Hub : Genes

PI4K2B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0900 0.0380 3.9e-03 -0.001 NA 0.004 NA 0.006 4.2e-01 NA 1.4e-01 NA 1.0e-01
2 GTEx Brain Cerebellum 0.2850 0.0880 4.4e-04 0.126 NA 0.108 NA 0.001 1.5e-04 NA 4.3e-04 NA 3.0e-01
3 GTEx Brain Frontal Cortex BA9 0.5974 0.1174 3.1e-03 0.003 NA 0.147 NA 0.139 2.6e-01 NA 1.0e-04 NA 1.6e-04
4 GTEx Breast Mammary Tissue 0.2430 0.0750 3.9e-04 0.014 NA 0.034 NA 0.001 6.3e-02 NA 7.3e-03 NA 2.7e-01
5 GTEx Breast Mammary Tissue (Male) 0.0264 0.0763 4.0e-01 0.024 NA -0.013 NA -0.008 9.3e-02 NA 8.9e-01 NA 5.3e-01
6 GTEx Breast Mammary Tissue (Female) 0.1322 0.0869 8.0e-02 -0.005 NA -0.006 NA 0.037 4.9e-01 NA 5.2e-01 NA 2.9e-02
7 GTEx Cells Transformed fibroblasts 0.1670 0.0480 2.6e-04 0.099 NA 0.063 NA 0.080 7.8e-08 NA 1.7e-05 NA 1.4e-06
8 GTEx Colon Sigmoid 0.3270 0.0830 6.1e-05 0.040 NA 0.000 NA 0.044 1.5e-02 NA 3.2e-01 NA 1.2e-02
9 GTEx Esophagus Muscularis 0.1450 0.0450 4.7e-05 0.051 NA 0.025 NA 0.052 4.7e-04 NA 1.2e-02 NA 4.3e-04
10 GTEx Muscle Skeletal 0.1424 0.0453 3.0e-04 0.053 NA 0.009 NA 0.025 6.6e-06 NA 4.2e-02 NA 1.4e-03
11 GTEx Thyroid 0.0850 0.0350 2.6e-03 0.074 NA 0.026 NA 0.045 2.5e-06 NA 4.4e-03 NA 2.1e-04
12 ROSMAP Brain Pre-frontal Cortex 0.3046 0.0550 7.0e-07 0.196 0.091 0.183 0.192 0.187 1.4e-24 9.4e-12 5.5e-23 4.5e-24 1.8e-23
13 TCGA Head and Neck Squamous Cell Carcinoma 0.0405 0.0215 6.0e-03 0.012 0.021 0.012 NA 0.012 1.5e-02 1.9e-03 1.4e-02 NA 1.5e-02
14 TCGA Brain Lower Grade Glioma 0.0571 0.0325 1.8e-03 0.010 0.030 0.029 NA 0.015 2.5e-02 1.9e-04 2.9e-04 NA 7.7e-03
15 TCGA Prostate Adenocarcinoma 0.0501 0.0272 2.5e-03 0.033 0.015 0.012 NA 0.017 1.8e-04 8.4e-03 1.9e-02 NA 5.6e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 1.1 1.8 6.5 -2.6 -1.1 -0.0 -1.9 -1.6 -0.4 1.3 1.2 -0.1 -2.3 0.3 -1.3 0.8 -1.3 -0.1
Bipolar Disorder or Schizophrenia 0.4 1.0 5.3 -0.8 -1.0 0.5 -0.6 0.8 -0.6 0.6 0.4 -0.3 -2.3 -0.4 -2.3 0.1 -1.0 -0.3
Depressed Affect (Nagel 2018) 0.3 0.7 3.3 0.3 -0.1 0.7 0.1 0.6 0.4 -0.7 -1.4 -0.4 1.0 -0.2 1.8 -0.4 1.3 -0.6
Depression (Nagel 2018) 0.5 0.7 2.3 -0.3 1.0 -1.3 -0.5 1.3 -0.8 -1.3 0.6 0.8 0.0 -0.0 -0.5 -1.5 -0.5 -0.6
Intelligence (Savage-Jansen 2018) 1.2 3.8 16.5 0.6 -2.2 -2.1 -0.6 0.9 -0.3 -0.0 -3.5 -4.1 -1.9 -2.6 2.0 0.2 -0.7 -1.4
Neuroticism (Nagel 2018) 0.6 1.5 6.7 -0.1 -2.6 -0.7 -1.6 0.4 -0.3 1.0 -1.6 -1.7 -1.2 -1.0 0.2 0.5 -1.1 -1.2
Schizophrenia (2018) 0.4 0.9 4.1 1.1 -0.4 0.7 0.8 2.0 -0.4 -0.3 -0.5 -0.3 -1.1 -0.8 -1.9 -0.6 -0.3 -0.3
Schizophrenia vs Biploar Disorder 1.0 1.3 7.1 2.7 0.6 -0.6 2.1 0.0 0.8 0.4 0.4 0.4 1.7 -1.4 -0.6 0.5 -0.1 -0.2
Worry (Nagel 2018) 1.4 3.0 11.6 -0.7 -3.4 -0.6 -2.8 -0.5 -1.2 2.0 -1.0 -1.6 -2.8 -0.5 -0.4 1.1 -2.2 -0.7
Alzheimer’s Disease (in mother) 0.4 0.4 1.9 0.4 -0.5 -0.2 0.0 -0.3 0.8 0.1 -0.1 0.1 -0.5 1.3 1.4 0.7 -0.7 0.7
Alzheimer’s Disease (in father) 2.2 2.4 8.2 0.2 -0.1 1.7 -0.8 0.2 -2.3 -2.9 -2.0 -1.4 -1.4 -0.4 0.8 -2.8 -0.0 -1.3
Alzheimer’s Disease (including proxy) 0.7 1.0 3.4 0.8 -0.0 0.6 -0.7 -1.2 -0.6 -1.8 -1.5 -0.9 -1.0 0.8 1.5 -1.3 -0.2 -0.3
Crohns Disease (2017) 0.7 1.5 4.8 0.4 2.2 1.0 1.9 0.5 1.2 -0.8 1.6 1.5 0.6 -0.3 -1.3 -0.2 1.6 1.0
Irritable Bowel Disease (IBD) 0.3 0.8 4.0 0.0 1.2 -0.3 1.4 1.2 0.7 -1.0 -0.1 0.3 -0.3 -0.4 -0.4 -0.6 2.0 1.0
Ulcerative Colitis (UC) 0.6 1.0 3.4 -0.4 0.3 -1.4 0.1 1.7 -0.9 -1.1 -1.0 -0.4 -1.9 -0.1 -0.1 -1.1 1.2 0.9
Major Depression (MDD) 0.4 0.5 1.5 0.0 -0.8 0.2 0.4 0.3 -0.8 0.8 -0.5 -0.2 0.3 1.2 1.0 1.2 -0.9 0.4
Reaction Time 1.3 2.5 7.6 2.0 -1.4 1.1 -0.1 1.4 0.6 0.9 -1.3 -1.3 0.3 -2.8 -2.5 0.0 -2.3 -2.1
Verbal and Numeric Reasoning (VNR) 0.6 1.5 7.3 0.8 -0.3 -1.2 0.9 0.5 -0.1 -0.4 -2.4 -2.7 -0.6 -1.3 2.1 0.2 0.5 -0.3
Breast Cancer 0.5 1.3 4.1 -0.1 -2.0 -1.3 -0.3 0.1 1.0 1.7 -1.4 -1.4 0.4 -0.5 -0.1 1.6 -1.5 0.0
Ovarian Cancer 0.5 0.6 3.2 -0.3 0.4 -0.0 -0.1 -0.4 0.0 -1.1 -1.0 -0.7 -0.4 0.2 1.8 -0.5 1.5 0.4
Prostate Cancer 0.8 1.1 3.0 1.4 1.6 1.3 1.2 -0.3 0.3 -1.7 -0.3 0.6 -0.7 0.1 0.3 -1.5 1.3 0.3
Age at First Birth 0.7 1.0 5.4 1.1 -0.2 1.0 0.6 2.3 -1.3 -0.5 -1.4 -1.3 -0.5 -0.4 0.9 -0.5 0.1 -0.3
Bipolar Disorder (2011) 1.0 1.0 5.1 -0.7 -0.1 -0.6 -1.0 0.0 -1.5 0.9 0.6 0.8 -2.3 1.3 -0.9 0.4 0.0 0.9
Body Mass Index (BMI) (2010) 1.7 2.3 12.7 1.1 1.5 -0.4 2.4 0.7 1.7 -1.0 1.0 1.9 3.6 0.9 0.2 -0.1 1.6 0.1
Coronary Artery Disease (CAD) 0.6 0.8 3.3 1.3 1.8 -1.1 0.6 0.0 -0.0 -0.9 0.4 0.8 0.5 -0.1 -1.1 -1.0 0.7 0.4
Crohns Disease (2012) 1.6 2.6 10.0 0.5 3.2 -0.8 2.0 0.3 0.7 -1.5 2.9 2.4 0.3 0.4 -1.5 -0.9 1.4 0.9
Mean Putamen Volume 1.5 1.7 6.2 0.5 -1.0 -1.4 -0.1 -0.8 1.6 -1.1 -2.3 -2.5 0.5 -1.5 0.8 -0.8 0.8 -1.4
Fasting Glucose 0.6 0.7 2.6 -0.2 -0.7 -0.6 -1.0 0.9 -1.0 1.6 -0.1 0.2 -0.9 0.7 0.5 1.1 -0.1 1.1
HbA1C 1.6 1.8 5.1 1.9 0.1 -0.6 2.0 0.2 2.3 1.1 -0.1 1.2 1.6 1.1 0.2 2.2 -0.0 1.3
HDL Cholesterol 0.6 1.0 4.3 -1.0 -0.9 0.3 -2.1 -1.1 -1.1 0.9 0.3 -0.0 -1.2 -0.1 -0.5 0.4 -1.6 0.0
