TWAS hub - VTI1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1140	0.0430	1.2e-03	0.003	NA	0.035	NA	0.007	1.8e-01	NA	7.5e-04	NA	7.4e-02
2	GTEx	Cells EBV-transformed lymphocytes	0.2160	0.0660	4.7e-05	0.248	NA	0.209	NA	0.243	1.2e-08	NA	2.2e-07	NA	1.8e-08
3	GTEx	Muscle Skeletal	0.0612	0.0277	5.1e-03	0.038	NA	0.045	NA	0.031	1.3e-04	NA	3.1e-05	NA	4.8e-04
4	GTEx	Nerve Tibial	0.1535	0.0535	1.3e-03	0.023	NA	0.036	NA	0.035	9.3e-03	NA	1.4e-03	NA	1.5e-03
5	GTEx	Thyroid	0.1830	0.0500	2.2e-06	0.026	NA	0.094	NA	0.065	4.2e-03	NA	1.1e-07	NA	1.1e-05
6	TCGA	Breast Invasive Carcinoma	0.0168	0.0097	5.9e-03	0.005	0.008	0.003	NA	0.002	3.1e-02	0.00730	6.2e-02	NA	9.5e-02
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0272	0.0156	1.4e-03	0.011	0.028	0.021	NA	0.022	2.0e-02	0.00033	1.8e-03	NA	1.5e-03
8	TCGA	Lung Adenocarcinoma	0.0268	0.0145	1.7e-04	0.016	0.025	0.022	NA	0.021	4.3e-03	0.00054	1.2e-03	NA	1.6e-03
9	TCGA	Pheochromocytoma and Paraganglioma	0.1920	0.1020	4.8e-04	0.023	0.091	0.133	NA	0.094	4.2e-02	0.00018	6.0e-06	NA	1.5e-04
10	TCGA	Stomach Adenocarcinoma	0.0440	0.0260	2.5e-03	0.056	0.024	0.010	NA	0.040	6.9e-05	0.00660	6.0e-02	NA	7.1e-04
11	TCGA	Thyroid Carcinoma	0.0330	0.0190	1.1e-03	0.005	0.025	0.008	NA	0.012	9.6e-02	0.00150	5.1e-02	NA	2.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Frequency of depressed mood in last 2 weeks	4.5	6.3	13.6	0.8	3.0	1.2	3.7	2.2	2.2	2.9	2.9	0.6	3.1	2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	4.3	5.7	17.9	1.3	2.8	1.7	4.2	1.4	1.6	2.3	2.6	1.5	3.1	2.1
High blood pressure (mother)	3.9	5.4	13.0	-0.8	-2.8	-2.3	-2.0	-3.6	-2.0	-2.3	-2.5	0.5	-2.5	-2.6
Stomach or abdominal pain in last month	3.6	4.4	7.0	1.5	2.0	1.6	1.9	2.2	2.1	2.7	2.4	1.7	2.3	2.4
Reason for reducing amount of alcohol drunk: Health precaution	3.4	4.0	7.5	1.4	2.2	1.4	2.2	1.4	1.7	2.4	2.5	1.1	2.7	2.0
Tinnitus: Yes, now most or all of the time	3.3	3.9	8.5	-1.2	-1.8	-2.0	-1.9	-2.9	-1.5	-2.5	-2.2	-0.2	-1.3	-2.6
Illnesses of siblings: Diabetes	3.1	3.8	9.7	1.5	2.2	3.1	1.3	1.2	0.1	2.5	2.5	-0.6	1.5	2.6
Depression (Nagel 2018)	3.0	4.5	13.5	1.0	2.7	1.2	3.7	0.7	0.7	2.0	2.6	1.3	3.2	1.6
Medication: Ibuprofen	2.9	3.5	7.6	1.7	1.7	1.1	1.6	1.1	2.1	2.8	2.2	1.1	1.9	2.5
Commuting to job workplace: Walk	2.9	3.2	6.3	-0.9	-1.9	-2.5	-1.4	-0.7	-0.1	-2.3	-2.5	1.8	-1.7	-2.0
Myopia	2.9	4.2	7.0	-2.3	-2.2	-1.6	-1.1	-1.9	-1.9	-2.5	-2.6	-0.6	-2.3	-2.4
Intelligence (Savage-Jansen 2018)	2.8	8.6	14.9	-3.1	-2.4	-3.2	-2.1	-2.9	-2.9	-3.9	-3.2	-1.7	-2.2	-3.7
Bilateral oophorectomy (both ovaries removed)	2.8	3.2	6.7	-1.7	-1.9	-1.2	-2.6	-0.9	-1.7	-1.9	-2.1	-1.1	-2.3	-1.6
Hand grip strength (right)	2.6	7.1	12.2	-1.9	-2.4	-2.6	-3.5	-2.5	-3.0	-3.0	-2.7	-1.6	-2.7	-2.9
Supplements: Fish oil (including cod liver oil)	2.6	3.4	5.9	1.7	1.9	0.8	2.4	1.4	1.8	2.1	2.3	0.5	2.4	1.8
Prospective memory result	2.4	2.9	7.2	0.8	1.7	1.3	2.1	1.3	0.7	2.3	2.7	-0.0	2.2	1.7
Past tobacco smoking	2.3	4.2	10.8	-1.4	-2.3	-1.2	-3.3	-0.4	-1.5	-2.2	-2.1	-2.0	-3.0	-1.6
Depression (self-reported)	2.3	2.8	5.6	0.9	1.7	1.3	1.9	1.5	1.1	2.2	2.4	0.3	1.5	2.2
Handedness (chirality/laterality): Left-handed	2.3	2.8	8.8	3.0	2.1	1.2	1.6	0.3	0.8	1.6	1.9	0.1	2.0	1.6
Pain type(s) experienced in last month: Hip pain	2.3	2.9	5.7	1.6	1.5	1.9	1.8	0.6	1.1	2.4	1.9	1.4	1.2	2.3
Unable to work because of sickness or disability	2.3	2.9	8.5	0.4	1.5	0.7	2.9	0.7	1.8	2.0	1.9	1.4	2.2	1.4
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	6.1	1.1	1.6	1.0	1.7	0.6	1.7	2.5	2.1	1.2	1.9	2.0
Commuting to job workplace: Car/motor vehicle	2.1	2.4	4.6	0.8	1.8	2.1	0.5	1.1	1.0	1.9	2.1	-0.2	1.5	2.0
Nervous feelings	2.0	3.7	7.1	0.5	2.5	1.5	2.7	2.2	1.7	1.7	1.9	0.8	2.6	1.7
Happiness	2.0	2.5	8.3	2.8	1.1	0.5	2.9	0.7	1.7	1.1	1.0	1.2	1.3	1.1
Loneliness, isolation	2.0	2.8	7.7	0.8	2.3	0.9	2.5	0.1	0.9	1.6	2.0	1.1	2.8	1.2
Fed-up feelings	1.9	3.5	7.8	0.5	1.7	1.8	2.8	1.5	1.9	2.2	2.0	1.3	1.7	2.1
Lung cancer (father)	1.9	2.2	4.0	1.5	2.0	0.4	1.9	1.3	0.5	1.6	1.9	-0.3	1.9	1.5
Severe depression (siblings)	1.8	2.0	5.8	0.1	1.9	2.4	-0.4	0.4	-1.5	1.5	1.7	-1.2	1.4	1.3
