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chr13:36,177,136-38,188,938

Best TWAS P=4.53e-13 · Best GWAS P=7.55e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SMAD9	0.25	0.16	lasso	8	0.16	1.2e-18	5.9	6.0	2.3e-09	0.01	0.46	0.54	FALSE
2	GTEx	Liver	SPG20	0.24	0.04	lasso	4	0.05	1.6e-02	-4.9	5.4	5.7e-08	-0.67	0.06	0.56	FALSE
3	GTEx	Nerve Tibial	SMAD9	0.16	0.11	enet	22	0.15	1.0e-10	6.0	6.5	8.9e-11	-0.09	0.43	0.55	FALSE
4	GTEx	Pancreas	SPG20	0.27	0.11	lasso	4	0.06	1.3e-03	-6.8	7.2	4.5e-13	-0.96	0.01	0.98	TRUE
5	GTEx	Whole Blood	SPG20	0.09	0.02	enet	30	0.00	1.5e-01	-6.6	-6.7	2.0e-11	0.77	0.02	0.96	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	C13orf38	0.04	0.02	lasso	4	0.03	2.0e-07	-6.0	-6.0	2.5e-09	0.82	0.01	0.99	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	SMAD9	0.06	0.02	enet	9	0.03	5.2e-07	5.9	6.8	8.4e-12	0.03	0.00	1.00	TRUE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	SOHLH2	0.13	0.19	lasso	13	0.22	1.7e-43	-4.9	-6.4	1.8e-10	0.76	0.97	0.03	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	SPG20	0.02	0.01	enet	7	0.01	2.0e-02	3.4	-5.7	1.0e-08	0.65	0.05	0.46	FALSE
10	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	SOHLH2	0.11	0.14	enet	19	0.11	5.7e-06	-4.8	-6.2	7.7e-10	0.64	0.17	0.82	FALSE
11	The Cancer Genome Atlas	Glioblastoma Multiforme	SOHLH2	0.35	0.28	blup	105	0.27	8.3e-09	-4.9	-6.5	8.0e-11	0.68	0.57	0.42	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SOHLH2	0.11	0.18	enet	12	0.19	2.0e-21	-4.8	-6.2	4.6e-10	0.73	0.96	0.04	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SOHLH2	0.27	0.29	enet	22	0.30	8.4e-18	-4.9	-5.9	3.9e-09	0.59	0.99	0.01	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	C13orf38	0.06	0.04	lasso	2	0.04	2.2e-05	-6.0	-6.0	2.0e-09	0.89	0.01	0.97	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	SMAD9	0.08	0.03	enet	6	0.05	2.9e-06	5.9	6.7	2.5e-11	0.04	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	SOHLH2	0.25	0.41	enet	20	0.42	4.7e-52	-4.8	-6.0	1.5e-09	0.68	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	C13orf38	0.08	0.03	blup	66	0.06	4.9e-08	2.5	-5.6	1.7e-08	0.69	0.06	0.93	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	SOHLH2	0.10	0.15	lasso	3	0.16	5.8e-18	-4.8	-5.7	1.5e-08	0.60	0.99	0.01	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SOHLH2	0.14	0.10	lasso	4	0.15	3.9e-10	-4.8	-5.7	1.1e-08	0.72	0.24	0.76	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SOHLH2	0.09	0.14	lasso	2	0.11	2.4e-05	-4.8	-5.1	2.8e-07	0.49	0.45	0.24	FALSE
21	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C13orf38	0.11	0.02	blup	66	0.07	1.1e-03	-6.7	-6.8	1.2e-11	0.83	0.01	0.96	FALSE
22	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SOHLH2	0.23	0.15	blup	105	0.21	5.8e-09	-4.9	-6.1	8.5e-10	0.74	0.05	0.95	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	C13orf38	0.15	0.17	lasso	3	0.17	1.8e-17	-6.6	-6.2	5.5e-10	0.91	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	SOHLH2	0.24	0.33	lasso	10	0.36	2.6e-39	-6.6	-6.7	2.1e-11	0.85	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	SPG20	0.04	0.00	blup	74	0.02	3.0e-03	-4.8	6.6	3.6e-11	-0.79	0.02	0.45	FALSE
26	The Cancer Genome Atlas	Rectum Adenocarcinoma	SOHLH2	0.16	0.05	blup	105	0.03	6.3e-02	4.4	-6.4	1.8e-10	0.66	0.03	0.52	FALSE
27	The Cancer Genome Atlas	Rectum Adenocarcinoma	SPG20	0.17	0.15	lasso	8	0.13	6.7e-04	-6.0	6.3	3.8e-10	-0.92	0.02	0.88	FALSE
28	The Cancer Genome Atlas	Soft Tissue Sarcoma	SOHLH2	0.16	0.08	enet	21	0.15	1.7e-09	-4.8	-5.6	1.7e-08	0.56	0.16	0.83	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	C13orf38	0.10	0.07	lasso	4	0.10	3.9e-10	-6.5	-6.7	2.4e-11	0.84	0.02	0.98	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	SOHLH2	0.32	0.39	enet	33	0.43	6.0e-46	-4.9	-6.1	1.2e-09	0.72	1.00	0.00	FALSE