[Hub]/) : Traits : Cardiovascular Disease : ← →

chr2:26,223,547-29,344,127

Best TWAS P=1.09e-12 · Best GWAS P=2.74e-38 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FNDC4	0.13	0.06	lasso	2	0.05	1.1e-03	7.21	-7.1	1.1e-12	0.05	0.00	0.93	TRUE
25	METSIM	Adipose	SLC35F6	0.04	0.01	blup	362	0.02	1.1e-03	3.40	7.0	3.5e-12	0.49	0.11	0.40	TRUE
14	GTEx	Muscle Skeletal	GPN1	0.06	0.02	enet	9	0.02	2.9e-03	4.66	5.6	1.6e-08	0.04	0.27	0.13	TRUE
10	GTEx	Esophagus Gastroesophageal Junction	RP11-373D23.3	0.17	0.01	enet	15	0.04	1.2e-02	-4.25	5.6	1.7e-08	-0.01	0.03	0.64	TRUE
30	The Cancer Genome Atlas	Breast Invasive Carcinoma	GPN1	0.06	0.02	lasso	6	0.02	7.2e-05	5.69	5.6	1.8e-08	0.03	0.01	0.96	TRUE
37	The Cancer Genome Atlas	Thyroid Carcinoma	GCKR	0.18	0.08	enet	5	0.13	1.7e-12	-1.95	-5.3	1.2e-07	-0.01	0.81	0.19	TRUE
7	GTEx	Breast Mammary Tissue (Female)	ABHD1	0.17	0.01	enet	28	0.07	5.3e-03	-0.54	-5.3	1.4e-07	-0.07	0.07	0.05	TRUE
13	GTEx	Esophagus Muscularis	PPM1G	0.06	0.10	lasso	2	0.07	3.7e-05	-5.04	5.2	1.8e-07	-0.03	0.39	0.50	TRUE
38	The Cancer Genome Atlas	Thyroid Carcinoma	KRTCAP3	0.04	0.04	lasso	1	0.03	3.4e-04	-5.21	-5.2	1.9e-07	0.02	0.01	0.92	TRUE
32	The Cancer Genome Atlas	Glioblastoma Multiforme	NRBP1	0.15	0.10	lasso	2	0.10	5.8e-04	-5.13	5.1	3.0e-07	-0.06	0.01	0.48	TRUE
20	GTEx	Testis	AC074117.10	0.14	0.08	lasso	6	0.12	4.5e-06	-5.29	6.8	9.8e-12	-0.03	0.03	0.97	FALSE
16	GTEx	Ovary	AC074117.10	0.16	0.04	enet	9	0.05	2.0e-02	-5.11	6.7	2.5e-11	-0.02	0.06	0.72	FALSE
12	GTEx	Esophagus Muscularis	NRBP1	0.07	0.04	lasso	6	0.04	1.3e-03	-5.13	6.5	7.0e-11	-0.04	0.03	0.94	FALSE
19	GTEx	Testis	NRBP1	0.16	0.09	lasso	3	0.06	1.8e-03	-5.13	6.5	8.4e-11	-0.04	0.02	0.96	FALSE
2	CommonMind	Brain Pre-frontal Cortex	IFT172	0.06	0.09	enet	16	0.09	3.9e-11	-4.94	-6.4	1.7e-10	0.03	0.40	0.60	FALSE
22	GTEx	Vagina	AC074117.10	0.14	0.04	enet	13	0.06	1.4e-02	-5.21	6.2	5.1e-10	0.01	0.10	0.44	FALSE
23	GTEx	Whole Blood	KRTCAP3	0.12	0.05	enet	10	0.05	9.9e-06	-4.95	-6.0	2.6e-09	0.02	0.97	0.02	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	FTH1P3	0.04	0.01	bslmm	280	0.02	2.8e-03	-5.13	5.7	9.6e-09	0.00	0.04	0.72	FALSE
26	NTR	Blood	CGREF1	0.01	0.00	blup	307	0.01	5.7e-03	-4.78	-5.7	1.0e-08	-0.14	0.21	0.02	FALSE
