Best TWAS P=7.87e-13 · Best GWAS P=4.87e-64 conditioned to 9.93e-38
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | PVRL2 | 0.15 | 0.01 | enet | 10 | 0.02 | 1.7e-02 | -6.8 | 5.4 | 7.1e-08 | -0.16 | 0.14 | 0.04 | FALSE |
| 2 | GTEx | Stomach | BCAM | 0.33 | 0.00 | enet | 3 | 0.01 | 9.6e-02 | 3.3 | -6.7 | 1.5e-11 | 0.27 | 0.07 | 0.08 | TRUE |
| 3 | YFS | Blood | TOMM40 | 0.04 | 0.00 | bslmm | 371 | 0.01 | 2.6e-04 | -5.7 | 5.6 | 2.2e-08 | -0.08 | 0.05 | 0.02 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | APOC4 | 0.06 | 0.03 | blup | 34 | 0.04 | 8.4e-06 | 1.9 | 5.4 | 8.0e-08 | -0.19 | 0.66 | 0.06 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | PVRL2 | 0.09 | 0.05 | blup | 55 | 0.03 | 4.6e-04 | 2.8 | -7.2 | 7.9e-13 | 0.31 | 0.46 | 0.09 | TRUE |