[Hub]/) : Traits : Height : ← →

chr3:182,655,858-186,049,228

Best TWAS P=1.88e-24 · Best GWAS P=1.04e-79 conditioned to 4.41e-76

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ECE2	0.24	0.20	bslmm	542	0.19	1.6e-22	6.7	7.3	3.5e-13	0.04	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	KLHL24	0.42	0.60	bslmm	493	0.66	4.5e-107	-6.0	-6.4	2.0e-10	-0.03	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SENP2	0.21	0.18	enet	33	0.19	4.2e-22	-7.1	8.3	7.7e-17	-0.11	1.00	0.00	TRUE
4	GTEx	Adipose Subcutaneous	KLHL24	0.15	0.10	lasso	6	0.10	1.4e-08	-6.2	5.5	4.6e-08	0.02	1.00	0.00	FALSE
5	GTEx	Artery Tibial	PSMD2	0.13	0.09	lasso	5	0.08	1.3e-06	-5.6	5.8	7.3e-09	0.03	0.86	0.04	FALSE
6	GTEx	Artery Tibial	MAP6D1	0.13	0.07	enet	15	0.07	5.1e-06	7.7	-8.2	3.8e-16	-0.03	1.00	0.00	FALSE
7	GTEx	Artery Tibial	YEATS2-AS1	0.07	0.00	lasso	4	0.00	7.5e-01	-4.3	8.6	1.1e-17	0.04	0.10	0.04	FALSE
8	GTEx	Brain Caudate basal ganglia	KLHL24	0.22	0.21	lasso	3	0.19	3.5e-06	-6.2	6.1	9.4e-10	0.02	0.58	0.10	FALSE
9	GTEx	Brain Caudate basal ganglia	MAP6D1	0.14	0.06	lasso	7	0.02	9.9e-02	7.8	-7.1	1.2e-12	0.00	0.17	0.05	FALSE
10	GTEx	Brain Caudate basal ganglia	YEATS2-AS1	0.20	0.05	lasso	3	0.02	1.1e-01	5.3	7.5	5.9e-14	0.09	0.14	0.06	FALSE
11	GTEx	Brain Cerebellar Hemisphere	MAP6D1	0.20	0.03	lasso	6	0.06	1.0e-02	7.7	-9.3	2.1e-20	-0.05	0.21	0.05	FALSE
12	GTEx	Brain Cerebellar Hemisphere	YEATS2-AS1	0.20	0.16	lasso	5	0.16	6.2e-05	7.7	6.4	1.2e-10	0.04	0.56	0.03	FALSE
13	GTEx	Brain Cerebellum	KLHL24	0.52	0.14	enet	26	0.16	1.9e-05	-6.2	6.9	3.9e-12	0.01	0.62	0.24	FALSE
14	GTEx	Brain Cerebellum	MAP6D1	0.38	0.27	enet	38	0.34	1.0e-10	7.8	-10.2	1.9e-24	0.02	0.98	0.00	TRUE
15	GTEx	Brain Cerebellum	YEATS2-AS1	0.48	0.48	lasso	10	0.47	8.0e-16	7.8	7.8	4.9e-15	0.00	1.00	0.00	FALSE
16	GTEx	Brain Cortex	KLHL24	0.21	0.15	lasso	3	0.07	6.1e-03	-6.2	5.3	8.7e-08	0.02	0.34	0.05	FALSE
17	GTEx	Brain Frontal Cortex BA9	KLHL24	0.36	0.23	lasso	6	0.15	9.3e-05	-6.0	5.8	6.4e-09	0.01	0.62	0.07	FALSE
18	GTEx	Brain Nucleus accumbens basal ganglia	MAP6D1	0.19	0.00	enet	24	0.00	2.8e-01	-3.6	-7.0	2.5e-12	-0.07	0.12	0.11	FALSE
19	GTEx	Brain Putamen basal ganglia	ECE2	0.38	0.03	enet	22	0.11	1.4e-03	6.7	5.5	5.1e-08	0.00	0.07	0.24	FALSE