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	9.9	0.2	1.9	1.0	3.1	1.0	1.1	1.7	1.9	-0.4	2.1	1.6
Falls in the last year	1.8	2.4	4.4	1.2	1.8	1.5	2.1	1.1	1.1	1.7	1.8	1.0	1.8	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.7	5.8	1.7	1.8	1.8	2.4	1.4	0.7	1.6	1.9	-0.6	1.7	1.7
Breast cancer (self-reported)	1.8	2.2	6.7	0.4	0.9	0.1	1.6	2.6	2.4	1.2	1.2	1.3	1.1	1.4
Alcohol intake versus 10 years previously	1.7	2.6	9.0	0.6	0.4	0.4	0.4	1.8	3.0	1.5	1.1	3.0	0.9	1.4
Length of working week for main job	1.7	1.9	9.8	-0.7	0.9	2.0	-0.2	-1.9	-3.1	0.2	0.5	-1.1	-0.0	0.1
Medication: Lansoprazole	1.6	1.8	4.2	0.6	1.1	1.8	0.9	2.0	1.2	1.6	1.6	0.0	0.9	1.7
Angina (self-reported)	1.6	2.0	4.8	-1.3	2.2	1.8	1.5	0.2	0.5	1.3	1.5	-0.3	1.9	1.6
Migraine (self-reported)	1.6	2.0	4.3	-0.8	-0.9	-1.3	-1.2	-2.1	-2.1	-1.7	-1.0	-0.7	-0.6	-2.0
Mood swings	1.6	2.9	5.2	0.1	2.1	1.3	1.7	1.5	1.3	2.1	2.3	0.3	2.2	2.0
Friendships satisfaction	1.6	2.0	8.5	2.9	0.4	-0.2	2.6	1.0	2.2	0.3	0.4	0.2	0.7	0.6
Medication for hormone replacement therapy	1.5	1.7	3.2	1.0	-1.5	-1.8	-1.4	-0.6	-0.3	-1.6	-1.8	-0.9	-1.3	-1.4
Had major operations	1.5	1.7	5.4	1.1	1.7	1.0	2.3	0.7	0.1	1.3	1.4	0.5	1.7	1.1
Smoking status: Previous	1.5	2.3	5.8	1.1	1.4	0.5	2.4	-0.0	1.6	1.3	1.0	2.4	2.2	0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.0	7.0	-1.0	-2.3	-1.2	-2.1	-1.8	-1.5	-1.6	-1.8	-0.6	-2.7	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.2	1.4	0.9	-0.1	1.8	1.7	1.3	1.3	1.3	-0.4	0.7	1.5
Illnesses of father: High blood pressure	1.5	1.8	2.6	-1.2	-1.5	-1.4	-1.3	-1.6	-1.4	-1.0	-1.1	-1.4	-1.5	-1.1
Arm predicted mass (left)	1.5	7.5	13.9	-2.5	-3.2	-2.8	-2.3	-3.7	-1.8	-2.8	-3.0	0.6	-2.7	-3.2
Angina	1.4	1.8	4.2	-1.5	2.0	1.6	1.5	0.2	0.6	1.1	1.3	-0.2	1.8	1.4
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	3.7	0.3	1.9	1.6	0.9	0.3	0.4	1.5	1.9	0.0	1.9	1.4
Emphysema/chronic bronchitis	1.4	1.5	8.5	2.9	0.4	1.3	1.7	-1.1	0.7	0.6	0.1	1.0	0.3	0.6
Long-standing illness, disability or infirmity	1.4	2.1	6.5	0.9	1.1	1.1	2.5	0.9	1.1	1.8	1.9	0.1	1.2	1.7
Arm fat-free mass (left)	1.4	6.9	12.9	-2.6	-3.1	-2.8	-2.4	-3.6	-1.6	-2.6	-2.8	0.7	-2.5	-3.0
Depressed Affect (Nagel 2018)	1.3	2.8	9.1	0.1	2.0	0.3	3.0	1.1	1.7	1.4	1.8	0.8	2.5	1.2
Blood Platelet Count	1.3	15.1	83.0	-1.6	-0.5	2.1	-1.5	-9.1	-7.9	-1.4	-0.7	-0.4	-0.9	-2.9
Illnesses of siblings	1.3	1.9	4.9	-0.9	-1.2	-2.2	-0.3	-0.5	-0.6	-2.0	-1.7	-1.2	-0.9	-1.9
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	9.0	0.5	1.5	1.3	3.0	0.6	0.4	1.4	1.7	0.7	1.6	1.2
Qualifications: A levels/AS levels or equivalent	1.3	2.8	6.1	-0.4	-1.4	-0.7	-1.7	-2.3	-2.5	-2.0	-1.7	-0.7	-1.6	-2.0
Medication: Ventolin 100micrograms inhaler	1.3	1.7	5.1	0.5	1.0	2.3	0.9	0.9	1.2	1.6	1.2	1.4	0.7	1.6
Number of self-reported non-cancer illnesses	1.3	2.3	6.6	0.5	0.9	0.3	2.6	1.1	2.4	1.6	1.5	1.2	1.5	1.4
Commuting to job workplace: Public transport	1.3	1.5	3.0	-0.7	-1.3	-1.2	-1.2	-1.3	-1.0	-1.3	-1.7	0.3	-1.3	-1.5
Basal cell carcinoma (self-reported)	1.3	1.5	2.8	1.5	1.5	0.9	1.7	-0.3	0.4	1.5	1.4	0.3	1.2	1.4
Neuroticism (Nagel 2018)	1.2	2.9	9.3	0.1	2.2	-0.1	3.0	1.1	1.5	1.1	1.6	1.0	3.0	0.8
Medication: Atenolol	1.2	1.5	7.1	-0.5	0.8	0.6	0.2	-1.7	-2.2	-0.1	0.3	-2.7	0.2	-0.1
Sitting height	1.2	8.8	15.9	-1.0	-2.7	-2.7	-3.2	-4.0	-3.7	-3.3	-3.2	-0.5	-2.6	-3.7
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	4.3	-0.3	-1.5	-1.7	-0.8	-2.1	-0.5	-1.3	-1.4	-0.2	-1.1	-1.4
Breast Cancer	1.1	2.7	12.7	-0.8	-0.2	1.4	-1.0	-3.6	-3.2	0.1	0.4	-1.6	-0.7	-0.5
Allergy or Eczema	1.1	2.8	4.9	-0.8	-1.8	-1.4	-2.0	-0.6	-1.0	-2.2	-2.2	-1.9	-1.8	-2.0
Type 2 Diabetes (T2D) (2018)	1.1	2.0	5.9	0.5	1.1	2.4	0.1	1.8	0.7	1.8	1.8	-0.0	0.8	1.9
Medication: Metformin	1.1	1.5	3.9	-0.1	1.2	2.0	0.3	1.6	0.9	1.5	1.6	-0.5	0.8	1.7
Trunk fat-free mass	1.1	6.1	14.6	-1.7	-2.9	-2.6	-1.9	-3.8	-2.0	-2.5	-2.5	0.7	-2.4	-2.9
Trunk predicted mass	1.1	6.3	14.4	-1.9	-2.9	-2.7	-2.0	-3.8	-2.0	-2.5	-2.6	0.7	-2.4	-3.0
Hair/balding pattern: Pattern 4	1.1	2.7	10.5	1.3	1.0	0.4	1.1	3.2	2.9	0.7	0.8	1.6	1.3	1.2
Arm fat-free mass (right)	1.1	5.4	11.8	-2.2	-2.6	-2.5	-1.9	-3.4	-1.9	-2.3	-2.4	0.2	-2.1	-2.7
