Best TWAS P=7.79e-16 · Best GWAS P=2.71e-23 conditioned to 2.45e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | CPED1 | 0.10 | 0.02 | enet | 26 | 0.04 | 6.2e-04 | -8.9 | -6.3 | 3.2e-10 | 0.55 | 0.18 | 0.67 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | CPED1 | 0.20 | 0.12 | lasso | 5 | 0.16 | 7.6e-12 | -6.2 | -7.7 | 1.0e-14 | 0.79 | 0.36 | 0.64 | FALSE |
3 | NTR | Blood | C7orf58 | 0.04 | 0.02 | lasso | 7 | 0.03 | 9.5e-10 | -5.8 | -5.2 | 1.5e-07 | 0.67 | 0.94 | 0.06 | FALSE |
4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C7orf58 | 0.08 | 0.01 | blup | 158 | 0.01 | 5.1e-02 | -5.2 | -8.1 | 7.8e-16 | 0.72 | 0.03 | 0.45 | TRUE |