LDL Cholesterol 0.4 0.6 2.2 0.7 1.1 0.1 -0.5 0.3 -1.5 -0.8 0.5 0.7 0.5 0.5 0.7 -1.0 0.9 0.2
Lupus 1.0 1.5 3.8 1.6 1.8 -1.3 2.0 1.0 1.5 -0.5 1.5 1.5 -0.1 0.2 -0.4 -0.6 1.6 -0.1
Neuroticism (2016) 0.8 1.1 3.4 1.2 -0.8 -1.6 -1.9 0.1 -1.8 1.1 -0.0 -0.2 -0.4 -0.8 -0.8 -0.8 -1.1 -1.1
Primary Biliary Cirrhosis 0.9 1.3 5.3 0.7 1.7 0.4 -0.1 0.3 -0.6 -1.8 1.1 1.5 -1.0 0.6 -1.0 -2.3 0.7 0.5
Rheumatoid Arthritis 0.2 0.3 1.0 -1.0 -0.3 0.6 0.3 0.5 0.4 -0.8 0.1 -0.3 0.3 -0.3 0.4 -0.7 -0.4 -0.8
Schizophrenia (2014) 0.7 1.6 6.6 -0.1 -0.6 1.8 0.3 0.0 -1.0 -0.5 -0.1 -0.6 -1.7 -1.8 -2.6 -1.3 -1.3 -1.4
Triglycerides 0.8 1.3 3.2 1.6 1.6 0.5 -0.3 1.5 -1.8 -0.8 0.7 1.2 0.4 1.5 0.5 -0.7 1.0 1.4
Type 2 Diabetes (T2D) (2012) 0.9 1.0 3.1 -0.0 0.7 -0.0 1.0 0.0 0.4 -1.4 0.5 0.6 1.3 -1.6 -0.6 -1.6 0.5 -1.8
Ulcerative Colitis 0.7 1.1 4.1 -0.4 -0.1 -2.0 -0.4 0.0 -0.3 -1.0 -0.9 -0.9 -1.8 -1.1 -0.0 -1.5 1.3 -0.6
Blood Eosinophil Count 0.1 1.1 4.5 1.1 0.1 1.2 1.2 1.1 0.9 0.3 -0.6 -0.1 1.1 -1.0 1.7 -0.0 2.1 -0.5
Blood Platelet Count 0.2 2.1 6.6 1.5 2.1 -1.1 1.7 -1.4 1.4 -0.4 0.9 2.0 2.6 1.2 -0.2 1.1 0.9 1.5
Blood Red Count 0.3 2.8 5.7 1.1 0.0 2.1 1.8 1.6 1.3 -2.4 -1.9 -1.7 1.4 -1.9 0.4 -2.0 0.9 -2.3
Blood White Count 0.6 4.2 16.7 1.1 2.6 -0.7 3.0 0.6 1.6 -1.2 2.1 2.9 4.1 0.5 0.5 -0.7 3.2 0.4
Heel T-Score 0.1 0.7 2.8 -0.9 -0.5 1.0 -0.8 1.7 -0.9 -0.7 -0.3 -0.0 0.0 0.5 0.0 -0.9 -1.5 -0.5
BMI 1.7 10.0 31.5 3.1 4.5 1.6 4.6 2.5 2.4 -1.4 3.8 5.6 4.0 2.0 -2.7 -0.8 2.6 1.1
Height 0.1 1.8 8.0 -1.2 -1.3 -0.6 -0.7 -0.6 0.7 -0.4 -2.1 -2.8 -1.8 -1.7 0.3 -0.4 0.5 -1.8
Waist Hip Ratio (WHR) 0.6 2.5 7.1 -1.0 -2.7 1.6 -0.4 0.3 1.4 2.0 -2.0 -2.2 0.2 -2.2 0.9 1.5 -0.2 -2.0
Systolic Blood Pressure 0.5 2.5 12.7 -1.0 1.0 1.3 -1.5 -0.6 -1.8 -2.4 1.0 -0.1 -1.9 -1.5 -0.1 -3.6 1.4 -1.3
Smoking Status 0.2 0.5 1.6 -0.8 -1.0 -0.9 0.3 0.2 0.6 -0.1 -0.9 -0.4 1.3 0.5 0.1 0.6 -0.9 0.3
Allergy or Eczema 0.4 1.2 6.0 0.2 -0.7 -1.0 -1.3 -0.5 -0.8 1.1 0.7 0.5 -1.2 1.2 -0.3 1.2 -2.5 0.8
Cardiovascular Disease 0.7 2.3 7.6 2.3 2.1 -0.5 0.4 -0.1 0.4 -2.0 1.4 2.3 0.6 0.3 -0.5 -2.2 2.8 -0.0
Hypothyroidism (self reported) 0.5 1.1 7.5 -0.5 -0.9 1.3 -0.3 0.7 -0.1 0.6 -0.4 0.5 -0.6 1.1 -1.3 0.9 -2.7 0.8
Respiratory disease 0.6 1.3 3.4 -0.9 -1.2 0.5 -1.1 -1.2 -0.1 1.8 1.4 0.3 1.2 -0.1 -0.7 1.7 -1.8 -0.2
Type 2 Diabetes (T2D) (2018) 1.9 3.5 14.2 1.6 2.1 -0.1 3.8 1.5 2.7 -1.5 0.4 1.7 3.0 1.3 0.4 0.2 2.0 1.1
Lung FEV1/FVC ratio 0.4 2.2 8.4 1.8 1.5 -1.6 0.7 -0.1 0.5 -2.0 -1.0 0.2 0.6 -1.2 -0.1 -2.6 2.9 -1.4
Lung FVC 1.0 5.2 15.5 -3.0 -3.1 -0.8 -2.7 -2.6 0.2 1.0 -2.4 -3.9 -0.1 -3.3 1.2 0.4 -1.7 -2.6
Neuroticism 0.3 0.8 3.2 -0.1 -1.8 -1.1 -1.5 0.3 -0.1 1.0 -0.7 -0.8 -0.9 -0.6 0.1 0.5 -1.0 -0.6
Chronotype (morning person) 0.2 0.5 2.5 -0.2 0.6 0.1 0.6 0.5 -0.6 0.3 1.6 0.9 0.2 0.3 -0.1 0.3 1.1 0.7
Hair Pigment 0.0 1.4 4.6 1.1 1.3 1.3 1.1 0.7 1.0 -0.1 0.6 1.7 0.8 2.1 -0.1 0.8 1.2 1.7
Tanning 0.1 0.8 3.4 -0.4 -1.0 1.0 0.4 0.5 -0.4 1.9 0.6 -0.1 0.2 -1.0 -1.2 0.8 -1.5 -0.9
Hand grip strength (left) 0.5 1.4 3.0 0.6 1.2 1.0 1.5 0.3 1.1 0.8 1.7 1.6 1.7 1.0 0.4 1.2 0.9 1.2
Number of treatments/medications taken 0.9 1.6 5.3 0.0 2.0 -1.2 0.5 -0.3 -0.1 -0.8 2.3 2.1 0.1 1.6 -1.4 -0.4 -0.3 1.6
Average weekly spirits intake 0.8 1.0 2.4 -1.4 -1.4 1.0 0.2 0.3 0.8 -0.1 -1.4 -1.5 0.9 -1.0 0.9 0.1 -0.8 -1.3
Sensitivity / hurt feelings 0.9 1.5 4.7 0.4 -2.2 -1.2 -1.6 -0.1 0.6 1.8 -0.8 -1.5 -0.6 -1.3 0.3 1.3 -1.3 -1.1
Frequency of depressed mood in last 2 weeks 0.4 0.5 1.6 -1.3 0.9 -1.0 -0.2 1.3 -0.3 -0.8 0.0 0.5 0.8 -0.1 -0.1 -1.1 -0.2 -0.3
Hearing difficulty/problems: Yes 0.6 1.0 3.2 -1.0 1.3 0.6 1.4 0.2 0.9 -0.9 1.0 1.3 0.8 1.8 0.4 0.2 -0.3 1.1
Relative age of first facial hair 0.6 1.2 6.4 -2.5 -1.4 0.1 -1.6 -0.6 -0.8 1.3 -0.1 -1.1 -0.8 -0.4 1.1 0.4 -0.3 -0.3
Other serious medical condition/disability diagnosed by doctor 1.5 2.0 6.3 0.1 1.9 -0.4 1.2 -0.3 1.0 -0.4 2.3 2.2 1.2 2.5 -0.6 0.6 -0.4 2.0
Ever used hormone-replacement therapy (HRT) 1.1 1.4 9.3 0.1 0.3 -0.9 -0.2 -0.6 0.4 0.7 0.8 1.7 0.4 3.1 0.8 1.1 0.2 2.1
Ever had hysterectomy (womb removed) 0.9 1.1 4.4 0.1 0.2 0.6 -0.4 -0.0 -0.6 2.1 0.8 1.4 -0.8 1.7 -0.9 1.5 0.1 1.4
Systolic blood pressure, automated reading 0.6 1.9 9.0 -0.8 1.4 2.1 0.2 0.3 -1.6 -2.3 1.2 0.6 -0.9 -0.1 -0.1 -3.0 1.1 -0.8
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 2.7 0.3 0.5 1.1 0.1 0.9 -0.6 -0.1 0.3 0.2 -0.1 -0.8 -1.6 -0.8 -0.1 -0.4
Angina 1.0 1.3 3.6 0.0 1.6 0.8 1.9 1.3 0.9 -0.7 1.0 1.9 1.1 0.8 0.1 -0.4 1.6 0.6
Medication for hormone replacement therapy 2.2 2.4 6.6 -1.0 2.2 0.6 -0.5 -2.0 -1.0 -1.6 1.2 2.3 -0.2 2.6 0.5 -1.5 1.8 1.7
Vitamin and mineral supplements 0.4 0.6 1.6 -1.3 0.1 0.6 1.0 -0.6 0.3 0.5 0.2 -0.7 1.0 -0.7 1.2 0.8 0.9 0.3
Supplements: Zinc 0.1 0.2 0.5 -0.4 0.1 0.7 0.5 0.2 0.2 -0.2 -0.4 0.2 0.4 -0.5 -0.2 -0.3 0.4 -0.6
Medication: Co-codamol 0.7 0.8 2.4 0.9 0.4 -0.6 -0.2 -0.4 -1.4 0.6 1.5 1.1 1.2 -0.1 -1.0 -0.2 0.6 -1.1
