Best TWAS P=1.81e-17 · Best GWAS P=1.47e-19 conditioned to 0.359
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | NFKBIA | 0.26 | 0.09 | lasso | 10 | 0.12 | 3.4e-36 | -9.0 | -8.5 | 1.8e-17 | 0.92 | 0 | 1.00 | TRUE |
| 2 | YFS | Blood | NFKBIA | 0.24 | 0.11 | enet | 33 | 0.17 | 3.5e-53 | -9.0 | -6.7 | 2.1e-11 | 0.72 | 0 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | FAM177A1 | 0.08 | 0.00 | blup | 54 | 0.02 | 1.0e-02 | -4.1 | 5.7 | 1.2e-08 | -0.31 | 0 | 0.11 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | SRP54 | 0.07 | 0.00 | blup | 58 | 0.03 | 1.3e-03 | 3.6 | -5.4 | 7.3e-08 | 0.17 | 0 | 0.04 | TRUE |