	enet	14	0.36	3.2e-10	5.0	6.3	2.2e-10	0.93	0.01	0.99	FALSE
34	GTEx	Stomach	ANAPC4	0.28	0.34	lasso	5	0.32	5.1e-16	7.2	7.1	1.2e-12	1.00	0.00	1.00	FALSE
35	GTEx	Testis	ANAPC4	0.12	0.10	lasso	5	0.08	2.3e-04	7.2	7.2	7.3e-13	1.00	0.01	0.99	FALSE
36	GTEx	Thyroid	ANAPC4	0.27	0.23	lasso	14	0.26	8.0e-20	7.2	6.6	4.4e-11	0.95	0.01	0.99	FALSE
37	METSIM	Adipose	ANAPC4	0.19	0.28	bslmm	552	0.28	3.5e-42	7.2	6.7	2.0e-11	0.97	0.00	1.00	FALSE
38	ROSMAP	Brain Pre-frontal Cortex	ANAPC4	0.19	0.27	lasso	11	0.27	3.5e-35	7.2	6.9	4.2e-12	0.98	0.00	1.00	FALSE
39	YFS	Blood	ANAPC4	0.22	0.28	bslmm	530	0.32	4.5e-109	7.2	6.5	6.1e-11	0.94	0.00	1.00	FALSE
40	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZCCHC4	0.02	0.01	blup	83	0.00	4.5e-02	5.5	5.7	1.4e-08	0.89	0.10	0.84	FALSE
41	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ANAPC4	0.03	0.05	enet	10	0.04	1.9e-05	7.2	7.4	1.2e-13	0.93	0.01	0.99	FALSE
42	The Cancer Genome Atlas	Brain Lower Grade Glioma	ANAPC4	0.07	0.01	blup	69	0.03	2.9e-04	7.2	6.1	1.2e-09	0.79	0.01	0.99	FALSE
43	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ANAPC4	0.05	0.00	blup	69	0.01	7.5e-03	5.3	5.6	2.5e-08	0.83	0.02	0.89	FALSE
44	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ANAPC4	0.10	0.04	lasso	5	0.06	1.1e-03	5.3	6.0	1.9e-09	0.92	0.03	0.70	FALSE
45	The Cancer Genome Atlas	Thyroid Carcinoma	ANAPC4	0.06	0.02	lasso	3	0.03	1.1e-03	3.6	5.2	2.4e-07	0.70	0.10	0.36	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	ZCCHC4	0.07	0.06	enet	12	0.09	1.7e-09	6.7	6.0	1.7e-09	0.86	0.12	0.88	FALSE