Medication: Metformin 1.1 1.6 5.2 -0.3 0.7 -0.9 2.3 1.9 1.7 -0.1 0.9 1.2 2.0 1.4 0.6 1.0 0.1 1.1
Diabetes (father) 0.7 0.8 2.1 1.2 1.4 -0.3 1.4 -1.1 0.7 -1.3 0.7 0.1 1.4 -0.0 0.7 0.0 0.3 0.8
Diabetes (mother) 2.8 3.5 13.0 -0.8 -1.0 0.7 -1.1 0.9 -1.2 -2.0 -2.0 -2.3 -1.2 -2.6 -0.8 -3.2 -1.5 -3.6
Severe depression (siblings) 0.6 0.7 3.3 1.4 0.6 1.8 0.8 1.1 0.0 -0.8 -0.4 0.8 0.7 0.7 -0.1 -0.6 -0.4 0.2
Pack years adult smoking proportion 1.3 2.0 7.2 0.5 0.7 0.9 -1.0 -1.0 -1.8 0.1 1.1 2.1 -1.4 2.7 -2.0 -0.2 -0.6 1.8
Impedance of leg (right) 1.9 9.3 32.8 -1.5 -4.5 -0.0 -4.3 -1.9 -2.6 1.5 -4.5 -5.7 -3.0 -3.7 0.5 0.1 -2.1 -2.6
Leg fat-free mass (left) 0.8 4.2 15.0 1.3 2.8 0.5 2.5 1.2 2.8 -0.5 3.1 3.9 2.0 1.2 -2.1 -0.2 1.7 0.8
Trunk fat percentage 0.6 2.3 10.0 2.5 0.8 0.8 1.3 0.3 1.7 1.0 1.4 2.1 1.7 0.0 -3.2 0.8 -0.8 0.3
Hand grip strength (right) 0.5 1.3 4.6 0.0 1.5 1.1 1.5 -0.6 1.1 -1.4 1.6 1.0 2.1 -0.2 0.8 -0.7 1.1 -0.2
Townsend deprivation index at recruitment 0.6 0.8 3.2 -0.3 1.0 -1.8 0.5 -1.4 1.4 -0.2 0.5 1.2 0.4 0.4 -1.2 -0.0 0.3 0.4
Current tobacco smoking 0.3 0.5 1.9 -1.4 -1.1 -0.1 0.1 0.2 0.4 0.4 -0.9 0.1 0.4 0.6 0.2 0.7 -1.2 0.3
Average weekly fortified wine intake 1.3 1.5 5.4 -0.6 -1.6 -1.9 -0.8 -0.8 -0.9 -0.2 -2.3 -2.3 -1.1 -0.9 0.1 -0.3 -0.9 -0.5
Maternal smoking around birth 0.4 0.6 2.1 -1.4 -1.2 0.8 -0.9 0.8 0.4 0.8 -1.0 -0.6 0.1 -0.6 -0.0 0.5 -0.6 -1.0
Fed-up feelings 0.3 0.6 3.2 0.1 -0.1 -0.4 0.5 -0.0 1.6 0.3 -0.8 -0.1 1.8 -1.2 0.4 0.2 0.5 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 2.8 -0.2 1.3 0.1 -0.4 1.1 -1.1 -0.6 1.0 1.7 0.6 0.1 -1.4 -1.5 -0.7 -0.4
Relative age voice broke 0.9 1.3 5.3 -2.3 -1.7 0.3 -2.0 -1.5 -0.6 0.5 -0.6 -1.6 -0.9 -0.2 0.8 -0.1 -0.5 -0.6
Taking other prescription medications 0.8 1.3 4.0 0.8 1.2 -0.6 0.9 -0.9 1.5 -0.2 2.0 1.6 1.4 1.4 -0.5 0.9 -0.5 1.1
Age when periods started (menarche) 0.3 0.8 4.6 -1.2 -1.0 -2.1 -0.1 0.5 -0.4 0.9 -0.2 -0.9 -0.9 -0.4 0.2 0.9 -0.7 0.3
Bilateral oophorectomy (both ovaries removed) 2.8 3.2 16.9 -0.7 1.6 1.2 0.1 0.3 -0.9 1.4 1.9 2.9 -0.4 4.1 -0.6 1.2 0.2 3.1
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 2.0 -0.2 0.0 1.4 0.1 -0.9 1.1 -0.3 -1.2 -0.1 0.7 0.6 0.5 0.4 0.3 -0.2
Tinnitus: Yes, but not now, but have in the past 0.6 0.7 2.0 -0.3 0.8 -0.3 -1.1 -0.6 -1.4 0.8 1.0 1.4 -0.0 1.0 -1.0 -0.0 -0.4 0.2
Qualifications: CSEs or equivalent 0.6 0.8 2.6 0.2 1.0 -0.1 0.7 -1.2 1.0 0.1 1.1 1.3 1.3 -0.3 -1.6 -0.0 -0.0 0.0
Serious illness, injury or assault to yourself 1.3 1.6 4.2 -0.9 1.1 -0.8 -1.8 -0.6 -1.6 -1.0 1.6 1.3 -0.9 0.0 -2.0 -2.0 -0.5 -0.3
High blood pressure 1.0 2.9 10.9 1.0 3.3 0.0 1.3 0.6 -0.5 -1.7 2.5 3.0 0.8 1.0 -1.7 -2.0 1.6 0.8
Hayfever, allergic rhinitis or eczema 0.6 1.3 5.7 0.3 -0.7 0.5 -0.9 0.2 -0.5 1.4 -0.1 0.2 -1.6 1.4 0.5 1.8 -2.4 1.4
Multivitamins +/- minerals 0.6 0.7 2.1 1.2 1.3 -0.8 0.1 0.1 -0.8 -1.3 0.0 0.9 -0.3 1.4 -0.1 -1.0 0.4 0.8
Stomach or abdominal pain in last month 0.6 0.8 3.3 -0.1 -0.9 -1.8 -0.2 -0.6 0.7 1.3 0.3 0.3 0.7 -0.8 -1.4 0.7 -1.0 -0.8
Supplements: Glucosamine 0.4 0.5 2.5 0.0 0.4 -1.1 -0.1 -0.4 0.6 -0.8 0.4 -0.4 1.6 -0.6 0.5 -0.5 -0.2 -1.1
Diverticular disease/diverticulitis (self-reported) 0.9 1.0 5.3 1.2 -1.2 -0.3 -2.3 -1.4 -1.0 0.4 -1.2 -1.1 -0.1 -0.5 0.5 0.1 0.6 -0.3
Medication: Atenolol 0.9 1.2 4.4 1.3 1.5 -1.1 1.4 -0.3 1.2 -0.3 -0.0 1.2 1.5 -0.2 -0.5 0.1 2.1 0.4
Medication: Levothyroxine sodium 0.6 1.0 3.2 -0.7 -0.7 1.8 0.8 1.4 0.6 0.2 -0.7 0.1 -1.1 1.0 -0.8 0.7 -1.7 0.8
Sitting height 0.1 0.7 3.0 -0.9 -0.0 -0.8 0.5 0.3 1.7 -0.0 0.5 -0.4 0.8 -1.2 0.5 0.3 1.2 -0.9
Chronic bronchitis/emphysema (father) 0.7 0.8 3.7 -1.4 -0.7 1.9 -0.6 -0.2 0.3 0.7 0.6 0.1 -0.4 0.6 1.5 0.7 1.0 0.6
High blood pressure (mother) 0.5 0.8 2.3 0.3 0.2 -0.9 -0.8 -0.1 -0.3 1.0 0.8 1.2 1.2 1.5 0.8 0.8 0.6 1.2
Body mass index (BMI) 1.7 7.1 24.6 2.2 4.0 1.3 3.4 1.2 2.3 -1.3 3.8 5.0 3.2 1.4 -3.1 -1.1 1.3 0.8
Impedance of leg (left) 2.1 10.4 39.4 -1.6 -4.8 -0.1 -4.0 -2.1 -1.9 1.1 -5.1 -6.3 -2.6 -4.2 1.1 0.1 -2.3 -3.1
Leg predicted mass (left) 0.8 4.5 16.0 1.3 2.9 0.5 2.6 1.2 2.8 -0.4 3.2 4.0 2.1 1.2 -2.1 -0.2 1.7 0.8
Trunk fat mass 0.7 3.0 9.4 2.4 1.6 0.9 1.9 0.6 2.3 0.4 2.1 2.7 2.2 0.1 -3.1 0.3 0.3 0.2
Waist circumference 0.7 2.6 6.7 1.1 1.6 1.1 2.0 1.3 2.1 -0.3 2.2 2.6 2.4 -0.3 -2.2 -0.7 0.7 -0.8
Number of incorrect matches in round 0.8 1.3 4.2 -1.3 -0.8 -0.9 -1.6 -0.9 -1.1 2.0 0.6 0.2 -0.9 0.8 -0.9 1.4 -0.9 1.6
Past tobacco smoking 0.3 0.5 1.7 0.6 1.3 -0.6 0.4 -1.0 0.1 -0.2 1.0 1.3 0.2 -0.2 -0.8 -0.5 0.5 -0.2
Alcohol usually taken with meals 0.7 1.1 3.3 1.1 0.9 -1.5 0.8 0.3 -0.3 -1.0 -0.7 0.4 0.2 1.4 1.8 -0.0 1.0 1.8
Nervous feelings 1.9 3.5 10.9 -1.1 -3.3 -0.7 -2.6 0.1 -1.8 2.0 -1.7 -2.3 -2.4 -1.7 -0.9 0.3 -2.1 -1.9
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 2.6 -1.0 -0.1 -1.2 -0.4 -0.6 -0.1 0.7 0.8 1.2 1.0 0.3 -1.3 0.2 -1.6 -0.2
