[Hub]/) : Traits : Height :

chr7:127,688,625-131,880,252

Best TWAS P=6.62e-10 · Best GWAS P=1.85e-19 conditioned to 2.36e-20

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum IRF5 0.16 0.08 lasso 4 0.08 8.2e-05 -4.8 -5.2 1.6e-07 0.02 0.08 0.81 FALSE
2 GTEx Adipose Visceral Omentum OPN1SW 0.24 0.15 lasso 3 0.14 8.3e-08 -5.1 -5.2 1.9e-07 -0.06 0.10 0.89 FALSE
3 GTEx Cells Transformed fibroblasts CALU 0.25 0.23 enet 13 0.20 1.5e-14 -5.1 -5.4 8.1e-08 -0.03 0.08 0.92 TRUE
4 GTEx Esophagus Mucosa OPN1SW 0.10 0.04 lasso 5 0.03 2.4e-03 -5.1 -5.2 1.6e-07 -0.08 0.09 0.75 FALSE
5 GTEx Esophagus Muscularis IRF5 0.21 0.12 lasso 5 0.11 3.9e-07 -4.8 -5.2 1.8e-07 0.01 0.05 0.94 FALSE
6 GTEx Lung OPN1SW 0.10 0.09 lasso 4 0.11 4.7e-09 -5.1 -5.3 1.2e-07 -0.05 0.09 0.91 FALSE
7 GTEx Nerve Tibial IRF5 0.13 0.09 enet 10 0.07 1.2e-05 -4.8 -5.6 1.7e-08 0.01 0.16 0.81 FALSE
8 GTEx Thyroid MKLN1 0.13 0.01 lasso 4 0.02 1.7e-02 5.9 5.4 5.3e-08 0.01 0.14 0.08 TRUE
9 GTEx Thyroid IRF5 0.14 0.10 enet 6 0.11 1.2e-08 -4.8 -6.2 6.6e-10 0.03 0.04 0.96 TRUE
10 GTEx Thyroid MKLN1-AS2 0.28 0.22 lasso 6 0.25 8.6e-19 4.3 5.3 1.0e-07 -0.01 1.00 0.00 FALSE
11 GTEx Whole Blood IRF5 0.17 0.06 lasso 4 0.09 1.2e-08 5.2 -5.5 3.4e-08 0.01 0.06 0.94 FALSE
12 YFS Blood IRF5 0.65 0.75 lasso 4 0.80 0.0e+00 5.2 5.6 2.0e-08 0.00 0.05 0.95 FALSE
13 YFS Blood KLHDC10 0.29 0.34 lasso 9 0.35 3.4e-119 5.3 -5.7 1.6e-08 -0.03 1.00 0.00 TRUE
14 YFS Blood TNPO3 0.37 0.31 enet 32 0.36 7.4e-125 -4.6 5.2 2.2e-07 -0.03 0.53 0.45 FALSE
15 The Cancer Genome Atlas Colon Adenocarcinoma IRF5 0.29 0.26 enet 6 0.29 3.1e-17 5.4 -5.2 2.5e-07 0.02 0.02 0.98 FALSE
16 The Cancer Genome Atlas Liver Hepatocellular Carcinoma IRF5 0.17 0.09 enet 6 0.15 1.8e-07 5.4 -5.2 1.9e-07 0.00 0.02 0.98 FALSE
17 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IRF5 0.09 0.09 blup 30 0.13 3.1e-14 5.4 -5.9 3.5e-09 0.02 0.02 0.98 FALSE
18 The Cancer Genome Atlas Pancreatic Adenocarcinoma IRF5 0.09 0.10 lasso 3 0.08 4.6e-04 5.4 -5.7 1.4e-08 0.02 0.02 0.76 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma IRF5 0.23 0.26 lasso 3 0.26 3.6e-27 5.4 -5.2 1.7e-07 0.02 0.02 0.98 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma IRF5 0.22 0.21 enet 9 0.26 4.6e-25 5.4 -5.4 8.5e-08 0.01 0.02 0.98 FALSE
21 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma IRF5 0.27 0.16 blup 30 0.22 9.7e-07 5.4 -5.8 8.1e-09 0.01 0.02 0.97 FALSE