TWAS hub - ZNF831

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.195	0.0248	0.0000	0.145	0.165	0.192	0.193	0.190	5.5e-45	1.4e-51	9.3e-61	7.8e-61	5.8e-60
2	TCGA	Skin Cutaneous Melanoma	0.218	0.0870	0.0015	0.026	0.096	0.148	NA	0.115	6.8e-02	1.5e-03	9.0e-05	NA	5.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Blood pressure	17.2	32.8	64.2	-1.2	-8.0
Vascular/heart problems diagnosed by doctor	15.3	41.6	83.0	0.4	9.1
Cardiovascular Disease	13.6	44.8	87.9	-1.3	-9.4
Hypertension (Self-reported)	13.5	37.6	75.2	0.2	-8.7
High blood pressure	13.4	37.4	74.7	0.3	-8.6
Number of self-reported non-cancer illnesses	12.4	21.5	39.5	-1.9	-6.3
Medication for cholesterol, blood pressure or diabetes	11.1	18.4	34.9	1.3	5.9
Systolic Blood Pressure	9.8	49.2	97.5	-0.9	-9.9
Number of treatments/medications taken	9.4	16.9	31.3	-1.6	-5.6
Medication: Lisinopril	9.1	11.8	20.2	-1.8	-4.5
Medication: Blood pressure	8.8	15.4	30.7	-0.4	-5.5
Medication for cholesterol	7.6	11.6	23.0	0.4	4.8
Medication: Bendroflumethiazide	7.6	11.6	22.7	-0.7	-4.8
Irritable Bowel Disease (IBD)	7.3	17.4	32.3	-5.7	-1.6
High blood pressure (mother)	7.2	10.1	19.8	-0.6	-4.4
Medication: Simvastatin	7.1	10.4	20.4	-0.6	-4.5
Diastolic blood pressure, automated reading	6.9	21.5	42.9	0.1	-6.6
Heart attack	6.4	8.2	16.0	0.6	-4.0
Medication: Cholesterol lowering	6.2	9.6	19.1	-0.3	-4.4
Systolic blood pressure, automated reading	6.0	17.5	34.3	0.9	-5.9
Ulcerative Colitis	5.7	8.3	14.7	-3.8	-1.4
Medication: Aspirin	5.3	7.0	12.5	-1.2	-3.5
Heart attack/myocardial infarction (self-reported)	5.3	6.9	13.3	0.7	-3.6
Ulcerative Colitis (UC)	5.1	9.5	18.2	-4.3	-0.9
Hair Pigment	4.9	140.9	141.8	-11.8	-11.9
Taking other prescription medications	4.9	7.6	9.8	-2.3	-3.1
Illnesses of mother	4.9	6.0	11.6	0.6	3.4
Primary Biliary Cirrhosis	4.8	6.9	9.0	-3.0	-2.2
Medication: Amlodipine	4.6	6.5	12.9	-0.3	-3.6
Hair/balding pattern: Pattern 2	4.4	5.6	8.2	2.9	1.7
Illnesses of siblings	4.4	6.2	9.0	1.8	3.0
Medication: Aspirin	4.2	5.4	9.0	-1.4	-3.0
Medication: Ramipril	4.1	5.3	9.4	1.1	-3.1
Handedness (chirality/laterality): Left-handed	4.1	5.0	7.6	2.8	-1.5
Crohns Disease (2017)	4.0	8.9	17.3	-4.2	-0.7
High blood pressure (siblings)	3.9	5.6	10.3	-0.9	-3.2
Rheumatoid Arthritis	3.7	5.1	5.2	-2.3	-2.2
Medication for pain relief, constipation, heartburn	3.7	6.3	11.8	0.9	3.4
Angina (self-reported)	3.7	4.8	9.4	-0.5	-3.1
Cholesterol lowering medication	3.7	5.5	9.7	1.1	-3.1
Angina	3.5	4.6	8.7	-0.6	-3.0
Medication: Atenolol	3.4	4.3	8.1	-0.6	-2.9
Other serious medical condition/disability diagnosed by doctor	3.3	4.2	4.8	-1.9	-2.2
Overall health rating	3.2	6.9	13.5	-0.5	-3.7
Deep venous thrombosis (DVT) (self-reported)	3.1	4.0	7.2	-0.8	-2.7
Crohns Disease (2012)	3.0	4.8	9.2	-3.0	-0.6
Medication: Atorvastatin	3.0	3.7	5.9	2.4	-1.2
Eye problems/disorders: None of the above	2.9	3.3	3.8	-2.0	-1.7
Leg pain on walking	2.9	3.7	6.9	-0.7	2.6
Knee pain experienced in last month	2.9	4.5	7.5	-2.7	-1.3