Overall health rating	1.1	2.3	6.3	0.3	1.0	1.6	2.5	0.2	0.9	2.1	1.8	1.9	1.3	1.4
Back pain experienced in last month	1.1	1.6	3.9	0.4	0.3	1.2	1.2	1.1	2.0	1.5	0.9	1.8	0.3	1.6
Whole body water mass	1.1	6.1	13.8	-2.1	-2.8	-2.6	-1.8	-3.7	-1.8	-2.6	-2.7	0.5	-2.2	-3.0
Ever depressed for a whole week	1.1	1.4	2.8	-0.6	-1.7	-1.1	-1.5	-1.4	-0.2	-0.8	-1.4	0.7	-1.3	-1.2
Alzheimer’s Disease (in mother)	1.0	1.1	3.2	1.8	1.0	0.6	1.4	1.0	0.8	0.6	0.9	-1.1	1.0	0.8
Neuroticism	1.0	2.3	5.4	0.3	1.7	0.2	2.3	0.7	2.0	1.3	1.4	1.6	2.2	1.1
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	4.3	1.1	1.4	0.7	1.1	1.2	-0.6	0.4	1.1	-2.1	1.7	0.3
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	7.7	-0.7	-1.1	-2.1	-2.4	-2.6	-2.8	-1.9	-1.4	-0.8	-0.8	-2.2
Mouth/teeth dental problems: Dentures	1.0	1.6	5.5	0.9	1.8	0.6	2.3	-0.1	-0.1	1.1	1.6	-0.2	1.8	0.9
Pulse wave Arterial Stiffness index	1.0	1.1	5.9	-2.4	-0.9	-0.7	-0.9	-0.4	-0.6	-0.7	-0.5	-1.3	-1.2	-0.5
Arm predicted mass (right)	1.0	5.1	11.5	-2.2	-2.5	-2.5	-1.9	-3.4	-1.7	-2.2	-2.3	0.3	-2.0	-2.6
Age at last live birth	1.0	1.5	3.8	-0.9	-1.1	-1.9	-0.4	-1.9	-0.5	-1.3	-1.6	-0.4	-0.8	-1.4
Leg pain on walking	1.0	1.3	3.2	0.4	-1.3	-0.4	-1.5	-0.8	-1.7	-0.7	-0.8	-1.3	-1.8	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	4.2	0.8	0.8	2.0	0.6	-0.2	-1.6	0.8	0.9	-1.4	-0.3	1.0
Guilty feelings	1.0	1.5	3.1	0.8	1.0	0.6	1.0	0.9	1.5	1.8	1.3	1.3	1.2	1.6
Ever smoked	1.0	1.8	5.7	0.3	1.5	0.5	2.4	-0.5	0.6	1.6	1.5	1.0	2.1	1.0
Basal metabolic rate	1.0	5.3	10.5	-2.1	-2.7	-2.5	-1.6	-3.2	-1.5	-2.4	-2.6	0.5	-2.2	-2.8
Average weekly beer plus cider intake	1.0	1.4	6.4	-0.1	1.0	2.5	1.2	0.0	-1.2	0.9	1.1	-1.6	0.3	0.9
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.8	-0.2	-0.1	-0.9	1.9	-1.7	-1.1	-1.5	-1.0	-0.8	0.1	-1.4
Bipolar Disorder (2018)	0.9	1.5	5.0	2.2	0.9	-0.1	1.4	-0.0	0.9	1.0	1.2	1.4	1.7	0.6
Crohns Disease (2012)	0.9	1.5	2.7	0.5	-1.5	-0.9	-1.6	-1.7	-0.4	-1.2	-1.5	0.4	-1.5	-1.1
Medication: Co-codamol	0.9	1.0	4.0	0.5	0.8	0.4	1.4	2.0	1.1	0.1	0.3	-1.2	0.7	0.6
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	1.7	-1.1	-0.7	-0.2	-1.2	-0.3	-0.8	-1.3	-1.3	-1.1	-0.9	-1.0
Pain all over the body in last month	0.9	0.9	3.0	-1.7	1.0	0.4	1.3	-0.2	-1.3	-0.2	0.3	-1.4	0.8	-0.3
Weight	0.9	4.4	8.2	-1.9	-2.9	-2.5	-1.0	-2.2	-0.5	-2.3	-2.6	0.7	-2.2	-2.5
Hair/balding pattern: Pattern 3	0.9	1.3	3.7	-0.9	-1.4	-0.6	-1.9	-1.2	-1.1	-1.0	-0.9	-0.2	-1.4	-1.1
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	4.0	-1.9	-0.7	-0.2	-2.0	-1.8	-1.1	-0.8	-0.9	-0.3	-0.7	-0.9
Chest pain or discomfort	0.9	1.2	2.8	0.4	1.7	1.1	1.4	1.0	0.9	0.5	1.0	-1.1	1.5	0.9
Whole body fat-free mass	0.9	5.3	12.5	-2.0	-2.6	-2.5	-1.6	-3.5	-1.6	-2.4	-2.5	0.6	-2.0	-2.8
Medication for cholesterol	0.9	1.4	3.5	-0.3	1.1	1.7	-0.3	1.5	0.4	1.7	1.4	-0.4	0.4	1.9
Mineral and other dietary supplements	0.9	1.2	2.2	-0.9	-0.9	-0.4	-0.8	-1.5	-1.5	-1.2	-1.2	-0.7	-0.9	-1.3
Illnesses of father: None of the above (group 1)	0.9	1.1	2.7	0.7	1.2	1.2	1.1	1.6	0.9	1.0	0.9	0.3	0.9	1.1
Irritability	0.9	1.5	3.6	-0.2	1.4	0.5	1.5	1.5	1.9	0.7	0.8	1.1	1.7	0.8
Rheumatoid Arthritis	0.8	1.0	3.6	0.5	0.2	0.9	0.2	1.8	1.9	0.9	0.7	1.1	0.4	1.1
Hand grip strength (left)	0.8	2.0	6.0	-0.2	-1.0	-0.7	-2.4	-1.8	-1.8	-1.3	-1.2	-0.7	-1.7	-1.1
Average weekly fortified wine intake	0.8	0.9	2.3	-1.2	-0.7	-1.1	-0.9	-0.8	-0.9	-1.3	-1.1	-0.1	-0.2	-1.5
Relative age voice broke	0.8	1.2	2.6	-0.4	-1.5	-0.8	-1.0	-1.6	-0.6	-1.1	-1.3	-0.4	-1.2	-1.3
Chronic bronchitis/emphysema (father)	0.8	1.0	5.3	1.6	-0.7	0.0	0.3	-1.2	-0.1	-0.3	-0.6	2.3	-0.6	-0.5
Blood clot in the leg (DVT)	0.8	1.0	2.9	1.7	1.0	1.7	0.3	0.5	0.3	1.0	1.1	0.5	0.8	1.1
Birth weight	0.8	1.7	4.4	-0.9	-1.9	-0.9	-1.3	-1.1	-0.4	-1.2	-1.5	1.3	-2.1	-1.0
Exposure to tobacco smoke outside home	0.8	1.0	2.4	-1.5	1.0	1.6	0.0	-0.2	-0.8	0.9	1.1	-1.3	0.4	1.1
Pulse wave peak to peak time	0.8	0.9	6.2	2.5	0.7	0.5	0.7	-0.0	0.2	0.4	0.3	1.2	0.9	0.1
Medication: Seretide 50 evohaler	0.8	0.9	4.5	1.2	-0.0	-0.0	1.1	0.4	2.1	0.3	0.0	1.4	0.6	0.3
Pulse rate, automated reading	0.8	2.7	4.8	-1.5	-2.1	-1.8	-0.7	-1.0	-0.7	-2.2	-2.2	-0.2	-1.9	-2.2