Hearing difficulty/problems with background noise 0.7 1.2 5.3 -0.4 -1.1 0.0 0.4 1.0 0.8 1.6 1.3 0.8 0.4 0.6 -0.1 1.9 -2.3 0.2
Hair/balding pattern: Pattern 2 1.1 1.4 4.8 0.7 1.4 1.0 1.9 -1.3 1.4 -0.2 1.2 2.2 0.6 1.2 -0.7 0.3 1.0 0.8
Had menopause 0.8 0.9 3.0 -0.1 -1.5 0.0 -0.6 1.0 -0.6 0.2 -1.7 -1.7 -1.4 -0.6 0.5 -0.5 -0.8 -1.0
Had other major operations 2.3 2.8 5.8 2.1 1.8 -1.0 1.4 -1.2 1.7 0.2 1.9 2.3 1.9 2.4 -1.4 1.1 0.2 2.3
Forced vital capacity (FVC) 0.7 2.7 10.8 -1.8 -2.0 -0.6 -1.3 -0.5 0.7 0.2 -1.5 -3.0 -0.1 -3.3 0.6 -0.2 -0.4 -2.7
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 4.8 0.5 -0.9 0.1 -1.1 -0.6 0.1 -0.7 -2.2 -1.7 -0.8 -1.5 -0.5 -1.0 -1.1 -2.0
Ever unenthusiastic/disinterested for a whole week 2.0 2.4 7.2 2.4 2.5 -0.5 1.0 1.2 -0.7 -0.8 2.2 2.7 -0.3 1.9 -0.9 -0.5 0.4 1.8
Qualifications: None of the above 0.5 1.1 4.7 -1.1 0.6 2.2 1.5 1.3 0.7 -0.3 1.5 1.3 0.7 0.3 -1.2 -0.1 -0.2 -0.2
Financial difficulties in last 2 years 1.3 1.8 7.8 1.1 2.3 -0.2 1.1 -0.4 0.0 -0.6 1.8 2.8 -0.0 2.1 -0.8 -0.2 0.5 1.2
Mouth/teeth dental problems 0.5 0.8 1.8 -0.2 0.6 1.4 1.0 0.2 1.3 0.4 0.9 0.6 1.3 -1.1 -0.6 0.3 0.8 -1.1
Heart attack 0.8 1.0 2.7 -0.2 1.6 -1.4 1.4 0.5 0.5 -1.6 0.7 1.2 0.4 0.5 -0.5 -1.3 0.8 0.1
Allergy 0.6 1.3 4.9 1.0 1.4 -0.3 1.4 0.1 0.2 -2.1 -0.5 -0.2 0.2 -0.8 -0.5 -2.2 1.9 -0.8
Pain all over the body in last month 0.6 0.6 2.6 -0.8 0.9 0.0 0.1 0.9 -0.9 -0.7 0.4 0.7 0.2 0.4 -1.4 -0.7 -1.6 0.6
Diabetes (self-reported) 1.4 2.2 5.6 0.6 1.9 -0.7 2.4 2.3 0.3 -1.4 1.4 1.8 0.9 2.2 0.1 -0.1 0.6 2.1
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 2.2 0.5 0.1 -0.8 -0.0 1.4 -0.5 1.5 0.9 0.3 -1.1 1.1 -0.1 1.2 -0.5 1.4
Medication: Ramipril 1.2 1.6 4.5 -0.9 0.0 1.5 -0.9 0.6 -0.8 2.1 1.4 1.4 0.2 1.6 -0.8 1.8 0.6 1.8
Medication: Simvastatin 0.3 0.4 1.2 -0.6 0.1 -1.0 -0.1 0.4 0.6 -0.9 0.1 -0.7 0.4 -0.5 1.1 -0.5 0.6 -0.4
Fluid intelligence score 0.8 1.6 6.7 2.6 0.2 -1.3 2.0 1.4 0.9 -0.3 -1.6 -1.8 -0.2 -0.6 1.4 0.7 0.7 0.3
Illnesses of siblings 0.9 1.3 8.8 -0.7 -0.6 -1.1 0.5 -0.4 0.8 -0.2 -1.8 -1.3 0.2 0.6 3.0 1.0 -0.0 1.2
Neuroticism score 0.5 1.0 3.4 -0.9 -1.8 -1.1 -1.1 0.5 0.2 1.2 -1.1 -0.9 -0.5 -1.3 -0.2 0.5 -0.9 -1.2
Weight 0.9 4.3 13.7 1.6 2.8 0.7 2.6 1.0 2.5 -0.7 3.0 3.7 2.4 0.7 -2.9 -0.6 1.3 0.2
Impedance of arm (right) 2.2 10.4 31.9 -0.7 -5.6 -0.3 -4.3 -0.8 -2.2 4.6 -3.6 -4.4 -3.8 -1.7 0.1 3.6 -3.9 -0.4
Arm fat percentage (right) 0.8 3.3 9.5 2.4 1.7 1.3 1.9 1.0 2.0 0.8 2.2 3.1 2.2 0.7 -3.0 0.8 0.1 0.7
Trunk fat-free mass 0.5 3.0 7.7 -0.3 2.6 0.3 2.2 1.3 2.2 -1.9 2.0 2.2 1.8 0.2 -1.0 -1.7 2.8 -0.3
Hip circumference 0.8 3.3 11.2 1.6 2.4 0.3 2.2 1.3 1.6 -0.6 2.5 3.3 1.9 0.8 -2.9 -0.7 0.6 0.4
Time employed in main current job 1.0 1.1 4.8 -2.2 -0.3 1.6 0.6 1.6 -0.0 -1.3 -0.4 -0.7 0.0 -0.5 1.7 -1.2 0.3 -0.3
Alcohol intake versus 10 years previously 0.9 1.3 4.7 -1.4 0.5 0.9 2.2 -0.5 1.9 -1.2 -0.0 -0.0 1.6 -0.7 0.2 -0.7 1.2 -1.0
Father’s age at death 0.3 0.4 2.0 0.8 -0.2 0.7 0.3 0.8 -0.9 0.0 -0.6 -1.0 -0.1 0.1 1.4 -0.1 -0.0 -0.1
Worrier / anxious feelings 0.5 0.9 3.0 0.3 -1.1 -1.4 -1.7 0.5 -1.4 0.8 -0.1 -0.4 -1.7 -0.1 -0.1 0.0 -1.3 0.1
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 6.7 -0.7 1.3 0.8 0.5 0.4 -0.1 0.8 1.9 2.6 0.1 1.9 -0.4 0.5 0.7 1.1
Falls in the last year 0.9 1.2 3.8 -0.5 1.1 -0.8 0.5 -0.5 1.0 0.7 1.1 1.9 1.0 1.8 -0.5 1.4 0.3 1.8
Hair/balding pattern: Pattern 3 0.6 0.8 3.2 -0.8 -1.1 -1.2 -1.3 -0.1 -0.7 -0.6 -0.8 -1.8 -0.5 -1.1 0.6 -0.7 -0.2 -0.6
Number of live births 1.2 1.6 6.3 0.6 -0.5 0.7 0.1 0.4 0.9 2.1 0.9 1.2 1.1 2.0 0.4 2.5 -0.5 1.9
Forced expiratory volume in 1-second (FEV1) 0.5 1.5 6.9 -1.4 -0.6 -0.9 -1.1 -0.8 0.7 -0.3 -0.9 -1.9 0.1 -2.6 0.4 -0.8 0.9 -2.1
Pulse rate 1.4 2.3 6.0 1.4 2.4 -1.6 1.4 -1.9 2.1 -1.1 1.5 1.7 1.6 -0.8 -0.9 -0.7 1.9 -0.1
Happiness 0.2 0.2 1.1 -0.4 -0.2 -0.6 -0.4 0.6 -0.1 0.6 -0.3 0.5 0.2 -0.3 -1.0 0.3 -0.0 0.2
Noisy workplace 1.1 1.3 3.4 1.1 0.9 0.8 0.9 -0.9 1.2 0.5 1.9 1.6 1.5 0.9 -1.5 1.2 -0.9 0.7
Qualifications: A levels/AS levels or equivalent 0.8 1.8 7.1 -0.6 -0.9 -0.8 -1.3 0.4 -2.0 -0.2 -1.4 -1.5 -2.7 1.3 1.4 0.1 -1.6 1.2
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.2 7.6 2.8 0.2 -1.5 0.5 0.5 0.5 0.7 -0.1 0.9 1.3 1.1 -0.8 1.2 -0.3 0.8
Mouth/teeth dental problems: Dentures 0.1 0.2 0.6 0.4 0.4 0.6 0.2 0.3 -0.0 -0.6 -0.2 0.4 -0.3 0.8 0.1 -0.2 0.8 0.5
Asthma 0.6 1.2 3.7 -1.5 -1.4 -0.6 -1.2 -0.6 -0.4 1.3 1.0 -0.7 1.2 -1.0 -0.7 0.8 -1.9 -0.9
Medication: Ibuprofen (e.g. Nurofen) 2.0 2.6 8.5 2.0 2.9 -0.9 1.4 0.3 0.1 0.0 2.2 2.6 1.1 1.3 0.1 0.1 2.5 1.7
Medication: Cholesterol lowering 0.5 0.8 2.3 -0.4 1.5 -1.3 -0.2 -0.8 0.6 -1.5 0.4 0.3 0.1 0.4 -0.5 -1.2 1.4 0.5
Depression (self-reported) 0.2 0.3 1.0 -0.1 -0.8 -0.0 -0.3 0.9 -0.9 0.4 -0.5 -0.1 -0.3 -0.1 -0.1 0.1 -1.0 0.0
Medication: Lansoprazole 0.5 0.6 2.1 0.3 -0.1 -0.4 -0.2 -1.3 1.4 0.2 0.3 0.8 1.4 0.6 0.8 1.0 -0.4 0.5
