[Hub]/) : Traits : BMI : ← →

chr6:33,662,667-36,158,878

Best TWAS P=4.85e-49 · Best GWAS P=4.09e-45 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ANKS1A	0.15	0.12	lasso	7	0.12	2.4e-14	-5.6	-5.2	2.5e-07	0.04	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	C6orf106	0.29	0.21	bslmm	382	0.23	6.9e-28	11.1	8.6	1.2e-17	0.33	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PACSIN1	0.07	0.01	lasso	6	0.02	1.1e-03	11.3	10.5	6.6e-26	0.50	0.33	0.03	FALSE
4	CommonMind	Brain Pre-frontal Cortex	SNRPC	0.10	0.16	lasso	4	0.15	3.6e-18	14.1	-14.4	6.4e-47	-0.99	0.03	0.97	FALSE
5	CommonMind	Brain Pre-frontal Cortex	UHRF1BP1	0.17	0.23	lasso	19	0.22	5.8e-27	13.9	14.0	1.7e-44	1.00	0.04	0.96	FALSE
6	GTEx	Adipose Subcutaneous	UHRF1BP1	0.30	0.35	enet	28	0.36	1.6e-30	13.8	14.2	1.3e-45	0.98	0.07	0.93	FALSE
7	GTEx	Adipose Subcutaneous	SNRPC	0.13	0.13	enet	21	0.13	1.2e-10	13.8	-13.2	9.7e-40	-0.89	0.07	0.93	FALSE
8	GTEx	Adipose Visceral Omentum	UHRF1BP1	0.30	0.34	lasso	3	0.34	3.0e-18	13.9	13.9	8.5e-44	1.00	0.04	0.96	FALSE
9	GTEx	Adrenal Gland	UHRF1BP1	0.32	0.26	enet	33	0.33	1.3e-12	13.8	11.3	1.8e-29	0.89	0.04	0.96	FALSE
10	GTEx	Adrenal Gland	SNRPC	0.13	0.04	lasso	6	0.03	2.7e-02	12.3	-11.0	2.6e-28	-0.75	0.06	0.79	FALSE
11	GTEx	Artery Aorta	ANKS1A	0.10	0.10	lasso	2	0.08	2.4e-05	-8.5	-8.7	3.2e-18	-0.33	0.31	0.22	FALSE
12	GTEx	Artery Aorta	UHRF1BP1	0.35	0.32	lasso	10	0.30	7.7e-17	14.0	14.3	3.2e-46	1.00	0.03	0.97	FALSE
13	GTEx	Artery Aorta	SNRPC	0.06	0.03	enet	14	0.02	1.8e-02	13.4	-8.2	2.4e-16	-0.62	0.07	0.73	FALSE
14	GTEx	Artery Coronary	UHRF1BP1	0.33	0.36	lasso	2	0.35	1.6e-12	13.8	13.8	1.6e-43	0.99	0.04	0.96	FALSE
15	GTEx	Artery Tibial	UHRF1BP1	0.31	0.43	lasso	11	0.43	4.0e-36	13.8	13.4	5.3e-41	0.99	0.04	0.96	FALSE
16	GTEx	Artery Tibial	SNRPC	0.06	0.06	lasso	4	0.05	1.3e-04	13.9	-14.1	2.3e-45	-0.99	0.03	0.97	FALSE
17	GTEx	Artery Tibial	C6orf106	0.07	0.02	lasso	4	0.02	8.8e-03	8.5	-6.8	7.6e-12	-0.67	0.09	0.16	FALSE
18	GTEx	Brain Caudate basal ganglia	UHRF1BP1	0.19	0.14	lasso	7	0.12	3.1e-04	14.0	13.1	2.8e-39	0.98	0.04	0.92	FALSE
19	GTEx	Brain Caudate basal ganglia	SNRPC	0.19	0.15	lasso	3	0.06	7.7e-03	13.9	-14.5	6.5e-48	-0.98	0.04	0.92	FALSE
20	GTEx	Brain Cerebellar Hemisphere	UHRF1BP1	0.22	0.16	lasso	12	0.15	1.0e-04	13.9	14.0	1.1e-44	0.97	0.05	0.90	FALSE
21	GTEx	Brain Cerebellum	UHRF1BP1	0.14	0.09	enet	23	0.12	1.5e-04	14.0	12.4	2.1e-35	0.88	0.04	0.84	FALSE
22	GTEx	Brain Cortex	C6orf106	0.22	0.07	enet	16	0.10	1.1e-03	11.3	8.0	1.1e-15	0.42	0.47	0.11	FALSE