Alcohol drinker status: Never	2.9	3.5	6.9	-2.6	-0.1
Qualifications: A levels/AS levels or equivalent	2.8	6.2	9.2	1.8	3.0
Diabetes diagnosed by doctor	2.8	4.7	9.0	3.0	-0.6
Asthma (self-reported)	2.8	5.6	10.0	-3.2	-1.1
Blood clot in the leg (DVT)	2.7	3.5	6.5	-0.8	-2.6
Illnesses of siblings: Diabetes	2.7	3.3	4.3	-1.5	-2.1
Number of operations (self-reported)	2.7	4.0	7.5	-0.7	-2.7
Asthma	2.6	5.0	9.4	-3.1	-0.9
Chronic bronchitis/emphysema (mother)	2.6	3.0	5.2	-2.3	0.9
Long-standing illness, disability or infirmity	2.6	4.0	5.7	-1.5	-2.4
High cholesterol (Self-reported)	2.6	4.6	7.7	1.2	-2.8
Medication: Paracetamol	2.5	3.9	5.7	-1.4	-2.4
Allergy	2.4	5.5	9.7	3.1	1.1
Chest pain or discomfort	2.4	3.5	4.5	-2.1	-1.6
Supplements: Calcium	2.2	2.5	4.7	2.2	-0.5
Verbal and Numeric Reasoning (VNR)	2.1	5.1	6.7	1.9	2.6
Medication: Paracetamol	2.1	3.5	4.9	-1.5	-2.2
Eye problems/disorders: Cataract	2.1	2.4	4.8	0.3	2.2
Blood Eosinophil Count	2.0	15.5	21.6	-3.1	-4.6
Hayfever, allergic rhinitis or eczema	2.0	4.2	8.4	-2.9	-0.2
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	3.6	1.7	1.9
Ever had bowel cancer screening	2.0	2.3	4.5	0.2	-2.1
Heart disease (siblings)	2.0	2.5	3.1	-1.4	-1.8
Medication for hormone replacement therapy	1.9	2.1	4.2	0.1	2.1
Medication: Co-codamol	1.9	2.1	4.2	-2.1	0.2
Stomach or abdominal pain in last month	1.9	2.4	4.4	-2.1	-0.6
Hair/balding pattern: Pattern 3	1.9	2.8	3.4	-1.5	-1.8
Medication: Gliclazide	1.9	2.2	4.4	2.1	0.1
Ever had prostate specific antigen (PSA) test	1.9	2.2	4.0	0.6	-2.0
Medication: Metformin	1.8	2.5	4.7	2.2	-0.5
Mouth/teeth dental problems: Bleeding gums	1.8	2.4	4.4	-2.1	0.6
Age at first live birth	1.8	3.1	5.3	-1.0	-2.3
Illnesses of father: None of the above (group 1)	1.8	2.2	3.1	1.2	1.8
Wears glasses or contact lenses	1.8	2.1	2.6	1.6	-1.3
Illnesses of father: High blood pressure	1.8	2.2	3.0	1.2	-1.7
Allergy or Eczema	1.7	4.6	8.8	-3.0	-0.6
Number of incorrect matches in round	1.7	2.8	4.9	-0.8	-2.2
Diabetes (father)	1.6	1.9	3.7	1.9	0.4
Current tobacco smoking	1.6	2.7	5.4	2.3	-0.0
Age when periods started (menarche)	1.6	3.9	6.7	-1.0	-2.6
Qualifications: None of the above	1.6	3.4	3.8	-1.7	-1.9
Diabetes (self-reported)	1.6	2.4	4.7	2.2	-0.5
Ever taken oral contraceptive pill	1.6	1.8	2.7	-1.0	-1.7
Height	1.5	29.4	56.7	1.5	-7.5
Sitting height	1.5	10.3	20.4	-0.4	-4.5
Pulse wave Arterial Stiffness index	1.5	1.7	1.8	1.3	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.4	4.5	-0.5	2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	3.4	1.9	-0.2
Intelligence (Savage-Jansen 2018)	1.4	4.2	4.8	1.9	2.2
Falls in the last year	1.4	1.9	2.5	-1.1	-1.6
Standing height	1.4	13.5	26.8	-0.3	-5.2
Medication: Omeprazole	1.4	1.7	2.0	1.2	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	1.8	-1.4	1.2
Smoking status: Current	1.4	2.2	4.2	2.0	-0.5
Worry (Nagel 2018)	1.3	2.8	4.4	-1.1	-2.1
Reaction Time	1.3	2.5	4.6	-2.2	-0.6
Bipolar Disorder (2011)	1.3	1.2	2.4	-1.5	0.2
