Best TWAS P=1.9e-08 · Best GWAS P=5.04e-14 conditioned to 2.78e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | FAM114A1 | 0.07 | -0.01 | lasso | 4 | 0.01 | 0.17400 | 3.6 | 5.6 | 1.9e-08 | -0.46 | 0.05 | 0.12 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | TLR10 | 0.09 | 0.06 | lasso | 2 | 0.06 | 0.00023 | 5.1 | -5.3 | 1.0e-07 | 0.43 | 0.01 | 0.93 | FALSE |
| 3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | TLR1 | 0.13 | 0.13 | enet | 3 | 0.08 | 0.00259 | 4.7 | -5.2 | 2.4e-07 | 0.41 | 0.03 | 0.47 | FALSE |