23	GTEx	Brain Frontal Cortex BA9	UHRF1BP1	0.18	0.00	lasso	10	0.02	7.3e-02	13.2	7.8	9.0e-15	0.73	0.04	0.68	FALSE
24	GTEx	Brain Frontal Cortex BA9	RPS10	0.21	0.08	lasso	3	0.06	8.6e-03	5.7	7.6	3.8e-14	0.07	0.12	0.05	TRUE
25	GTEx	Brain Putamen basal ganglia	UHRF1BP1	0.20	0.17	lasso	2	0.16	1.5e-04	14.0	14.0	1.2e-44	0.99	0.03	0.88	FALSE
26	GTEx	Breast Mammary Tissue	UHRF1BP1	0.34	0.28	enet	46	0.29	4.7e-15	13.9	11.8	5.6e-32	0.87	0.03	0.97	FALSE
27	GTEx	Breast Mammary Tissue (Male)	UHRF1BP1	0.19	0.16	enet	24	0.08	5.6e-03	14.0	14.0	1.4e-44	0.99	0.03	0.94	FALSE
28	GTEx	Breast Mammary Tissue (Female)	UHRF1BP1	0.23	0.21	lasso	3	0.20	1.0e-06	13.9	12.6	3.5e-36	0.95	0.04	0.96	FALSE
29	GTEx	Cells EBV-transformed lymphocytes	UHRF1BP1	0.37	0.08	enet	46	0.11	1.7e-04	13.9	8.7	2.8e-18	0.73	0.04	0.91	FALSE
30	GTEx	Cells EBV-transformed lymphocytes	C6orf106	0.20	0.00	lasso	5	0.00	2.7e-01	11.9	10.5	1.3e-25	0.48	0.07	0.09	FALSE
31	GTEx	Cells Transformed fibroblasts	DEF6	0.14	0.03	enet	35	0.04	9.7e-04	3.2	-5.5	5.1e-08	-0.27	0.60	0.03	FALSE
32	GTEx	Cells Transformed fibroblasts	UHRF1BP1	0.34	0.32	enet	44	0.31	2.4e-23	13.9	14.2	1.8e-45	0.96	0.07	0.93	FALSE
33	GTEx	Cells Transformed fibroblasts	RPS10	0.12	0.05	lasso	4	0.06	4.5e-05	8.1	7.5	4.3e-14	0.05	0.98	0.00	FALSE
34	GTEx	Colon Sigmoid	UHRF1BP1	0.44	0.36	lasso	12	0.38	1.8e-14	13.8	12.4	2.7e-35	0.93	0.03	0.97	FALSE
35	GTEx	Colon Transverse	UHRF1BP1	0.42	0.28	lasso	4	0.28	1.6e-13	13.9	14.4	9.4e-47	0.98	0.03	0.97	FALSE
36	GTEx	Colon Transverse	C6orf106	0.15	0.05	lasso	1	0.03	1.5e-02	9.5	9.5	2.1e-21	0.33	0.16	0.11	FALSE
37	GTEx	Esophagus Gastroesophageal Junction	UHRF1BP1	0.47	0.38	enet	22	0.43	7.3e-17	13.2	12.8	2.4e-37	0.90	0.04	0.96	FALSE
38	GTEx	Esophagus Mucosa	UHRF1BP1	0.14	0.15	enet	28	0.17	1.3e-11	14.0	14.2	1.8e-45	0.99	0.03	0.97	FALSE
39	GTEx	Esophagus Mucosa	SNRPC	0.12	0.10	lasso	2	0.08	4.8e-06	14.1	-14.1	6.5e-45	-1.00	0.03	0.97	FALSE
40	GTEx	Esophagus Muscularis	UHRF1BP1	0.42	0.35	enet	48	0.33	1.0e-20	13.9	13.5	1.1e-41	0.93	0.03	0.97	FALSE
41	GTEx	Esophagus Muscularis	SNRPC	0.09	0.11	lasso	3	0.07	3.8e-05	13.8	-13.7	5.6e-43	-0.98	0.05	0.95	FALSE
42	GTEx	Esophagus Muscularis	NUDT3	0.12	0.00	lasso	7	0.02	3.2e-02	8.4	-7.4	1.1e-13	-0.14	0.14	0.05	TRUE
43	GTEx	Heart Atrial Appendage	UHRF1BP1	0.13	0.07	enet	17	0.05	1.9e-03	13.9	10.8	3.6e-27	0.65	0.04	0.94	FALSE
44	GTEx	Heart Left Ventricle	UHRF1BP1	0.23	0.12	lasso	7	0.22	1.2e-11	13.9	11.4	2.9e-30	0.91	0.04	0.96	FALSE
