Best TWAS P=7.9e-11 · Best GWAS P=3.58e-12 conditioned to 0.00468
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | AL137059.1 | 0.11 | 0.01 | lasso | 6 | 0.02 | 5.0e-03 | -4.2 | -6.5 | 7.9e-11 | -0.51 | 0.04 | 0.78 | TRUE |
| 2 | GTEx | Testis | MTIF3 | 0.45 | 0.28 | lasso | 11 | 0.25 | 1.8e-11 | 5.1 | -6.0 | 1.8e-09 | -0.78 | 0.29 | 0.71 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MTIF3 | 0.04 | 0.01 | blup | 74 | 0.01 | 8.3e-03 | 5.1 | 6.4 | 1.8e-10 | 0.71 | 0.04 | 0.36 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RASL11A | 0.04 | 0.04 | blup | 45 | 0.05 | 4.9e-06 | 4.5 | 5.3 | 1.2e-07 | 0.25 | 0.00 | 0.96 | TRUE |