Type 2 Diabetes (T2D) (2018)	1.3	2.4	3.9	2.0	-0.9
Hand grip strength (left)	1.3	3.3	4.8	-1.4	-2.2
Tense / ‘highly strung’	1.3	2.2	2.2	-1.5	-1.5
Had major operations	1.3	1.5	2.9	-0.3	-1.7
Friendships satisfaction	1.3	1.6	2.7	1.6	0.7
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	2.0	1.1	-1.4
Alzheimer’s Disease (in mother)	1.2	1.4	2.7	1.6	-0.3
Respiratory disease	1.2	2.7	3.6	-1.9	-1.3
Qualifications: CSEs or equivalent	1.2	1.6	1.8	-1.3	-1.2
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	1.7	-1.1	-1.3
Headache pain in last month	1.2	2.1	3.6	-1.9	-0.8
Wheeze or whistling in the chest in last year	1.2	2.1	3.4	-0.9	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	1.4	1.1	-1.2
Qualifications: nursing, teaching	1.2	1.9	2.8	1.7	1.0
Back pain experienced in last month	1.2	1.8	2.4	-1.1	-1.5
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.4	1.6	-0.1
Multivitamins +/- minerals	1.1	1.4	1.5	1.2	1.2
Had menopause	1.1	1.3	2.7	1.6	0.0
Pulse wave peak to peak time	1.1	1.3	1.5	-1.2	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	1.6	-1.3	1.1
Family relationship satisfaction	1.1	1.4	2.2	1.5	0.8
Illnesses of father: Heart disease	1.1	1.5	2.6	-0.6	-1.6
Guilty feelings	1.1	1.7	1.8	1.3	1.4
Pain experienced in last month	1.1	1.9	2.9	1.7	0.9
Alzheimer’s Disease (in father)	1.0	1.1	1.9	0.4	1.4
Ever had hysterectomy (womb removed)	1.0	1.2	1.4	-1.0	-1.2
Weight	1.0	4.9	9.2	-0.7	-3.0
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.1	-0.6	-1.4
Heart disease (mother)	1.0	1.2	1.9	-0.6	-1.4
Suffer from ‘nerves’	1.0	1.5	2.1	-0.9	-1.5
Supplements: Vitamin C	1.0	1.2	1.6	0.9	-1.3
Mother’s age at death	1.0	1.2	1.7	1.3	0.8
Unable to work because of sickness or disability	1.0	1.4	2.6	-0.4	-1.6
Basal cell carcinoma (self-reported)	1.0	1.1	1.2	-1.0	1.1
Arm predicted mass (left)	1.0	5.2	9.4	-1.0	-3.1
Breast Cancer	0.9	2.3	3.2	1.2	1.8
Mean Putamen Volume	0.9	1.1	2.1	-0.2	1.5
Average weekly spirits intake	0.9	1.2	1.9	-1.4	-0.6
Leg fat-free mass (left)	0.9	4.6	8.7	-0.7	-3.0
Maternal smoking around birth	0.9	1.2	1.3	-1.2	1.1
Leg predicted mass (left)	0.9	5.0	9.4	-0.8	-3.1
Trunk fat mass	0.9	3.9	7.4	-0.6	-2.7
Peak expiratory flow (PEF)	0.9	2.0	4.1	-2.0	0.2
Pulse wave reflection index	0.9	1.1	1.6	-1.3	-0.8
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.2	-0.2	1.5
Basal metabolic rate	0.9	5.1	9.5	-0.8	-3.1
Hearing difficulty/problems: Yes	0.8	1.3	2.2	-1.5	-0.6
Fed-up feelings	0.8	1.5	2.5	-1.6	-0.7
Medication: Levothyroxine sodium	0.8	1.4	1.8	-1.3	-1.0
Trunk fat-free mass	0.8	4.6	8.6	-0.8	-2.9
Mouth/teeth dental problems: Dentures	0.8	1.4	2.7	1.6	0.3
Trunk predicted mass	0.8	4.8	8.8	-0.9	-3.0
Medication: Seretide 50 evohaler	0.8	0.9	1.7	-0.1	-1.3
Whole body fat mass	0.8	3.2	6.0	-0.6	-2.4
Whole body fat-free mass	0.8	4.7	8.8	-0.8	-3.0
Leg fat-free mass (right)	0.8	4.1	8.2	-0.3	-2.9
Mineral and other dietary supplements	0.8	1.0	2.1	-1.4	0.1
Whole body water mass	0.8	4.6	8.5	-0.8	-2.9