45	GTEx	Liver	UHRF1BP1	0.13	0.04	lasso	3	0.05	1.8e-02	13.8	13.5	2.1e-41	0.86	0.04	0.81	FALSE
46	GTEx	Lung	UHRF1BP1	0.17	0.20	enet	22	0.18	4.3e-14	13.9	14.3	1.3e-46	0.99	0.04	0.96	FALSE
47	GTEx	Muscle Skeletal	UHRF1BP1	0.34	0.34	enet	45	0.39	4.3e-40	13.8	12.3	1.2e-34	0.91	0.10	0.90	FALSE
48	GTEx	Muscle Skeletal	SNRPC	0.03	0.02	lasso	3	0.02	8.3e-03	13.9	-14.3	1.5e-46	-0.99	0.04	0.90	FALSE
49	GTEx	Muscle Skeletal	C6orf106	0.08	0.06	lasso	4	0.06	7.1e-07	12.3	-13.0	1.4e-38	-0.70	0.69	0.30	FALSE
50	GTEx	Nerve Tibial	UHRF1BP1	0.31	0.31	lasso	6	0.31	3.9e-22	13.8	14.0	1.5e-44	0.99	0.04	0.96	FALSE
51	GTEx	Nerve Tibial	SNRPC	0.12	0.10	lasso	4	0.08	1.5e-06	13.8	-13.9	7.7e-44	-0.99	0.04	0.96	FALSE
52	GTEx	Nerve Tibial	C6orf106	0.11	0.07	enet	17	0.07	1.3e-05	11.2	8.8	1.3e-18	0.33	0.71	0.01	FALSE
53	GTEx	Pancreas	C6orf106	0.14	0.11	enet	11	0.13	2.8e-06	12.3	11.0	4.3e-28	0.56	0.83	0.04	FALSE
54	GTEx	Skin Not Sun Exposed Suprapubic	UHRF1BP1	0.20	0.10	enet	30	0.15	2.1e-08	14.0	10.3	4.9e-25	0.85	0.04	0.96	FALSE
55	GTEx	Skin Not Sun Exposed Suprapubic	SNRPC	0.18	0.04	enet	37	0.03	1.0e-02	14.0	-9.5	2.6e-21	-0.51	0.04	0.86	FALSE
56	GTEx	Skin Sun Exposed Lower leg	UHRF1BP1	0.19	0.13	enet	33	0.14	2.7e-11	13.8	12.8	2.8e-37	0.90	0.05	0.95	FALSE
57	GTEx	Skin Sun Exposed Lower leg	SNRPC	0.03	0.04	lasso	2	0.03	1.9e-03	13.8	-13.9	9.5e-44	-0.99	0.04	0.94	FALSE
58	GTEx	Small Intestine Terminal Ileum	UHRF1BP1	0.20	0.03	lasso	5	0.00	3.4e-01	13.9	13.7	7.8e-43	0.94	0.04	0.75	FALSE
59	GTEx	Spleen	UHRF1BP1	0.34	0.21	enet	36	0.17	4.5e-05	14.1	14.2	9.6e-46	0.86	0.03	0.95	FALSE
60	GTEx	Stomach	UHRF1BP1	0.24	0.22	enet	20	0.23	2.2e-11	13.2	14.1	2.1e-45	0.92	0.03	0.97	FALSE
61	GTEx	Testis	RPS10	0.17	0.11	lasso	1	0.04	5.2e-03	5.8	5.8	6.0e-09	-0.03	0.28	0.11	FALSE
62	GTEx	Thyroid	UHRF1BP1	0.13	0.06	enet	37	0.08	5.9e-07	5.3	9.0	2.0e-19	0.65	0.18	0.82	FALSE
63	GTEx	Thyroid	SNRPC	0.07	0.04	lasso	6	0.05	1.6e-04	13.9	-13.8	4.3e-43	-0.99	0.06	0.93	FALSE
64	GTEx	Thyroid	C6orf106	0.09	0.01	enet	29	0.01	1.1e-01	11.4	8.1	4.3e-16	0.36	0.09	0.04	TRUE
65	GTEx	Uterus	UHRF1BP1	0.20	0.03	lasso	4	0.07	1.8e-02	13.8	14.7	4.8e-49	0.86	0.04	0.66	TRUE
66	GTEx	Vagina	UHRF1BP1	0.31	0.05	lasso	8	0.04	5.0e-02	13.8	13.3	1.9e-40	0.96	0.04	0.79	FALSE
67	GTEx	Whole Blood	UHRF1BP1	0.14	0.14	lasso	7	0.14	2.9e-13	13.9	13.3	1.3e-40	0.97	0.05	0.95	FALSE
68	METSIM	Adipose	C6orf106	0.04	0.02	blup	381	0.02	7.7e-04	8.4	9.8	1.5e-22	0.34	0.36	0.18	FALSE
69	METSIM	Adipose	SNRPC	0.05	0.05	lasso	7	0.07	2.9e-11	14.0	-11.6	3.3e-31	-0.94	0.04	0.96	FALSE