Leg fat-free mass (right)	0.8	4.2	9.0	-2.0	-2.3	-2.2	-1.2	-3.0	-1.3	-2.2	-2.4	0.3	-1.7	-2.6
Diabetes diagnosed by doctor	0.8	1.4	4.9	-1.0	0.9	2.2	0.1	1.6	0.4	1.0	1.1	-1.2	0.4	1.4
Qualifications: nursing, teaching	0.8	1.3	5.4	0.3	-0.5	-1.1	-0.2	-2.3	-0.8	-0.9	-0.8	1.8	-0.0	-1.3
Leg predicted mass (right)	0.8	4.2	9.1	-2.0	-2.2	-2.2	-1.2	-3.0	-1.3	-2.2	-2.4	0.2	-1.7	-2.6
Eye problems/disorders: Glaucoma	0.8	1.0	2.3	0.2	1.4	1.3	-0.1	-0.5	-1.1	1.1	1.5	-0.6	0.7	1.2
Pain experienced in last month	0.8	1.3	3.5	-0.7	-0.6	-1.1	-1.5	-0.8	-1.5	-1.1	-0.8	-1.9	-0.8	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	3.4	1.8	1.0	1.7	0.1	0.3	0.0	0.9	1.0	0.1	0.7	1.0
Heart disease (siblings)	0.8	1.0	4.3	-2.1	-1.5	-0.6	-0.6	-0.1	0.4	-0.6	-1.0	0.5	-1.3	-0.6
Worry (Nagel 2018)	0.7	1.4	6.4	0.6	1.4	-0.7	2.5	-0.1	0.3	-0.2	0.4	0.5	2.2	-0.6
Verbal and Numeric Reasoning (VNR)	0.7	1.7	3.6	-1.5	-0.8	-1.4	-1.2	-1.2	-1.1	-1.9	-1.5	-1.0	-0.9	-1.6
Body Mass Index (BMI) (2010)	0.7	1.0	2.4	-1.0	-1.2	-1.5	-1.3	0.2	1.1	-0.7	-1.1	0.1	-1.1	-0.4
Coronary Artery Disease (CAD)	0.7	0.8	3.4	-1.3	-0.0	0.6	0.3	-1.9	-1.7	-0.2	-0.2	0.2	-0.1	-0.7
Fasting Glucose	0.7	0.9	2.9	-0.5	-0.7	-0.3	-1.7	1.4	1.1	0.5	-0.1	-1.0	-0.9	0.7
Blood Eosinophil Count	0.7	5.1	9.5	2.6	1.6	1.3	1.9	2.8	3.1	2.5	2.0	2.3	1.7	2.5
Smoking Status	0.7	1.7	4.4	1.5	0.7	-0.5	1.9	0.3	2.1	1.3	0.9	1.5	1.1	1.1
Supplements: Zinc	0.7	0.7	2.1	1.5	0.9	0.3	0.8	-0.3	0.7	0.7	0.8	1.0	1.2	0.5
Leg fat-free mass (left)	0.7	3.6	7.2	-2.0	-2.2	-2.1	-0.9	-2.7	-0.9	-2.0	-2.2	0.4	-1.6	-2.4
Hayfever, allergic rhinitis or eczema	0.7	1.5	3.0	-1.1	-1.2	-1.0	-1.7	-0.3	-0.5	-1.6	-1.5	-1.5	-1.1	-1.3
Medication: Levothyroxine sodium	0.7	1.2	2.3	0.7	1.2	0.6	1.3	0.7	0.9	1.2	1.5	-0.4	1.3	1.3
Leg predicted mass (left)	0.7	3.9	7.6	-2.0	-2.3	-2.1	-1.1	-2.8	-0.9	-2.1	-2.3	0.4	-1.7	-2.5
Alcohol usually taken with meals	0.7	1.2	2.8	-1.7	-1.3	-0.7	-1.2	-0.0	-0.3	-1.3	-1.5	-0.1	-1.3	-1.0
Had menopause	0.7	0.8	1.7	-1.3	-0.9	-1.0	-0.8	-1.0	-0.4	-1.1	-1.0	-0.2	-0.7	-1.0
Heart attack	0.7	0.9	4.1	0.1	0.2	-0.7	2.0	-1.2	-0.6	-1.2	-0.8	-0.7	0.3	-1.0
Allergy	0.7	1.5	3.3	0.4	1.2	-0.0	1.4	0.9	0.9	1.8	1.8	0.7	1.5	1.5
Diabetes (self-reported)	0.7	1.1	2.5	-1.3	0.9	1.6	-1.0	1.6	-0.0	0.7	1.0	-1.2	0.5	1.0
Medication: Ramipril	0.7	0.9	2.5	0.0	-1.2	-0.8	0.7	-1.6	-0.7	-1.0	-1.1	-0.6	-1.1	-1.0
Fluid intelligence score	0.7	1.5	3.1	-1.0	-0.6	-1.0	-1.0	-1.7	-1.2	-1.8	-1.4	-1.0	-0.8	-1.5
Neuroticism score	0.7	1.4	4.7	-0.2	1.5	0.2	2.2	0.1	1.3	0.8	0.9	0.9	1.9	0.6
Father’s age at death	0.7	1.0	1.6	-0.9	-0.9	-1.2	-1.3	0.7	-0.1	-1.2	-1.3	-0.8	-1.1	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	7.5	-0.4	-1.1	-1.8	-2.2	-2.7	-1.9	-1.1	-1.0	-0.4	-1.0	-1.4
Arm fat mass (right)	0.7	2.8	5.5	-1.9	-2.3	-1.7	-0.7	-1.3	0.2	-1.9	-2.3	0.2	-1.9	-2.0
Birth weight of first child	0.7	1.2	2.4	0.1	-1.0	-1.3	-0.2	-1.6	-0.7	-1.6	-1.5	0.1	-0.9	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.5	-0.3	0.7	0.8	1.1	0.7	0.6	1.6	1.3	-0.3	0.4	1.6
Family relationship satisfaction	0.7	0.9	3.8	2.0	0.6	-0.0	1.6	-0.1	1.2	0.4	0.2	0.8	0.7	0.5
Eye problems/disorders: Cataract	0.7	0.8	3.4	-1.9	-0.2	-1.0	0.3	-0.9	0.2	-1.0	-0.9	0.9	0.3	-1.0
Arm fat mass (left)	0.7	3.0	5.9	-1.7	-2.4	-2.0	-0.6	-1.4	0.1	-2.0	-2.3	0.3	-1.8	-2.2
Financial situation satisfaction	0.7	0.9	3.1	0.0	0.3	1.0	1.6	0.5	1.2	0.8	0.2	1.8	0.2	0.7
Medication: Blood pressure	0.7	1.3	2.9	0.6	-1.1	-1.4	0.2	-1.6	-0.6	-1.6	-1.2	-0.2	-0.5	-1.7
Medication: Bendroflumethiazide	0.7	1.0	3.4	1.8	0.9	-0.3	1.2	-0.3	0.8	0.2	0.5	0.8	1.8	-0.3
Supplements: Calcium	0.7	0.8	2.8	-0.4	-1.3	-0.3	-1.1	-0.4	1.0	0.4	-0.1	1.7	-1.1	0.2
Blood Red Count	0.6	5.4	31.7	0.2	-0.9	-2.4	1.0	3.8	5.6	-0.1	-0.7	2.1	0.5	0.2
Height	0.6	12.2	30.8	-0.4	-2.5	-2.5	-4.6	-5.5	-5.2	-3.4	-2.8	-1.0	-2.7	-3.8
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.8	0.6	-1.2	-1.3	-0.9	0.2	0.4	-0.9	-1.3	-0.2	-1.0	-0.8
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.1	-0.5	-0.7	-0.9	-1.0	-0.8	-0.6	-0.9	-0.8	-0.7	-0.3	-1.1
Impedance of leg (right)	0.6	2.7	4.9	1.5	1.7	2.2	-0.3	2.0	-0.1	2.0	2.1	-1.2	1.0	2.2