Leg predicted mass (right)	0.8	4.5	8.8	-0.4	-3.0
Eye problems/disorders: Glaucoma	0.8	1.0	1.9	1.4	0.2
Arm fat-free mass (left)	0.8	4.2	7.5	-1.0	-2.7
Depressed Affect (Nagel 2018)	0.7	1.4	1.9	-1.0	-1.4
Prostate Cancer	0.7	1.0	2.0	1.4	0.2
Coronary Artery Disease (CAD)	0.7	0.9	1.2	-1.1	-0.8
HDL Cholesterol	0.7	1.2	2.4	-1.5	-0.3
Neuroticism (2016)	0.7	1.0	2.0	-1.4	0.1
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.6	1.3	-0.1
Heel T-Score	0.7	5.2	8.7	1.3	3.0
Hypothyroidism (self reported)	0.7	1.5	2.6	-1.6	-0.7
Chronic bronchitis/emphysema (father)	0.7	0.8	1.6	-1.3	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	1.7	1.3	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	1.6	1.3	-0.1
Arm fat mass (right)	0.7	2.7	5.3	-0.4	-2.3
Birth weight of first child	0.7	1.3	2.0	-1.4	-0.8
Arm predicted mass (right)	0.7	3.8	4.6	-1.7	-2.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	0.9	-1.0	0.9
Miserableness	0.7	1.1	2.0	-1.4	-0.5
Schizophrenia vs Biploar Disorder	0.6	0.8	1.4	-0.3	-1.2
Blood Platelet Count	0.6	6.7	7.9	-2.8	-2.3
Blood White Count	0.6	4.7	9.1	-3.0	-0.5
Severe depression (siblings)	0.6	0.7	1.0	1.0	0.6
Trunk fat percentage	0.6	2.5	4.7	-0.6	-2.2
Hand grip strength (right)	0.6	1.5	1.9	-1.4	-1.1
Pulse rate	0.6	1.0	2.0	1.4	-0.1
Arm fat-free mass (right)	0.6	3.0	3.9	-1.5	-2.0
Comparative height size at age 10	0.6	3.5	6.4	-0.8	-2.5
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.8	-1.3	-0.2
Breast cancer (self-reported)	0.6	0.7	0.9	-0.6	-1.0
Hearing aid user	0.6	0.7	1.1	-1.1	-0.6
Chronotype (morning person)	0.5	1.0	2.0	-0.2	-1.4
Townsend deprivation index at recruitment	0.5	0.7	1.1	-0.5	-1.0
Financial difficulties in last 2 years	0.5	0.7	1.1	-0.6	1.0
Arm fat percentage (right)	0.5	1.8	3.6	-0.2	-1.9
Happiness	0.5	0.6	1.2	-0.2	1.1
Length of working week for main job	0.5	0.5	1.1	0.1	1.0
Breastfed as a baby	0.5	0.7	1.3	1.1	0.2
Hair/balding pattern: Pattern 4	0.5	1.3	1.4	-1.2	-1.1
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	1.7	-1.3	-0.4
Body fat percentage	0.5	2.0	3.5	-0.7	-1.9
Number of full brothers	0.5	0.7	1.3	-1.2	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	0.7	0.7	-0.8
Alcohol intake frequency.	0.5	1.3	1.5	-1.0	-1.2
Smoking status: Previous	0.5	0.7	1.1	-1.1	-0.5
Arm fat mass (left)	0.5	1.9	3.5	-0.5	-1.9
Financial situation satisfaction	0.5	0.7	1.2	1.1	0.3
LDL Cholesterol	0.4	0.6	1.0	1.0	0.5
Triglycerides	0.4	0.6	0.6	0.8	0.8
Relative age voice broke	0.4	0.6	1.1	1.0	-0.4
Serious illness, injury or assault to yourself	0.4	0.5	0.5	0.7	-0.7
Waist circumference	0.4	1.6	2.7	-0.7	-1.6
Alcohol usually taken with meals	0.4	0.6	1.1	-0.0	1.1
Had other major operations	0.4	0.5	0.9	0.1	-1.0
Neuroticism score	0.4	0.9	1.3	-1.1	-0.8
Hip circumference	0.4	1.9	3.8	-0.2	-1.9
Worrier / anxious feelings	0.4	0.8	1.3	-0.6	-1.2
Medication: Lansoprazole	0.4	0.5	0.9	0.2	-0.9
Forced vital capacity (FVC), Best measure	0.4	1.6	1.7	-1.3	-1.2
Health satisfaction	0.4	0.6	0.7	0.9	-0.6
