[Hub]/) : Traits : BMI :

chr6:40,344,459-42,934,620

Best TWAS P=1.63e-09 · Best GWAS P=6.41e-29 conditioned to 2.43e-26

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts MED20 0.11 0.05 lasso 4 0.08 9.4e-07 -5.4 5.6 2.0e-08 0.01 0.20 0.78 TRUE
2 GTEx Testis NFYA 0.21 0.16 enet 9 0.10 4.3e-05 5.1 5.3 1.4e-07 0.04 0.07 0.93 FALSE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRPH2 0.07 0.03 enet 6 0.06 1.9e-05 6.0 -5.4 8.5e-08 -0.06 0.00 0.99 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma MED20 0.05 0.00 blup 50 0.04 2.8e-03 3.6 5.5 3.8e-08 0.06 0.04 0.49 FALSE
5 The Cancer Genome Atlas Colon Adenocarcinoma UNC5CL 0.06 0.07 lasso 4 0.04 3.3e-03 5.2 -5.2 1.9e-07 -0.05 0.02 0.71 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MED20 0.04 0.03 lasso 3 0.04 7.3e-05 -5.4 5.2 1.8e-07 0.04 0.04 0.93 FALSE
7 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma UBR2 0.10 0.01 blup 77 0.04 9.1e-03 5.7 -6.0 1.6e-09 -0.05 0.01 0.60 TRUE
8 The Cancer Genome Atlas Stomach Adenocarcinoma MED20 0.03 0.05 lasso 2 0.04 1.2e-03 -5.4 5.3 1.4e-07 0.06 0.03 0.76 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma UNC5CL 0.04 0.02 blup 63 0.02 5.9e-03 4.5 -5.3 1.1e-07 -0.04 0.03 0.80 TRUE