Serious illness, injury or assault to yourself	0.6	0.8	2.5	-1.2	-0.7	-0.5	-0.1	-0.7	-1.6	-0.8	-0.6	-0.9	-0.6	-1.0
Had other major operations	0.6	0.7	1.8	-0.7	-0.8	-1.0	-1.1	-0.2	-0.6	-0.7	-0.9	-1.3	-1.0	-0.6
Forced vital capacity (FVC)	0.6	2.4	6.6	0.0	-1.0	-1.9	-1.8	-2.6	-2.1	-1.3	-1.1	0.0	-0.6	-1.8
Time employed in main current job	0.6	0.7	1.9	-0.1	1.4	1.0	0.3	0.6	-0.3	0.7	1.1	-0.9	1.3	0.6
Noisy workplace	0.6	0.7	4.8	-0.5	-0.2	-0.5	-0.0	2.2	1.5	0.1	0.1	0.4	0.1	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.7	0.1	0.4	1.2	0.3	-0.3	0.6	0.7	0.6	1.9	0.5	0.5
Standing height	0.6	5.7	15.4	0.5	-2.2	-1.8	-2.7	-3.9	-3.5	-2.2	-2.0	0.1	-2.2	-2.6
Forced vital capacity (FVC), Best measure	0.6	2.2	8.4	-0.2	-1.2	-1.8	-1.9	-2.9	-1.7	-0.8	-1.0	0.3	-0.9	-1.3
Number of full brothers	0.6	0.7	1.7	1.2	1.0	1.3	0.8	0.9	0.5	0.4	0.5	0.6	0.7	0.7
Neck or shoulder pain in last month	0.6	0.8	2.7	1.6	0.0	0.7	1.0	-0.7	0.8	0.9	0.8	1.2	0.6	0.5
Mean time to correctly identify matches	0.6	1.1	2.4	0.4	1.0	0.6	1.4	0.5	0.3	1.4	1.6	0.9	1.2	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.9	1.4	1.2	0.4	0.5	1.1	1.1	-0.3	0.2	-0.2	1.1	0.3
Supplements: Vitamin C	0.6	0.7	1.9	0.3	-1.3	-0.5	-1.1	-0.3	0.6	-0.0	-0.4	1.1	-1.4	0.2
Knee pain experienced in last month	0.6	1.0	3.5	0.7	0.7	1.0	0.6	0.3	1.3	1.0	0.6	1.9	0.6	1.1
Osteoarthritis (self-reported)	0.6	0.8	5.1	-0.2	0.4	0.3	0.4	2.3	0.6	0.6	0.4	-0.8	-0.3	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	4.3	-0.3	-0.8	-1.2	-1.0	-2.1	-1.2	-1.1	-0.9	-0.4	-0.4	-1.3
Miserableness	0.6	1.1	4.5	-0.3	0.4	-0.4	1.8	1.1	2.1	0.7	0.5	0.8	0.6	0.8
Alcohol drinker status: Never	0.6	0.7	4.0	-1.6	0.6	2.0	-0.1	-0.4	-0.3	0.3	0.7	0.2	0.1	0.7
Crohns Disease (2017)	0.5	1.1	2.1	0.1	-1.3	-1.2	-1.4	-0.8	0.2	-1.2	-1.4	0.4	-1.0	-1.1
Triglycerides	0.5	0.7	1.5	0.6	0.8	1.2	1.1	-0.3	0.1	1.2	1.1	0.0	0.5	1.2
Townsend deprivation index at recruitment	0.5	0.7	3.5	-0.9	-0.2	1.1	-0.4	1.9	0.1	0.5	0.2	-0.3	-1.0	0.9
Maternal smoking around birth	0.5	0.7	2.5	-0.9	-0.9	-1.2	-1.6	-0.4	-0.3	-0.5	-0.7	0.1	-0.5	-0.7
Body mass index (BMI)	0.5	2.2	5.1	-2.3	-2.1	-1.8	0.1	-0.7	0.9	-1.5	-1.9	0.5	-1.4	-1.6
Impedance of leg (left)	0.5	2.5	4.3	1.3	1.8	2.1	-0.4	1.8	-0.6	1.7	2.0	-1.6	0.9	2.0
Hair/balding pattern: Pattern 2	0.5	0.6	1.6	-1.1	-1.0	-0.3	-1.0	0.8	0.7	-0.4	-0.9	-0.2	-1.3	-0.1
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.9	1.7	0.3	0.2	1.3	-0.6	-0.4	0.6	0.5	-0.2	0.3	0.5
Worrier / anxious feelings	0.5	1.0	3.9	0.5	1.0	-0.3	1.7	-0.6	0.4	0.5	0.8	1.0	2.0	-0.2
Tense / ‘highly strung’	0.5	0.8	3.0	0.3	1.4	0.2	1.7	0.1	-0.4	-0.2	0.2	-0.9	1.4	-0.1
High blood pressure (siblings)	0.5	0.8	2.7	0.4	0.4	1.1	-1.1	0.3	0.7	1.1	0.7	1.6	0.1	1.0
Shortness of breath walking on level ground	0.5	0.6	3.4	0.5	-0.4	-0.3	1.2	0.2	1.2	0.3	0.1	1.8	-0.0	0.2
Medication for pain relief, constipation, heartburn	0.5	0.9	2.3	-1.1	-0.3	-0.1	-0.6	-0.4	-1.2	-1.5	-1.2	-0.7	-0.3	-1.3
Medication: Allopurinol	0.5	0.7	2.0	-0.2	-1.1	-1.4	-0.9	-0.3	0.3	-0.6	-0.9	1.0	-0.8	-0.8
Alcohol intake frequency.	0.5	1.1	3.9	-0.2	0.5	0.9	0.4	0.9	2.0	1.2	1.0	1.5	0.6	1.3
Number of full sisters	0.5	0.6	2.9	-0.1	0.3	1.7	0.2	1.1	0.6	0.9	0.6	0.4	0.1	0.9
Suffer from ‘nerves’	0.5	0.8	2.2	-0.3	0.6	-1.1	0.8	1.5	1.3	0.6	0.7	0.8	1.1	0.5
Hypertension (Self-reported)	0.5	1.3	3.3	1.0	-1.1	-1.7	1.0	-1.8	0.6	-0.4	-0.5	1.7	0.1	-1.1
Ever had bowel cancer screening	0.5	0.6	3.1	-1.8	-0.1	-1.2	0.4	0.6	0.3	-0.7	-0.5	-0.6	0.5	-0.7
Ever taken oral contraceptive pill	0.5	0.6	3.4	1.8	-0.1	-0.4	0.6	-0.8	-0.7	0.2	0.5	-0.9	0.2	-0.1
Hearing aid user	0.5	0.6	2.0	0.2	0.6	0.1	1.4	0.1	0.8	0.9	1.0	-0.2	0.9	0.7
High cholesterol (Self-reported)	0.5	0.8	3.5	-1.9	-0.7	-1.3	-0.3	-1.0	-0.1	-0.7	-0.8	0.5	-0.4	-0.9
Vascular/heart problems diagnosed by doctor	0.5	1.3	5.1	-0.6	0.8	1.5	-1.5	2.2	0.1	0.6	0.5	-1.1	-0.2	1.1
Bipolar Disorder or Schizophrenia	0.4	1.0	2.8	1.3	0.8	-0.7	1.7	0.2	1.0	0.7	0.7	0.9	1.5	0.4
Schizophrenia vs Biploar Disorder	0.4	0.6	1.2	-1.0	1.1	-0.0	1.1	0.7	-0.0	-0.1	0.2	-1.1	1.1	0.1
Alzheimer’s Disease (in father)	0.4	0.4	1.1	0.1	1.1	0.5	-0.7	0.2	-0.3	0.8	0.9	0.1	0.8	0.8