20	GTEx	Breast Mammary Tissue	KLHL24	0.25	0.13	lasso	5	0.11	3.4e-06	-6.2	6.6	5.3e-11	0.02	0.92	0.07	FALSE
21	GTEx	Breast Mammary Tissue	SENP2	0.21	0.00	enet	19	0.05	1.7e-03	-3.4	-8.8	1.7e-18	-0.12	0.06	0.04	FALSE
22	GTEx	Breast Mammary Tissue (Female)	KLHL24	0.25	0.19	lasso	14	0.16	2.3e-05	-7.6	7.8	6.8e-15	-0.01	0.22	0.52	FALSE
23	GTEx	Breast Mammary Tissue (Female)	SENP2	0.29	0.07	enet	27	0.12	1.6e-04	-3.4	-8.9	4.7e-19	-0.17	0.05	0.08	TRUE
24	GTEx	Cells EBV-transformed lymphocytes	PARL	0.25	0.00	lasso	4	-0.01	6.2e-01	-7.6	-8.7	3.6e-18	0.01	0.11	0.08	FALSE
25	GTEx	Cells Transformed fibroblasts	MAP6D1	0.09	0.03	lasso	6	0.03	2.0e-03	7.2	8.1	7.4e-16	-0.01	0.75	0.01	FALSE
26	GTEx	Colon Transverse	YEATS2-AS1	0.24	0.01	lasso	6	0.01	6.7e-02	7.8	5.6	2.6e-08	0.05	0.11	0.16	FALSE
27	GTEx	Esophagus Mucosa	MAP6D1	0.08	0.07	lasso	11	0.07	3.4e-05	7.7	7.7	1.4e-14	0.00	1.00	0.00	FALSE
28	GTEx	Esophagus Muscularis	KLHL24	0.10	0.12	lasso	1	0.09	4.4e-06	-6.2	6.2	6.4e-10	0.03	0.98	0.01	FALSE
29	GTEx	Muscle Skeletal	YEATS2-AS1	0.07	0.08	lasso	7	0.06	1.6e-06	7.8	7.8	5.2e-15	0.00	1.00	0.00	FALSE
30	GTEx	Nerve Tibial	KLHL24	0.08	0.06	lasso	3	0.05	1.5e-04	-6.0	5.9	3.2e-09	0.02	0.67	0.03	FALSE
31	GTEx	Nerve Tibial	YEATS2-AS1	0.08	0.07	lasso	4	0.04	5.3e-04	7.8	7.8	6.7e-15	0.00	0.84	0.01	FALSE
32	GTEx	Pituitary	ECE2	0.52	0.30	lasso	7	0.23	1.5e-06	6.7	5.4	5.5e-08	0.03	0.34	0.32	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	ABCC5	0.12	0.01	lasso	3	0.01	8.4e-02	7.8	7.2	5.8e-13	0.01	0.12	0.06	FALSE
34	GTEx	Skin Not Sun Exposed Suprapubic	KLHL24	0.16	0.01	enet	23	0.00	1.9e-01	-6.2	5.9	3.5e-09	0.04	0.14	0.21	FALSE
35	GTEx	Skin Not Sun Exposed Suprapubic	MAP6D1	0.16	0.08	enet	30	0.06	4.8e-04	7.7	5.5	3.4e-08	-0.01	0.98	0.00	FALSE
36	GTEx	Skin Not Sun Exposed Suprapubic	YEATS2-AS1	0.21	0.21	enet	18	0.21	1.2e-11	7.7	7.3	3.0e-13	0.00	1.00	0.00	FALSE
37	GTEx	Skin Sun Exposed Lower leg	KLHL24	0.09	0.06	lasso	10	0.05	9.5e-05	-6.2	6.0	1.9e-09	0.03	0.84	0.02	FALSE
38	GTEx	Skin Sun Exposed Lower leg	ABCF3	0.13	0.08	lasso	4	0.11	1.6e-09	4.5	5.8	6.2e-09	0.05	0.96	0.03	FALSE
39	GTEx	Skin Sun Exposed Lower leg	PSMD2	0.13	0.14	lasso	4	0.15	1.4e-12	-5.6	5.6	2.5e-08	0.04	1.00	0.00	FALSE
40	GTEx	Skin Sun Exposed Lower leg	MAP6D1	0.07	0.02	lasso	5	0.03	2.7e-03	7.7	6.2	4.4e-10	-0.03	0.40	0.03	FALSE