Prospective memory result 0.7 0.8 5.4 -2.3 0.2 0.3 -0.2 -0.2 -0.4 0.9 1.0 1.2 0.4 0.9 0.1 0.4 1.4 0.4
Lung cancer (father) 0.5 0.5 2.4 -1.5 -0.1 0.8 -0.5 -0.1 -0.2 -0.8 0.1 -0.4 -1.4 -0.2 -0.4 -1.1 -0.6 -0.5
Illnesses of mother 0.2 0.3 1.2 0.6 0.1 0.1 -0.0 0.3 -0.3 0.2 -0.5 -0.9 -1.1 -1.0 0.1 -0.0 0.7 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 4.9 -0.6 -0.7 -0.6 -0.6 -0.7 0.9 -0.1 -1.5 -2.2 -0.1 -2.2 0.8 -0.4 1.0 -1.6
Pulse wave Arterial Stiffness index 1.1 1.3 6.2 -0.4 -0.7 -0.8 -0.5 0.3 -0.9 -1.0 -0.3 -0.7 -1.3 -0.7 -1.8 -1.3 -2.5 -1.4
Impedance of arm (left) 2.2 10.2 32.0 -0.6 -5.7 -0.7 -4.0 -0.9 -1.6 4.4 -3.9 -4.8 -3.2 -2.2 0.7 3.6 -3.7 -0.6
Arm fat mass (right) 1.1 4.3 13.4 2.3 2.4 1.1 2.5 1.1 2.5 0.0 2.7 3.7 2.5 0.8 -3.1 0.2 0.9 0.7
Trunk predicted mass 0.5 3.1 7.6 -0.3 2.6 0.2 2.2 1.3 2.2 -1.9 2.1 2.2 1.8 0.2 -1.1 -1.6 2.8 -0.3
Standing height 0.2 1.6 5.2 -0.8 -2.0 -1.0 -1.0 -0.2 1.2 1.1 -1.6 -2.3 -1.2 -1.6 0.1 1.0 0.3 -1.3
Length of working week for main job 1.3 1.4 4.4 1.8 0.4 -0.1 1.2 2.1 1.2 -0.8 -1.3 -1.0 1.9 -1.0 1.4 0.0 0.8 -0.2
Exposure to tobacco smoke at home 0.3 0.3 2.1 0.5 -0.2 0.3 -0.1 0.3 0.4 0.4 -0.2 0.6 0.1 -0.8 -1.5 0.2 -0.2 -0.9
Breastfed as a baby 0.9 1.1 3.8 0.4 0.5 1.9 -0.6 -0.0 -1.2 -0.9 -1.3 -0.9 -0.5 0.3 1.2 -1.1 1.9 0.3
Tense / ‘highly strung’ 1.5 2.5 6.1 -1.6 -2.2 -0.9 -2.5 -1.1 -1.5 0.4 -0.5 -1.3 -1.9 -1.9 -1.2 -1.0 -1.9 -2.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 4.8 2.2 0.3 -0.9 0.1 0.6 -0.2 0.6 0.1 0.5 0.9 0.7 0.2 1.0 -1.0 1.0
Hair/balding pattern: Pattern 4 0.9 2.1 7.3 -0.3 -1.2 -2.7 -2.0 -1.5 -0.6 -0.1 -2.5 -2.5 -1.1 -0.7 1.2 -0.3 -0.3 -0.5
Birth weight of first child 0.8 1.4 3.2 1.4 1.4 -0.9 1.2 -1.0 1.1 0.1 1.1 1.6 1.4 1.8 1.5 1.0 0.4 0.9
Peak expiratory flow (PEF) 0.2 0.5 1.7 -0.8 0.3 -0.9 -0.4 -0.3 1.2 -0.1 0.3 -0.8 1.3 -1.2 0.0 -0.2 0.6 -0.7
Pulse wave reflection index 0.5 0.6 2.7 -1.0 -0.1 1.6 -0.7 0.8 -1.1 -0.6 -0.2 -0.3 -0.8 0.6 0.3 -0.6 -1.3 -0.4
Ever highly irritable/argumentative for 2 days 1.3 1.6 8.7 1.2 1.1 -2.9 0.9 1.0 -0.0 -0.8 1.1 1.4 -1.0 0.4 -2.1 -0.4 -1.0 0.4
Loud music exposure frequency 0.8 0.9 3.5 -0.1 -1.6 -0.6 0.5 1.9 0.9 1.2 -0.3 -0.3 -0.5 -0.7 -0.8 0.9 -1.0 -1.1
Qualifications: O levels/GCSEs or equivalent 0.9 1.4 4.0 0.5 -0.2 -1.5 -0.9 -0.5 -2.0 -1.8 -1.6 -1.6 -1.7 -0.1 0.9 -1.3 -0.5 -0.0
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.7 0.5 -0.4 -0.4 -0.7 0.4 -1.3 -0.1 -0.6 -0.3 -0.8 0.8 1.2 -0.4 -0.5 0.9
Blood clot in the leg (DVT) 0.6 0.8 3.4 -1.4 0.7 -0.2 -0.7 -0.3 -0.5 0.5 1.8 1.7 0.2 1.0 -0.7 -0.0 0.6 0.6
Medication: Paracetamol 0.7 1.1 3.9 0.3 1.9 -1.6 1.1 0.5 0.0 -0.7 1.1 2.0 0.5 1.5 -0.1 -0.2 0.1 1.0
Headache pain in last month 0.8 1.4 5.3 0.9 0.2 0.6 1.1 -0.2 1.0 2.3 0.6 1.5 1.9 0.1 0.3 2.3 0.4 0.7
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 5.0 -0.8 -2.2 1.8 -0.3 1.0 -0.3 1.1 -1.8 -1.4 -0.4 -0.4 1.3 0.9 -1.8 -1.3
Glaucoma (self-reported) 1.1 1.3 5.6 0.7 -0.1 -1.4 -0.6 -1.1 0.8 1.3 1.5 0.7 0.9 -0.2 -2.4 1.2 -1.7 0.1
Gout (self-reported) 0.4 0.5 2.6 0.1 0.1 -0.3 -0.5 0.4 -0.7 -0.8 -0.1 -0.3 -1.3 -0.6 -1.6 -0.8 -0.5 -0.4
Hypothyroidism/myxoedema (self-reported) 0.5 1.1 6.0 -1.1 -0.5 1.6 0.3 0.6 0.2 0.2 -0.2 0.5 -0.6 1.6 -0.3 0.9 -2.4 1.1
Medication: Amlodipine 0.5 0.7 3.7 0.2 0.6 -0.8 0.2 -1.7 0.6 0.4 1.0 0.5 0.5 -0.5 -1.9 0.1 -0.4 -0.1
Medication: Ventolin 100micrograms inhaler 0.5 0.7 2.7 0.0 0.5 0.3 0.4 1.2 -0.2 0.9 1.6 1.1 -0.6 0.6 -0.7 0.7 -0.8 1.2
Birth weight 0.6 1.2 4.1 0.1 1.6 2.0 1.3 1.7 0.7 -0.5 1.0 1.5 -0.2 0.8 -0.0 -0.0 1.4 0.7
Chronic bronchitis/emphysema (mother) 0.7 0.8 3.3 -1.4 -0.6 -1.8 -1.4 -0.9 -0.3 -0.6 -0.8 -1.2 -0.0 -0.5 0.5 -0.4 -1.1 -0.3
High blood pressure (siblings) 1.5 2.2 9.1 1.1 2.2 0.2 0.9 0.7 -0.5 -0.4 2.9 3.0 0.7 1.0 -1.6 -0.8 1.4 0.6
Forced vital capacity (FVC), Best measure 0.5 1.9 8.1 -1.3 -1.9 -0.6 -0.7 -0.4 1.1 0.6 -1.7 -2.8 -0.3 -2.3 0.9 0.4 -0.2 -1.7
Body fat percentage 0.6 2.3 9.7 2.5 1.1 1.1 1.4 0.3 1.6 0.5 1.4 2.1 1.9 -0.2 -3.1 0.3 -0.4 -0.1
Leg fat percentage (right) 0.8 2.8 7.5 1.8 2.4 1.3 1.7 0.3 1.2 -1.0 2.0 2.6 2.4 0.1 -2.7 -1.3 0.8 -0.2
Arm fat-free mass (right) 0.7 3.7 8.8 0.1 3.0 0.6 2.4 0.7 2.5 -2.1 2.2 2.7 2.3 0.2 -1.1 -1.8 2.7 -0.3
Exposure to tobacco smoke outside home 1.1 1.4 5.4 0.4 0.8 1.5 1.0 1.0 1.9 1.1 0.8 2.3 1.6 0.9 -0.5 1.4 0.3 0.3
Comparative body size at age 10 1.3 3.7 15.8 2.5 4.0 0.4 1.9 0.4 -0.4 -2.7 1.2 2.5 1.3 0.5 -1.0 -2.7 2.1 0.4
Number of full brothers 1.0 1.3 6.1 -0.8 0.3 2.5 0.4 1.4 -0.7 0.7 2.3 1.3 1.3 0.5 -0.1 0.3 -0.6 -0.3
Worry too long after embarrassment 0.7 1.1 3.6 -0.1 -1.9 -0.5 -1.0 0.5 -0.4 1.4 -0.7 -1.3 0.1 -1.6 -0.4 0.6 -1.6 -1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 2.8 3.7 8.6 -0.0 -2.1 -1.6 -2.2 -0.2 -0.7 -0.9 -2.5 -2.9 -1.7 -2.3 -1.3 -1.9 -2.2 -2.9
Wheeze or whistling in the chest in last year 1.3 2.4 7.8 -0.1 1.1 -0.7 1.3 0.1 1.7 1.0 2.6 2.8 1.2 2.1 -0.4 2.0 -1.1 1.7
