Best TWAS P=7.09e-11 · Best GWAS P=1.62e-08 conditioned to 0.189
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | NCOA1 | 0.11 | 0.02 | enet | 17 | 0.02 | 2.1e-02 | -4.7 | -6.5 | 7.1e-11 | 0.73 | 0.03 | 0.85 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | EFR3B | 0.07 | 0.03 | bslmm | 348 | 0.03 | 3.5e-05 | 4.3 | -5.8 | 8.5e-09 | 0.34 | 0.13 | 0.49 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | ADCY3 | 0.36 | 0.14 | enet | 7 | 0.13 | 8.9e-05 | -5.6 | 5.7 | 1.3e-08 | -0.91 | 0.00 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ADCY3 | 0.09 | 0.02 | enet | 11 | 0.04 | 3.2e-05 | -5.6 | 5.6 | 1.9e-08 | -0.79 | 0.00 | 0.99 | FALSE |