Alzheimer’s Disease (including proxy)	0.4	0.6	2.2	1.0	1.1	0.1	0.3	0.4	-0.0	0.4	0.7	-1.5	1.0	0.5
Irritable Bowel Disease (IBD)	0.4	0.9	1.9	-0.8	-1.2	-0.5	-1.2	-0.6	0.2	-1.0	-1.4	0.1	-1.3	-0.7
Reaction Time	0.4	0.8	1.8	0.6	1.0	0.3	1.3	-0.2	-0.5	1.1	1.3	0.4	1.1	0.7
Ovarian Cancer	0.4	0.5	2.6	0.1	-0.0	-0.1	-0.0	-0.3	-1.3	-0.7	-0.6	-1.6	-0.3	-0.7
Lupus	0.4	0.6	2.8	-0.2	-1.1	-0.3	-0.5	0.5	0.9	0.0	-0.4	1.7	-0.9	-0.2
Lung FEV1/FVC ratio	0.4	2.1	7.8	-1.8	0.4	-0.0	-0.9	-1.5	-2.6	-1.0	-0.3	-2.8	-0.2	-0.8
Chronotype (morning person)	0.4	0.9	3.6	-0.3	-0.4	-1.5	-0.8	1.0	1.9	-0.9	-1.1	-0.5	-0.3	-0.4
Number of treatments/medications taken	0.4	0.7	2.9	1.6	0.2	-0.1	1.7	-0.2	0.1	1.0	1.0	0.2	0.5	0.6
Ever had hysterectomy (womb removed)	0.4	0.5	1.9	-1.4	0.0	-0.4	-0.6	0.7	0.8	0.3	0.3	1.3	0.6	0.1
Current tobacco smoking	0.4	0.6	2.0	0.6	0.6	0.1	1.0	0.7	0.5	0.6	0.7	-1.4	0.1	1.0
Taking other prescription medications	0.4	0.6	1.8	-0.1	0.0	0.3	0.8	0.8	1.2	1.3	1.0	0.4	0.2	1.1
Qualifications: CSEs or equivalent	0.4	0.5	2.4	0.6	-0.9	0.1	0.1	1.0	0.5	-0.2	-0.8	-0.1	-1.6	0.3
High blood pressure	0.4	1.0	3.5	0.9	-1.0	-1.3	1.1	-1.9	0.1	-0.4	-0.4	1.4	0.1	-1.0
Multivitamins +/- minerals	0.4	0.5	1.3	0.8	0.6	1.0	0.3	-0.1	-0.1	0.7	0.8	1.1	0.8	0.4
Supplements: Glucosamine	0.4	0.5	3.1	1.8	-0.1	0.1	-0.7	0.4	-0.4	-0.3	-0.3	0.9	-0.5	-0.0
Waist circumference	0.4	1.5	3.9	-1.2	-2.0	-1.7	0.3	-0.7	1.0	-1.1	-1.5	0.6	-1.4	-1.1
Qualifications: None of the above	0.4	0.9	4.0	0.9	0.1	0.1	0.8	1.5	2.0	0.9	0.7	0.5	0.5	0.8
Mouth/teeth dental problems	0.4	0.5	2.8	-0.6	0.1	1.2	-1.7	0.1	-0.6	0.3	0.1	-0.7	-0.5	0.5
Arm fat percentage (right)	0.4	1.7	3.5	-1.6	-1.8	-1.4	0.1	0.0	1.3	-1.5	-1.9	0.4	-1.3	-1.3
Hip circumference	0.4	1.7	4.1	-1.7	-1.8	-2.0	-0.2	-0.8	0.7	-1.3	-1.6	0.7	-1.2	-1.3
Pulse rate	0.4	0.8	2.1	-0.8	-0.8	-1.5	0.1	-0.4	0.0	-1.2	-1.1	0.2	-0.3	-1.3
Illnesses of mother	0.4	0.5	1.7	-1.3	-0.4	-0.7	-0.8	0.7	0.0	-0.6	-0.8	-0.9	-0.7	-0.4
Breastfed as a baby	0.4	0.5	1.4	0.1	0.8	-0.0	0.0	1.2	1.1	0.7	0.5	-0.0	1.1	0.7
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.6	1.4	0.5	0.9	-0.8	1.6	0.3	0.2	0.3	0.1	0.2	0.4
Glaucoma (self-reported)	0.4	0.5	2.4	-0.1	0.5	0.4	-0.9	-0.5	-1.6	-0.2	0.4	-1.1	-0.2	0.2
Age at first live birth	0.4	0.7	2.0	-0.9	-0.7	-1.2	-0.3	-1.4	-0.5	-0.7	-1.0	-0.2	-0.5	-0.9
Qualifications: College or University degree	0.4	1.4	5.4	-1.0	-0.5	-0.5	-0.8	-1.5	-2.3	-1.3	-0.9	-1.0	-0.6	-1.4
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.0	0.5	0.8	0.6	0.8	0.3	-0.1	0.9	1.0	1.0	0.6	0.8
Medication: Blood pressure	0.4	0.7	2.1	-0.5	-0.8	-1.3	0.8	-1.5	-0.4	-0.7	-0.8	0.1	-0.3	-1.0
Medication: Aspirin	0.4	0.5	2.2	-0.7	0.5	-0.0	0.3	-1.5	-1.0	0.8	0.9	0.0	0.5	0.4
Illnesses of father: Heart disease	0.4	0.5	2.0	-1.4	0.3	-0.9	-0.5	0.6	0.9	-0.2	0.1	-1.0	0.7	0.1
Osteoporosis (self-reported)	0.4	0.5	1.4	-1.0	-1.0	-0.3	-0.1	-0.1	-0.2	-0.9	-1.0	0.1	-1.2	-0.7
Medication: Aspirin	0.4	0.6	1.9	-0.8	0.7	0.0	0.3	-1.4	-0.7	0.9	1.0	0.2	0.6	0.6
Medication: Gliclazide	0.4	0.5	2.0	-0.3	0.3	1.4	1.0	-0.2	-0.6	-0.1	0.2	-1.4	0.3	-0.1
Smoking status: Current	0.4	0.7	1.7	0.6	0.7	0.3	1.1	0.7	0.6	0.9	0.9	-1.1	0.1	1.3
Wears glasses or contact lenses	0.4	0.5	1.8	-1.4	-0.6	-0.1	-0.8	-0.5	-0.1	-0.8	-0.8	0.2	-0.6	-0.6
Medication: Paracetamol	0.4	0.6	3.0	1.7	-0.3	0.2	-0.0	1.1	0.5	0.3	0.0	-0.5	-0.9	0.7
Number of operations (self-reported)	0.4	0.5	2.9	0.4	0.7	0.8	1.7	-0.0	-0.2	0.6	0.6	-0.6	0.6	0.5
Fractured/broken bones in last 5 years	0.4	0.6	1.8	0.7	0.1	0.7	1.1	1.3	0.6	0.8	0.5	-0.4	-0.2	0.8
Age started oral contraceptive pill	0.4	0.4	0.8	-0.8	-0.6	-0.5	-0.8	0.0	-0.9	-0.8	-0.8	-0.0	-0.6	-0.8
Impedance of whole body	0.4	1.8	3.1	1.8	1.5	1.7	-0.2	1.6	-0.5	1.2	1.3	-1.6	0.8	1.4
Mean Putamen Volume	0.3	0.3	1.1	-1.0	0.2	-0.5	0.5	0.8	-0.7	-0.6	-0.1	-0.3	0.5	-0.6
HDL Cholesterol	0.3	0.5	1.3	-1.0	-0.9	-0.8	-0.1	-0.2	0.1	-0.9	-0.8	0.3	-0.5	-1.2
LDL Cholesterol	0.3	0.4	1.3	0.2	-0.1	0.7	0.6	0.5	0.7	1.0	0.6	0.1	-0.6	1.1
Neuroticism (2016)	0.3	0.4	2.0	0.1	0.1	-0.7	1.4	-0.4	0.6	-0.1	-0.1	-0.1	0.9	-0.6
Primary Biliary Cirrhosis	0.3	0.4	0.8	0.4	0.6	0.5	-0.0	-0.7	-0.3	0.8	0.8	0.9	0.9	0.3