Number of children fathered 1.5 1.7 4.5 -1.4 0.2 0.5 0.3 0.4 0.1 2.0 2.1 1.9 0.6 1.8 0.1 2.1 0.3 1.6
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 4.7 -0.2 0.0 0.3 -1.7 -0.5 -2.2 0.6 1.1 0.7 -0.5 0.3 -1.0 -0.5 -0.2 -0.2
Age at first live birth 0.7 1.3 5.2 0.6 -0.5 0.2 0.6 0.4 0.5 -1.1 -1.3 -1.9 0.7 -1.4 2.3 -0.7 -0.4 -1.6
Pulse wave peak to peak time 0.9 1.0 5.3 0.4 0.5 0.9 0.4 -0.3 0.8 1.0 0.2 0.6 1.0 0.6 1.5 1.2 2.3 1.2
Health satisfaction 0.9 1.2 4.6 0.4 -0.9 -0.7 -0.8 -0.0 0.9 2.0 0.8 1.4 0.6 0.3 -2.1 1.2 -1.4 0.1
Shortness of breath walking on level ground 0.5 0.6 1.8 -0.2 0.6 0.4 -0.5 0.5 -1.2 -0.2 1.3 0.9 -0.6 1.0 -0.9 -0.1 -1.2 0.4
Qualifications: College or University degree 0.7 2.1 8.6 -0.2 -1.5 -1.2 -1.6 -1.2 -1.0 0.2 -2.1 -2.9 -1.4 -0.4 2.4 0.4 -1.2 0.0
Eye problems/disorders: None of the above 0.3 0.4 1.4 -0.1 -0.4 0.6 0.1 0.3 -0.7 1.2 0.1 0.2 -0.5 1.0 0.1 0.9 0.3 0.7
Mouth/teeth dental problems: Loose teeth 0.6 0.7 3.0 -0.2 0.4 0.1 0.9 -0.1 1.1 -0.7 -0.5 -0.0 1.6 -0.8 0.4 -0.3 1.7 -1.1
Emphysema/chronic bronchitis 0.5 0.6 2.2 -1.1 -0.8 0.4 -0.8 -0.4 -0.1 1.5 -0.7 -0.4 0.5 0.0 1.1 1.0 0.5 -0.4
Medication for pain relief, constipation, heartburn 1.7 3.0 10.1 -2.0 -3.2 1.4 -2.2 -0.9 -1.2 0.4 -1.6 -2.6 -0.9 -1.9 0.1 -0.4 -2.1 -1.7
Neck or shoulder pain in last month 0.3 0.5 1.9 0.6 0.7 -0.5 0.0 -1.4 0.1 0.1 -0.1 0.5 0.9 -0.2 1.3 -0.2 1.2 -0.2
Medication: Blood pressure 1.1 1.9 8.2 0.7 2.9 -0.7 0.8 -0.5 -0.1 -1.2 2.0 1.6 0.1 0.6 -1.2 -1.0 1.9 1.9
Angina (self-reported) 1.0 1.3 4.1 0.1 1.6 0.8 1.8 1.4 0.8 -0.5 1.0 2.0 1.0 1.0 0.2 -0.2 1.6 0.8
Migraine (self-reported) 0.6 0.7 3.2 -0.1 1.4 -0.7 -0.3 -1.8 -1.1 -1.0 -0.4 0.1 0.9 0.7 0.8 -0.4 0.5 0.7
Medication: Ibuprofen 2.1 2.5 10.4 1.4 3.2 -0.7 1.3 1.1 -0.9 -1.0 1.7 2.3 0.2 0.8 -0.3 -1.5 2.7 1.1
Medication: Allopurinol 0.5 0.7 4.3 -0.7 -0.3 -0.7 -1.3 -0.1 -0.2 -0.5 -0.3 -0.9 -2.1 -0.4 -1.0 -0.5 -0.5 0.1
Medication: Omeprazole 1.5 1.8 5.6 0.7 1.0 -0.6 1.0 -1.4 2.3 0.6 1.3 2.0 2.4 1.3 -0.6 1.3 0.2 1.0
Medication: Seretide 50 evohaler 0.9 1.1 3.2 0.8 1.1 0.1 1.7 1.8 0.5 -1.1 -1.4 -0.7 -0.1 -0.0 1.1 -0.4 1.7 0.6
Mean time to correctly identify matches 1.1 2.1 5.8 2.1 -0.8 0.7 0.1 1.3 -0.5 -0.2 -1.3 -1.5 -0.3 -2.4 -2.1 -1.2 -2.0 -2.2
Heart disease (mother) 0.6 0.7 2.9 -0.4 0.7 0.2 1.2 0.0 1.6 -0.3 0.5 1.2 1.7 0.7 -0.2 0.5 -0.1 0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 0.9 3.0 0.6 1.5 1.7 0.3 1.0 -0.9 -1.3 0.5 0.9 1.0 0.7 1.0 -1.1 0.2 0.0
Whole body fat mass 0.8 3.3 9.5 2.3 1.8 1.1 2.3 0.9 2.5 0.2 2.1 2.8 2.4 -0.1 -3.1 0.1 0.6 -0.1
Leg fat mass (right) 1.0 3.8 10.2 2.1 2.5 1.4 2.3 0.6 2.1 -0.7 2.5 3.2 2.5 0.2 -2.9 -0.9 1.1 -0.1
Arm predicted mass (right) 0.8 4.2 10.2 0.2 3.2 0.9 2.6 0.6 2.5 -2.2 2.5 3.0 2.3 0.4 -1.1 -1.9 3.0 -0.2
Pulse rate, automated reading 0.5 1.5 4.5 0.6 1.7 0.5 2.1 0.2 1.4 -0.7 1.5 0.9 2.1 -1.0 -0.6 -0.5 1.5 -0.8
Alcohol intake frequency. 1.0 2.3 10.1 1.5 3.2 -1.1 1.1 -0.3 -0.7 -2.6 0.8 1.8 1.0 0.1 -1.3 -2.2 0.6 0.2
Comparative height size at age 10 0.2 1.3 4.2 0.9 0.5 -0.9 0.2 -1.0 1.8 -1.6 -1.3 -0.9 0.4 -1.6 -0.3 -1.1 0.8 -2.0
Number of full sisters 0.8 0.9 2.7 -1.5 0.8 0.6 1.0 0.3 -0.3 0.3 1.6 1.6 0.2 1.4 -0.9 0.5 -0.2 1.1
Suffer from ‘nerves’ 1.7 2.7 10.4 -1.8 -3.2 -0.8 -1.0 -0.5 0.9 1.7 -2.1 -2.0 -0.9 -1.1 -1.0 1.3 -2.4 -1.4
Overall health rating 0.7 1.5 8.0 0.7 1.6 0.6 0.4 -0.7 0.8 -0.2 2.2 2.8 1.2 0.4 -1.6 -0.7 0.9 0.1
Chest pain or discomfort 2.1 3.0 9.4 0.7 2.6 -1.1 2.3 3.1 0.0 -0.9 2.4 2.6 1.5 0.9 -2.2 -0.9 0.3 0.1
Had major operations 0.3 0.4 2.0 -0.5 0.5 1.4 0.9 0.7 0.7 -0.8 -0.2 0.4 0.6 -0.3 -0.3 -0.4 0.1 -0.5
Age at last live birth 0.3 0.4 2.3 -0.1 -0.1 1.5 0.1 -0.4 0.5 -0.7 0.1 -0.2 0.5 -0.2 1.5 -0.4 0.2 -0.7
Family relationship satisfaction 0.5 0.6 1.3 1.0 -0.2 1.0 0.6 1.1 0.4 0.5 0.2 1.1 -0.6 1.1 -0.0 0.2 0.4 1.1
Leg pain on walking 0.5 0.6 2.8 1.7 0.6 -0.3 0.9 0.2 1.5 -0.2 0.4 0.9 1.2 0.3 0.1 0.4 0.6 -0.1
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.4 6.3 -0.6 0.9 1.3 0.8 -1.3 1.1 0.5 1.6 2.0 1.0 0.5 -2.5 0.6 0.1 -0.1
Commuting to job workplace: Car/motor vehicle 1.3 1.5 6.4 -0.5 0.9 2.5 -1.0 -0.5 -2.0 -0.8 2.1 0.6 0.2 -0.2 -0.8 -1.7 -0.7 -0.7
Illness, injury, bereavement, stress in last 2 years 2.7 3.3 10.8 -1.5 -1.7 0.3 -0.9 0.1 -0.8 -0.9 -2.7 -3.3 -1.8 -3.0 1.2 -1.8 0.6 -2.6
Medication: Aspirin 1.2 1.5 4.6 1.1 2.0 0.7 0.7 2.1 -0.7 -0.7 0.6 1.5 -0.7 1.8 -1.2 -0.5 0.6 1.7
Supplements: Vitamin C 1.3 1.5 6.3 -0.1 0.4 1.4 0.3 1.2 1.0 0.5 1.0 2.5 0.2 2.2 -1.6 0.9 -0.9 1.4
Knee pain experienced in last month 1.1 1.6 5.3 1.2 2.1 -0.4 0.6 -0.2 -0.3 -1.7 2.3 1.7 0.5 -0.1 -0.9 -2.1 0.7 -1.0
Hypertension (Self-reported) 1.3 3.5 14.3 1.0 3.8 -0.3 1.2 0.1 -0.5 -2.4 2.5 3.2 0.9 1.2 -1.6 -2.2 1.6 0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.3 1.5 7.6 1.2 -0.4 -0.4 0.8 -1.3 2.8 0.9 -0.8 -0.4 1.9 -1.3 0.8 1.5 0.4 -0.9
