Best TWAS P=2.81e-08 · Best GWAS P=1.63e-26 conditioned to 7.2e-20
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | VTI1B | 0.18 | 0.03 | enet | 27 | 0.09 | 1.1e-07 | -4.59 | -5.5 | 2.8e-08 | 0.46 | 0.62 | 0.04 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | VTI1B | 0.02 | 0.00 | blup | 39 | 0.01 | 7.3e-03 | -4.33 | -5.2 | 2.1e-07 | 0.46 | 0.00 | 0.23 | FALSE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | RAD51L1 | 0.04 | 0.00 | blup | 471 | 0.00 | 9.9e-02 | -0.93 | -5.2 | 2.0e-07 | 0.61 | 0.07 | 0.26 | FALSE |