Medication: Ibuprofen	0.4	0.5	1.0	1.0	-0.3
Medication: Allopurinol	0.4	0.6	1.0	1.0	0.5
Leg fat mass (right)	0.4	1.4	2.1	-0.8	-1.5
Age at last live birth	0.4	0.6	1.2	-0.0	-1.1
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.8	0.9	0.1
Ever smoked	0.4	0.7	1.3	1.1	-0.3
Neuroticism (Nagel 2018)	0.3	0.7	1.0	-1.0	-0.7
Schizophrenia (2018)	0.3	0.6	0.7	-0.9	-0.7
Age at First Birth	0.3	0.4	0.4	0.6	-0.6
Smoking Status	0.3	0.7	1.4	1.2	-0.1
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.6	-0.8	0.3
Vitamin and mineral supplements	0.3	0.3	0.7	-0.8	0.0
Supplements: Zinc	0.3	0.3	0.4	0.7	-0.4
Average weekly fortified wine intake	0.3	0.4	0.7	0.8	0.2
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.7	-0.1	-0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.4	-0.7	-0.4
Pain all over the body in last month	0.3	0.3	0.6	-0.0	-0.8
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	0.5	-0.6	-0.7
Fluid intelligence score	0.3	0.6	0.9	0.7	0.9
Time employed in main current job	0.3	0.4	0.8	-0.1	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.6	-0.8	-0.6
Glaucoma (self-reported)	0.3	0.3	0.6	0.7	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.6	0.2	0.8
Neck or shoulder pain in last month	0.3	0.5	0.7	-0.6	-0.8
Arm fat percentage (left)	0.3	1.1	2.0	-0.5	-1.4
Average weekly red wine intake	0.3	0.4	0.7	0.4	-0.9
Osteoporosis (self-reported)	0.3	0.4	0.5	-0.5	0.7
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.7	0.9	-0.0
Average weekly beer plus cider intake	0.3	0.4	0.8	0.0	0.9
Fractured/broken bones in last 5 years	0.3	0.4	0.7	-0.8	-0.1
Pack years of smoking	0.3	0.5	0.9	0.9	0.2
Leg fat mass (left)	0.3	1.3	2.3	-0.5	-1.5
Depression (Nagel 2018)	0.2	0.3	0.5	-0.7	-0.3
Ovarian Cancer	0.2	0.3	0.6	0.1	-0.7
Lupus	0.2	0.3	0.5	-0.7	0.3
Schizophrenia (2014)	0.2	0.3	0.4	-0.6	-0.5
Lung FVC	0.2	0.9	1.8	-0.1	1.4
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.3	0.5	0.6
Pack years adult smoking proportion	0.2	0.3	0.5	0.7	0.1
Body mass index (BMI)	0.2	0.7	0.9	-0.6	-0.9
Past tobacco smoking	0.2	0.4	0.7	0.3	0.9
Forced vital capacity (FVC)	0.2	0.6	1.0	-1.0	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.4	0.6	0.6
Mouth/teeth dental problems	0.2	0.2	0.5	0.7	-0.0
Impedance of arm (right)	0.2	0.8	1.5	0.3	-1.2
Alcohol intake versus 10 years previously	0.2	0.3	0.6	0.2	-0.7
Number of live births	0.2	0.3	0.5	-0.7	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.3	-0.2	-0.6
Depression (self-reported)	0.2	0.2	0.3	-0.3	-0.5
Prospective memory result	0.2	0.3	0.4	-0.3	-0.6
Lung cancer (father)	0.2	0.2	0.3	0.2	0.6
Loud music exposure frequency	0.2	0.3	0.5	0.7	0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.5	0.1	-0.7
Leg fat percentage (right)	0.2	0.6	0.7	-0.8	-0.7
Exposure to tobacco smoke outside home	0.2	0.2	0.4	-0.7	-0.2
Comparative body size at age 10	0.2	0.4	0.7	0.4	0.9
Emphysema/chronic bronchitis	0.2	0.2	0.4	0.6	-0.2
Migraine (self-reported)	0.2	0.2	0.4	-0.6	0.2
Mean time to correctly identify matches	0.2	0.4	0.5	-0.7	-0.6