70	METSIM	Adipose	UHRF1BP1	0.16	0.31	enet	30	0.32	1.0e-49	13.9	13.1	4.9e-39	0.98	0.05	0.95	FALSE
71	NTR	Blood	C6orf106	0.03	0.02	lasso	6	0.02	7.2e-07	11.3	10.8	2.6e-27	0.56	0.99	0.01	FALSE
72	NTR	Blood	UHRF1BP1	0.03	0.05	enet	19	0.05	7.4e-15	13.5	13.4	6.0e-41	0.98	0.06	0.94	FALSE
73	ROSMAP	Brain Pre-frontal Cortex	TEAD3	0.07	0.03	bslmm	421	0.04	5.6e-06	4.9	-6.1	1.1e-09	-0.27	0.80	0.00	FALSE
74	ROSMAP	Brain Pre-frontal Cortex	ANKS1A	0.18	0.18	lasso	5	0.16	1.3e-20	-5.6	-5.2	1.6e-07	0.04	1.00	0.00	TRUE
75	ROSMAP	Brain Pre-frontal Cortex	UHRF1BP1	0.16	0.27	lasso	10	0.28	2.7e-36	13.5	13.6	3.1e-42	0.99	0.05	0.95	FALSE
76	ROSMAP	Brain Pre-frontal Cortex	PACSIN1	0.09	0.00	blup	359	0.02	4.5e-04	11.1	6.2	6.4e-10	0.32	0.19	0.04	FALSE
77	ROSMAP	Brain Pre-frontal Cortex	SNRPC	0.15	0.27	lasso	4	0.27	4.0e-35	13.9	-13.9	4.6e-44	-0.99	0.05	0.95	FALSE
78	ROSMAP	Brain Pre-frontal Cortex	C6orf106	0.30	0.26	bslmm	372	0.33	9.3e-44	11.3	7.0	1.9e-12	0.22	1.00	0.00	FALSE
79	YFS	Blood	SNRPC	0.02	0.03	lasso	5	0.02	3.0e-08	13.2	-13.2	1.7e-39	-0.86	0.19	0.81	FALSE
80	YFS	Blood	UHRF1BP1	0.18	0.34	enet	36	0.34	2.5e-117	14.1	14.2	6.9e-46	0.99	0.04	0.96	FALSE
81	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UHRF1BP1	0.03	0.04	lasso	3	0.04	1.7e-04	13.9	13.9	1.3e-43	0.99	0.02	0.95	FALSE
82	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS10	0.01	0.01	enet	1	0.01	1.2e-02	5.4	5.4	7.5e-08	0.21	0.18	0.02	TRUE
83	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNRPC	0.01	0.01	blup	31	0.00	3.0e-02	8.5	-13.6	5.8e-42	-0.97	0.01	0.65	FALSE
84	The Cancer Genome Atlas	Breast Invasive Carcinoma	UHRF1BP1	0.04	0.05	lasso	3	0.04	8.4e-09	14.0	14.0	3.0e-44	1.00	0.02	0.98	FALSE
85	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	UHRF1BP1	0.07	0.11	lasso	3	0.07	2.6e-04	13.9	13.9	1.3e-43	1.00	0.02	0.97	FALSE
86	The Cancer Genome Atlas	Colon Adenocarcinoma	UHRF1BP1	0.08	0.11	lasso	12	0.10	2.3e-06	13.9	13.9	1.2e-43	0.99	0.01	0.99	FALSE
87	The Cancer Genome Atlas	Esophageal Carcinoma	UHRF1BP1	0.19	0.20	lasso	10	0.17	5.2e-06	13.9	13.9	8.0e-44	1.00	0.02	0.98	FALSE
88	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SNRPC	0.06	0.07	lasso	2	0.07	6.7e-08	13.9	-13.9	6.3e-44	-1.00	0.02	0.98	FALSE
89	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UHRF1BP1	0.06	0.06	enet	8	0.06	1.3e-07	13.5	11.3	1.5e-29	0.86	0.02	0.98	FALSE
90	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf106	0.04	0.01	blup	68	0.01	2.4e-02	11.3	8.2	3.5e-16	0.35	0.04	0.05	FALSE