Illnesses of father: Heart disease 0.5 0.7 2.6 1.6 1.1 -0.5 1.4 0.9 0.5 -0.7 0.8 0.8 1.2 -0.1 -0.5 -0.3 0.8 -0.1
Illnesses of siblings: Diabetes 0.8 1.0 5.4 -0.1 -0.5 1.0 0.6 1.7 0.0 -0.0 -0.3 -0.6 0.5 -1.6 -0.6 -1.1 0.6 -2.3
Smoking status: Previous 0.2 0.3 1.4 -0.3 -0.6 0.2 -0.3 1.1 -0.8 -0.0 -0.6 -1.2 -0.2 -0.2 0.3 -0.0 0.2 0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 2.2 -0.5 0.7 0.9 0.6 -0.7 1.5 1.0 0.9 0.6 0.9 0.3 0.2 1.4 0.3 1.1
Whole body fat-free mass 0.6 3.7 8.9 0.3 2.9 0.5 2.5 1.3 2.5 -1.6 2.6 3.0 1.9 0.6 -1.5 -1.3 2.5 0.1
Leg fat-free mass (right) 0.8 4.2 13.8 1.1 2.8 0.5 2.8 1.3 3.1 -0.8 2.9 3.7 2.2 1.2 -1.6 -0.2 1.7 0.7
Arm fat percentage (left) 0.9 3.4 9.9 2.5 1.9 1.2 2.1 0.8 2.2 0.6 2.2 3.1 2.5 0.6 -2.8 0.7 0.3 0.7
Average weekly red wine intake 0.9 1.4 4.3 -2.1 -0.9 -1.0 -1.7 -0.3 -1.0 0.6 -0.5 -0.8 -1.1 1.6 1.4 1.2 -0.6 1.5
Handedness (chirality/laterality): Left-handed 0.9 1.0 2.4 -1.2 -1.4 -1.2 -1.6 -0.6 -1.1 1.2 -1.3 -0.6 -1.3 0.4 -0.6 0.4 -0.4 0.4
Mood swings 0.7 1.2 4.6 -0.8 0.7 0.2 0.7 1.2 0.4 -1.4 -0.9 0.3 1.0 -0.9 1.2 -1.6 2.1 -1.3
Loneliness, isolation 0.6 0.8 2.0 0.2 -0.4 -0.8 -0.5 1.2 0.3 -1.1 -1.1 -0.8 -0.4 -0.8 -0.9 -1.4 -1.3 -1.2
Long-standing illness, disability or infirmity 2.3 3.6 10.2 1.8 3.2 -0.4 2.8 1.0 1.3 -1.9 2.1 2.8 1.6 2.5 -0.0 -0.1 0.7 2.1
Ever had bowel cancer screening 1.0 1.2 4.3 0.1 2.1 0.3 1.0 -0.5 0.1 -1.5 1.7 1.6 0.9 1.5 1.0 -0.9 -0.2 0.2
Diabetes diagnosed by doctor 1.4 2.2 7.1 1.0 1.4 -0.6 2.7 2.1 1.2 -0.7 1.3 1.8 1.6 2.2 -0.1 0.7 0.2 2.0
Ever had stillbirth, spontaneous miscarriage or termination 3.2 3.4 10.9 1.4 3.3 -1.3 2.2 -1.1 2.5 -2.3 1.4 2.1 2.0 0.7 0.6 -0.9 2.7 0.5
Friendships satisfaction 0.5 0.6 2.1 1.4 -0.6 0.0 0.7 -0.2 0.5 1.5 -0.4 0.5 -0.1 0.2 -0.1 1.4 0.4 0.7
Qualifications: nursing, teaching 0.9 1.5 4.5 -0.3 -0.9 -1.8 -0.6 0.3 -0.7 1.5 0.1 -0.2 -1.1 2.1 0.0 1.7 -1.7 1.8
Commuting to job workplace: Walk 1.6 1.8 4.9 -0.7 -1.6 -2.2 -0.5 2.1 -0.8 1.7 -0.9 -0.5 -1.9 0.9 -0.5 1.3 -1.6 0.8
Eye problems/disorders: Cataract 0.8 0.9 3.3 -0.5 0.6 -1.8 -0.8 -0.5 -1.4 -1.6 -0.0 -0.4 -0.3 -0.2 0.9 -1.8 0.0 -0.6
Mouth/teeth dental problems: Mouth ulcers 1.0 1.5 5.9 1.4 0.2 -1.5 0.2 0.5 -1.0 0.5 1.0 1.0 -1.0 2.4 -0.4 1.0 -0.9 2.4
Medication for cholesterol 1.2 1.9 6.2 0.7 -2.5 0.7 -0.1 0.8 0.7 1.8 -1.8 -2.4 -0.8 -1.7 0.1 1.5 -1.0 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.9 -0.2 1.0 -1.4 0.2 0.1 -0.2 -1.0 1.0 0.6 0.6 -0.9 0.4 -1.4 1.0 -1.0
Back pain experienced in last month 0.5 0.8 4.0 0.8 0.2 -0.3 1.4 -0.4 2.0 -0.2 -0.6 0.0 1.9 0.0 0.4 0.5 0.8 -0.3
Mineral and other dietary supplements 0.6 0.8 5.7 -0.2 0.5 0.9 1.8 2.4 -0.4 -0.6 -0.3 -0.1 0.1 -0.2 1.0 -0.3 0.7 0.3
Breast cancer (self-reported) 0.7 0.8 3.3 -0.3 -1.3 -0.5 -1.8 -0.6 -1.3 0.6 0.5 -0.7 -1.0 -0.8 -0.7 -0.5 -0.5 -0.8
Asthma (self-reported) 0.5 1.0 3.8 -1.0 -1.0 -0.2 -1.3 -0.8 -0.6 1.4 1.4 -0.2 0.9 -0.5 -0.8 1.0 -1.9 -0.4
Osteoporosis (self-reported) 0.9 1.1 2.5 -0.6 -1.2 1.6 -0.8 0.1 -0.8 0.4 -1.0 -1.3 -1.4 -1.2 -0.5 -0.8 -1.2 -1.6
Osteoarthritis (self-reported) 0.7 1.0 2.6 0.1 1.5 -0.1 0.1 -0.2 -0.9 -1.5 1.6 1.3 0.5 0.4 -1.4 -1.4 -0.5 0.0
Medication: Aspirin 0.9 1.2 3.7 0.9 1.7 0.4 0.7 1.9 -0.3 -0.6 0.4 1.4 -0.7 1.7 -1.0 -0.1 0.6 1.7
Medication: Gliclazide 0.4 0.4 1.8 1.4 -0.4 0.1 0.1 0.2 0.0 0.5 0.7 1.0 -0.2 1.0 -0.9 0.3 -0.8 0.4
Illnesses of father: None of the above (group 1) 1.4 1.7 6.2 0.1 -2.2 -0.1 -0.4 -0.5 0.7 2.2 -0.8 -1.1 -0.8 -0.5 -0.9 2.1 -2.5 -0.2
Smoking status: Current 0.3 0.5 2.3 -1.5 -1.2 -0.2 -0.0 -0.0 0.4 0.4 -0.8 0.1 0.4 0.7 0.3 0.8 -1.4 0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.3 3.4 -0.9 0.4 -1.7 0.2 0.0 0.2 -1.5 -1.3 -1.8 0.1 -1.6 1.2 -1.4 1.1 -1.2
Whole body water mass 0.7 3.8 9.6 0.5 2.9 0.3 2.5 1.3 2.6 -1.5 2.6 3.1 2.0 0.7 -1.6 -1.2 2.5 0.1
Leg predicted mass (right) 0.8 4.3 13.7 1.2 2.9 0.4 2.8 1.2 3.0 -0.9 2.9 3.7 2.2 1.1 -1.6 -0.3 1.8 0.7
Arm fat mass (left) 1.0 4.3 12.1 2.2 2.5 1.1 2.6 1.1 2.6 -0.1 2.6 3.5 3.0 0.5 -2.8 -0.1 1.1 0.4
Number of self-reported non-cancer illnesses 2.0 3.4 12.2 1.0 3.5 -0.3 0.1 -0.5 -0.6 -1.7 3.5 3.1 0.6 2.3 -1.4 -1.1 -0.3 1.9
Average weekly champagne plus white wine intake 0.6 0.8 3.8 0.8 0.1 -1.0 0.3 -1.3 0.7 0.5 -1.0 -0.1 -0.4 0.6 1.9 1.0 1.0 0.8
Miserableness 0.4 0.7 4.1 0.2 0.2 0.9 0.1 0.4 0.0 0.4 -0.7 0.2 1.6 0.5 2.0 0.5 1.4 0.3
Guilty feelings 0.7 1.0 3.2 1.0 -0.9 -1.6 0.6 0.8 0.5 1.0 -0.3 -0.0 -0.4 -0.8 -1.6 0.4 -1.8 -1.2
Wears glasses or contact lenses 0.5 0.5 1.8 -0.4 -1.1 -1.4 -0.5 -0.3 0.1 0.8 -0.3 -0.6 -0.8 0.8 0.9 1.0 0.1 0.6
Ever taken oral contraceptive pill 0.9 1.0 6.3 0.5 0.2 -2.5 0.2 0.3 0.2 1.5 1.7 0.8 0.2 -0.2 -0.9 0.9 -0.2 -0.4
Hearing aid user 1.9 2.1 10.9 0.8 2.0 0.9 3.3 1.9 1.3 -0.8 0.5 1.4 1.3 1.6 0.1 0.6 0.8 1.4
Mother’s age at death 0.8 1.1 4.2 0.3 1.2 -0.3 -0.0 -0.6 -1.0 -0.2 1.9 1.1 0.1 2.1 0.3 -0.0 -0.1 1.9