9	GTEx	Cells Transformed fibroblasts	AC074117.10	0.21	0.19	enet	23	0.18	1.6e-13	-5.13	5.7	1.4e-08	-0.01	0.95	0.05	FALSE
33	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC4A1AP	0.02	0.03	lasso	2	0.03	3.7e-04	4.65	-5.7	1.4e-08	-0.03	0.02	0.47	FALSE
36	The Cancer Genome Atlas	Skin Cutaneous Melanoma	SLC4A1AP	0.17	0.05	blup	26	0.08	4.4e-03	5.69	-5.6	1.9e-08	-0.03	0.01	0.47	FALSE
15	GTEx	Nerve Tibial	AC074117.10	0.04	0.05	lasso	2	0.04	7.7e-04	-5.40	5.6	2.5e-08	0.00	0.22	0.33	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	KCNK3	0.24	0.15	lasso	3	0.15	6.5e-19	5.46	-5.5	3.0e-08	-0.35	1.00	0.00	FALSE
18	GTEx	Prostate	AC074117.10	0.14	0.01	lasso	5	0.02	8.8e-02	-5.13	5.5	3.9e-08	-0.01	0.08	0.50	FALSE
17	GTEx	Pituitary	AC074117.10	0.23	0.23	lasso	8	0.29	5.6e-08	-3.94	5.5	4.4e-08	-0.01	0.48	0.39	FALSE
11	GTEx	Esophagus Mucosa	AC074117.10	0.12	0.14	lasso	8	0.14	2.1e-09	-5.13	5.5	4.9e-08	-0.04	0.92	0.08	FALSE
8	GTEx	Cells Transformed fibroblasts	IFT172	0.04	0.04	lasso	2	0.02	8.1e-03	-5.47	-5.4	5.7e-08	0.01	0.17	0.38	FALSE
6	GTEx	Artery Tibial	PPM1G	0.06	0.02	lasso	4	0.03	2.3e-03	-4.26	5.3	1.2e-07	-0.02	0.28	0.16	FALSE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	NRBP1	0.03	0.03	blup	30	0.03	2.2e-04	-5.21	5.3	1.3e-07	-0.06	0.02	0.97	FALSE
5	GTEx	Adrenal Gland	KRTCAP3	0.11	0.16	lasso	4	0.15	4.9e-06	-5.12	-5.3	1.4e-07	0.03	0.43	0.51	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	NRBP1	0.03	0.03	blup	29	0.03	1.2e-06	-5.40	5.3	1.4e-07	-0.03	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	PPM1G	0.04	0.05	lasso	2	0.04	4.9e-04	-5.11	5.2	1.6e-07	-0.02	0.59	0.03	FALSE
21	GTEx	Thyroid	PPM1G	0.06	0.06	lasso	3	0.06	2.2e-05	-5.11	5.2	1.7e-07	-0.03	0.92	0.01	FALSE
4	GTEx	Adipose Visceral Omentum	PPM1G	0.06	0.01	lasso	5	0.01	1.1e-01	-5.11	5.2	2.0e-07	-0.04	0.11	0.28	FALSE
29	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PPM1G	0.03	0.02	blup	31	0.02	8.8e-03	-4.76	5.2	2.1e-07	-0.04	0.02	0.67	FALSE
1	CommonMind	Brain Pre-frontal Cortex	GTF3C2	0.06	0.09	lasso	8	0.08	7.2e-10	-4.25	5.2	2.2e-07	-0.03	0.47	0.53	FALSE
24	METSIM	Adipose	NRBP1	0.06	0.09	lasso	3	0.08	1.6e-12	-5.13	5.2	2.4e-07	-0.07	0.99	0.01	FALSE