Best TWAS P=1.63e-09 · Best GWAS P=6.41e-29 conditioned to 2.43e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | MED20 | 0.11 | 0.05 | lasso | 4 | 0.08 | 9.4e-07 | -5.4 | 5.6 | 2.0e-08 | 0.01 | 0.20 | 0.78 | TRUE |
| 2 | GTEx | Testis | NFYA | 0.21 | 0.16 | enet | 9 | 0.10 | 4.3e-05 | 5.1 | 5.3 | 1.4e-07 | 0.04 | 0.07 | 0.93 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PRPH2 | 0.07 | 0.03 | enet | 6 | 0.06 | 1.9e-05 | 6.0 | -5.4 | 8.5e-08 | -0.06 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | MED20 | 0.05 | 0.00 | blup | 50 | 0.04 | 2.8e-03 | 3.6 | 5.5 | 3.8e-08 | 0.06 | 0.04 | 0.49 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | UNC5CL | 0.06 | 0.07 | lasso | 4 | 0.04 | 3.3e-03 | 5.2 | -5.2 | 1.9e-07 | -0.05 | 0.02 | 0.71 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | MED20 | 0.04 | 0.03 | lasso | 3 | 0.04 | 7.3e-05 | -5.4 | 5.2 | 1.8e-07 | 0.04 | 0.04 | 0.93 | FALSE |
| 7 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | UBR2 | 0.10 | 0.01 | blup | 77 | 0.04 | 9.1e-03 | 5.7 | -6.0 | 1.6e-09 | -0.05 | 0.01 | 0.60 | TRUE |
| 8 | The Cancer Genome Atlas | Stomach Adenocarcinoma | MED20 | 0.03 | 0.05 | lasso | 2 | 0.04 | 1.2e-03 | -5.4 | 5.3 | 1.4e-07 | 0.06 | 0.03 | 0.76 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | UNC5CL | 0.04 | 0.02 | blup | 63 | 0.02 | 5.9e-03 | 4.5 | -5.3 | 1.1e-07 | -0.04 | 0.03 | 0.80 | TRUE |