Pulse rate, automated reading	0.2	0.8	1.0	1.0	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.4	0.6	-0.1
Loneliness, isolation	0.2	0.2	0.5	0.7	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.5	-0.4	0.7
Average weekly champagne plus white wine intake	0.2	0.3	0.4	0.4	0.7
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.4	-0.6	0.1
Risk taking	0.2	0.3	0.6	-0.8	0.3
Age started oral contraceptive pill	0.2	0.3	0.5	0.7	0.1
Ever depressed for a whole week	0.2	0.2	0.4	-0.7	0.1
Myopia	0.2	0.3	0.4	0.6	-0.5
Alcohol drinker status: Previous	0.2	0.2	0.4	-0.6	0.0
Bipolar Disorder (2018)	0.1	0.2	0.5	0.7	0.0
Bipolar Disorder or Schizophrenia	0.1	0.2	0.3	-0.3	-0.5
Alzheimer’s Disease (including proxy)	0.1	0.2	0.4	0.6	-0.1
Major Depression (MDD)	0.1	0.1	0.1	0.2	0.3
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	-0.1	-0.4
Fasting Glucose	0.1	0.1	0.1	0.3	0.1
HbA1C	0.1	0.1	0.1	0.4	0.3
BMI	0.1	0.7	0.8	-0.9	-0.8
Waist Hip Ratio (WHR)	0.1	0.4	0.4	-0.6	-0.6
Neuroticism	0.1	0.2	0.3	-0.1	-0.6
Sensitivity / hurt feelings	0.1	0.1	0.1	-0.4	0.3
Diabetes (mother)	0.1	0.1	0.1	0.1	-0.4
Impedance of leg (right)	0.1	0.6	1.2	-1.1	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.5	-0.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	-0.3	0.4
Supplements: Glucosamine	0.1	0.1	0.2	0.1	-0.4
Impedance of leg (left)	0.1	0.3	0.5	-0.7	0.4
Nervous feelings	0.1	0.2	0.4	-0.7	-0.2
Hearing difficulty/problems with background noise	0.1	0.1	0.2	-0.4	-0.2
Father’s age at death	0.1	0.2	0.3	0.1	0.5
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.3	-0.6	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.4	-0.6	-0.6
Exposure to tobacco smoke at home	0.1	0.1	0.1	-0.4	-0.3
Gout (self-reported)	0.1	0.1	0.1	0.4	-0.1
Number of children fathered	0.1	0.1	0.2	-0.1	0.5
Shortness of breath walking on level ground	0.1	0.2	0.2	0.5	-0.4
Qualifications: College or University degree	0.1	0.3	0.5	0.5	0.7
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	0.4	-0.4
Number of full sisters	0.1	0.1	0.2	-0.4	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.3	0.0	-0.6
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.4	0.2
Commuting to job workplace: Public transport	0.1	0.1	0.1	0.3	0.3
Leg fat percentage (left)	0.1	0.2	0.2	-0.5	-0.5
Blood Red Count	0.0	0.1	0.2	0.2	0.5
Lung FEV1/FVC ratio	0.0	0.2	0.2	-0.4	0.4
Tanning	0.0	0.4	0.5	0.7	0.6
Relative age of first facial hair	0.0	0.0	0.0	0.1	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.0	0.1	-0.2
Noisy workplace	0.0	0.0	0.0	-0.1	0.0
Impedance of arm (left)	0.0	0.1	0.2	0.0	-0.5
Birth weight	0.0	0.1	0.1	-0.3	0.1
Worry too long after embarrassment	0.0	0.1	0.1	-0.3	-0.2
Mood swings	0.0	0.0	0.0	0.1	0.1
Osteoarthritis (self-reported)	0.0	0.0	0.1	-0.3	0.1
Irritability	0.0	0.0	0.0	-0.1	0.0
Commuting to job workplace: Cycle	0.0	0.0	0.0	0.1	0.2
Impedance of whole body	0.0	0.1	0.2	-0.5	-0.2

Hub : Genes

ZNF831

Models

Trait associations