Financial situation satisfaction 1.1 1.3 5.3 -0.5 -2.3 -0.2 -0.3 -0.4 1.2 1.4 -1.9 -1.5 0.7 -1.5 -0.2 1.3 -0.6 -0.4
Tinnitus: Yes, now most or all of the time 1.2 1.4 6.5 0.5 1.7 -2.2 1.3 -0.6 0.9 -1.1 1.1 0.6 2.5 -0.3 0.0 -0.3 0.2 -0.0
Commuting to job workplace: Public transport 1.2 1.5 7.6 0.8 -0.3 -2.7 0.8 -0.8 1.9 0.5 -1.3 -1.4 0.5 -1.6 -0.2 1.0 1.1 -0.5
Eye problems/disorders: Glaucoma 1.4 1.7 5.2 0.8 -1.1 -2.3 -0.7 -0.7 1.3 1.4 1.3 -0.1 1.4 -1.2 -2.1 1.2 -1.2 -1.1
Medication: Blood pressure 0.9 1.7 6.4 -0.8 2.0 -0.6 0.2 0.4 -1.7 -0.9 2.2 2.5 0.5 1.6 -1.1 -1.1 0.2 0.8
Pain type(s) experienced in last month: Hip pain 2.0 2.6 7.3 0.8 2.7 0.3 1.0 -0.5 0.8 -2.4 2.6 2.4 1.5 1.3 0.1 -1.8 1.6 -0.0
Supplements: Fish oil (including cod liver oil) 0.5 0.7 4.1 0.3 -0.5 -1.1 -0.9 -2.0 1.2 0.5 0.1 0.2 0.5 0.6 -0.5 0.9 -0.8 0.1
High cholesterol (Self-reported) 0.2 0.3 1.2 -0.4 0.1 -0.4 0.2 0.3 0.6 -0.5 -0.0 0.3 1.1 -0.4 0.5 -0.5 0.8 -0.8
Medication: Bendroflumethiazide 0.8 1.2 5.6 2.4 0.7 0.4 0.1 0.3 -0.5 1.0 0.7 1.8 -0.6 1.5 -0.5 0.9 -0.2 1.5
Medication: Paracetamol 0.8 1.2 3.9 -0.3 2.0 -1.0 1.6 1.6 0.1 -1.7 0.4 1.2 0.1 0.8 0.3 -1.2 0.6 0.7
Medication: Lisinopril 3.0 3.9 14.7 0.7 3.8 -1.7 2.8 0.8 1.0 -1.7 2.3 3.2 1.6 1.6 -0.6 -1.1 2.1 1.4
Medication: Atorvastatin 0.8 1.0 5.3 1.2 1.2 -0.2 1.2 2.3 -0.4 -0.3 -0.4 1.2 -0.7 1.0 -1.0 -0.2 0.4 1.3
Illnesses of father: High blood pressure 1.4 1.8 7.4 -0.1 2.7 -0.5 -0.6 -0.4 -1.9 -1.5 1.3 1.7 0.1 1.0 0.2 -1.8 1.6 1.0
Alcohol drinker status: Never 1.4 1.6 5.1 -0.2 2.0 -1.9 0.1 -0.8 -0.6 -0.2 2.3 1.9 0.3 1.5 -0.9 -0.1 -0.1 1.9
Ever smoked 0.4 0.7 2.6 0.0 -1.4 0.8 0.5 1.6 0.7 0.8 -0.6 -0.4 -0.4 0.7 0.1 1.2 -0.7 0.6
Basal metabolic rate 0.7 3.8 9.6 0.6 2.8 0.7 2.5 1.2 2.7 -1.4 2.5 3.1 2.1 0.5 -1.9 -1.1 2.2 0.0
Leg fat percentage (left) 0.8 2.8 7.5 1.7 2.4 1.4 2.0 0.2 1.6 -1.4 1.6 2.3 2.7 -0.1 -2.3 -1.4 0.8 -0.4
Arm fat-free mass (left) 0.9 4.6 11.3 0.3 3.4 0.6 2.8 1.2 2.5 -2.4 2.5 3.1 2.3 0.2 -1.8 -2.2 2.7 -0.4
Number of operations (self-reported) 1.9 2.8 8.2 1.0 2.5 0.3 2.4 -0.0 2.2 -0.9 1.4 2.4 2.9 1.9 -0.3 0.5 0.4 1.7
Average weekly beer plus cider intake 0.1 0.2 0.8 -0.5 -0.3 0.7 0.2 -0.0 0.6 -0.3 0.9 0.4 -0.2 -0.2 -0.1 -0.3 -0.4 -0.5
Irritability 0.3 0.5 2.8 -0.5 0.7 -0.4 0.2 -1.1 0.9 -0.2 0.1 -0.0 0.6 -0.8 1.0 -0.1 1.7 -0.2
Risk taking 2.3 3.4 11.4 2.2 3.0 -0.8 0.4 -2.1 -0.1 -0.9 2.4 3.4 1.1 2.8 0.1 -0.6 1.3 1.5
Ever had prostate specific antigen (PSA) test 1.1 1.2 3.4 -1.1 0.2 -0.9 -0.5 -1.8 0.1 1.2 1.8 1.5 -0.3 1.4 -0.3 1.3 -0.6 1.3
Fractured/broken bones in last 5 years 1.1 1.4 3.5 0.5 -0.1 -0.4 -1.6 -0.7 -1.3 1.4 0.6 0.8 -1.9 1.6 -1.7 0.6 -1.1 1.2
Age started oral contraceptive pill 0.3 0.4 1.5 -0.0 -0.2 -0.2 -0.3 0.9 -1.1 -0.7 0.2 -0.6 -1.2 0.1 -0.0 -0.9 -0.6 0.0
Diastolic blood pressure, automated reading 0.8 2.3 5.8 -0.5 1.5 2.3 1.3 0.8 0.9 -1.6 2.0 1.1 1.3 -1.4 -0.7 -2.4 1.6 -2.0
Ever depressed for a whole week 0.5 0.6 5.0 2.2 -0.0 -1.1 -0.2 -0.6 0.4 0.6 -0.0 0.6 -0.2 0.3 -0.8 0.7 -0.2 0.2
Unable to work because of sickness or disability 0.6 0.8 3.4 -1.2 0.5 -0.4 1.3 1.1 1.7 -0.2 -0.1 0.6 1.8 -0.1 -0.1 0.7 -0.0 0.3
Commuting to job workplace: Cycle 1.3 1.5 5.5 0.0 -0.0 -0.5 1.5 -0.3 2.0 0.8 -1.3 0.1 1.7 1.4 1.1 2.3 -0.0 1.6
Myopia 1.2 1.8 4.5 -1.0 -2.0 -1.6 -2.1 -1.7 -1.4 1.0 -0.6 -2.0 -0.9 -0.9 0.3 0.7 -1.4 -0.2
Vascular/heart problems diagnosed by doctor 1.6 4.3 14.7 -1.6 -3.8 0.2 -1.6 -0.3 0.2 1.6 -3.4 -3.8 -1.3 -1.7 1.9 1.7 -1.7 -1.4
Cholesterol lowering medication 0.5 0.7 2.9 -0.9 -0.5 0.8 -0.1 1.7 0.0 0.8 0.5 0.4 1.0 0.3 1.6 0.7 0.3 -0.0
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 4.1 0.4 0.3 -0.5 0.6 -1.4 2.0 0.6 0.6 1.1 1.8 0.4 -0.3 1.0 0.2 0.1
Pain experienced in last month 0.9 1.5 5.8 -0.9 -1.9 -0.4 -1.3 -0.2 -1.1 0.7 -0.9 -1.3 -2.4 0.9 0.3 1.0 -1.6 1.1
Supplements: Calcium 1.0 1.1 5.9 -0.1 -1.2 0.7 -2.4 -0.9 -1.4 0.3 -0.4 -0.7 -2.0 0.5 -0.6 -0.4 -1.0 -0.2
Basal cell carcinoma (self-reported) 0.6 0.8 3.5 0.4 0.1 -0.1 1.5 0.2 1.6 0.0 -0.6 -0.1 1.9 0.9 0.7 0.9 -0.3 0.4
Heart attack/myocardial infarction (self-reported) 0.8 1.1 2.9 -0.4 1.7 -1.1 1.6 0.6 0.7 -1.5 0.7 1.4 0.9 0.5 -0.2 -1.1 1.0 0.2
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 3.3 -1.6 0.6 -0.5 -0.6 -0.1 -0.4 0.4 1.8 1.6 0.2 0.9 -0.6 -0.1 0.7 0.4
Heart disease (siblings) 1.3 1.6 5.6 1.6 1.2 1.5 -0.1 -0.3 -0.4 0.3 2.4 2.1 -0.4 1.3 -2.0 0.4 -0.6 1.3
Alcohol drinker status: Previous 1.0 1.1 4.9 -0.1 -1.1 1.3 -1.7 0.1 -2.2 0.6 -0.9 -0.1 -1.7 0.4 -0.2 0.1 -1.3 0.2
Pack years of smoking 1.1 1.6 6.2 0.1 0.7 1.4 -1.1 -1.2 -2.1 -0.6 0.5 1.5 -1.3 2.5 -1.4 -0.8 -0.1 1.4
Impedance of whole body 2.1 10.9 33.4 -1.2 -5.6 -0.4 -4.2 -1.8 -1.8 3.2 -4.8 -5.8 -3.0 -3.1 1.1 2.4 -3.4 -1.7
Leg fat mass (left) 1.0 3.8 10.0 2.2 2.6 1.3 2.4 0.4 2.2 -1.0 2.4 3.2 2.6 0.1 -2.8 -1.0 1.1 -0.2
Arm predicted mass (left) 1.0 4.9 11.8 0.5 3.4 0.8 3.0 1.3 2.6 -2.0 2.8 3.4 2.5 0.6 -1.9 -1.8 2.6 -0.1