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.9	-0.1	-0.1	1.4	-1.0	0.4	0.4	0.2	-0.1	-0.2	-0.5	0.6
Heel T-Score	0.3	2.7	8.1	-1.4	-1.9	0.7	-2.8	-0.9	-1.4	-1.2	-1.7	0.7	-2.9	-0.7
Respiratory disease	0.3	0.6	2.2	0.6	-0.5	1.0	0.5	-0.0	1.3	0.3	-0.5	1.5	-0.6	0.3
Average weekly spirits intake	0.3	0.4	1.1	-0.2	-1.0	-1.0	-0.2	-0.0	0.0	-0.0	-0.3	1.0	-0.7	-0.4
Sensitivity / hurt feelings	0.3	0.5	1.2	-0.7	0.9	-0.1	0.8	0.0	0.9	0.8	0.7	-0.4	1.1	0.7
Relative age of first facial hair	0.3	0.7	2.8	-1.7	-0.6	-0.1	-1.6	-0.4	-0.2	0.2	-0.2	0.8	-0.8	-0.1
Vitamin and mineral supplements	0.3	0.4	1.4	-0.7	-0.3	-0.9	-0.3	-0.0	-0.2	-0.7	-0.7	-1.2	-0.3	-0.6
Diabetes (father)	0.3	0.4	0.9	0.8	-0.7	0.3	-0.8	-0.7	-0.7	0.3	0.0	-0.9	-0.9	0.2
Trunk fat mass	0.3	1.2	2.3	-1.1	-1.5	-1.3	-0.3	-0.6	0.2	-1.3	-1.5	-0.5	-1.1	-1.3
Number of incorrect matches in round	0.3	0.5	1.4	1.1	0.5	0.3	1.2	0.0	-0.4	0.5	0.9	-0.3	0.7	0.1
Financial difficulties in last 2 years	0.3	0.4	1.8	-0.9	0.0	0.6	0.5	1.3	0.6	0.1	-0.2	-0.5	-0.3	0.3
Medication: Simvastatin	0.3	0.5	3.3	-1.8	-0.6	-0.2	-0.2	0.2	0.4	-0.2	-0.4	-0.7	-0.7	0.0
Medication: Cholesterol lowering	0.3	0.5	2.9	-1.7	-0.1	-0.1	0.5	-1.5	-0.4	-0.0	-0.2	0.0	-0.1	-0.2
Impedance of arm (left)	0.3	1.3	3.8	2.0	1.3	1.5	0.6	1.4	-0.1	0.8	0.9	-1.2	0.8	1.0
Pulse wave reflection index	0.3	0.4	2.1	-0.7	0.6	0.5	0.0	-0.4	-0.6	0.3	0.5	-1.5	-0.0	0.6
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.9	0.8	0.2	0.2	1.4	0.1	0.7	0.6	0.4	0.1	0.6	0.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.7	1.3	0.3	-0.4	0.3	0.9	0.9	0.2	0.0	0.4	0.5	0.3
Headache pain in last month	0.3	0.5	3.1	-0.1	-0.4	-0.9	-0.2	0.2	0.8	-0.2	-0.2	1.8	-0.1	-0.3
Gout (self-reported)	0.3	0.5	1.7	0.2	0.1	-0.4	0.1	1.3	1.3	0.5	0.2	1.0	0.2	0.5
Worry too long after embarrassment	0.3	0.5	3.2	-1.8	0.4	-0.5	0.5	-0.4	-0.0	-0.0	0.1	0.4	0.9	-0.4
Health satisfaction	0.3	0.3	1.0	0.6	-0.9	0.6	0.6	0.4	0.4	0.5	0.0	0.4	-1.0	0.4
Eye problems/disorders: None of the above	0.3	0.4	1.2	1.0	-0.9	-0.3	0.3	-0.0	-0.2	-0.2	-0.6	-0.7	-1.1	-0.3
Medication: Omeprazole	0.3	0.4	1.5	0.4	-0.2	0.5	1.1	1.2	0.9	0.4	0.3	0.3	-0.0	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.6	-0.3	0.7	0.8	0.7	0.7	0.4	0.2	0.2	0.6	0.8	0.1
Arm fat percentage (left)	0.3	1.2	2.5	-1.4	-1.6	-1.2	0.4	0.0	1.1	-1.2	-1.6	0.2	-1.1	-1.2
Average weekly red wine intake	0.3	0.4	1.8	0.5	-0.3	0.4	-1.3	-0.5	-0.2	0.2	-0.2	1.3	-0.5	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.4	-0.6	-0.6	-1.2	0.4	0.5	0.4	-1.0	-0.9	-0.6	-0.2	-0.9
Asthma (self-reported)	0.3	0.5	1.9	0.1	0.0	1.4	1.1	-0.1	1.1	0.1	-0.4	1.1	-0.1	0.1
Average weekly champagne plus white wine intake	0.3	0.4	1.8	-0.2	0.2	1.3	1.0	-0.0	-1.2	0.3	0.3	-0.3	-0.1	0.2
Mother’s age at death	0.3	0.3	0.8	0.2	-0.5	-0.7	0.3	-0.5	-0.4	-0.9	-0.6	0.8	-0.5	-0.7
Medication: Atorvastatin	0.3	0.4	1.2	-0.8	0.4	-0.3	0.9	-1.1	-0.5	-0.1	0.1	-0.7	0.5	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.0	-0.6	0.6	0.3	0.4	0.5	1.0	0.4	0.4	0.5	0.9	0.4
Pack years of smoking	0.3	0.4	1.2	-0.2	-0.4	0.0	-1.1	0.7	0.9	0.7	0.1	-0.5	-0.7	0.8
Leg fat mass (left)	0.3	1.2	3.9	-2.0	-1.5	-1.0	-0.6	-0.7	0.2	-1.0	-1.2	-0.0	-1.1	-1.0
Major Depression (MDD)	0.2	0.2	0.9	0.1	-0.5	0.1	-0.9	-0.6	-0.5	0.2	-0.1	0.7	-0.4	-0.1
Age at First Birth	0.2	0.3	0.5	-0.6	0.6	-0.5	-0.0	0.3	0.6	0.7	0.5	-0.4	0.5	0.7
Bipolar Disorder (2011)	0.2	0.2	0.4	0.0	-0.5	-0.5	0.4	-0.5	-0.2	-0.4	-0.3	0.2	-0.1	-0.6
HbA1C	0.2	0.3	1.3	0.3	-0.2	0.4	-0.4	-0.6	-1.1	0.5	0.4	-0.5	-0.1	-0.2
Schizophrenia (2014)	0.2	0.5	1.4	0.9	0.6	-1.2	1.0	-0.1	0.5	0.0	0.2	0.3	1.1	-0.1
Ulcerative Colitis	0.2	0.2	0.6	0.5	0.2	0.6	0.0	-0.7	0.7	0.4	0.1	0.8	0.1	0.4
Blood White Count	0.2	1.7	7.2	0.3	-1.0	0.5	-0.0	2.6	2.7	0.9	0.1	0.6	-1.0	1.2
BMI	0.2	1.1	2.3	-1.4	-1.5	-0.8	0.2	-0.2	1.3	-0.6	-1.1	1.4	-1.1	-0.6
Cardiovascular Disease	0.2	0.5	2.3	0.2	-0.2	-0.0	1.0	-1.5	0.1	0.2	0.2	1.5	0.1	-0.0
Lung FVC	0.2	1.2	3.4	-0.5	-0.4	-1.5	-0.5	-1.5	-1.6	-0.6	-0.5	-1.8	-0.2	-1.0
Hearing difficulty/problems: Yes	0.2	0.3	1.1	-0.6	0.6	-0.1	1.0	-0.6	0.2	0.1	0.3	-0.0	1.0	-0.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.3	0.0	-0.1	-0.1	1.1	-0.8	0.4	0.6	0.3	0.2	0.2	0.3