91	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UHRF1BP1	0.18	0.28	lasso	5	0.27	1.0e-30	13.9	14.0	1.6e-44	0.99	0.02	0.98	FALSE
92	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UHRF1BP1	0.08	0.09	blup	71	0.10	2.0e-06	13.9	12.9	6.1e-38	0.91	0.02	0.98	FALSE
93	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf106	0.04	0.05	lasso	4	0.03	8.1e-05	11.4	11.4	4.0e-30	0.59	0.98	0.01	FALSE
94	The Cancer Genome Atlas	Brain Lower Grade Glioma	UHRF1BP1	0.06	0.05	blup	70	0.04	8.6e-06	8.5	10.9	1.7e-27	0.87	0.05	0.95	FALSE
95	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	UHRF1BP1	0.12	0.09	blup	70	0.06	5.6e-04	14.0	12.8	1.0e-37	0.94	0.01	0.97	FALSE
96	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf106	0.03	0.03	lasso	3	0.01	7.6e-03	8.4	9.9	5.0e-23	0.49	0.10	0.25	FALSE
97	The Cancer Genome Atlas	Lung Adenocarcinoma	UHRF1BP1	0.06	0.07	enet	20	0.08	6.4e-10	14.0	13.2	8.9e-40	0.98	0.01	0.99	FALSE
98	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UHRF1BP1	0.04	0.06	blup	70	0.06	1.5e-07	13.9	11.9	1.9e-32	0.90	0.02	0.98	FALSE
99	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf106	0.14	0.07	enet	6	0.06	1.0e-04	11.3	8.1	4.3e-16	0.38	0.41	0.04	FALSE
100	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	UHRF1BP1	0.06	0.07	lasso	1	0.05	1.5e-04	13.5	13.5	2.0e-41	0.96	0.02	0.98	FALSE
101	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	UHRF1BP1	0.20	0.23	lasso	16	0.25	8.3e-11	13.9	13.8	3.0e-43	0.99	0.01	0.99	FALSE
102	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UHRF1BP1	0.13	0.09	enet	13	0.10	6.4e-05	13.9	11.7	2.2e-31	0.90	0.02	0.97	FALSE
103	The Cancer Genome Atlas	Prostate Adenocarcinoma	UHRF1BP1	0.10	0.20	lasso	5	0.19	1.6e-19	14.0	13.6	3.1e-42	0.99	0.02	0.98	FALSE
104	The Cancer Genome Atlas	Soft Tissue Sarcoma	UHRF1BP1	0.08	0.09	blup	71	0.08	1.0e-05	13.9	13.0	1.0e-38	0.93	0.01	0.98	FALSE
105	The Cancer Genome Atlas	Stomach Adenocarcinoma	UHRF1BP1	0.08	0.10	lasso	1	0.10	7.1e-08	13.9	13.9	4.5e-44	0.99	0.02	0.98	FALSE
106	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PPARD	0.12	0.10	lasso	5	0.05	5.3e-03	4.9	-5.2	2.3e-07	-0.27	0.13	0.64	FALSE
107	The Cancer Genome Atlas	Thyroid Carcinoma	SNRPC	0.05	0.05	blup	31	0.05	2.9e-05	14.0	-13.8	1.5e-43	-0.94	0.01	0.98	FALSE
108	The Cancer Genome Atlas	Thyroid Carcinoma	UHRF1BP1	0.07	0.03	blup	71	0.05	2.8e-05	14.0	10.4	3.3e-25	0.87	0.01	0.98	FALSE
109	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SNRPC	0.09	0.11	lasso	2	0.10	8.1e-04	13.9	-13.9	9.0e-44	-0.99	0.01	0.81	FALSE