Best TWAS P=4.49e-11 · Best GWAS P=1.65e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | TMEM106B | 0.08 | 0.06 | lasso | 7 | 0.06 | 1.7e-17 | -6.5 | -6.6 | 4.5e-11 | 0.95 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SCIN | 0.05 | 0.00 | blup | 105 | 0.03 | 1.8e-04 | -2.0 | -5.1 | 2.7e-07 | 0.17 | 0.05 | 0.81 | TRUE |