Best TWAS P=3.32e-11 · Best GWAS P=5.38e-27 conditioned to 5.55e-25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | NKX2-8 | 0.04 | 0.03 | blup | 67 | 0.02 | 1.0e-03 | -4.7 | 6.2 | 5.4e-10 | 0.04 | 0.23 | 0.38 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC25A21 | 0.11 | 0.02 | blup | 345 | 0.05 | 8.8e-04 | -3.4 | -6.6 | 3.3e-11 | -0.04 | 0.19 | 0.03 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | NKX2-8 | 0.03 | 0.02 | blup | 67 | 0.02 | 3.3e-03 | -4.9 | 6.0 | 2.3e-09 | 0.08 | 0.08 | 0.44 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC25A21 | 0.15 | 0.12 | blup | 353 | 0.11 | 5.2e-11 | -3.6 | -5.7 | 1.5e-08 | -0.08 | 1.00 | 0.00 | FALSE |