[Hub]/) : Traits : Cardiovascular Disease :

chr17:73,128,150-74,629,867

Best TWAS P=6.44e-11 · Best GWAS P=7.57e-12 conditioned to 0.0386

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous TRIM65 0.10 0.07 lasso 4 0.05 3.0e-05 -5.4 -5.5 4.0e-08 0.77 0.04 0.96 FALSE
2 GTEx Adipose Subcutaneous FBF1 0.36 0.29 lasso 2 0.29 5.4e-24 -6.5 -6.5 8.9e-11 0.89 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous MRPL38 0.08 0.07 lasso 4 0.06 9.3e-06 -5.5 6.1 9.9e-10 -0.88 0.04 0.96 FALSE
4 GTEx Adipose Visceral Omentum FBF1 0.29 0.23 lasso 1 0.22 1.4e-11 -6.5 -6.5 1.1e-10 0.88 0.01 0.99 FALSE
5 GTEx Artery Aorta FBF1 0.32 0.27 lasso 2 0.26 2.2e-14 -6.5 -6.4 1.3e-10 0.89 0.01 0.99 FALSE
6 GTEx Artery Coronary FBF1 0.41 0.18 lasso 8 0.14 2.2e-05 -6.5 -5.9 4.0e-09 0.86 0.01 0.99 FALSE
7 GTEx Artery Tibial FBF1 0.36 0.33 enet 12 0.33 3.7e-26 -6.5 -6.5 7.1e-11 0.92 0.01 0.99 FALSE
8 GTEx Brain Caudate basal ganglia FBF1 0.35 0.20 enet 27 0.19 3.3e-06 -6.5 -6.1 9.6e-10 0.83 0.03 0.96 FALSE
9 GTEx Brain Cortex FBF1 0.34 0.25 lasso 3 0.25 1.5e-07 -5.4 -5.8 8.7e-09 0.79 0.07 0.92 FALSE
10 GTEx Brain Nucleus accumbens basal ganglia FBF1 0.29 0.32 lasso 2 0.29 1.9e-08 -5.4 -5.4 7.4e-08 0.76 0.04 0.94 FALSE
11 GTEx Breast Mammary Tissue FBF1 0.15 0.20 lasso 3 0.19 6.9e-10 -6.5 -6.5 1.0e-10 0.89 0.02 0.98 FALSE
12 GTEx Breast Mammary Tissue (Female) FBF1 0.14 0.13 lasso 3 0.13 1.2e-04 -4.8 -5.3 1.2e-07 0.78 0.06 0.61 FALSE
13 GTEx Cells Transformed fibroblasts FBF1 0.14 0.08 lasso 5 0.07 5.1e-06 -6.5 -5.7 1.2e-08 0.79 0.02 0.97 FALSE
14 GTEx Colon Sigmoid FBF1 0.38 0.10 enet 19 0.17 1.5e-06 -6.8 -5.5 3.1e-08 0.87 0.00 1.00 FALSE
15 GTEx Colon Transverse TRIM65 0.32 0.13 lasso 6 0.12 3.1e-06 -6.5 -5.2 1.6e-07 0.83 0.00 1.00 FALSE
16 GTEx Colon Transverse FBF1 0.28 0.21 lasso 3 0.19 2.8e-09 -6.5 -6.4 1.3e-10 0.86 0.01 0.99 FALSE
17 GTEx Esophagus Gastroesophageal Junction FBF1 0.33 0.16 lasso 6 0.13 2.3e-05 -5.4 -5.9 4.4e-09 0.84 0.01 0.98 FALSE
18 GTEx Esophagus Muscularis FBF1 0.34 0.33 lasso 3 0.32 5.5e-20 -6.5 -6.5 1.0e-10 0.88 0.01 0.99 FALSE
