Best TWAS P=2.58e-14 · Best GWAS P=1.18e-16 conditioned to 7.9e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | TRMT10A | 0.35 | 0.26 | lasso | 9 | 0.26 | 4.8e-12 | 6.0 | 7.2 | 6.5e-13 | 0.88 | 0.02 | 0.98 | TRUE |
| 2 | METSIM | Adipose | TRMT10A | 0.05 | 0.00 | bslmm | 512 | 0.01 | 2.1e-02 | 7.4 | 6.4 | 1.5e-10 | 0.60 | 0.06 | 0.60 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MTTP | 0.02 | 0.01 | blup | 75 | 0.01 | 7.2e-03 | 5.9 | -7.6 | 2.6e-14 | -0.34 | 0.09 | 0.46 | TRUE |