Diabetes (mother)	0.2	0.2	1.3	0.3	0.1	0.2	0.7	-0.4	-0.5	-0.1	-0.2	-1.1	-0.1	0.0
Pack years adult smoking proportion	0.2	0.4	1.0	-0.1	-0.3	0.1	-0.8	0.7	1.0	0.7	0.2	-0.2	-0.6	0.9
Trunk fat percentage	0.2	0.8	1.4	-1.2	-1.1	-0.9	-0.0	0.2	0.6	-1.0	-1.2	-1.0	-0.8	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.1	-1.5	0.5	1.1	0.1	-1.0	-0.8	0.2	0.4	-0.3	0.2	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.7	-0.8	0.1	1.3	0.1	-1.1	-1.0	-0.3	-0.1	0.1	-0.0	-0.3
Impedance of arm (right)	0.2	1.1	2.8	1.7	1.2	1.5	0.4	1.2	0.2	0.8	0.9	-0.7	0.7	1.0
Number of live births	0.2	0.3	0.8	-0.7	-0.2	-0.1	-0.5	0.7	0.2	-0.4	-0.7	-0.9	-0.4	-0.1
Asthma	0.2	0.4	1.7	-0.1	-0.3	1.3	0.7	-0.2	0.8	-0.2	-0.6	0.9	-0.5	-0.1
Exposure to tobacco smoke at home	0.2	0.3	0.8	-0.7	0.2	-0.6	-0.3	0.9	0.9	0.2	0.2	0.3	0.3	0.3
Peak expiratory flow (PEF)	0.2	0.4	1.5	0.8	-0.1	-1.2	0.1	-0.9	-0.7	-0.6	-0.2	-0.1	0.3	-0.6
Loud music exposure frequency	0.2	0.2	1.4	-0.2	0.4	-0.1	0.6	-1.2	-0.6	-0.4	-0.1	0.1	0.3	-0.2
Medication: Paracetamol	0.2	0.3	1.7	0.2	-0.7	-0.2	-0.4	0.1	0.0	-0.3	-0.5	-0.9	-1.3	0.0
Medication: Amlodipine	0.2	0.3	0.8	-0.1	-0.9	-0.6	-0.6	-0.7	-0.5	-0.2	-0.3	-0.4	-0.8	-0.4
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.0	-0.4	0.3	0.1	1.0	1.0	0.3	0.1	0.3	-0.5	0.1	0.4
Body fat percentage	0.2	0.7	1.8	-1.3	-1.0	-0.8	0.1	0.6	1.2	-0.7	-0.9	-0.3	-0.7	-0.5
Comparative body size at age 10	0.2	0.7	2.3	1.0	-0.0	0.4	1.4	-1.5	0.6	0.7	0.2	0.8	0.1	0.5
Heart disease (mother)	0.2	0.3	1.3	0.6	-0.0	-0.3	-0.5	0.8	0.6	0.2	-0.0	1.1	0.3	0.1
Whole body fat mass	0.2	1.0	2.2	-1.5	-1.4	-1.1	-0.2	-0.4	0.6	-1.0	-1.3	0.0	-1.0	-1.0
Leg fat mass (right)	0.2	0.9	3.2	-1.8	-1.4	-0.8	-0.5	-0.6	0.4	-0.7	-1.0	0.2	-1.1	-0.8
Comparative height size at age 10	0.2	1.2	8.1	-0.2	-0.2	0.1	0.0	-2.8	-2.0	-0.3	-0.0	0.2	-0.4	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.6	0.0	-0.5	0.3	0.5	0.4	-0.7	-0.4	-0.2	-0.6	-0.7	-0.3
Medication: Lisinopril	0.2	0.3	1.1	0.6	0.1	0.6	0.7	-0.6	-0.6	-0.1	0.2	1.0	0.5	-0.4
Leg fat percentage (left)	0.2	0.5	3.0	-1.7	-0.8	-0.4	-0.4	0.6	0.9	-0.3	-0.5	-0.1	-0.6	-0.1
Risk taking	0.2	0.3	1.0	-0.2	0.0	-0.4	-0.7	0.7	1.0	0.5	0.3	-0.3	-0.0	0.7
Diastolic blood pressure, automated reading	0.2	0.5	2.1	1.2	0.3	-0.4	1.4	-0.5	0.6	0.4	0.4	0.5	0.8	-0.1
Cholesterol lowering medication	0.2	0.2	1.6	-1.3	-0.1	-0.7	0.1	0.1	0.3	-0.1	0.0	0.0	0.5	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.9	0.5	-0.0	0.9	0.8	0.9	0.3	0.4	0.4	-0.0	-0.0	0.4
Schizophrenia (2018)	0.1	0.2	0.8	-0.2	0.3	-0.9	0.9	0.4	0.6	-0.0	-0.0	-0.1	0.6	-0.0
Ulcerative Colitis (UC)	0.1	0.2	0.6	-0.7	-0.5	0.3	-0.6	0.1	0.3	-0.1	-0.4	0.1	-0.7	0.1
Prostate Cancer	0.1	0.2	1.0	1.0	0.3	0.3	0.1	-0.5	-0.2	0.1	0.1	0.6	0.5	-0.2
Waist Hip Ratio (WHR)	0.1	0.5	2.1	0.8	-0.5	-0.4	0.1	-0.7	-0.9	-0.4	-0.2	-1.4	-0.7	-0.4
Systolic Blood Pressure	0.1	0.4	2.5	0.5	0.2	0.5	0.3	-1.6	-0.6	0.4	0.4	-0.7	0.0	0.2
Hair Pigment	0.1	2.3	5.1	1.7	1.6	1.8	0.8	-1.8	-2.3	1.3	1.9	0.3	1.3	0.9
Tanning	0.1	1.7	8.6	1.3	0.4	-0.4	1.2	2.9	2.2	0.2	0.4	0.3	0.5	0.9
Systolic blood pressure, automated reading	0.1	0.2	1.5	1.2	-0.2	-0.0	0.3	-0.5	0.5	0.6	0.3	0.2	0.1	0.2
Age when periods started (menarche)	0.1	0.3	1.5	1.2	-0.8	-0.9	0.2	0.2	0.0	-0.1	-0.1	0.4	-0.2	-0.5
Hearing difficulty/problems with background noise	0.1	0.1	0.6	-0.2	0.4	0.4	0.2	-0.7	-0.2	0.2	0.2	-0.0	0.4	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.8	0.3	0.1	-0.9	0.3	-0.3	0.3	-0.1	0.2	-0.4	0.2	0.1
Leg fat percentage (right)	0.1	0.5	2.6	-1.6	-0.8	-0.3	-0.1	0.7	1.2	-0.0	-0.3	0.3	-0.5	0.0
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	0.3	-0.4	0.6	0.1	0.3	0.4	-0.3	-0.7	-0.0	-0.6	-0.1
Number of children fathered	0.1	0.1	0.5	-0.2	0.6	-0.5	-0.4	0.1	0.2	-0.3	0.0	0.3	0.7	-0.1
Commuting to job workplace: Cycle	0.1	0.1	0.4	-0.4	0.6	-0.4	0.4	-0.3	-0.4	-0.1	0.3	-0.3	0.5	0.1
Alcohol drinker status: Previous	0.1	0.1	0.5	-0.3	-0.0	0.1	0.1	0.5	0.7	0.1	-0.0	0.2	0.1	0.2
Hypothyroidism (self reported)	0.0	0.1	0.4	0.1	0.2	-0.7	0.1	-0.0	0.5	-0.2	0.1	-0.5	0.2	0.1

Hub : Genes

VTI1B

Models

Trait associations