19 GTEx Lung UNC13D 0.12 0.09 enet 15 0.10 3.4e-08 -5.8 -5.6 1.8e-08 0.78 0.09 0.91 FALSE
20 GTEx Lung FBF1 0.20 0.18 lasso 1 0.17 2.6e-13 -6.5 -6.5 1.1e-10 0.88 0.01 0.99 FALSE
21 GTEx Muscle Skeletal FBF1 0.07 0.02 lasso 4 0.02 8.0e-03 -5.4 -5.6 2.0e-08 0.83 0.03 0.95 FALSE
22 GTEx Nerve Tibial FBF1 0.54 0.46 enet 37 0.45 2.9e-35 -6.5 -6.0 1.6e-09 0.86 0.01 0.99 FALSE
23 GTEx Nerve Tibial MRPL38 0.14 0.10 lasso 3 0.11 2.9e-08 -4.6 5.1 2.8e-07 -0.74 0.74 0.26 FALSE
24 GTEx Nerve Tibial RP11-552F3.9 0.14 0.05 lasso 5 0.07 2.0e-05 -6.2 5.2 2.2e-07 -0.72 0.02 0.95 FALSE
25 GTEx Pituitary FBF1 0.34 0.37 lasso 4 0.39 7.6e-11 -6.5 -6.2 5.3e-10 0.89 0.01 0.98 FALSE
26 GTEx Prostate FBF1 0.26 0.24 lasso 1 0.20 1.2e-05 -6.5 -6.5 1.1e-10 0.88 0.01 0.99 FALSE
27 GTEx Skin Sun Exposed Lower leg TRIM47 0.09 0.03 lasso 3 0.03 1.5e-03 -6.2 6.5 1.0e-10 -0.89 0.01 0.99 FALSE
28 GTEx Skin Sun Exposed Lower leg FBF1 0.22 0.23 lasso 1 0.21 3.0e-17 -6.5 -6.5 1.1e-10 0.88 0.01 0.99 FALSE
29 GTEx Stomach FBF1 0.28 0.17 enet 12 0.17 1.5e-08 -6.5 -6.5 6.4e-11 0.94 0.00 1.00 TRUE
30 GTEx Testis FBF1 0.37 0.38 lasso 2 0.38 8.4e-18 -6.5 -6.5 1.1e-10 0.88 0.01 0.99 FALSE
31 GTEx Thyroid WBP2 0.07 0.06 lasso 2 0.06 4.1e-05 -5.1 -5.5 4.0e-08 0.79 0.26 0.59 FALSE
32 GTEx Thyroid TRIM65 0.19 0.11 lasso 2 0.09 3.5e-07 -6.5 -6.1 8.9e-10 0.85 0.02 0.98 FALSE
33 GTEx Thyroid FBF1 0.24 0.23 lasso 2 0.23 8.0e-18 -6.5 -6.1 9.9e-10 0.87 0.01 0.99 FALSE
34 GTEx Thyroid MRPL38 0.15 0.07 lasso 3 0.09 1.1e-07 -4.9 5.4 6.7e-08 -0.74 0.44 0.56 FALSE
35 METSIM Adipose FBF1 0.20 0.09 enet 41 0.12 2.5e-17 -6.5 -5.3 9.3e-08 0.69 0.02 0.98 FALSE
36 METSIM Adipose TRIM65 0.13 0.03 enet 24 0.06 1.4e-09 -6.8 -5.8 5.0e-09 0.70 0.00 1.00 FALSE
37 The Cancer Genome Atlas Glioblastoma Multiforme TRIM65 0.08 0.02 enet 7 0.04 1.9e-02 -4.7 -5.2 2.3e-07 0.72 0.02 0.48 FALSE
38 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma FBF1 0.08 0.05 blup 41 0.04 1.1e-02 -4.8 -5.8 8.4e-09 0.78 0.01 0.88 FALSE
39 The Cancer Genome Atlas Thyroid Carcinoma TRIM47 0.06 0.06 blup 30 0.06 1.6e-06 -6.1 5.1 2.9e-07 -0.69 0.14 0.86 FALSE