[Hub]/) : Traits : BMI :

chr4:119,605,671-121,242,474

Best TWAS P=2.41e-08 · Best GWAS P=9.35e-08 conditioned to 0.146

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia PDE5A 0.13 0.02 enet 12 0.06 6.4e-03 5.0 -5.1 3.0e-07 -0.58 0.09 0.72 FALSE
2 GTEx Brain Caudate basal ganglia RP11-33B1.4 0.12 0.16 lasso 4 0.15 5.7e-05 5.0 -5.3 1.5e-07 -0.68 0.08 0.86 FALSE
3 GTEx Cells Transformed fibroblasts RP11-33B1.1 0.23 0.44 lasso 11 0.45 1.8e-37 5.1 -5.1 2.7e-07 -0.72 0.10 0.89 FALSE
4 GTEx Liver RP11-33B1.1 0.18 0.12 enet 31 0.17 1.6e-05 5.0 -5.2 1.7e-07 -0.63 0.11 0.88 FALSE
5 GTEx Liver RP11-33B1.4 0.18 0.14 lasso 6 0.12 3.2e-04 5.2 -5.2 2.4e-07 -0.70 0.07 0.90 FALSE
6 GTEx Pancreas RP11-33B1.4 0.20 0.05 lasso 16 0.05 3.8e-03 5.2 -5.5 3.8e-08 -0.69 0.05 0.93 FALSE
7 GTEx Testis RP11-33B1.4 0.23 0.31 enet 16 0.37 1.5e-17 5.0 -5.6 2.4e-08 -0.80 0.07 0.93 TRUE
8 GTEx Thyroid RP11-33B1.4 0.07 0.07 lasso 3 0.05 1.8e-04 5.2 -5.3 1.1e-07 -0.69 0.05 0.93 FALSE
9 GTEx Whole Blood C4orf3 0.11 0.16 lasso 6 0.16 3.0e-14 5.0 5.1 2.9e-07 0.67 0.11 0.89 FALSE
10 NTR Blood PDE5A 0.03 0.05 lasso 6 0.04 2.0e-13 5.0 -5.5 3.6e-08 -0.69 0.11 0.88 FALSE