41	GTEx	Skin Sun Exposed Lower leg	YEATS2-AS1	0.14	0.16	lasso	2	0.16	7.8e-13	7.8	7.8	5.1e-15	0.00	1.00	0.00	FALSE
42	GTEx	Testis	KLHL24	0.17	0.10	lasso	4	0.10	4.0e-05	-6.2	6.2	6.5e-10	0.03	0.86	0.02	FALSE
43	METSIM	Adipose	SENP2	0.06	0.04	lasso	5	0.03	6.2e-06	-7.2	-6.4	1.2e-10	0.01	0.99	0.00	FALSE
44	YFS	Blood	DVL3	0.04	0.00	bslmm	487	0.02	2.7e-07	-3.6	-8.8	1.8e-18	-0.08	0.55	0.01	FALSE
45	YFS	Blood	KLHL24	0.02	0.01	lasso	2	0.01	1.4e-03	-4.5	5.2	2.3e-07	0.05	0.89	0.00	FALSE
46	YFS	Blood	MAP6D1	0.25	0.23	enet	42	0.32	5.3e-107	6.1	-6.0	1.6e-09	0.04	1.00	0.00	FALSE
47	YFS	Blood	SENP2	0.11	0.14	enet	42	0.15	9.8e-47	-7.2	-5.7	9.9e-09	0.10	1.00	0.00	FALSE
48	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	MAP6D1	0.07	0.06	blup	55	0.06	9.4e-04	7.7	8.6	5.4e-18	0.01	0.02	0.97	FALSE
49	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MAP6D1	0.04	0.01	blup	55	0.04	4.0e-05	7.0	8.9	3.7e-19	0.04	0.03	0.96	FALSE
50	The Cancer Genome Atlas	Brain Lower Grade Glioma	ECE2	0.04	0.02	blup	61	0.03	3.5e-04	6.7	5.4	5.9e-08	0.02	0.54	0.02	FALSE
51	The Cancer Genome Atlas	Brain Lower Grade Glioma	KLHL24	0.05	0.05	blup	53	0.05	1.1e-06	-6.0	7.2	4.6e-13	0.02	0.04	0.96	FALSE
52	The Cancer Genome Atlas	Brain Lower Grade Glioma	MAP6D1	0.03	0.04	enet	17	0.05	1.8e-06	6.2	6.3	2.4e-10	0.02	0.02	0.98	FALSE
53	The Cancer Genome Atlas	Lung Adenocarcinoma	PSMD2	0.09	0.02	blup	50	0.05	1.2e-06	-10.5	9.0	1.6e-19	0.06	0.00	0.99	TRUE
54	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PSMD2	0.05	0.00	enet	10	0.01	3.6e-02	6.7	5.5	3.1e-08	-0.02	0.01	0.07	FALSE
55	The Cancer Genome Atlas	Prostate Adenocarcinoma	KLHL24	0.03	0.04	enet	5	0.04	5.1e-05	-6.1	7.2	5.5e-13	0.04	0.03	0.96	FALSE
56	The Cancer Genome Atlas	Testicular Germ Cell Tumors	KLHL24	0.16	0.16	blup	53	0.21	4.3e-08	-6.1	7.1	1.1e-12	0.03	0.03	0.97	FALSE
57	The Cancer Genome Atlas	Testicular Germ Cell Tumors	VWA5B2	0.10	0.04	blup	51	0.04	1.8e-02	4.5	-6.7	1.6e-11	-0.04	0.03	0.33	FALSE
58	The Cancer Genome Atlas	Thyroid Carcinoma	KLHL24	0.10	0.09	blup	53	0.09	1.7e-09	-6.3	7.1	1.6e-12	0.02	0.03	0.97	FALSE
59	The Cancer Genome Atlas	Thyroid Carcinoma	MAP6D1	0.14	0.03	enet	10	0.07	2.6e-07	-6.5	9.2	3.9e-20	0.04	0.06	0.94	FALSE