Best TWAS P=7.44e-10 · Best GWAS P=1.25e-21 conditioned to 7.44e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | UBE2D3 | 0.07 | 0.00 | enet | 23 | 0.02 | 3.2e-02 | 2.5 | -5.6 | 2.7e-08 | 0.21 | 0.07 | 0.65 | FALSE |
| 2 | GTEx | Brain Cerebellum | MANBA | 0.18 | 0.03 | enet | 27 | 0.05 | 1.2e-02 | 3.4 | -6.2 | 7.4e-10 | 0.04 | 0.10 | 0.05 | TRUE |
| 3 | GTEx | Pancreas | BDH2 | 0.16 | 0.05 | enet | 10 | 0.10 | 4.9e-05 | 5.4 | 5.3 | 1.1e-07 | -0.12 | 0.91 | 0.06 | FALSE |
| 4 | METSIM | Adipose | SLC39A8 | 0.18 | 0.15 | lasso | 6 | 0.14 | 5.7e-20 | -5.5 | -5.6 | 1.8e-08 | 0.28 | 1.00 | 0.00 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | CENPE | 0.06 | 0.07 | lasso | 15 | 0.06 | 9.4e-09 | 4.5 | 5.4 | 7.9e-08 | -0.07 | 0.88 | 0.12 | FALSE |
| 6 | YFS | Blood | NFKB1 | 0.04 | 0.03 | lasso | 6 | 0.03 | 5.4e-09 | 4.9 | 5.3 | 1.2e-07 | -0.13 | 1.00 | 0.00 | FALSE |
| 7 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CENPE | 0.04 | 0.01 | enet | 10 | 0.02 | 2.6e-03 | 5.2 | -5.9 | 4.2e-09 | 0.12 | 0.01 | 0.86 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BANK1 | 0.04 | 0.02 | blup | 276 | 0.02 | 1.7e-03 | -6.1 | -5.3 | 1.4e-07 | 0.27 | 0.41 | 0.38 | TRUE |